Page last updated: 2024-08-18

proflavine and acridines

proflavine has been researched along with acridines in 201 studies

Research

Studies (201)

TimeframeStudies, this research(%)All Research%
pre-1990183 (91.04)18.7374
1990's9 (4.48)18.2507
2000's5 (2.49)29.6817
2010's3 (1.49)24.3611
2020's1 (0.50)2.80

Authors

AuthorsStudies
Jenkins, TC; McConnaughie, AW1
Antonini, I; Jenkins, TC; Kelland, LR; Martelli, S; Mazerski, J; Menta, E; Pescalli, N; Polucci, P; Stefanska, B1
Calberg-Bacq, CM; Cannistraro, S; Van de Vorst, A1
Lion, Y; Saucin, M; van de Vorst, A2
Cannistraro, S; van de Vorst, A1
Speit, G; Vogel, W1
Brodthagen, H; Genner, J; Veien, NK; Wettermark, G2
Calberg-Bacq, CM; Piette, J; Van de Vorst, A8
Piette, J1
Neidle, S1
Burleson, GR; Caulfield, MJ; Pollard, M1
Lion, Y; Van de Vorst, A1
Gräslund, A; Rupprecht, A; Ström, G1
Chisholm, I; Jones, BR; O'Day, DM; Pilley, S; Poirier, R; Rice, NS; Steele, A1
Leng, M; Ranstein, J1
Jarrat, M; Knox, J1
Calberg-Bacq, CM; Piette, J; Siquet-Descans, F; Van de Vorst, A1
Jarrat, M1
Berliner, LJ; Shen, YY1
Hara, J; Kinoshita, S; Manabe, R; Ohashi, Y; Sato, K; Tano, Y1
Rapp, F; Verwoerd, DW1
Adam, E; Kaufman, RH; Melnick, JL; Mirkovic, RR; Young, RL1
Moscona, AA; Wiens, AW1
Nairn, JA; Pearlstein, RM; Van Nostrand, F1
Canuel, LL; Patel, DJ1
Martin, RF1
Buchanan, JD; Davies, JV; Phillips, GO; Power, DM1
Calberg-Bacq, CM; Cannistraro, S; Piette, J; Van de Vorst, A1
Cabrera-Juárez, E; Sánchez-Rincón, DA1
Gutberlet, RL; Snyder, MJ; Wald, ER1
Mattick, JS1
Kushner, DJ; McKellar, RC1
Chao, L1
Koleva, P; Todorov, T1
Hiromi, K; Inouye, K; Tonomura, B1
Arnaboldi, A; Bianchi, A; Daffara, P; Santamaria, L1
Reddy, BS; Sakore, TD; Seshadri, TP; Sobell, HM1
Bloomfield, VA; Riemer, SC1
Matzke, KH; Thiessen, G; Tiffe, HW1
Crothers, DM; Dattagupta, N; Hogan, M1
Kamiya, M1
Alden, CJ; Arnott, S1
Calberg-Bacq, CM; Piette, J; Siquet-Descans, F1
Patel, DJ1
Ramstein, J1
Goswami, DN1
Politova, ZKh; Shraer, DP1
Bello, LJ; Madore, HP1
Neidle, S; Sanderson, M; Taylor, G1
Fahrig, R1
Kushner, KJ; McKellar, RC; McKenzie, CN1
Crothers, DM; Müller, W1
MacNaughton, AW; Winder, FG1
Papaphilis, AD; Shaw, YH1
Niemann, M; Schumm, DE; Webb, TE; Yannarell, A1
Kubota, Y; Steiner, RF1
Regan, JD; Setlow, RB1
Fujisaki, Y; Fujita, K; Hashimoto, K; Kubota, Y; Miyanohana, E; Wakita, M1
Achari, A; Berman, HM; Carrell, HL; Glusker, JP; Neidle, S; Stallings, WC; Taylor, GL1
Little, JB; Williams, JR1
Ohno, M; Saruwatari, J; Watanabe, M1
Khatenever, ML; Shraer, DP1
Böhner, R; Hagen, U1
Dourlent, M; Hogrel, JF2
Cory, JG; Girgenti, AJ; Whitford, TW1
Poletayev, AI1
Dolder, R; Selkirk, AB1
Kallenbach, NR; Leng, M; Ramstein, J1
Badea, MG; Georghiou, S1
Bloomfield, VA; McCall, PJ2
Brantner, JH; McRorie, RA; Medicus, RG1
Minchenkova, LE; Poletayev, AI; Zavriev, SK1
Maenhaut-Michel, G1
Mookerjee, A; Mukhopadhyay, R1
Doherty, NR; Taylor, PK1
Capomacchia, AC; Naik, DV; Roy, T; Schulman, SG1
Benkert, B; Garbrecht, M; Mertelsmann, R; Neth, R1
Whillans, DW1
Bial'skaia, EB; Ratgauz, GL; Shraer, DP1
Chiha, PA; Clarke, RH; Stratton, RD1
Holbrook, DJ; Washington, ME; Wichard, LP1
Blagoveshchenskiĭ, VA; Shraer, DP1
Clark, S; Jost, E1
Co, T; Maki, AH1
Baguley, BC; Ferguson, LR; Iwamoto, Y; Pearson, A1
Adelstein, SJ; Kassis, AI; Kinsey, BM; Little, JB; Whaley, JM1
Jeffery, J; Laptook, AR; Rosenfeld, CR1
Adelstein, SJ; Fayad, F; Kassis, AI; Kinsey, BM; Venkateshan, CN1
Harbison, GS; Juang, CL; Tang, P1
Revich, GG; Ripley, LS1
Vela, JA1
Gniazdowski, M1
Kovács, A; Kovács-Hadady, K1
Goh, CL3
Denny, WA; Feigon, J; Ferguson, LR1
Kumar, HD; Tripathi, AK1
Berman, HM; Herzyk, P; Neidle, S; Pearl, LH1
Hosur, MV; Sundaralingam, M; Westhof, E1
Galley, WC; Lee, WE1
Brock, KH; DeMarini, DM; Doerr, CL; Moore, MM1
Chassignol, M; Decout, JL; Habhoub, N; Hélène, C; Le Doan, T; Lhomme, J; Praseuth, D; Thuong, NT1
Uggla, AH1
Leng, M; Malinge, JM1
Clark, A; Ripley, LS1
Decout, JL; Habhoub, N; Hélène, C; Le Doan, T; Lhomme, J; Perrouault, L; Praseuth, D; Thuong, NT1
Corin, AF; Jovin, TM1
Genest, D; Kearns, DR; Mirau, PA1
Aggarwal, AK; Neidle, S1
Andreoni, L; Arnaboldi, A; Bianchi, A; Daffara, P; Santamaria, L1
Roels, H; Van amme, D1
Hiatt, CW1
Gravelle, MJ; Kushner, DJ; Mehta, BM1
Moore, PD; Piette, J1
Calberg-Bacq, CM; Lopez, M; Piette, J; van de Vorst, A2
Hutchinson, F; Skopek, TR1
Calberg-Bacq, CM; Decuyper, J; Lion, Y; Machiroux, R; Piette, J; Van de Vorst, A1
Bhandary, KK; Gabbay, EJ; King, D; Sakore, TD; Sobell, HM1
Bhandary, KK; Sakore, TD; Sobell, HM1
Clementi, E; Corongiu, G; Kim, KS1
Berman, HM; Beveridge, DL; Finney, JL; Goodfellow, JM; Mezei, M; Neidle, S1
Sundaralingam, M; Westhof, E2
Antonini, E; Ascenzi, P; Bolognesi, M; Guarneri, M; Menegatti, E1
Austin, EB; Baldwin, RW; Holmes, CH; Robins, RA1
Ford, JL; Hunt, PB1
Carin, M; Nielsen, OF; Westergaard, O1
Fenton, JW; Sonder, SA1
Andrich, MP; Golden, SM1
Aggarwal, A; Islam, SA; Kuroda, R; Neidle, S1
Baguley, BC; Denny, WA; Ferguson, LR1
Ehrenberg, M; Ramstein, J; Rigler, R1
Grimm, K1
Hashimoto, GM; Loew, GH; Pack, GR1
Dearing, A; Kollman, PA; Weiner, PK1
Rosenkranz, HS; Speck, WT1
Cozzani, I; Jori, G1
Mennigmann, HD; Müller, W1
Horton, HR; Kaminski, EA1
Back, KC; Rogers, AM1
Dearing, A; Kollman, PA; Weiner, P1
Roberts, JE2
Berman, HM; Dabrow, M; Neidle, S; Shieh, HS1
Berman, HM; Neidle, S; Shieh, HS1
Rao, ST; Sundaralingam, M; Westhof, E1
Gniazdowski, M; Piestrzeniewicz, MK; Szemraj, J1
PEACOCKE, AR1
SATYANARAYANAMURTHI, GV1
DENES, G; KRAMER, M; POLGAR, L1
DULBECCO, R; VOGT, M1
BARNETT, L; BENZER, S; BRENNER, S1
FRANKLIN, RM1
THORNLEY, MJ; YUDKIN, J2
SINAI, J; YUDKIN, J2
BROWN, F; STEWART, DL1
SLUYTERMAN, LA1
GINSBERG, HS; WILCOX, WC1
LABZOFFSKY, NA; LESIAK, J; ZALAN, E1
GREENBERG, J; WOODY-KARRER, P1
CHAMBRON, J; DAUNE, M; SADRON, C1
GROS, F; SOFFER, RL1
ROTT, R; SCHOLTISSEK, C1
LABZOFFSKY, NA; ZALAN, E1
BUBEL, HC; WOLFF, DA1
HARTMANN, G; LIERSCH, M1
SCHOLTISSEK, C1
HIATT, CW; KAUFMAN, E1
KAY, D1
ROBBINS, E1
NESSEL, E; SCHUEMMELFEDER, N; WESSEL, W1
LERMAN, LS; LUZZATI, V; MASSON, F1
KETCHAM, AS; NASH, SC; SMITH, RR1
BRIODY, BA; STANNARD, C1
DEAN, AC; HINSHELWOOD, C1
BASKETT, AC1
Gehlen, MH; Pereira, RV1
Inbar, P; Yang, J1
Boyer, G; Delmas, F; Di Giorgio, C; Galy, JP; Shimi, K1
Fedorocko, P; Imrich, J; Janovec, L; Koval', J; Kozurková, M; Kristian, P; Mikes, J; Sabolová, D; Stefanisinová, M; Ungvarský, J1
Allegro, D; Benchabane, Y; Boyer, G; De Méo, M; Di Giorgio, C; Peyrot, V; Sabatier, AS1
Basu, S; Chakraborty, B; Dasgupta, S; Roy, AS1
Cižeková, L; Grolmusová, A; Hunáková, L; Imrich, J; Ipóthová, Z; Janovec, L; Labudová, M; Paulíková, H1
Kožurková, M; Kristian, P; Sabolová, D1
Chen, J; Jia, M; Jia, Y; Pan, H; Sun, Z; Wang, X; Zhou, J1

Reviews

5 review(s) available for proflavine and acridines

ArticleYear
The molecular basis for the action of some DNA-binding drugs.
    Progress in medicinal chemistry, 1979, Volume: 16

    Topics: Acridines; Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Dactinomycin; Daunorubicin; DNA; Ellipticines; Ethidium; Intercalating Agents; Lucanthone; Models, Chemical; Proflavine

1979
[The photodynamic effect in Herpes simplex: a review].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1975, Volume: 26, Issue:7

    Topics: Acridines; Animals; Antibodies, Viral; Candida albicans; Carcinogens; Cell Transformation, Neoplastic; Cytopathogenic Effect, Viral; Defective Viruses; Fungicides, Industrial; Guinea Pigs; Herpes Simplex; Humans; Light; Phenazines; Photosensitivity Disorders; Proflavine; Simplexvirus; Trichophyton

1975
[Molecular mechanisms of inhibition of RNA synthesis. DNA-interacting inhibitors].
    Postepy biochemii, 1985, Volume: 31, Issue:1

    Topics: Acridines; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; DNA; DNA, Bacterial; Escherichia coli; Humans; In Vitro Techniques; Intercalating Agents; Ligands; Nucleic Acid Synthesis Inhibitors; Proflavine; RNA

1985
Proflavine, proflavine dihydrochloride, proflavine hemisulphate and proflavine monohydrochloride.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1980, Volume: 24

    Topics: Acridines; Animals; Chemical Phenomena; Chemistry; Humans; Mice; Mutagenicity Tests; Neoplasms, Experimental; Proflavine; Rats; Sister Chromatid Exchange; Terminology as Topic

1980
A review on acridinylthioureas and its derivatives: biological and cytotoxic activity.
    Journal of applied toxicology : JAT, 2017, Volume: 37, Issue:10

    Topics: Acridines; Antineoplastic Agents; Cell Line, Tumor; DNA Damage; Humans; Isothiocyanates; Proflavine; Structure-Activity Relationship; Thiourea

2017

Trials

3 trial(s) available for proflavine and acridines

ArticleYear
Photodynamic inactivation of verrucae vulgares. II.
    Acta dermato-venereologica, 1977, Volume: 57, Issue:5

    Topics: Acridines; Adolescent; Adult; Child; Clinical Trials as Topic; Dimethyl Sulfoxide; Double-Blind Method; Evaluation Studies as Topic; Female; Humans; Male; Neutral Red; Phenazines; Photochemotherapy; Placebos; Proflavine; Warts

1977
Treatment of genital herpes simplex virus infection with photodynamic inactivation.
    American journal of obstetrics and gynecology, 1978, Dec-15, Volume: 132, Issue:8

    Topics: Acridines; Clinical Trials as Topic; Female; Herpes Simplex; Humans; Phototherapy; Placebos; Proflavine; Recurrence; Simplexvirus; Time Factors; Uterine Cervical Diseases; Vulvar Diseases

1978
Comparison of the treatment of herpes genitalis in men with proflavine photoinactivation, idoxuridine ointment, and normal saline.
    The British journal of venereal diseases, 1975, Volume: 51, Issue:2

    Topics: Acridines; Clinical Trials as Topic; Complement Fixation Tests; Evaluation Studies as Topic; Genital Diseases, Male; Herpes Simplex; Humans; Idoxuridine; Male; Ointments; Phototherapy; Proflavine; Recurrence; Sodium Chloride

1975

Other Studies

193 other study(ies) available for proflavine and acridines

ArticleYear
Novel acridine-triazenes as prototype combilexins: synthesis, DNA binding, and biological activity.
    Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

    Topics: Acridines; Animals; Antineoplastic Agents; Base Sequence; Cattle; Diminazene; DNA; Drug Design; Humans; Models, Molecular; Molecular Sequence Data; Thymus Gland; Triazenes; Tumor Cells, Cultured

1995
1-[(omega-aminoalkyl)amino]-4-[N-(omega-aminoalkyl)carbamoyl]-9-oxo-9, 10-dihydroacridines as intercalating cytotoxic agents: synthesis, DNA binding, and biological evaluation.
    Journal of medicinal chemistry, 1997, Nov-07, Volume: 40, Issue:23

    Topics: Acridines; Animals; Antineoplastic Agents; Cattle; DNA; Drug Screening Assays, Antitumor; Humans; Intercalating Agents; Mice; Nucleic Acid Denaturation; Spectrometry, Fluorescence; Tumor Cells, Cultured

1997
Photosensitizing efficiency of proflavine bound to polyadenylic acid as studied by EPR.
    Photochemistry and photobiology, 1976, Volume: 23, Issue:2

    Topics: Acridines; Binding Sites; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Photochemistry; Poly A; Proflavine

1976
[Photosensitization of consitutents of nucleic acids by proflavine. Mechanism of formation of hydrogen addition radicals in frozen aquenous solutions (author's transl)].
    Biochimica et biophysica acta, 1976, Jun-08, Volume: 430, Issue:3

    Topics: Acridines; Binding Sites; Deoxyribonucleotides; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Hydrogen-Ion Concentration; Molecular Conformation; Nucleic Acid Conformation; Photochemistry; Proflavine; Water

1976
[Hydrogen-adduct radicals in thymidine and thymidine 5'-monophosphate photosensitized by proflavin. Protection by sulfur compounds (author's transl)].
    Biochimica et biophysica acta, 1977, Jan-20, Volume: 474, Issue:2

    Topics: Acridines; Chemical Phenomena; Chemistry; Disulfides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Molecular Conformation; Photochemistry; Proflavine; Sulfhydryl Compounds; Thymidine; Thymine Nucleotides

1977
The effect on sister-chromatid exchanges of drugs and dyes by intercalation and photoactivation.
    Mutation research, 1979, Volume: 59, Issue:2

    Topics: Acridines; Animals; Antipsychotic Agents; Cell Line; Chlorpromazine; Chlorprothixene; Chromosome Aberrations; Chromosomes; Coloring Agents; Cricetinae; Crossing Over, Genetic; Dose-Response Relationship, Drug; Light; Methylene Blue; Proflavine; Promazine

1979
Photodynamic inactivation of verrucae vulgares. I.
    Acta dermato-venereologica, 1977, Volume: 57, Issue:5

    Topics: Acridines; Dimethyl Sulfoxide; Humans; Microscopy, Fluorescence; Neutral Red; Phenazines; Photochemotherapy; Proflavine; Skin; Staining and Labeling; Warts

1977
[Alteration of guanine residues during DNA photosensitization by proflavin (proceedings)].
    Archives internationales de physiologie et de biochimie, 1979, Volume: 87, Issue:3

    Topics: Acridines; Bacteriophage phi X 174; DNA, Viral; Guanine; Proflavine; Ultraviolet Rays

1979
Guanine alteration and production of strand breaks in DNA photosensitized by proflavine [proceedings].
    Archives internationales de physiologie et de biochimie, 1979, Volume: 87, Issue:5

    Topics: Acridines; DNA; DNA, Single-Stranded; DNA, Superhelical; Guanine; Light; Proflavine; Ultraviolet Rays

1979
Ozonation of mutagenic and carcinogenic polyaromatic amines and polyaromatic hydrocarbons in water.
    Cancer research, 1979, Volume: 39, Issue:6 Pt 1

    Topics: 2-Naphthylamine; 9,10-Dimethyl-1,2-benzanthracene; Acridines; Acriflavine; Amines; Animals; Carcinogens, Environmental; Croton Oil; Drug Evaluation, Preclinical; Female; Male; Methylcholanthrene; Mice; Mutagens; Neoplasms, Experimental; Ozone; Polycyclic Compounds; Proflavine; Water Pollutants; Water Pollutants, Chemical; Water Supply

1979
Production of breaks in single- and double-stranded forms of bacteriophage phi X174 DNA by proflavine and light treatment.
    Photochemistry and photobiology, 1979, Volume: 30, Issue:3

    Topics: Acridines; Bacteriophage phi X 174; Centrifugation, Density Gradient; DNA; DNA, Single-Stranded; Escherichia coli; Light; Proflavine

1979
Electron transfer in photosensitization of biomolecules by acridine dyes.
    Photochemistry and photobiology, 1975, Volume: 21, Issue:2

    Topics: Acridines; Electron Spin Resonance Spectroscopy; Electron Transport; Molecular Conformation; Photochemistry; Proflavine; Radiation Effects; Ultraviolet Rays

1975
Light-induced free radicals in oriented DNA-proflavine complexes.
    Photochemistry and photobiology, 1975, Volume: 21, Issue:3

    Topics: Acridines; Chemical Phenomena; Chemistry; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Light; Proflavine

1975
Proflavine photodynamic viral inactivation in herpes simplex keratitis.
    American journal of ophthalmology, 1975, Volume: 79, Issue:6

    Topics: Acridines; Adult; Anterior Chamber; Betamethasone; Edema; Female; Humans; Idoxuridine; Keratitis, Dendritic; Male; Middle Aged; Phototherapy; Prednisolone; Prednisone; Proflavine; Recurrence; Simplexvirus; Suppuration; Wound Healing

1975
Effect of DNA base composition on the intercalation of proflavine. A kinetic study.
    Biophysical chemistry, 1975, Volume: 3, Issue:3

    Topics: Acridines; Animals; Base Sequence; Binding Sites; Cattle; DNA; DNA, Bacterial; Electron Spin Resonance Spectroscopy; Kinetics; Methylation; Micrococcus; Proflavine; Species Specificity; Temperature; Thermodynamics; Thymus Gland

1975
Triplet state population study in relation to the aggregation of proflavine in frozen solutions.
    Radiation and environmental biophysics, 1975, Dec-04, Volume: 12, Issue:4

    Topics: Acridines; Electron Spin Resonance Spectroscopy; Freezing; Proflavine; Solutions; Water

1975
Free radical induction in bacteriophage phiX174 DNA after exposure to proflavine and visible light.
    Biochimica et biophysica acta, 1977, Aug-02, Volume: 477, Issue:3

    Topics: Acridines; Binding Sites; Coliphages; DNA; DNA, Viral; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Kinetics; Light; Proflavine

1977
Photodynamic inactivation of Herpes simplex virus.
    Photochemistry and photobiology, 1977, Volume: 25, Issue:4

    Topics: Acridines; Coloring Agents; Light; Photochemistry; Proflavine; Simplexvirus; Virus Replication

1977
Physical evidence for an apolar binding site near the catalytic center of human alpha-thrombin.
    Biochemistry, 1977, Oct-18, Volume: 16, Issue:21

    Topics: Acridines; Binding Sites; Electron Spin Resonance Spectroscopy; Humans; Indoles; Kinetics; Proflavine; Protein Binding; Spectrophotometry; Spin Labels; Thrombin

1977
[Photodynamic inactivation of herpes simplex virus: II. Photodynamic inactivation with proflavine in experimental herpetic keratitis (author's transl)].
    Nippon Ganka Gakkai zasshi, 1977, Sep-10, Volume: 81, Issue:9

    Topics: Acridines; Animals; Keratitis, Dendritic; Phototherapy; Proflavine; Rabbits; Simplexvirus

1977
Biochemical transformation of mouse cells by herpes simplex virus type 2: enhancement by means of low-level photodynamic treatment.
    Journal of virology, 1978, Volume: 26, Issue:1

    Topics: Acridines; Cell Line; Cell Transformation, Viral; DNA; DNA, Viral; Light; Proflavine; Simplexvirus

1978
Proflavine photosensitization of double and single stranded DNA: EPR study of the effect of various sulphur-containing substances.
    Photochemistry and photobiology, 1978, Volume: 27, Issue:4

    Topics: Acridines; DNA; DNA, Single-Stranded; Drug Interactions; Electron Spin Resonance Spectroscopy; Light; Proflavine; Sulfur

1978
Influence of the DNA structure on the free radical induction due to proflavine and light treatment.
    Radiation and environmental biophysics, 1979, Apr-30, Volume: 16, Issue:2

    Topics: Acridines; Animals; Bacteriophages; Cattle; Chemical Phenomena; Chemistry; DNA; DNA, Bacterial; DNA, Circular; DNA, Single-Stranded; DNA, Viral; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Light; Photochemistry; Proflavine; Thymus Gland

1979
Proflavine as a differential probe of gene expression: inhibition of glutamine synthetase induction in embryonic retina.
    Developmental biology, 1975, Volume: 44, Issue:1

    Topics: Acridines; Amino Acids; Animals; Antibodies; Carbon Radioisotopes; Chick Embryo; Cytoplasm; Depression, Chemical; DNA; Enzyme Induction; Glutamate-Ammonia Ligase; Hydrocortisone; Proflavine; Retina; RNA; Thymidine; Transcription, Genetic; Tritium; Uridine

1975
Time dependence of triplet-singlet excitation transfer from compact poly rA to bound dye at 77 K.
    Biophysical journal, 1979, Volume: 26, Issue:1

    Topics: Acridines; Ethidium; Freezing; Kinetics; Luminescence; Mathematics; Nucleic Acid Conformation; Poly A; Proflavine

1979
Sequence specificity of mutagen-nucleic acid complexes in solution: intercalation and mutagen-base pair overlap geometries for proflavine binding to dC-dC-dG-dG and dG-dG-dC-dC self-complementary duplexes.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:7

    Topics: Acridines; Base Sequence; Binding Sites; Magnetic Resonance Spectroscopy; Mutagens; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Proflavine; Temperature

1977
Induction of double-stranded breaks in DNA by binding with an 125i-labelled acridine.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1977, Volume: 32, Issue:5

    Topics: Acridines; DNA, Viral; Electrons; Electrophoresis, Agar Gel; Iodine Radioisotopes; Microscopy, Electron; Proflavine; Radiation Tolerance

1977
Interaction of aminoacridines with nucleic acids. A pulse-radiolysis study.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1978, Volume: 33, Issue:6

    Topics: Acridines; Chemical Phenomena; Chemistry; Coloring Agents; DNA; Proflavine; Pulse Radiolysis; RNA

1978
Photodynamic activity of dyes with different DNA binding properties I. free-radical induction in DNA.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1978, Volume: 34, Issue:3

    Topics: Acridines; Binding Sites; Chloroquine; Coloring Agents; DNA; Ethidium; Free Radicals; Light; Proflavine; Pyronine; Quinacrine; Thioxanthenes

1978
Photodynamic activity of dyes with different DNA binding properties II. T4 phage inactivation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1978, Volume: 34, Issue:3

    Topics: Acridines; Binding Sites; Chloroquine; Coliphages; Coloring Agents; DNA, Viral; Ethidium; Light; Proflavine; Pyronine; Quinacrine; Thioxanthenes

1978
Features of the damage produced by proflavine on transforming deoxyribonucleic acid.
    Journal of bacteriology, 1979, Volume: 137, Issue:3

    Topics: Acridines; DNA, Bacterial; Haemophilus influenzae; Nucleic Acid Denaturation; Proflavine; Sodium Chloride; Temperature; Transformation, Bacterial

1979
Group B beta-hemolytic streptococcal colonization. Acquisition, persistence, and effect of umbilical cord treatment with triple dye.
    American journal of diseases of children (1960), 1977, Volume: 131, Issue:2

    Topics: Acridines; Age Factors; Coloring Agents; Drug Combinations; Gentian Violet; Hexachlorophene; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Maryland; Pharynx; Proflavine; Quaternary Ammonium Compounds; Rectum; Streptococcal Infections; Streptococcus agalactiae; Umbilical Cord

1977
Comparative studies of the effects of acridines and other petite inducing drugs on the mitochondrial genome of Saccharomyces cerevisiae.
    Molecular & general genetics : MGG, 1977, Apr-29, Volume: 152, Issue:3

    Topics: Acridines; Depression, Chemical; DNA Replication; DNA, Mitochondrial; Extrachromosomal Inheritance; Mutation; Proflavine; Saccharomyces cerevisiae

1977
The effect of proflavine on pyruvate kinase I of Escherichia coli B.
    Canadian journal of biochemistry, 1977, Volume: 55, Issue:6

    Topics: Acridines; Allosteric Regulation; Biological Transport; Carbohydrate Epimerases; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Lyases; Methylglucosides; Phosphotransferases; Proflavine; Pyruvate Kinase; Species Specificity

1977
Regulation of RNA polymerase subunit synthesis in Escherichia coli: utilization of DNA-Intercalating drugs as a probe.
    Archives of biochemistry and biophysics, 1977, Volume: 183, Issue:1

    Topics: Acridines; Bacterial Proteins; Berberine; Berberine Alkaloids; Dactinomycin; DNA-Directed RNA Polymerases; Escherichia coli; Ethidium; Peptide Fragments; Proflavine; Rifampin; RNA, Bacterial; RNA, Messenger; Uridine

1977
[Elimination of multiple drug resistance of intestinal bacteria in white mice in vivo with proflavine and rimactan].
    Veterinarno-meditsinski nauki, 1978, Volume: 15, Issue:3

    Topics: Acridines; Animals; Anti-Bacterial Agents; Depression, Chemical; Drug Resistance, Microbial; Escherichia coli; Intestines; Mice; Proflavine; Proteus; Rifamycins; Salmonella Infections, Animal

1978
Photodynamic effect of proflavine on phiX174 bacteriophage, its DNA replicative form and its isolated single-stranded DNA: inactivation, mutagenesis and repair.
    Molecular & general genetics : MGG, 1978, Nov-16, Volume: 167, Issue:1

    Topics: Acridines; Coliphages; DNA Repair; DNA Replication; DNA, Single-Stranded; Escherichia coli; Mutation; Proflavine

1978
Interaction of alpha-chymotrypsin and a protein proteinase inhibitor, Streptomyces subtilisin inhibitor. The formation of ternary complex of Streptomyces subtilisin inhibitor, alpha-chymotrypsin, and proflavine.
    Journal of biochemistry, 1979, Volume: 85, Issue:2

    Topics: Acridines; Chymotrypsin; Kinetics; Proflavine; Protease Inhibitors; Protein Binding; Spectrophotometry; Streptomyces; Subtilisins

1979
Photocarcinogenesis by methoxypsoralen, neutral red and proflavine.
    Bollettino chimico farmaceutico, 1979, Volume: 118, Issue:7

    Topics: Acridines; Animals; Breast Neoplasms; Female; Methoxsalen; Mice; Neoplasms; Neutral Red; Phenazines; Proflavine; Sebaceous Gland Neoplasms; Skin; Thyroid Neoplasms; Ultraviolet Rays

1979
Visualization of drug--nucleic acid interactions at atomic resolution. V. Structure of two aminoacridine--dinucleoside monophosphate crystalline complexes, proflavine--5-iodocytidylyl (3'-5') guanosine and acridine orange--5-iodocytidylyl (3'-5') guanosin
    Journal of molecular biology, 1979, Dec-25, Volume: 135, Issue:4

    Topics: Acridine Orange; Acridines; Binding Sites; Crystallography; Guanosine; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Proflavine

1979
Effect of Mg++ and polyamines on proflavine binding to T2 DNA.
    Biopolymers, 1979, Volume: 18, Issue:7

    Topics: Acridines; Binding Sites; DNA, Viral; Magnesium; Polyamines; Proflavine; T-Phages

1979
The acridine dyes: their purification, physiochemical, and cytochemical properties. II. Purification of acriflavine and proflavine and their cytochemical behaviour regarding machine-oriented evaluation.
    Histochemistry, 1977, Jul-18, Volume: 53, Issue:1

    Topics: Acridines; Acriflavine; Animals; Autoanalysis; Chickens; Chromatography; DNA; Erythrocytes; Photochemistry; Proflavine; Spectrometry, Fluorescence

1977
Transient electric dichroism studies of the structure of the DNA complex with intercalated drugs.
    Biochemistry, 1979, Jan-23, Volume: 18, Issue:2

    Topics: Acridines; Animals; Cattle; Chemical Phenomena; Chemistry; Dactinomycin; DNA; Ethidium; Nucleic Acid Conformation; Proflavine; Spectrometry, Fluorescence; Spectrophotometry; Thymus Gland

1979
The induced circular dichroism of proflavine intercalated to DNA. Dye-polymer exciton interactions.
    Biochimica et biophysica acta, 1979, Mar-28, Volume: 562, Issue:1

    Topics: Acridines; Animals; Cattle; Chemical Phenomena; Chemistry; Circular Dichroism; DNA; Models, Chemical; Nucleic Acid Conformation; Osmolar Concentration; Proflavine

1979
Stereochemical model for proflavin intercalation in A-DNA.
    Nucleic acids research, 1977, Volume: 4, Issue:11

    Topics: Acridines; DNA; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Proflavine

1977
Proflavine mediated photoinactivation of bacteriophage phiX174 and its isolated DNA: effects of agents modifying various photochemical pathways.
    Photochemistry and photobiology, 1977, Volume: 26, Issue:4

    Topics: Acridines; Coliphages; DNA, Viral; Light; Photochemistry; Proflavine

1977
Photodynamic effects of proflavin on bacteriophage phi x 174 and its isolated DNA.
    Photochemistry and photobiology, 1977, Volume: 26, Issue:6

    Topics: Acridines; Coliphages; DNA, Viral; Light; Proflavine

1977
Mutagen-nucleic acid complexes at the polynucleotide duplex level in solution: intercalation of proflavine into poly(dA-dT) and the melting transition of the complex.
    Biopolymers, 1977, Volume: 16, Issue:12

    Topics: Acridines; Chemical Phenomena; Chemistry; Mutagens; Nucleic Acid Denaturation; Poly dA-dT; Polydeoxyribonucleotides; Proflavine; Temperature

1977
Proflavine as a probe of the interaction between oligopeptides and nucleic acids.
    Biochimie, 1977, Volume: 59, Issue:10

    Topics: Acridines; Chemical Phenomena; Chemistry; DNA; Oligopeptides; Poly A-U; Proflavine; Protein Binding; Spectrophotometry

1977
Dielectric behaviour of DNA-dye complexes.
    Indian journal of biochemistry & biophysics, 1977, Volume: 14, Issue:4

    Topics: Acridines; DNA; Electric Conductivity; Ethidium; Nucleic Acid Conformation; Nucleic Acid Denaturation; Proflavine; Temperature

1977
[Elimination of penicillinase plasmids by the new acridine derivative, Dimer].
    Antibiotiki, 1978, Volume: 23, Issue:5

    Topics: Acridines; Acriflavine; beta-Lactamase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Plasmids; Proflavine; Quinacrine; Staphylococcus aureus

1978
Stabilization of adenovirus nuclear RNA by intercalating drugs.
    Biochimica et biophysica acta, 1978, Sep-27, Volume: 520, Issue:2

    Topics: Acridines; Adenoviruses, Human; Cell Line; Chemical Phenomena; Chemistry; Daunorubicin; Drug Stability; Ethidium; Kinetics; Proflavine; RNA, Viral

1978
A 1:2 crystalline complex of ApA:proflavine: a model for binding to single-stranded regions in RNA.
    Nucleic acids research, 1978, Volume: 5, Issue:11

    Topics: Acridines; Adenine Nucleotides; Adenosine; Crystallization; Models, Biological; Models, Molecular; Nucleic Acid Conformation; Proflavine; RNA; X-Ray Diffraction

1978
The effect of dose and time on the induction of genetic alterations in Saccharomyces cerevisiae by aminoacridines in the presence and absence of visible light irradiation in comparison with the dose-effect-curves of mutagens with other type of action.
    Molecular & general genetics : MGG, 1976, Mar-22, Volume: 144, Issue:2

    Topics: Acridines; Dose-Response Relationship, Drug; Genetic Code; Light; Mutation; Proflavine; Recombination, Genetic; Saccharomyces cerevisiae; Time Factors; Transcription, Genetic

1976
Correlation of resistance to proflavine and penicillin in Escherichia coli.
    Antimicrobial agents and chemotherapy, 1976, Volume: 10, Issue:4

    Topics: Acridines; Anti-Bacterial Agents; Escherichia coli; Penicillin Resistance; Penicillins; Permeability; Proflavine

1976
Interactions of heteroaromatic compounds with nucleic acids. 1. The influence of heteroatoms and polarizability on the base specificity of intercalating ligands.
    European journal of biochemistry, 1975, Volume: 54, Issue:1

    Topics: Acridines; Animals; Bacillus subtilis; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Dialysis; DNA; DNA, Bacterial; Escherichia coli; Ligands; Mathematics; Methylation; Micrococcus; Proflavine; Structure-Activity Relationship; Thymus Gland

1975
Increased DNA polymerase and ATP-dependent deoxyribonuclease activities following DNA damages in mycobacterium smegmatis.
    Molecular & general genetics : MGG, 1977, Feb-15, Volume: 150, Issue:3

    Topics: Acridines; Adenosine Triphosphate; Bacterial Proteins; Caffeine; Deoxyribonucleases; DNA-Directed DNA Polymerase; DNA, Bacterial; Ethidium; Ethyl Methanesulfonate; Fluorouracil; Mechlorethamine; Methyl Methanesulfonate; Mitomycins; Mutation; Mycobacterium; Nalidixic Acid; Proflavine; Ultraviolet Rays

1977
Interaction of acridines and tetrahydroacridines with DNA at low DNA/dye ratios.
    Biochimica et biophysica acta, 1977, May-17, Volume: 476, Issue:2

    Topics: Acridines; Animals; Cattle; Chemical Phenomena; Chemistry; DNA; Kinetics; Ligands; Proflavine; Tacrine; Thymus Gland

1977
Proflavine sensitivity of RNA processing in isolated nuclei.
    Nucleic acids research, 1977, Volume: 4, Issue:3

    Topics: Acridines; Animals; Binding Sites; Biological Transport; Cell Nucleus; Cell-Free System; Chemical Phenomena; Chemistry; Cytoplasm; Liver; Liver Regeneration; Proflavine; Rats; RNA, Messenger; RNA, Ribosomal

1977
Fluorescence decay and quantum yield characteristics of acridine orange and proflavine bound to DNA.
    Biophysical chemistry, 1977, Volume: 6, Issue:3

    Topics: Acridines; Chemical Phenomena; Chemistry, Physical; DNA; Energy Transfer; Fluorescence; Poly C; Poly dA-dT; Poly G; Proflavine; Spectrometry, Fluorescence; Time Factors

1977
The effect of proflavine plus visible light of the DNA of human cells.
    Photochemistry and photobiology, 1977, Volume: 25, Issue:4

    Topics: Acridines; Cells, Cultured; Coloring Agents; DNA; Humans; Light; Proflavine

1977
Flow dichroism, flow polarized fluorescence and viscosity of the DNA acridine complexes.
    Biochimica et biophysica acta, 1977, Sep-06, Volume: 478, Issue:1

    Topics: Acridines; Chemical Phenomena; Chemistry; Circular Dichroism; DNA; Proflavine; Sonication; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Viscosity

1977
Structure of a dinucleoside phosphate--drug complex as model for nucleic acid--drug interaction.
    Nature, 1977, Sep-22, Volume: 269, Issue:5626

    Topics: Acridines; Hydrogen Bonding; Molecular Conformation; Nucleic Acid Conformation; Oligonucleotides; Proflavine; X-Ray Diffraction

1977
Selective protection of cultured human cells from the toxic effects of ultraviolet light by proflavine pretreatment.
    Radiation research, 1977, Volume: 72, Issue:1

    Topics: Acridines; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; In Vitro Techniques; Proflavine; Ultraviolet Rays

1977
Studies on papain catalysis with substrates containing the trans-p-phenylazobenzoyl group as a probe for hydrophobic interaction.
    Journal of biochemistry, 1977, Volume: 82, Issue:3

    Topics: Acridines; Arginine; Azo Compounds; Benzoates; Binding Sites; Catalysis; Dipeptides; Hydrolysis; In Vitro Techniques; Kinetics; Papain; Peptides; Proflavine; Substrate Specificity

1977
[Spontaneous mutants of S. aureus 209 P resistant to 3,6-diaminoacridines].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1977, Issue:8

    Topics: Acridines; Acriflavine; Bacteriophage Typing; Drug Resistance, Microbial; Mutation; Proflavine; Staphylococcus aureus

1977
Action of intercalating agents on the activity of DNA polymerase I.
    Biochimica et biophysica acta, 1977, Dec-02, Volume: 479, Issue:3

    Topics: Acridines; Binding, Competitive; Daunorubicin; DNA; DNA Polymerase I; DNA, Single-Stranded; Exonucleases; In Vitro Techniques; Kinetics; Nucleic Acid Synthesis Inhibitors; Proflavine; Quinacrine

1977
Influence of electric dichroism on the temperature-jump relaxation study of proflavine-DNA complexes.
    Biochemistry, 1976, Jan-27, Volume: 15, Issue:2

    Topics: Acridines; Animals; Binding Sites; Cattle; Circular Dichroism; DNA; Kinetics; Mathematics; Nucleic Acid Conformation; Proflavine; Spectrum Analysis; Temperature; Thymus Gland

1976
Inhibition of transfer ribonucleic acid nucleotidyl transferase (EC 2.7.7.25) from Ehrlich tumor cells by proflavine sulfate and ethidium bromide.
    Enzyme, 1976, Volume: 21, Issue:3

    Topics: Acridines; Adenosine Monophosphate; Animals; Anti-Bacterial Agents; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; Ethidium; Kinetics; Mice; Proflavine; RNA Nucleotidyltransferases

1976
Circular dichroism of flow-oriented DNA-proflavine complex.
    FEBS letters, 1976, Aug-15, Volume: 67, Issue:2

    Topics: Acridines; Binding Sites; Circular Dichroism; DNA, Bacterial; Mathematics; Nucleic Acid Conformation; Proflavine; Spectrophotometry; Spectrophotometry, Ultraviolet

1976
The influence of formulation on the percutaneous absorption of proflavine hemisulphate.
    Pharmaceutica acta Helvetiae, 1976, Volume: 51, Issue:6

    Topics: Acridines; Animals; Drug Compounding; Proflavine; Rats; Skin Absorption

1976
Binding isotherms and the interaction between proflavin and a DNA of high G-C content.
    Biophysical chemistry, 1976, Volume: 5, Issue:3

    Topics: Acridines; Binding Sites; Cytosine; DNA, Bacterial; Guanine; Macromolecular Substances; Mathematics; Micrococcus; Proflavine; Temperature; Thermodynamics

1976
Interaction between proflavine and guanosine 5'-phosphate: importance of photoexcitation.
    Photochemistry and photobiology, 1976, Volume: 24, Issue:5

    Topics: Acridines; Fluorescence; Guanine Nucleotides; Kinetics; Photochemistry; Proflavine; Temperature

1976
Kinetics of proflavin binding to bacteriophages T2L and T4D.
    Biopolymers, 1976, Volume: 15, Issue:12NA-NA-77

    Topics: Acridines; Coliphages; DNA, Viral; Kinetics; Proflavine; Protein Binding

1976
Fractionation of of proteolytic enzymes by affinity chromatography on sepharose aminocaproyl proflavin.
    Journal of chromatography, 1976, Dec-22, Volume: 129

    Topics: Acridines; Acrosin; Aminocaproates; Chromatography, Affinity; Peptide Hydrolases; Proflavine; Protein Binding; Resins, Synthetic; Sepharose; Serine

1976
Circular dichroism of DNA--proflavine, DNA--ethidium and DNA--distamycine flow--oriented complexes.
    Molecular biology reports, 1976, Volume: 3, Issue:2

    Topics: Acridines; Binding Sites; Circular Dichroism; Distamycins; DNA; Ethidium; Nucleic Acid Conformation; Proflavine; Pyrroles; Spectrophotometry, Ultraviolet

1976
Mechanisms of protection of gamma-irradiated bacteriophage lambda by proflavine.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1975, Volume: 27, Issue:5

    Topics: Acridines; Cobalt Radioisotopes; Coliphages; DNA Viruses; DNA, Viral; Dose-Response Relationship, Drug; Gamma Rays; Proflavine; Radiation Effects; Radiation-Protective Agents

1975
Effect of gamma-irradiation on dye-DNA binding.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1976, Volume: 30, Issue:6

    Topics: Acridines; Cobalt Radioisotopes; Coloring Agents; DNA; Gamma Rays; Proflavine

1976
Electronic spectra and electronic structures of some antimicrobials derived from proflavine.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:6

    Topics: Acridines; Chemical Phenomena; Chemistry; DNA; Molecular Conformation; Proflavine; Spectrometry, Fluorescence; Spectrophotometry, Atomic

1975
[The effect of actinomycin d, acridine dyes and related substances on the biosynthesis of nucleic acids in normal and leukemic white blood cells. Comparative investigation in intact cells and in a cell-free system (author's transl)].
    Klinische Wochenschrift, 1975, Aug-15, Volume: 53, Issue:16

    Topics: Acridines; Animals; Cell Membrane; Cell-Free System; Cells, Cultured; Dactinomycin; DNA; DNA-Directed RNA Polymerases; DNA, Neoplasm; Friend murine leukemia virus; Humans; Leukemia; Leukocytes; Mice; Nucleic Acids; Proflavine; RNA; RNA, Neoplasm; Subcellular Fractions; Thymidine; Tritium; Uridine

1975
Studies of electron migration in DNA in aqueous solution using intercalating dyes.
    Biochimica et biophysica acta, 1975, Dec-04, Volume: 414, Issue:2

    Topics: Acridines; Binding Sites; DNA; Electron Transport; Electrons; Ethidium; Free Radicals; Kinetics; Nucleic Acid Conformation; Proflavine; Spectrophotometry; Spectrophotometry, Ultraviolet

1975
[Specific and nonspecific factors that influence the transduction of genetic determinants for penicillinase activity and pathogenicity in Staphylococcus aureus. III. The prevention of the transduction of penicillinase determinants by acridine derivatives]
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1975, Volume: 0, Issue:9

    Topics: Acridines; Bacteriolysis; Depression, Chemical; Dose-Response Relationship, Drug; Genes; Penicillinase; Proflavine; Staphylococcus aureus; Transduction, Genetic

1975
Optically detected zero field magnetic resonance studies of proflavine-DNA and 3,4-benzpyrene-DNA complexes.
    Biochemical and biophysical research communications, 1975, Nov-03, Volume: 67, Issue:1

    Topics: Acridines; Benzopyrenes; Binding Sites; DNA; Magnetic Resonance Spectroscopy; Microwaves; Nucleic Acid Conformation; Proflavine

1975
Effect of nucleic-acid-binding compounds on the hydrolytic activity of various ribonucleases.
    European journal of biochemistry, 1975, Dec-15, Volume: 60, Issue:2

    Topics: Acridines; Aminoquinolines; Animals; Binding Sites; Cattle; Chloroquine; Ethidium; Kinetics; Pancreas; Primaquine; Proflavine; Protein Binding; Quinacrine; Ribonucleases; Spermidine; Spermine; Structure-Activity Relationship

1975
[The action of acridine derivatives on penicillinase production by staphylococcus aureus].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1975, Issue:11

    Topics: Acridines; Acriflavine; Depression, Chemical; Dose-Response Relationship, Drug; Penicillinase; Proflavine; Staphylococcus aureus

1975
Binding and arrangement of non-histone proteins in chromatin-like structures from mammalian cells.
    FEBS letters, 1975, Dec-01, Volume: 60, Issue:1

    Topics: Acridines; Binding Sites; Chromatin; Dactinomycin; Deoxyribonucleoproteins; DNA; Ethidium; Histones; Nucleic Acid Conformation; Nucleoproteins; Proflavine; Structure-Activity Relationship

1975
Competitive cooperative bindings of a small ligand to a linear polymer. II. Investigations on the mechanisms of proflavine binding to poly (A) and DNA.
    Biopolymers, 1976, Volume: 15, Issue:1

    Topics: Acridines; Binding Sites; Binding, Competitive; DNA; Models, Chemical; Poly A; Proflavine; Thermodynamics

1976
Binding of proflavin to T2L bacteriophage and its DNA.
    Biopolymers, 1976, Volume: 15, Issue:1

    Topics: Acridines; Binding Sites; Coliphages; DNA, Viral; Proflavine; Thermodynamics

1976
Study of triple-singlet energy transfer in an enzyme-dye complex using optical detection of magnetic resonance.
    Biochemistry, 1976, Mar-23, Volume: 15, Issue:6

    Topics: Acridines; Binding Sites; Chymotrypsin; Kinetics; Luminescent Measurements; Magnetic Resonance Spectroscopy; Microwaves; Proflavine; Protein Binding; Protein Conformation; Time Factors

1976
Photo-enhancement of the mutagenicity of 9-anilinoacridine derivatives related to the antitumour agent amsacrine.
    Mutation research, 1992, Volume: 268, Issue:1

    Topics: Acridines; Aminoacridines; Amsacrine; Antineoplastic Agents; Dose-Response Relationship, Drug; Frameshift Mutation; Light; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Proflavine; Salmonella typhimurium

1992
Mutation induction by 125iodoacetylproflavine, a DNA-intercalating agent, in human cells.
    International journal of radiation biology, 1990, Volume: 57, Issue:6

    Topics: Acridines; Cell Line; Cell Nucleus; Cell Survival; Humans; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Intercalating Agents; Iodine Radioisotopes; Mutation; Proflavine; Thymidine Kinase

1990
Limited effectiveness of triple dye in preventing colonization with methicillin-resistant Staphylococcus aureus in a special care nursery.
    The Pediatric infectious disease journal, 1990, Volume: 9, Issue:4

    Topics: Acridines; Anti-Infective Agents, Local; Coloring Agents; Cross Infection; Disease Outbreaks; Female; Gentian Violet; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Methicillin; Nurseries, Hospital; Penicillin Resistance; Proflavine; Quaternary Ammonium Compounds; Skin; Staphylococcal Infections; Staphylococcus aureus; Texas

1990
Synthesis and biological activity of the intercalating agent 3-acetamido-5-[123/125I]iodo-6-aminoacridine.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1990, Volume: 17, Issue:3

    Topics: Acridines; DNA; Humans; In Vitro Techniques; Intercalating Agents; Iodine Radioisotopes; Isotope Labeling; Male; Proflavine; Prostatic Neoplasms

1990
Intercalation complex of proflavine with DNA: structure and dynamics by solid-state NMR.
    Science (New York, N.Y.), 1990, Jul-06, Volume: 249, Issue:4964

    Topics: Acridines; DNA; Intercalating Agents; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleic Acid Conformation; Proflavine

1990
Effects of proflavin and photoactivated proflavin on the template function of single-stranded DNA.
    Journal of molecular biology, 1990, Jan-05, Volume: 211, Issue:1

    Topics: Acridines; Base Sequence; Chromosome Deletion; Coliphages; DNA Polymerase I; DNA Replication; DNA, Single-Stranded; Escherichia coli; Light; Molecular Sequence Data; Mutation; Proflavine; Templates, Genetic

1990
Three morphogenetic waves in early development of Physa acuta (Gastropoda, Pulmonata).
    Cell biology international reports, 1985, Volume: 9, Issue:10

    Topics: Acridines; Age Factors; Animals; Growth Inhibitors; Morphogenesis; Proflavine; RNA; Snails; Staining and Labeling; Time Factors; Transcription, Genetic

1985
Reversed-phase chromatography of novel biologically effective aminoacridine-N-glycosides by OPLC.
    Journal of chromatographic science, 1989, Volume: 27, Issue:5

    Topics: Acridines; Acriflavine; Aminoacridines; Chromatography, High Pressure Liquid; Glycosides; Hydrogen-Ion Concentration; Proflavine

1989
Occupational dermatitis from proflavine.
    Contact dermatitis, 1987, Volume: 17, Issue:4

    Topics: Acridines; Dermatitis, Occupational; Humans; Male; Middle Aged; Patch Tests; Proflavine; Pruritus

1987
'Petite' mutagenesis in Saccharomyces cerevisiae by a series of 2,7-di-alkyl-substituted derivatives of proflavine with differing DNA-binding properties.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: Acridines; Chemical Phenomena; Chemistry; Chemistry, Physical; DNA, Fungal; Intercalating Agents; Magnetic Resonance Spectroscopy; Mutagens; Mutation; Proflavine; Saccharomyces cerevisiae; Structure-Activity Relationship

1988
Mutagenesis by ethidium bromide, proflavine and mitomycin C in the cyanobacterium Nostoc sp.
    Mutation research, 1986, Volume: 174, Issue:3

    Topics: Acridines; Cyanobacteria; DNA; Ethidium; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Proflavine

1986
A molecular model for proflavine-DNA intercalation.
    Nucleic acids research, 1988, Sep-26, Volume: 16, Issue:18

    Topics: Acridines; Base Sequence; DNA; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Proflavine; Structure-Activity Relationship; X-Ray Diffraction

1988
Nonintercalative binding of proflavin to Z-DNA: structure of a complex between d(5BrC-G-5BrC-G) and proflavin.
    Biochemistry, 1988, Jul-26, Volume: 27, Issue:15

    Topics: Acridines; DNA; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Proflavine

1988
Perturbations to the intersystem crossing of proflavin upon binding to DNA and poly d(A-IU) from triplet-delayed emission spectroscopy.
    Biophysical journal, 1988, Volume: 54, Issue:4

    Topics: Acridines; DNA; Iodine; Luminescence; Mathematics; Models, Theoretical; Polydeoxyribonucleotides; Proflavine; Spectrometry, Fluorescence

1988
Mutagenicity and clastogenicity of proflavin in L5178Y/TK +/- -3.7.2.C cells.
    Mutation research, 1988, Volume: 204, Issue:2

    Topics: Acridines; Animals; Chromosome Aberrations; Leukemia L5178; Mice; Mutagenicity Tests; Neoplasm Proteins; Proflavine; Thymidine Kinase; Tumor Cells, Cultured

1988
Sequence-targeted photosensitized reactions in nucleic acids by oligo-alpha-deoxynucleotides and oligo-beta-deoxynucleotides covalently linked to proflavin.
    Biochemistry, 1988, Apr-19, Volume: 27, Issue:8

    Topics: Acridines; Base Sequence; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Photochemistry; Proflavine

1988
The induction of chromosomal aberrations and SCE by visible light in combination with dyes. I. The effect of hypoxia during light exposure in unsynchronized Chinese hamster ovary cells, sensitized with acridines.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: Acridine Orange; Acridines; Aminoacridines; Animals; Cell Line; Chromosome Aberrations; Coloring Agents; Cricetinae; Female; Light; Ovary; Oxygen; Proflavine; Sister Chromatid Exchange

1988
Reaction of nucleic acids and cis-diamminedichloroplatinum(II) in the presence of intercalating agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:17

    Topics: Acridines; Cisplatin; Ethidium; Guanine; Intercalating Agents; Nucleic Acid Conformation; Nucleic Acids; Polydeoxyribonucleotides; Proflavine

1986
Frameshift mutations produced by proflavin in bacteriophage T4: specificity within a hotspot.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:18

    Topics: Acridines; Aminacrine; Aminoacridines; Base Sequence; DNA, Viral; Mutagens; Mutation; Nitrogen Mustard Compounds; Proflavine; T-Phages

1986
Erythema multiforme-like and purpuric eruption due to contact allergy to proflavine.
    Contact dermatitis, 1987, Volume: 17, Issue:1

    Topics: Acridines; Adult; Dermatitis, Contact; Erythema Multiforme; Humans; Male; Patch Tests; Proflavine; Purpura

1987
Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-[alpha]-thymidylate covalently linked to an azidoproflavine derivative.
    Nucleic acids research, 1987, Oct-12, Volume: 15, Issue:19

    Topics: Acridines; Azides; Base Composition; Base Sequence; DNA; DNA Damage; DNA, Single-Stranded; Gene Expression Regulation; Photochemistry; Poly dA-dT; Poly T; Polydeoxyribonucleotides; Proflavine

1987
Proflavin binding to poly[d(A-T)] and poly[d(A-br5U)]: triplet state and temperature-jump kinetics.
    Biochemistry, 1986, Jul-15, Volume: 25, Issue:14

    Topics: Acridines; Kinetics; Nucleic Acid Conformation; Poly A-U; Poly dA-dT; Polydeoxyribonucleotides; Proflavine; Spectrometry, Fluorescence; Temperature; Thermodynamics

1986
Contact sensitivity to proflavine.
    International journal of dermatology, 1986, Volume: 25, Issue:7

    Topics: Acridines; Anti-Infective Agents, Local; Dermatitis, Contact; Female; Humans; Male; Patch Tests; Proflavine; Prospective Studies

1986
Investigation of DNA dynamics and drug-DNA interaction by steady state fluorescence anisotropy.
    Nucleic acids research, 1985, Apr-11, Volume: 13, Issue:7

    Topics: Acridines; Animals; Cattle; DNA; Ethidium; Fluorescence Polarization; Intercalating Agents; Mathematics; Molecular Weight; Nucleic Acid Conformation; Proflavine; Viscosity

1985
Nucleic acid binding drugs. Part XIII. Molecular motion in a drug-nucleic acid model system: thermal motion analysis of a proflavine-dinucleoside crystal structure.
    Nucleic acids research, 1985, Aug-12, Volume: 13, Issue:15

    Topics: Acridines; Chemical Phenomena; Chemistry, Physical; Crystallization; Cytidine Monophosphate; Cytosine Nucleotides; Dinucleoside Phosphates; Guanosine; Motion; Proflavine; Thermodynamics

1985
Photocarcinogenesis by methoxypsoralen, neutral red, proflavine, and long UV radiation.
    Cancer detection and prevention, 1985, Volume: 8, Issue:4

    Topics: Acridines; Animals; Female; Methoxsalen; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Neutral Red; Phenazines; Proflavine; Time Factors; Ultraviolet Rays

1985
[Influence of proflavine on the Feulgen reaction in hepatic cells of the white rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1974, Volume: 168, Issue:2-3

    Topics: Acridines; Animals; Chromatin; DNA; Freezing; Histocytochemistry; Injections, Intraperitoneal; Kinetics; Liver; Male; Microscopy, Fluorescence; Photometry; Proflavine; Rats

1974
Photodynamic tagging of poliovirus with proflavine.
    Research progress in organic, biological and medicinal chemistry, 1972, Volume: 3 Pt 1

    Topics: Acridines; Cells, Cultured; Light; Photochemistry; Poliovirus; Proflavine; Radiation Effects; Radiation-Sensitizing Agents; Virus Replication

1972
The elusive permeability barriers and binding sites for proflavine in Escherichia coli.
    Antimicrobial agents and chemotherapy, 1972, Volume: 1, Issue:6

    Topics: Acridines; Biological Assay; Cell Membrane Permeability; Escherichia coli; Osmosis; Proflavine

1972
DNA synthesis on phi X174 template damaged by proflavine and light treatment.
    Photochemistry and photobiology, 1982, Volume: 35, Issue:5

    Topics: Acridines; Bacteriophage phi X 174; DNA Replication; Light; Proflavine; Ultraviolet Rays; Virus Replication

1982
Terminations of DNA synthesis on 'proflavine and light'-treated phi X174 single-stranded DNA.
    Biochimica et biophysica acta, 1984, Apr-05, Volume: 781, Issue:3

    Topics: Acridines; Bacteriophage phi X 174; Base Sequence; DNA Polymerase I; DNA Replication; DNA, Single-Stranded; Escherichia coli; Light; Photolysis; Proflavine

1984
Frameshift mutagenesis of lambda prophage by 9-aminoacridine, proflavin and ICR-191.
    Molecular & general genetics : MGG, 1984, Volume: 195, Issue:3

    Topics: Acridines; Aminacrine; Aminoacridines; Bacteriophage lambda; Base Sequence; DNA, Viral; Mutagens; Mutation; Nitrogen Mustard Compounds; Proflavine

1984
Visible-light-induced OH radicals in DNA-proflavine complexes: an e.p.r. and spin trapping study.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1982, Volume: 42, Issue:2

    Topics: Acridines; Cyclic N-Oxides; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Light; Proflavine; Spin Labels

1982
Visualization of drug-nucleic acid interactions at atomic resolution. IX. Structures of two N,N-dimethylproflavine: 5-iodocytidylyl (3'-5') guanosine crystalline complexes.
    Journal of biomolecular structure & dynamics, 1984, Volume: 1, Issue:5

    Topics: Acridines; Binding Sites; Crystallization; Dinucleoside Phosphates; Intercalating Agents; Molecular Conformation; Molecular Structure; Proflavine

1984
Visualization of drug-nucleic acid interactions at atomic resolution. X. Structure of a N,N-dimethylproflavine: deoxycytidylyl(3'-5')deoxyguanosine crystalline complex.
    Journal of biomolecular structure & dynamics, 1984, Volume: 1, Issue:5

    Topics: Acridines; Binding Sites; Crystallization; Deoxycytosine Nucleotides; Deoxyguanosine; Intercalating Agents; Molecular Conformation; Molecular Structure; Proflavine

1984
Networks of water molecules in a proflavine deoxydinucleoside phosphate complex.
    Journal of biomolecular structure & dynamics, 1983, Volume: 1, Issue:1

    Topics: Acridines; Computer Simulation; Deoxycytosine Nucleotides; Deoxyguanosine; Molecular Conformation; Molecular Structure; Monte Carlo Method; Proflavine; Thermodynamics; Water; X-Ray Diffraction

1983
Monte Carlo studies on water in the dCpG/proflavin crystal hydrate.
    Journal of biomolecular structure & dynamics, 1983, Volume: 1, Issue:1

    Topics: Acridines; Binding Sites; Deoxycytosine Nucleotides; Deoxyguanosine; Molecular Structure; Monte Carlo Method; Proflavine; Thermodynamics; Water; X-Ray Diffraction

1983
Proflavine binding to poly(rC-rA) inverts the CD spectrum but not the helix handedness.
    Journal of biomolecular structure & dynamics, 1984, Volume: 2, Issue:1

    Topics: Acridines; Base Composition; Binding Sites; Circular Dichroism; Intercalating Agents; Molecular Structure; Nucleic Acid Conformation; Poly A; Poly C; Polyribonucleotides; Proflavine

1984
Transient removal of proflavine inhibition of bovine beta-trypsin by the bovine basic pancreatic trypsin inhibitor (Kunitz). A case for "chronosteric effects".
    The Journal of biological chemistry, 1983, Apr-25, Volume: 258, Issue:8

    Topics: Acridines; Animals; Cattle; Hydrolysis; Lysine; Proflavine; Time Factors; Trypsin; Trypsin Inhibitor, Kunitz Soybean; Trypsin Inhibitors

1983
Mechanism for strand-break induction in DNA-proflavine complexes exposed to visible light.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1981, Volume: 40, Issue:4

    Topics: Acridines; Bacteriophage phi X 174; Chemical Phenomena; Chemistry; DNA; Electrophoresis, Agar Gel; Free Radicals; Light; Oxygen; Proflavine

1981
Flow cytometric analysis of proflavine uptake into normal rat hepatocytes and cells arising during AAF-induced hepatocarcinogenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:9

    Topics: 2-Acetylaminofluorene; Acridines; Animals; Azides; Cell Nucleus; Flow Cytometry; In Vitro Techniques; Liver; Liver Neoplasms; Male; Proflavine; Rats; Rats, Inbred Strains; Sodium Azide

1984
Release of proflavine hemisulphate from proflavine preparations currently in use within the Mersey Regional Health Authority.
    Journal of clinical and hospital pharmacy, 1983, Volume: 8, Issue:4

    Topics: Acridines; Chemistry, Pharmaceutical; Diffusion; England; Ointments; Proflavine; Solutions

1983
Studies on transcription termination and splicing of the rRNA precursor in vivo in the presence of proflavine.
    Nucleic acids research, 1984, Jan-25, Volume: 12, Issue:2

    Topics: Acridines; Animals; Cell Nucleolus; DNA; DNA, Ribosomal; Genes; Microscopy, Electron; Nucleic Acid Conformation; Nucleic Acid Hybridization; Proflavine; RNA, Ribosomal; Tetrahymena; Transcription, Genetic

1984
Proflavin binding within the fibrinopeptide groove adjacent to the catalytic site of human alpha-thrombin.
    Biochemistry, 1984, Apr-10, Volume: 23, Issue:8

    Topics: Acridines; Animals; Binding Sites; Cattle; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Kinetics; Proflavine; Protein Binding; Protein Conformation; Structure-Activity Relationship; Thrombin

1984
Umbilical cord care. A study of bacitracin ointment vs. triple dye.
    Clinical pediatrics, 1984, Volume: 23, Issue:6

    Topics: Acridines; Anti-Bacterial Agents; Bacitracin; Bacterial Infections; Drug Combinations; Drug Therapy, Combination; Gentian Violet; Humans; Infant Care; Infant, Newborn; Nurseries, Hospital; Ointments; Proflavine; Quaternary Ammonium Compounds; Retrospective Studies; Staphylococcus; Streptococcus; Umbilical Cord

1984
X-ray crystallographic analysis of a ternary intercalation complex between proflavine and the dinucleoside monophosphates CpA and UpG.
    Biopolymers, 1984, Volume: 23, Issue:6

    Topics: Acridines; Adenosine; Cytidine Monophosphate; Cytosine Nucleotides; Dinucleoside Phosphates; Guanosine; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Proflavine; Uracil Nucleotides; Uridine Monophosphate; X-Ray Diffraction

1984
DNA binding and growth inhibitory properties of a series of 2,7-di-alkyl-substituted derivatives of proflavine.
    Chemico-biological interactions, 1982, Volume: 42, Issue:1

    Topics: Acridines; DNA, Circular; In Vitro Techniques; Intercalating Agents; Mutagenicity Tests; Proflavine; Salmonella typhimurium

1982
Fluorescence relaxation of proflavin-deoxyribonucleic acid interaction. Kinetic properties of a base-specific reaction.
    Biochemistry, 1980, Aug-19, Volume: 19, Issue:17

    Topics: Acridines; Bacillus megaterium; DNA, Bacterial; Kinetics; Mathematics; Micrococcus; Polydeoxyribonucleotides; Proflavine; Spectrometry, Fluorescence; Structure-Activity Relationship

1980
Mutation to acriflavine resistance in some myxobacteria.
    Microbios, 1980, Volume: 27, Issue:109 110

    Topics: Acridines; Acriflavine; Drug Resistance, Microbial; Ethidium; Genes; Mutation; Myxococcales; Proflavine

1980
X-ray-structure of a cytidylyl-3',5'-adenosine-proflavine complex: a self-paired parallel-chain double helical dimer with an intercalated acridine dye.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:4

    Topics: Acridines; Hydrogen Bonding; Intercalating Agents; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Proflavine; Solvents; X-Ray Diffraction

1980
Quantum chemical calculations on the two-step mechanism of proflavin binding to DNA.
    Annals of the New York Academy of Sciences, 1981, Volume: 367

    Topics: Acridines; Base Sequence; DNA; Hydrogen Bonding; Proflavine; Quantum Theory; Thermodynamics

1981
Theoretical studies of the structure and energies of base-paired nucleotides and the dissociation kinetics of a proflavine-dinucleotide complex.
    Annals of the New York Academy of Sciences, 1981, Volume: 367

    Topics: Acridines; Base Sequence; DNA; Kinetics; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Proflavine; Thermodynamics

1981
Proflavin: an unusual mutagen.
    Mutation research, 1980, Volume: 77, Issue:1

    Topics: Acridines; Animals; Cricetinae; Genetic Code; Genetic Techniques; Light; Mice; Mutagens; Mutation; Proflavine; Rats; Salmonella typhimurium; Transcription, Genetic

1980
Photo-oxidation of L-glutamate decarboxylase from Escherichia coli, sensitized by the coenzyme pyridoxal phosphate and by proflavin.
    Biochimica et biophysica acta, 1980, May-29, Volume: 623, Issue:1

    Topics: Acridines; Carboxy-Lyases; Chromatography, Ion Exchange; Circular Dichroism; Escherichia coli; Glutamate Decarboxylase; Kinetics; Light; Oxidation-Reduction; Photochemistry; Proflavine; Pyridoxal Phosphate

1980
Dependence of the mutagenic power of heteroatomic dyes on their DNA-base-pair specificity.
    Mutation research, 1981, Volume: 91, Issue:3

    Topics: Acridines; Base Sequence; Coloring Agents; DNA; Hydrogen Bonding; Intercalating Agents; Mutagenicity Tests; Mutagens; Proflavine; Salmonella typhimurium; Structure-Activity Relationship

1981
Interaction of proflavine with 2-hydroxy-5-nitrobenzylated papain.
    Biochemical and biophysical research communications, 1982, Apr-14, Volume: 105, Issue:3

    Topics: Acridines; Enzyme Activation; Glycine; Indicators and Reagents; Kinetics; Papain; Proflavine; Protein Binding; Spectrometry, Fluorescence; Substrate Specificity

1982
Comparative mutagenicity of 4 DNA-intercalating agents in L5178Y mouse lymphoma cells.
    Mutation research, 1982, Volume: 102, Issue:4

    Topics: Acridine Orange; Acridines; Animals; Cell Survival; Ethidium; Intercalating Agents; Leukemia L5178; Leukemia, Experimental; Methyl Methanesulfonate; Mice; Mutagens; Mutation; Proflavine; Quinacrine; Quinacrine Mustard

1982
Molecular mechanical studies of proflavine and acridine orange intercalation.
    Nucleic acids research, 1981, Mar-25, Volume: 9, Issue:6

    Topics: Acridine Orange; Acridines; Chemical Phenomena; Chemistry; Computers; Mathematics; Molecular Conformation; Nucleic Acid Conformation; Oligoribonucleotides; Proflavine; Structure-Activity Relationship

1981
The effects of photooxidation by proflavine on HeLa cells-I. The molecular mechanisms.
    Photochemistry and photobiology, 1981, Volume: 33, Issue:1

    Topics: Acridines; DNA; Free Radicals; HeLa Cells; Humans; Kinetics; Oxidation-Reduction; Photochemistry; Proflavine

1981
The effects of photooxidation by proflavine on HeLa cells-II. Damage to DNA.
    Photochemistry and photobiology, 1981, Volume: 33, Issue:1

    Topics: Acridines; Cell Nucleus; DNA; HeLa Cells; Humans; Oxidation-Reduction; Photochemistry; Proflavine

1981
Alteration of guanine residues during proflavine mediated photosensitization of DNA.
    Photochemistry and photobiology, 1981, Volume: 33, Issue:3

    Topics: Acridines; Chemical Phenomena; Chemistry; DNA; Guanine; Light; Proflavine

1981
The structure of drug-deoxydinucleoside phosphate complex; generalized conformational behavior of intercalation complexes with RNA and DNA fragments.
    Nucleic acids research, 1980, Jan-11, Volume: 8, Issue:1

    Topics: Acridines; DNA; Molecular Conformation; Nucleic Acid Conformation; Oligonucleotides; Proflavine; RNA; Structure-Activity Relationship; X-Ray Diffraction

1980
Highly structured water network in crystals of a deoxydinucleoside---drug complex.
    Nature, 1980, Nov-13, Volume: 288, Issue:5787

    Topics: Acridines; Crystallography; Hydrogen Bonding; Molecular Conformation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Proflavine; Water; X-Ray Diffraction

1980
Crystallographic studies of drug-nucleic acid interactions: proflavine intercalation between the non-complementary base-pairs of cytidilyl-3',5'-adenosine.
    Journal of molecular biology, 1980, Sep-25, Volume: 142, Issue:3

    Topics: Acridines; Adenosine; Base Composition; Binding Sites; Cytidine Monophosphate; Cytosine; Cytosine Nucleotides; Dinucleoside Phosphates; Hydrogen Bonding; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Proflavine; Water

1980
Effect of proflavine and its 2,7-dialkyl substituted derivatives upon initiation of transcription.
    Acta biochimica Polonica, 1993, Volume: 40, Issue:1

    Topics: Acridines; DNA; Proflavine; Promoter Regions, Genetic; Receptors, Interleukin-2; Ribonucleases; RNA; Transcription, Genetic

1993
The absorption of proflavine by gram-positive and gram-negative organisms.
    Experimental cell research, 1954, Volume: 7, Issue:2

    Topics: Acridines; Bacteria; Coloring Agents; Humans; Proflavine

1954
Proflavine sulphate poisoning.
    Journal of the Indian Medical Association, 1955, Jul-16, Volume: 25, Issue:4

    Topics: Acridines; Coloring Agents; Humans; Poisoning; Proflavine; Sulfates

1955
The effect of proflavine on the adaptive enzyme synthesis.
    Acta physiologica Academiae Scientiarum Hungaricae, 1957, Volume: 12, Issue:1-3

    Topics: Acridines; Bacteria; Enzymes; Proflavine

1957
Studies on the induction of mutations in poliovirus by proflavin.
    Virology, 1958, Volume: 5, Issue:2

    Topics: Acridines; Mutation; Poliomyelitis; Poliovirus; Proflavine

1958
Distribution of proflavin-induced mutations in the genetic fine structure.
    Nature, 1958, Oct-11, Volume: 182, Issue:4641

    Topics: Acridines; Bacteriophages; Escherichia coli; Mutation; Proflavine; Uracil

1958
The synthesis of fowl plague virus products in a proflavine-inhibited tissue culture system.
    Virology, 1958, Volume: 6, Issue:2

    Topics: Acridines; Animals; Influenza A virus; Proflavine; Viruses

1958
The origin of bacterial resistance to proflavine. I. Training and reversion in Escherichia coll.
    Journal of general microbiology, 1959, Volume: 20, Issue:2

    Topics: Acridines; Escherichia; Escherichia coli; Proflavine

1959
2. Spontaneous mutation to proflavine resistance in Escherichia coli.
    Journal of general microbiology, 1959, Volume: 20, Issue:2

    Topics: Acridines; Escherichia coli; Mutation; Proflavine

1959
3. The alleged rapid adaptation to proflavine resistance in Bacterium lactis aerogenes. (syn. Aerobacter aerogenes, Klebsiella pneumoniae).
    Journal of general microbiology, 1959, Volume: 20, Issue:2

    Topics: Acclimatization; Acridines; Adaptation, Physiological; Bacteria; Enterobacter aerogenes; Klebsiella pneumoniae; Proflavine

1959
5. Transformation of proflavine resistance in Escherichia coli.
    Journal of general microbiology, 1959, Volume: 20, Issue:2

    Topics: Acridines; Biochemical Phenomena; Escherichia coli; Proflavine

1959
Effect of proflavine on the formation of the virus of foot-and-mouth disease and its infective ribonucleic acid in pig kidney tissue culture monolayers.
    Nature, 1959, Sep-05, Volume: 184

    Topics: Acridines; Animals; Cell Culture Techniques; Foot-and-Mouth Disease; Kidney; Proflavine; RNA; Sus scrofa; Swine

1959
Photo-oxidation, sensitized by proflavine, of a number of protein constituents.
    Biochimica et biophysica acta, 1962, Jul-16, Volume: 60

    Topics: Acridines; Amino Acids; Light; Oxidation-Reduction; Proflavine

1962
Effect of proflavine on the synthesis of adenovirus, type 5, and associated soluble antigens.
    Journal of bacteriology, 1962, Volume: 84

    Topics: Acridines; Adenoviridae; Antigens; HeLa Cells; Humans; Proflavine

1962
The effect of proflavine on the hemagglutinating activity of Reo and ECHO viruses.
    Canadian journal of microbiology, 1962, Volume: 8

    Topics: Acridines; Enterovirus B, Human; Hemagglutination; Hemagglutination Tests; Humans; Proflavine; Viruses

1962
RESISTANCE AND CROSS-RESISTANCE OF ESCHERICHIA COLI S MUTANTS TO THE RADIOMIMETIC AGENT PROFLAVINE.
    Journal of bacteriology, 1964, Volume: 87

    Topics: Acridines; Antimetabolites; Drug Resistance, Microbial; Escherichia coli; Mutation; Proflavine; Radiation Effects; Research; Ultraviolet Rays

1964
[THERMODYNAMIC STUDY OF THE ADSORPTION OF PROFLAVIN ON DESOXYRIBONUCLEIC ACID].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, May-11, Volume: 258

    Topics: Acridines; Adsorption; Biochemical Phenomena; Biochemistry; DNA; Proflavine; Research; Thermodynamics; Thymus Gland

1964
EFFECTS OF DINITROPHENOL AND PROFLAVINE ON INFORMATION TRANSFER MECHANISMS IN ESCHERICHIA COLI; A STUDY IN VIVO AND IN VITRO.
    Biochimica et biophysica acta, 1964, Jul-22, Volume: 87

    Topics: Acridines; Dinitrophenols; DNA; DNA, Viral; Escherichia coli; In Vitro Techniques; Nucleotides; Pharmacology; Phenylalanine; Proflavine; Proteins; Research; RNA; RNA, Bacterial; Spectrophotometry; Threonine

1964
BINDING OF PROFLAVINE TO DEOXYRIBONUCLEIC ACID AND RIBONUCLEIC ACID AND ITS BIOLOGICAL SIGNIFICANCE.
    Nature, 1964, Oct-03, Volume: 204

    Topics: Acridines; Animals; DNA; Fibroblasts; Influenza A virus; Leucine; Metabolism; Newcastle disease virus; Nucleosides; Pharmacology; Poultry; Proflavine; Proteins; Research; RNA; Tissue Culture Techniques; Virus Cultivation

1964
INTERFERENCE BETWEEN PROFLAVINE TREATED REOVIRUS AND RELATED AND UNRELATED VIRUSES.
    Archiv fur die gesamte Virusforschung, 1965, Volume: 15

    Topics: Acridines; Adenoviridae; Antibody Formation; Enterovirus; Enterovirus B, Human; Enterovirus C, Human; Pharmacology; Poliovirus; Proflavine; Reoviridae; Research; Vaccinia virus; Viral Interference; Viral Proteins; Virus Cultivation; Viruses

1965
PROFLAVINE INHIBITION OF VACCINIA VIRUS SYNTHESIS.
    Journal of bacteriology, 1965, Volume: 89

    Topics: Acridines; Antigens; DNA; DNA, Viral; Hemagglutination Inhibition Tests; Humans; Metabolism; Proflavine; Research; RNA; RNA, Viral; Vaccinia virus

1965
[THE BONDING OF PROFLAVIN AND ACTINOMYCIN TO DESOXYRIBONUCLEIC ACID. I. THE INFLUENCE OF ION STRENGTH AND PH AS WELL AS THE EFFECTS OF UREA ON THE BONDING].
    Biochemische Zeitschrift, 1964, Sep-28, Volume: 340

    Topics: Acridines; Dactinomycin; DNA; Object Attachment; Osmolar Concentration; Proflavine; Research; Urea

1964
SYNTHESIS OF AN ABNORMAL RIBONUCLEIC ACID IN THE PRESENCE OF PROFLAVINE.
    Biochimica et biophysica acta, 1965, May-11, Volume: 103

    Topics: Acridines; Adenine Nucleotides; Animals; Biochemical Phenomena; Biochemistry; Chick Embryo; Cytosine Nucleotides; Fibroblasts; Guanine Nucleotides; Metabolism; Nucleosides; Pharmacology; Phosphorus; Phosphorus Isotopes; Proflavine; Research; Research Design; RNA; Tissue Culture Techniques; Uracil Nucleotides; Uridine

1965
Photodynamic action of proflavine on T2 coliphage.
    Virology, 1959, Volume: 9

    Topics: Acridines; Bacteriophage T4; Humans; Proflavine

1959
The inhibition of bacteriophage multiplication by proflavine and its reversal by certain polyamines.
    The Biochemical journal, 1959, Volume: 73

    Topics: Acridines; Amines; Bacteriophages; Humans; Polyamines; Proflavine

1959
The rate of proflavin passage into single living cells with application to permeability studies.
    The Journal of general physiology, 1960, Volume: 43

    Topics: Acridines; Biological Transport; Kinetics; Permeability; Proflavine; Tissue Culture Techniques

1960
[The effect of 3,6-diaminoacridine on the growth and cell division of Ehrlich ascites tumor].
    Zeitschrift fur Krebsforschung, 1959, Volume: 63

    Topics: Acridines; Animals; Biological Phenomena; Carcinoma, Ehrlich Tumor; Cell Division; Neoplasms, Experimental; Physiological Phenomena; Proflavine

1959
Interaction of DNA and proflavine: a small-angle x-ray scattering study.
    Journal of molecular biology, 1961, Volume: 3

    Topics: Acridines; DNA; Flavins; Proflavine; X-Rays

1961
Effect of local irrigation with proflavine hemisulfate on wounds seeded with tumor cells. An experimental study.
    Annals of surgery, 1962, Volume: 155

    Topics: Acridines; Animals; Humans; Neoplasms, Experimental; Proflavine

1962
The effect of proflavine on the growth of viruses in the chick embryo.
    Journal of immunology (Baltimore, Md. : 1950), 1951, Volume: 67, Issue:5

    Topics: Acridines; Animals; Chick Embryo; Coloring Agents; Proflavine; Viruses

1951
The resistance of Bact. lactis aerogenes to proflavine (2:8-diaminoacridine). I. The applicability of the statistical fluctuation test.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1952, Feb-28, Volume: 139, Issue:895

    Topics: Acridines; Biochemical Phenomena; Coloring Agents; Enterobacter aerogenes; Proflavine

1952
The resistance of Bact. lactis aerogenes to proflavine (2:8-diaminoacridine). II. The direct induction of adaptation.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1952, Feb-28, Volume: 139, Issue:895

    Topics: Acclimatization; Acridines; Adaptation, Physiological; Biochemical Phenomena; Coloring Agents; Enterobacter aerogenes; Proflavine

1952
Fluorescence of acridinic dyes in anionic surfactant solution.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:13-14

    Topics: Acridines; Aminacrine; Amination; Anions; Coloring Agents; Fluorescence; Molecular Structure; Proflavine; Sodium Dodecyl Sulfate; Solutions; Surface-Active Agents

2005
Inhibiting protein-amyloid interactions with small molecules: a surface chemistry approach.
    Bioorganic & medicinal chemistry letters, 2006, Feb-15, Volume: 16, Issue:4

    Topics: Acridines; Amyloid; Benzothiazoles; Enzyme-Linked Immunosorbent Assay; Immunoglobulin G; Molecular Structure; Proflavine; Protein Binding; Proteins; Surface Properties; Thiazoles

2006
Synthesis and antileishmanial activity of 6-mono-substituted and 3,6-di-substituted acridines obtained by acylation of proflavine.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:10

    Topics: Acridines; Acylation; Animals; Antiprotozoal Agents; Leishmania infantum; Molecular Structure; Proflavine

2007
Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1',1''-(acridin-3,6-diyl)-3',3''-dialkyldiureas.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Acridines; Alkylation; Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Line, Tumor; DNA; Humans; Molecular Structure; Photochemistry; Proflavine; Spectrophotometry; Structure-Activity Relationship; Titrimetry; Urea

2008
Photo-inducible cytotoxic and clastogenic activities of 3,6-di-substituted acridines obtained by acylation of proflavine.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Acridines; Acylation; Animals; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Humans; Keratinocytes; Light; Micronucleus Tests; Molecular Structure; Photochemistry; Proflavine; Stereoisomerism; Structure-Activity Relationship

2009
Magnetic field effect corroborated with docking study to explore photoinduced electron transfer in drug-protein interaction.
    The journal of physical chemistry. A, 2010, Dec-30, Volume: 114, Issue:51

    Topics: Acridines; Algorithms; Aminoacridines; Antineoplastic Agents; Binding Sites; Circular Dichroism; Electromagnetic Fields; Electron Transport; Free Radicals; Humans; Ions; Photochemistry; Proflavine; Protein Binding; Serum Albumin; Spectrometry, Fluorescence

2010
Subcellular localization of proflavine derivative and induction of oxidative stress--in vitro studies.
    Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21

    Topics: Acridines; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Fluorescent Dyes; HL-60 Cells; Humans; Mice; Microscopy, Confocal; Mitochondria; NIH 3T3 Cells; Oxidative Stress; Proflavine; Reactive Oxygen Species

2013
Excited-State Dynamics of Proflavine after Intercalation into DNA Duplex.
    Molecules (Basel, Switzerland), 2022, Nov-23, Volume: 27, Issue:23

    Topics: Acridines; DNA; Intercalating Agents; Proflavine

2022