proline and acetylcysteine

proline has been researched along with acetylcysteine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.25)18.7374
1990's2 (6.25)18.2507
2000's19 (59.38)29.6817
2010's9 (28.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bud, JM; Hjortsø, E; Jensen, N; Qvist, J; Thomsen, JL1
Stiel, L; Wapnir, RA1
Faller, DV; Phelan, MW1
Ahmad, M; Li, WQ; Morin, I; Su, S; Zafarullah, M1
Chen, KD; Chen, LY; Cho, JH; Lai, MT; Lai, YK1
Baier-Bitterlich, G; Böck, G; Fuchs, D; Spöttl, N; Widner, B; Wirleitner, B1
Bai, W; Guha, M; Nadler, JL; Natarajan, R1
Carthy, CM; Granville, DJ; Hunt, DW; Jolois, O; Matroule, JY; Piette, J1
Ashida, H; Danno, G; Endo, T; Fukuda, I; Hashizume, K; Hatanaka, Y; Sano, T; Suzukia, K; Tani, Y; Yamaguchi, Y1
Bachi, A; Burri, L; Hellman, U; Lévy, F; Lévy, N; Morel, S; Peitrequin, AL; Servis, C; Van den Eynde, BJ1
Abe, S; Desaki, M; Kawasaki, S; Kohyama, T; Kudoh, S; Matsushima, K; Nakahara, K; Ohtoshi, T; Okazaki, H; Sagai, M; Saito, Y; Sugawara, I; Takizawa, H; Tanaka, M; Yamamoto, K1
Nikinmaa, M; Pursiheimo, S; Soitamo, AJ1
Khan, M; Pannu, R; Singh, AK; Singh, I; Won, JS1
Cheng, YW; Kang, JJ; Lee, CC1
Jana, M; Pahan, K1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW3
Abu-El-Ardat, K; Diab-Assaf, M; Harakeh, S; Khalife, J; Niedzwiecki, A; Rath, M1
Bieri, M; Bürgi, T1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Fujigaki, Y; Hishida, A; Luo, J; Sun, Y; Tsuji, T; Yasuda, H1
Gangapurkar, B; Jariwalla, RJ; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, B1
Blalock, JE; Brown, MD; Hardison, MT; Jackson, P; Snelgrove, RJ1
Chen, G; Chen, J; Chen, P; Feng, J; Guo, R; Hua, X; Mo, L; Wu, K; Xu, W; Zheng, D1
Choi, IW; Choi, YH; Dilshara, MG; Kim, GY; Lee, CM; Lee, HJ; Lee, KT1
Myöhänen, TT; Norrbacka, S; Savolainen, MH1
Chan, PC; Chen, YL; Hsieh, PS; Hsu, WN; Tian, YF; Wang, YC1
Domoto, R; Kawabata, A; Nakashima, K; Nishibori, M; Sekiguchi, F; Tsubota, M; Wake, H; Yamanishi, H; Yamasoba, D1
Andrulewicz-Botulinska, E; Hlebowicz-Sarat, K; Karna, E; Palka, JA; Szoka, L1
Lindholm, D; Myöhänen, TT; Norrbacka, S1

Other Studies

32 other study(ies) available for proline and acetylcysteine

ArticleYear
[Zinc chloride poisoning--observations and treatment].
    Nordisk medicin, 1988, Volume: 103, Issue:2

    Topics: Acetylcysteine; Adult; Chlorides; Humans; Male; Military Personnel; Proline; Zinc; Zinc Compounds

1988
Zinc intestinal absorption in rats: specificity of amino acids as ligands.
    The Journal of nutrition, 1986, Volume: 116, Issue:11

    Topics: Acetylcysteine; Amino Acids; Animals; Colon; Cysteine; Histidine; Ileum; Imidazoles; Indoles; Intestinal Absorption; Jejunum; Kinetics; Male; Proline; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Tryptophan; Zinc

1986
Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells.
    Journal of cellular physiology, 1996, Volume: 167, Issue:3

    Topics: Acetylcysteine; Animals; Bradykinin; Cattle; Cell Hypoxia; Cells, Cultured; Cobalt; Dactinomycin; Endothelin-1; Endothelins; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Nitric Oxide Synthase; Oxygen; Proline; Protein Precursors; RNA, Messenger; Suppression, Genetic; Thiocarbamates; Umbilical Veins

1996
Induction of stromelysin gene expression by tumor necrosis factor alpha is inhibited by dexamethasone, salicylate, and N-acetylcysteine in synovial fibroblasts.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cattle; Cells, Cultured; Dexamethasone; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Ibuprofen; Indomethacin; Matrix Metalloproteinase 3; Proline; Sodium Salicylate; Synovial Membrane; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vitamin E

1999
Activation of p38 mitogen-activated protein kinase and mitochondrial Ca(2+)-mediated oxidative stress are essential for the enhanced expression of grp78 induced by the protein phosphatase inhibitors okadaic acid and calyculin A.
    Journal of cellular biochemistry, 2000, Volume: 76, Issue:4

    Topics: Acetylcysteine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Egtazic Acid; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Imidazoles; Marine Toxins; Mitochondria; Mitogen-Activated Protein Kinases; Molecular Chaperones; Okadaic Acid; Oxazoles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Proline; Promoter Regions, Genetic; Pyridines; Rats; RNA, Messenger; Ruthenium Red; Thiocarbamates; Transcriptional Activation; Tumor Cells, Cultured

2000
Reduced pteridine derivatives induce apoptosis in human neuronal NT2/HNT cells.
    Immunobiology, 2000, Volume: 201, Issue:3-4

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Catalase; Humans; Neurons; Oxidative Stress; Proline; Pteridines; Thiocarbamates; Tumor Cells, Cultured

2000
Molecular mechanisms of tumor necrosis factor alpha gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and -independent pathways.
    The Journal of biological chemistry, 2000, Jun-09, Volume: 275, Issue:23

    Topics: Acetylcysteine; Cell Line; Gene Expression Regulation; Glucose; Humans; Hyperglycemia; Imidazoles; Luminescent Measurements; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proline; Pyridines; Reactive Oxygen Species; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1; Transcription, Genetic; Tumor Necrosis Factor-alpha; U937 Cells

2000
Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization.
    Oncogene, 2001, Jul-05, Volume: 20, Issue:30

    Topics: Acetylcysteine; Adenocarcinoma; Antioxidants; Apoptosis; Caspase 3; Caspases; Ceramides; Chloroquine; Colonic Neoplasms; Cytochrome c Group; Deuterium Oxide; Endoplasmic Reticulum; Gene Expression Regulation, Neoplastic; Golgi Apparatus; Humans; Lysosomes; Mannans; Mannosephosphates; Microscopy, Fluorescence; Mitochondria; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Oxygen; Phosphorylation; Photochemistry; Photosensitizing Agents; Proline; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Radiation-Protective Agents; Reactive Oxygen Species; Second Messenger Systems; Singlet Oxygen; Thiocarbamates; Tumor Cells, Cultured

2001
Up-regulation of CD13/aminopeptidase N induced by phorbol ester is involved in redox regulation and tumor necrosis factor alpha production in HL-60 cells.
    Inflammation, 2002, Volume: 26, Issue:4

    Topics: Acetylcysteine; Antioxidants; CD13 Antigens; Cytokines; HL-60 Cells; Humans; Inflammation Mediators; Oxidation-Reduction; Proline; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thiocarbamates; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation

2002
The final N-terminal trimming of a subaminoterminal proline-containing HLA class I-restricted antigenic peptide in the cytosol is mediated by two peptidases.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Oct-15, Volume: 169, Issue:8

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Aminopeptidases; Antigen Presentation; Cell Line; Cytosol; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enzyme Inhibitors; HLA-B Antigens; HLA-B51 Antigen; Humans; Hydrolysis; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Proline; Protein Precursors; Protein Processing, Post-Translational; Puromycin; Serine Endopeptidases; T-Lymphocytes, Cytotoxic; Transfection; Tumor Cells, Cultured

2002
Diesel exhaust particles upregulate eotaxin gene expression in human bronchial epithelial cells via nuclear factor-kappa B-dependent pathway.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:6

    Topics: Acetylcysteine; Antibodies; Antioxidants; Bronchi; Cells, Cultured; Chemokine CCL11; Chemokines, CC; Electrophoretic Mobility Shift Assay; Epithelial Cells; Expectorants; Gene Expression; Humans; In Vitro Techniques; Interleukin-13; NF-kappa B; Proline; Respiratory Mucosa; RNA, Messenger; Signal Transduction; STAT6 Transcription Factor; Thiocarbamates; Trans-Activators; Up-Regulation; Vehicle Emissions

2003
Redox state regulates HIF-1alpha and its DNA binding and phosphorylation in salmonid cells.
    Journal of cell science, 2004, Jul-01, Volume: 117, Issue:Pt 15

    Topics: Acetylcysteine; Animals; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Cell Line; Cysteine; Dimerization; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Immunoprecipitation; Oncorhynchus mykiss; Oxidation-Reduction; Oxidative Stress; Oxygen; Phosphorylation; Proline; Propyl Gallate; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; RNA; Time Factors; Transcription Factors; Transcriptional Activation

2004
A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jun-30, Volume: 24, Issue:26

    Topics: Acetylcysteine; Animals; Antigens, CD; Antioxidants; Apoptosis; Astrocytes; Cells, Cultured; Demyelinating Diseases; Drug Evaluation, Preclinical; Enzyme Induction; Enzyme Inhibitors; Fatty Acids; Female; Gait Disorders, Neurologic; Galactosyltransferases; I-kappa B Proteins; Inflammation; Interferon-gamma; Lactosylceramides; Lipopolysaccharides; Morpholines; Nerve Tissue Proteins; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Phosphorylation; Proline; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Spinal Cord Injuries; Thiocarbamates; Transfection

2004
Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells.
    Journal of toxicology and environmental health. Part A, 2005, Volume: 68, Issue:17-18

    Topics: Acetylcysteine; Anthracenes; Cell Line, Tumor; Cell Survival; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Interleukin-8; Motorcycles; NF-kappa B; Proline; RNA, Messenger; Thiocarbamates; Vehicle Emissions

2005
Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes.
    Free radical biology & medicine, 2005, Sep-15, Volume: 39, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Humans; Hydrogen Peroxide; Inflammation; Interleukin-1; Mice; Multiple Sclerosis; Myelin Basic Protein; Myelin Proteins; Myelin Proteolipid Protein; Myelin Sheath; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neuroglia; Oligodendroglia; Oxidants; Oxidation-Reduction; Phosphoric Diester Hydrolases; Proline; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sulfhydryl Compounds; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha

2005
Anti-angiogenic effects of a nutrient mixture on human umbilical vein endothelial cells.
    Oncology reports, 2005, Volume: 14, Issue:6

    Topics: Acetylcysteine; Angiogenesis Inhibitors; Arginine; Ascorbic Acid; Capillaries; Cell Line; Cell Movement; Cell Proliferation; Copper; Culture Media; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Lysine; Manganese; Matrix Metalloproteinase 2; Plant Extracts; Proline; Selenium; Tea; Umbilical Veins

2005
Apoptosis induction by Epican Forte in HTLV-1 positive and negative malignant T-cells.
    Leukemia research, 2006, Volume: 30, Issue:7

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arginine; Ascorbic Acid; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Copper; Dietary Supplements; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Profiling; Human T-lymphotropic virus 1; Humans; Lysine; Manganese; Proline; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Sensitivity and Specificity; Structure-Activity Relationship; T-Lymphocytes; Transforming Growth Factors

2006
Enantiodiscrimination between an N-acetyl-L-cysteine SAM and proline: an in situ spectroscopic and computational study.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2006, Feb-13, Volume: 7, Issue:2

    Topics: Acetylcysteine; Computer Simulation; Models, Molecular; Molecular Structure; Proline; Spectrophotometry, Infrared; Stereoisomerism; Vibration

2006
Inhibition of glioma cell line A-172 MMP activity and cell invasion in vitro by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:2

    Topics: Acetylcysteine; Amino Acids; Antineoplastic Agents; Arginine; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Drug Combinations; Glioma; Humans; Laminin; Lysine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans

2007
Inhibition of 7,12-dimethylbenzanthracene-induced skin tumors by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Amino Acids; Animals; Arginine; Ascorbic Acid; Camellia sinensis; Carcinogens; Copper; Diet; Female; Keratoacanthoma; Lysine; Manganese; Mice; Mice, Inbred SENCAR; Papilloma; Plant Extracts; Proline; Selenium; Skin; Skin Neoplasms

2008
The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:7

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Cross-Linking Reagents; Disease Models, Animal; Free Radical Scavengers; Male; Melatonin; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proline; Rats; Rats, Sprague-Dawley; Thiocarbamates; Tumor Necrosis Factor-alpha

2008
A nutrient mixture prevents acetaminophen hepatic and renal toxicity in ICR mice.
    Human & experimental toxicology, 2008, Volume: 27, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Ascorbic Acid; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatinine; Kidney; Liver; Lysine; Male; Mice; Mice, Inbred ICR; Organ Size; Proline; Tea

2008
Suppression of influenza A virus nuclear antigen production and neuraminidase activity by a nutrient mixture containing ascorbic acid, green tea extract and amino acids.
    BioFactors (Oxford, England), 2007, Volume: 31, Issue:1

    Topics: Acetylcysteine; Animals; Antigens, Viral; Ascorbic Acid; Cell Line; Cell Survival; Chlorocebus aethiops; Culture Media; Dogs; Flavonoids; Influenza A virus; Lysine; Neuraminidase; Nucleocapsid Proteins; Phenols; Polyphenols; Proline; RNA-Binding Proteins; Tea; Vero Cells; Viral Core Proteins

2007
Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 27, Issue:1

    Topics: Acetylcysteine; Angiotensin II; Antihypertensive Agents; C-Reactive Protein; Flavonoids; Humans; Imidazoles; Losartan; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Thiocarbamates; U937 Cells

2011
Cigarette smoke enhances chemotaxis via acetylation of proline-glycine-proline.
    Frontiers in bioscience (Elite edition), 2012, 06-01, Volume: 4, Issue:7

    Topics: Acetylation; Acetylcysteine; Carbocysteine; Chemotaxis, Leukocyte; Humans; Neutrophils; Nicotiana; Oligopeptides; Proline; Smoke

2012
Exogenous hydrogen sulfide protects against doxorubicin-induced inflammation and cytotoxicity by inhibiting p38MAPK/NFκB pathway in H9c2 cardiac cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 32, Issue:6

    Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Doxorubicin; Inflammation; Interleukin-1beta; Interleukin-6; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Rats; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Sulfites; Thiocarbamates; Tumor Necrosis Factor-alpha

2013
New compound, 5-O-isoferuloyl-2-deoxy-D-ribono-γ-lacton from Clematis mandshurica: Anti-inflammatory effects in lipopolysaccharide-stimulated BV2 microglial cells.
    International immunopharmacology, 2015, Volume: 24, Issue:1

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Clematis; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Heme Oxygenase-1; Lactones; Lipopolysaccharides; Membrane Proteins; Mice; Microglia; Nervous System Diseases; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phytotherapy; Plant Roots; Proline; Reactive Oxygen Species; Ribose; Signal Transduction; Thiocarbamates

2015
Prolyl oligopeptidase inhibition attenuates the toxicity of a proteasomal inhibitor, lactacystin, in the alpha-synuclein overexpressing cell culture.
    Neuroscience letters, 2017, 01-01, Volume: 636

    Topics: Acetylcysteine; alpha-Synuclein; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Mutation; Proline; Prolyl Oligopeptidases; Proteasome Inhibitors; Protein Aggregates; Serine Endopeptidases; Serine Proteinase Inhibitors

2017
Importance of NADPH oxidase-mediated redox signaling in the detrimental effect of CRP on pancreatic insulin secretion.
    Free radical biology & medicine, 2017, Volume: 112

    Topics: Acetophenones; Acetylcysteine; Animals; C-Reactive Protein; Cell Line; Dose-Response Relationship, Drug; Etanercept; Gene Expression Regulation; Guanidines; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred BALB C; NADPH Oxidases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Oxidation-Reduction; Proline; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha; Tyrosine

2017
Paclitaxel-induced HMGB1 release from macrophages and its implication for peripheral neuropathy in mice: Evidence for a neuroimmune crosstalk.
    Neuropharmacology, 2018, Volume: 141

    Topics: Acetylcysteine; Animals; Antibodies; Cells, Cultured; Clodronic Acid; Coculture Techniques; Ganglia, Spinal; HMGB1 Protein; Hyperalgesia; Imidazoles; Macrophages; Male; Membrane Proteins; Mice; Minocycline; Neurons; p300-CBP Transcription Factors; Paclitaxel; Peripheral Nervous System Diseases; Phosphoproteins; Phosphorylation; Proline; Pyridines; Pyruvates; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, CXCR4; Recombinant Proteins; Sciatic Nerve; Thiocarbamates; Thrombomodulin; Up-Regulation

2018
The mechanism for differential effect of nelfinavir and indinavir on collagen metabolism in human skin fibroblasts.
    Experimental dermatology, 2019, Volume: 28, Issue:7

    Topics: Acetylcysteine; Ascorbic Acid; Cell Survival; Collagen; Dipeptidases; DNA; Down-Regulation; Fibroblasts; Glutamine; HIV Protease Inhibitors; Humans; Indinavir; Nelfinavir; NF-kappa B p50 Subunit; Phosphatidylinositol 3-Kinases; Phosphorylation; Proline; Skin; Wortmannin

2019
Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington's disease.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:12

    Topics: Acetylcysteine; Biocatalysis; Cell Survival; Cysteine Proteinase Inhibitors; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Peptides; Proline; Prolyl Oligopeptidases; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Aggregation, Pathological; Serine Endopeptidases; Trinucleotide Repeats

2019