Page last updated: 2024-09-03

profenamine hydrochloride and edrophonium chloride

profenamine hydrochloride has been researched along with edrophonium chloride in 2 studies

Compound Research Comparison

Studies (profenamine hydrochloride)	Trials (profenamine hydrochloride)	Recent Studies (post-2010) (profenamine hydrochloride)	Studies (edrophonium chloride)	Trials (edrophonium chloride)	Recent Studies (post-2010) (edrophonium chloride)
18	0	15	28	0	17

Protein Interaction Comparison

Protein	Taxonomy	edrophonium chloride (IC50)
Sterol O-acyltransferase 1	Rattus norvegicus (Norway rat)	0.5
Acetylcholinesterase	Homo sapiens (human)	3.208
Acetylcholinesterase	Bos taurus (cattle)	0.05
Sterol O-acyltransferase 1	Homo sapiens (human)	0.5

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dohnal, V; Dolezal, M; Holas, O; Hrabinova, M; Komloova, M; Kuca, K; Musilek, K; Nachon, F; Pohanka, M	1
Dohnal, V; Gunn-Moore, F; Holas, O; Horova, A; Komloova, M; Kuca, K; Musilek, K	1

Other Studies

2 other study(ies) available for profenamine hydrochloride and edrophonium chloride

Article	Year
Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Humans; Isoquinolines; Models, Molecular; Molecular Structure; Myasthenia Gravis; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship	2011
Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment. Bioorganic & medicinal chemistry letters, 2011, Apr-15, Volume: 21, Issue:8 Topics: Acetylcholinesterase; Ambenonium Chloride; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Edrophonium; Humans; Kinetics; Molecular Dynamics Simulation; Myasthenia Gravis; Protein Binding; Quinolinium Compounds; Recombinant Proteins; Structure-Activity Relationship	2011

Article

Year

Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment.

European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Humans; Isoquinolines; Models, Molecular; Molecular Structure; Myasthenia Gravis; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship

2011

Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.

Bioorganic & medicinal chemistry letters, 2011, Apr-15, Volume: 21, Issue:8

Topics: Acetylcholinesterase; Ambenonium Chloride; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Edrophonium; Humans; Kinetics; Molecular Dynamics Simulation; Myasthenia Gravis; Protein Binding; Quinolinium Compounds; Recombinant Proteins; Structure-Activity Relationship

2011