proline has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (69.23) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Carlberg, K; Chen, Y; Grey, A; Insogna, K; Paliwal, I | 1 |
| Kovacina, KS; Roth, RA; Shimaya, A | 1 |
| Gardner, CR; Gerecke, DR; Hanna, N; Heck, DE; Laskin, DL; Laskin, JD; Weinberger, B | 1 |
| Charoenfuprasert, S; Fan, CW; Leu, TH; Maa, MC; Yen, CK | 1 |
| Chao, CM; Chen, BC; Ho, FM; Lai, CC; Liau, CS; Lin, LY; Lin, WW; Liu, SH; Yang, CR | 1 |
| Jimenez Del Rio, M; Velez-Pardo, C | 1 |
| Faubel, S; Gengaro, P; Li, C; Rivard, C; Schrier, RW; Wang, W; Wang, XQ; Zhou, Z | 1 |
| Chen, CY; Chen, WC; Fong, YC; Hsu, SF; Huang, CY; Kao, ST; Li, TM; Liu, SC; Tang, CH; Tsai, FJ | 1 |
| Guo, SY; Jiang, DJ; Song, T; Sun, ZQ; Tan, XH; Wang, F; Yang, GP | 1 |
| Chiu, YC; Fu, WM; Lin, TH; Liou, HC; Wu, MY; Yang, RS | 1 |
| Gao, F; Li, F; Li, XY; Liu, ST; Miao, Y; Sun, XH; Wang, X; Wang, Z; Yang, XL; Zhang, ML; Zhong, SM; Zhu, K | 1 |
| Deng, X; Gao, T; Guo, Q; Kenechukwu, AA; Kuguminkiriza, IH; Na, M; Yong, W; Yu, H; Zhang, G; Zhang, Y | 1 |
13 other study(ies) available for proline and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Evidence for a functional association between phosphatidylinositol 3-kinase and c-src in the spreading response of osteoclasts to colony-stimulating factor-1.
Topics: Androstadienes; Animals; Binding Sites; Cell Movement; Chromones; Enzyme Inhibitors; Immunosorbent Techniques; Macrophage Colony-Stimulating Factor; Mice; Morpholines; Osteoclasts; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Proto-Oncogene Proteins pp60(c-src); Rats; Receptor, Macrophage Colony-Stimulating Factor; Regulatory Sequences, Nucleic Acid; src Homology Domains; Wortmannin | 2000 |
On the mechanism for neomycin reversal of wortmannin inhibition of insulin stimulation of glucose uptake.
Topics: 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Anti-Bacterial Agents; CHO Cells; Chromones; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Glycogen Synthase Kinase 3; Humans; Immunoblotting; Insulin; Mice; Morpholines; Neomycin; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein Transport; Ribosomal Protein S6; Time Factors; Wortmannin | 2004 |
Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophils.
Topics: Apoptosis; Calcium; Cells, Cultured; Chemotaxis, Leukocyte; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Humans; Hydroxyproline; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Signal Transduction; Structure-Activity Relationship | 2005 |
Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages.
Topics: Animals; Cell Line; Chromones; Cyclooxygenase 2; Endotoxemia; Flavonoids; Gene Expression Regulation; Genes, src; Lipopolysaccharides; Macrophage Activation; Macrophages; Macrophages, Peritoneal; Mice; Morpholines; NF-kappa B; Nitric Oxide; Peritonitis; Phosphoinositide-3 Kinase Inhibitors; Proline; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases; Thiocarbamates; Tumor Necrosis Factor-alpha | 2006 |
High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway.
Topics: Androstadienes; Apoptosis; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Chromones; Endothelial Cells; Female; Gene Expression Regulation; Glucose; Humans; JNK Mitogen-Activated Protein Kinases; Morpholines; Mutation; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroarginine; Nitroprusside; Oligonucleotides, Antisense; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proline; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Umbilical Veins; Wortmannin | 2006 |
Insulin-like growth factor-1 prevents Abeta[25-35]/(H2O2)- induced apoptosis in lymphocytes by reciprocal NF-kappaB activation and p53 inhibition via PI3K-dependent pathway.
Topics: Adult; Amyloid beta-Peptides; Apoptosis; Benzothiazoles; Chromones; Humans; Hydrogen Peroxide; In Vitro Techniques; Insulin-Like Growth Factor I; Lymphocytes; Male; Mitochondrial Membranes; Morpholines; NF-kappa B; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Thiazoles; Thiocarbamates; Toluene; Tumor Suppressor Protein p53; Up-Regulation | 2006 |
Role of NF-kappaB and PI 3-kinase/Akt in TNF-alpha-induced cytotoxicity in microvascular endothelial cells.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Chromones; Endothelial Cells; Endotoxemia; Enzyme Inhibitors; Interleukin-1beta; Interleukin-6; MAP Kinase Signaling System; Mice; Morpholines; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Proto-Oncogene Proteins c-akt; Sepsis; Thiocarbamates; Tumor Necrosis Factor-alpha | 2008 |
Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway.
Topics: Adenocarcinoma; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cell Movement; Chromones; Flavonoids; Focal Adhesion Kinase 1; Humans; Integrin alphaVbeta3; Lung Neoplasms; Morpholines; NF-kappa B; Oncogene Protein v-akt; Osteopontin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proline; Signal Transduction; Thiocarbamates; Tosylphenylalanyl Chloromethyl Ketone | 2009 |
Protection of capsaicin against hypoxia-reoxygenation-induced apoptosis of rat hippocampal neurons.
Topics: Animals; Apoptosis; Blotting, Western; Capsaicin; Caspase 3; Caspase Inhibitors; Cells, Cultured; Chromones; Enzyme Inhibitors; Hippocampus; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Indicators and Reagents; Morpholines; Neurons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiocarbamates | 2008 |
Involvement of 15-lipoxygenase in the inflammatory arthritis.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Chromones; Eicosapentaenoic Acid; Fibroblasts; Fluorenes; Humans; I-kappa B Kinase; Interleukin-1beta; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proline; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Messenger; RNA, Small Interfering; Synovial Membrane; Thiocarbamates; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2012 |
EphrinB/EphB forward signaling in Müller cells causes apoptosis of retinal ganglion cells by increasing tumor necrosis factor alpha production in rat experimental glaucomatous model.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Cells, Cultured; Chromones; Disease Models, Animal; Ephrin-B1; Excitatory Amino Acid Agents; Glaucoma; Glial Fibrillary Acidic Protein; Intercellular Signaling Peptides and Proteins; Male; Morpholines; Phenols; Piperidines; Proline; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Eph Family; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha | 2018 |
Hormesis of low-dose inhibition of pAkt1 (Ser473) followed by a great increase of proline-rich inositol polyphosphate 5-phosphatase (PIPP) level in oocytes.
Topics: Animals; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Shape; Chromones; Down-Regulation; Hormesis; Inositol Polyphosphate 5-Phosphatases; Meiotic Prophase I; Mice; Morpholines; Oocytes; Phosphatidylinositol Phosphates; Phosphorylation; Proline; Protein Kinase C-delta; Proto-Oncogene Proteins c-akt; Up-Regulation | 2021 |