Compounds > procyclidine
Page last updated: 2024-08-16

procyclidine and physostigmine

procyclidine has been researched along with physostigmine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hardern, R; Page, AV; Teoh, R1
Aas, P; Enger, S; Myhrer, T2
Aas, P; Andersen, JM; Myhrer, T; Nguyen, NH1
Che, JH; Choi, EK; Ha, YC; Hur, GH; Hwang, SY; Jang, JY; Kim, DJ; Kim, J; Kim, JC; Kim, YB; Park, D; Seong, YH; Shin, S; Yon, JM1
Cho, Y; Choi, EK; Huang, ZZ; Hwang, SY; Kang, JK; Kim, JC; Kim, WS; Kim, YB; Nam, SY; Park, SH; Shin, S1
Cho, Y; Ha, YC; Hur, GH; Kim, WS1
Aas, P; Enger, S; Mariussen, E; Myhrer, T1

Reviews

1 review(s) available for procyclidine and physostigmine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for procyclidine and physostigmine

ArticleYear
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Physostigmine as treatment for severe CNS anticholinergic toxicity.
    Emergency medicine journal : EMJ, 2001, Volume: 18, Issue:5

    Topics: Amisulpride; Antipsychotic Agents; Cholinesterase Inhibitors; Drug Overdose; Humans; Male; Muscarinic Antagonists; Physostigmine; Poisoning; Procyclidine; Sulpiride

2001
Cognitive side effects in rats caused by pharmacological agents used to prevent soman-induced lethality.
    European journal of pharmacology, 2004, Jan-12, Volume: 483, Issue:2-3

    Topics: Animals; Cognition Disorders; Drug Therapy, Combination; Exploratory Behavior; Lethal Dose 50; Male; Physostigmine; Procyclidine; Rats; Rats, Wistar; Scopolamine; Soman

2004
Protection against soman-induced seizures in rats: relationship among doses of prophylactics, soman, and adjuncts.
    Toxicology and applied pharmacology, 2004, May-01, Volume: 196, Issue:3

    Topics: Animals; Cholinesterase Inhibitors; Convulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Male; Muscarinic Antagonists; Neuroprotective Agents; Physostigmine; Procyclidine; Rats; Rats, Wistar; Scopolamine; Seizures; Soman

2004
Protection by sustained release of physostigmine and procyclidine of soman poisoning in rats.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: Animals; Avoidance Learning; Blood-Brain Barrier; Brain; Capillary Permeability; Cholinesterase Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Infusion Pumps; Male; Memory; Muscarinic Antagonists; Physostigmine; Procyclidine; Rats; Rats, Sprague-Dawley; Seizures; Soman; Specific Pathogen-Free Organisms; Time Factors

2004
Protection by a transdermal patch containing physostigmine and procyclidine of soman poisoning in dogs.
    European journal of pharmacology, 2005, Nov-21, Volume: 525, Issue:1-3

    Topics: Administration, Cutaneous; Animals; Atropine; Cholinesterase Inhibitors; Dogs; Female; Muscarinic Antagonists; Neuroprotective Agents; Oximes; Physostigmine; Procyclidine; Pyridinium Compounds; Soman

2005
Antiparkinson drugs used as prophylactics for nerve agents: studies of cognitive side effects in rats.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:4

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Benactyzine; Biperiden; Cholinergic Antagonists; Cholinesterase Inhibitors; Cognition; Cyclopentanes; Exploratory Behavior; Male; Motor Activity; Neurotoxins; Organophosphorus Compounds; Physostigmine; Procyclidine; Rats; Rats, Wistar; Trihexyphenidyl

2008
Minimum effective drug concentrations of a transdermal patch system containing procyclidine and physostigmine for prophylaxis against soman poisoning in rhesus monkeys.
    Environmental toxicology and pharmacology, 2012, Volume: 33, Issue:1

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Macaca mulatta; Male; Muscarinic Antagonists; Oximes; Physostigmine; Poisoning; Procyclidine; Pyridinium Compounds; Soman; Transdermal Patch

2012
Two medical therapies very effective shortly after high levels of soman poisoning in rats, but only one with universal utility.
    Toxicology, 2013, Dec-15, Volume: 314, Issue:2-3

    Topics: Animals; Anticonvulsants; Male; Neuroprotective Agents; Physostigmine; Procyclidine; Rats; Rats, Wistar; Seizures; Soman; Time Factors; Treatment Outcome

2013