Page last updated: 2024-09-03

procyanidin b2 and quercetin

procyanidin b2 has been researched along with quercetin in 23 studies

Compound Research Comparison

Studies
(procyanidin b2)
Trials
(procyanidin b2)
Recent Studies (post-2010)
(procyanidin b2)
Studies
(quercetin)
Trials
(quercetin)
Recent Studies (post-2010) (quercetin)
208315512,4032397,510

Protein Interaction Comparison

ProteinTaxonomyprocyanidin b2 (IC50)quercetin (IC50)
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))2.2
hexokinaseTrypanosoma brucei brucei TREU92722.378
Maltase-glucoamylase, intestinalHomo sapiens (human)7.8
NUAK family SNF1-like kinase 1Homo sapiens (human)5.09
Lysine-specific histone demethylase 1AHomo sapiens (human)1.26
B2 bradykinin receptorCavia porcellus (domestic guinea pig)4
Arginase Leishmania amazonensis4
Epidermal growth factor receptorHomo sapiens (human)0.9
ProthrombinHomo sapiens (human)1.5
Cationic trypsinBos taurus (cattle)7.1
Beta-lactamaseEscherichia coli K-124
NeuraminidaseInfluenza A virus (A/Puerto Rico/8/1934(H1N1))7.75
Interstitial collagenaseHomo sapiens (human)1.49
Phospholipase A2Homo sapiens (human)2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)9
Cytochrome P450 1A1Homo sapiens (human)5.5455
Amyloid-beta precursor proteinHomo sapiens (human)7.94
MyeloperoxidaseHomo sapiens (human)1.6975
Cytochrome P450 1A2Homo sapiens (human)4.097
Cyclin-dependent kinase 1Homo sapiens (human)0.45
Glycogen phosphorylase, liver formHomo sapiens (human)4.8
Epoxide hydrolase 1 Homo sapiens (human)7
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)6.6417
Insulin-like growth factor 1 receptorHomo sapiens (human)0.3
Neutrophil elastaseHomo sapiens (human)22.378
72 kDa type IV collagenaseHomo sapiens (human)6.68
Stromelysin-1Homo sapiens (human)5.57
Hepatocyte growth factor receptorHomo sapiens (human)0.58
Cytochrome P450 3A4Homo sapiens (human)7
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)2.6975
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus8.1
Lysosomal alpha-glucosidaseHomo sapiens (human)7.8
SialidaseClostridium perfringens4.7333
Malate dehydrogenaseThermus thermophilus6
Cytochrome P450 2C8Homo sapiens (human)7
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.7686
AromataseHomo sapiens (human)0.012
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)1.95
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)0.43
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.12
Sucrase-isomaltase, intestinalHomo sapiens (human)7.8
Matrix metalloproteinase-9Homo sapiens (human)0.8919
Serine/threonine-protein kinase B-rafHomo sapiens (human)7.589
Aldo-keto reductase family 1 member B1Homo sapiens (human)2.2141
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)2.1
Polyunsaturated fatty acid lipoxygenase ALOX15Homo sapiens (human)2.2
Aldo-keto reductase family 1 member B1Bos taurus (cattle)2.85
Polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)0.44
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)2.1
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4
Casein kinase II subunit alpha'Homo sapiens (human)1.65
Amine oxidase [flavin-containing] AHomo sapiens (human)2.62
Amine oxidase [flavin-containing] A Bos taurus (cattle)0.01
C-X-C chemokine receptor type 1Homo sapiens (human)4.7559
Dipeptidyl peptidase 4Homo sapiens (human)2.92
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)3.8
Proteasome subunit beta type-5Homo sapiens (human)2.75
Vasopressin V2 receptorHomo sapiens (human)6.6548
Tyrosine-protein kinase receptor UFOHomo sapiens (human)0.96
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)1
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)5.39
Bifunctional epoxide hydrolase 2Homo sapiens (human)7
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.97
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.59
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)1.54
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)1
Collagenase 3Homo sapiens (human)8.46
1-deoxy-D-xylulose 5-phosphate reductoisomeraseEscherichia coli K-121.9
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.04
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)3.8
Glycogen synthase kinase-3 alphaHomo sapiens (human)2.1
Glycogen synthase kinase-3 betaHomo sapiens (human)2.1
Aldo-keto reductase family 1 member A1Rattus norvegicus (Norway rat)2.32
C-C chemokine receptor type 4Homo sapiens (human)10
Serine/threonine-protein kinase Nek2Homo sapiens (human)5.73
Serine/threonine-protein kinase PLK1Homo sapiens (human)5.75
Death-associated protein kinase 1Homo sapiens (human)8.9
Mitogen-activated protein kinase 10Homo sapiens (human)2.88
Beta-secretase 1Homo sapiens (human)6.05
Casein kinase II subunit betaHomo sapiens (human)1.65
Casein kinase II subunit alphaHomo sapiens (human)1.65
LactoperoxidaseBos taurus (cattle)6.1
Cyclin-dependent kinase 6Homo sapiens (human)2.1
Cyclin-dependent-like kinase 5 Homo sapiens (human)2.1
Cyclin homologHerpesvirus saimiri (strain 11)2.1
Lactoylglutathione lyaseHomo sapiens (human)3.2
Focal adhesion kinase 1Homo sapiens (human)1.2
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)3
ELAV-like protein 3Homo sapiens (human)1.8
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)2.1
ELAV-like protein 1Homo sapiens (human)1.4
Serine/threonine-protein kinase N1Homo sapiens (human)5.8
Mitogen-activated protein kinase 14Homo sapiens (human)2.88
Cytochrome P450 1B1Homo sapiens (human)1.1108
Probable maltase-glucoamylase 2Homo sapiens (human)7.8
Monocarboxylate transporter 2Rattus norvegicus (Norway rat)5
Integrase Human immunodeficiency virus 14.3
Casein kinase II subunit alpha 3Homo sapiens (human)0.55
Inositol polyphosphate multikinaseHomo sapiens (human)2.3
Aldo-keto reductase family 1 member C21Mus musculus (house mouse)6.9
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)1.8333
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)5.4
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)1.5
Aurora kinase BHomo sapiens (human)2.435
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)2.1
Serine/threonine-protein kinase Nek6Homo sapiens (human)4.23
NADPH oxidase 4Homo sapiens (human)0.68
Inositol hexakisphosphate kinase 2Homo sapiens (human)0.7
Short transient receptor potential channel 5Homo sapiens (human)6.5
ALK tyrosine kinase receptorHomo sapiens (human)3.32
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.25

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (13.04)29.6817
2010's16 (69.57)24.3611
2020's4 (17.39)2.80

Authors

AuthorsStudies
French, CJ; Hillhouse, BJ; Hudson, JB; López, A; Ming, DS; Towers, GH1
Amić, D; Lucić, B1
Bijak, M; Krotkiewski, H; Nowak, P; Pawlaczyk, I; Ponczek, M; Saluk, J; Wachowicz, B; Ziewiecki, R1
Chew, BP; Kaspar, KL; Khoo, C; Kimble, LL; Mathison, BD1
Oliveri, V1
Butterweck, V; Liefländer-Wulf, U; Nahrstedt, A; Winterhoff, H1
Hu, YC; Huang, XZ; Liu, Y; Qu, J; Yu, SS1
Ackermann, M; Hecker, D; Huemmer, W; Kahle, K; Kautenburger, T; Kempf, M; Richling, E; Scheppach, W; Schreier, P; Schrenk, D1
Anna Milella, R; Antonacci, D; Coletta, A; Crupi, P; Gasparro, M; Genghi, R; Perniola, R1
Bai, X; Ren, S; Zhang, H1
Gao, S; Hou, R; Liang, R; Wang, L; Yan, R; Yang, B; Zhang, J1
Allan, AC; Bovy, A; Butts, CA; Espley, RV; Hedderley, D; Hellens, RP; Laing, WA; Martell, S; McGhie, TK; Paturi, G; Putterill, J; Schouten, HJ; Smith, H; Zhang, J1
Gaivelyte, K; Jakstas, V; Janulis, V; Razukas, A1
Berregi, I; Dueñas, MT; Ostra, M; Puertas, AI; Zuriarrain, A; Zuriarrain, J1
Abbasi, AM; Fu, X; Guo, X; Liu, RH; Wen, L; You, L1
Hübner, F; Humpf, HU; Saenger, T1
Li, X; Shi, Q; Su, J; Zhang, Z; Zhou, J1
Deng, M; Deng, Y; Dong, L; Huang, F; Liu, L; Ma, Y; Wei, Z; Zhang, M; Zhang, R; Zhang, Y1
Busatto, N; Costa, F; Matsumoto, D; Tadiello, A; Vrhovsek, U1
Bondonno, CP; Bondonno, NP; Boyce, MC; Considine, MJ; Croft, KD; Hodgson, JM; Jacob, SR; Lacey, K; Shafaei, A; Shinde, S; Swinny, E; Woodman, RJ1
Dewettinck, K; Foubert, K; Muhammad, DRA; Patria, GD; Pieters, L; Tuenter, E1
Butkevičiūtė, A; Gelvonauskienė, D; Janulis, V; Kviklys, D; Liaudanskas, M1
Dellaire, G; Merlin, JPJ; Rupasinghe, HPV; Suraweera, TL; Xu, Z1

Reviews

1 review(s) available for procyanidin b2 and quercetin

ArticleYear
Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: alpha-Synuclein; Amyloidogenic Proteins; Drug Discovery; Humans; Protein Aggregation, Pathological; Structure-Activity Relationship

2019

Trials

2 trial(s) available for procyanidin b2 and quercetin

ArticleYear
Short-term biomarkers of apple consumption.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:3

    Topics: Adult; Biflavonoids; Biomarkers; Catechin; Chromatography, High Pressure Liquid; Female; Germany; Humans; Male; Malus; Phloretin; Proanthocyanidins; Quercetin; Reproducibility of Results; Tandem Mass Spectrometry

2017
Phenolic composition of 91 Australian apple varieties: towards understanding their health attributes.
    Food & function, 2020, Aug-19, Volume: 11, Issue:8

    Topics: Adult; Aged; Anthocyanins; Australia; Biflavonoids; Blood Glucose; Catechin; Chlorogenic Acid; Cholesterol; Cross-Over Studies; Female; Fruit; Humans; Male; Malus; Middle Aged; Phenols; Phlorhizin; Plant Extracts; Polyphenols; Proanthocyanidins; Quercetin; Waist Circumference; Young Adult

2020

Other Studies

20 other study(ies) available for procyanidin b2 and quercetin

ArticleYear
Bioactive constituents from Iryanthera megistophylla.
    Journal of natural products, 2002, Volume: 65, Issue:10

    Topics: Biological Factors; Myristicaceae; Spectrum Analysis

2002
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Thrombin inhibitory activity of some polyphenolic compounds.
    Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2014, Volume: 23

    Topics:

2014
Development of a fluorometric microplate antiadhesion assay using uropathogenic Escherichia coli and human uroepithelial cells.
    Journal of natural products, 2014, May-23, Volume: 77, Issue:5

    Topics: Bacterial Adhesion; Biflavonoids; Catechin; Epithelial Cells; Flavonoids; Fruit; Humans; Molecular Structure; Plant Extracts; Proanthocyanidins; Quercetin; Urine; Uropathogenic Escherichia coli; Vaccinium macrocarpon

2014
Plasma levels of hypericin in presence of procyanidin B2 and hyperoside: a pharmacokinetic study in rats.
    Planta medica, 2003, Volume: 69, Issue:3

    Topics: Administration, Oral; Animals; Anthracenes; Antidepressive Agents; Biflavonoids; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Drug Synergism; Male; Perylene; Phytotherapy; Plant Extracts; Proanthocyanidins; Quercetin; Rats; Rats, Sprague-Dawley; Solubility

2003
[Studies on chemical constituents from roots of Craibiodendron henryi].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:7

    Topics: Biflavonoids; Catechin; Ericaceae; Molecular Structure; Plant Roots; Plants, Medicinal; Proanthocyanidins; Quercetin; Sitosterols

2007
Intestinal transit and systemic metabolism of apple polyphenols.
    European journal of nutrition, 2011, Volume: 50, Issue:7

    Topics: Adult; Animals; Beverages; Biflavonoids; Caffeic Acids; Catechin; Chromatography, Gas; Chromatography, High Pressure Liquid; Coumaric Acids; Female; Gastrointestinal Transit; Hepatocytes; Humans; Ileostomy; Intestinal Mucosa; Male; Malus; Phloretin; Polyphenols; Proanthocyanidins; Quercetin; Quinic Acid; Rats; Rats, Wistar; Saliva; Tandem Mass Spectrometry; Young Adult

2011
HPLC-DAD-ESI-MS analysis of flavonoid compounds in 5 seedless table grapes grown in Apulian Region.
    Journal of food science, 2012, Volume: 77, Issue:2

    Topics: Anthocyanins; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Galactosides; Glucosides; Italy; Kaempferols; Linear Models; Monosaccharides; Proanthocyanidins; Quercetin; Vitis

2012
Antioxidant activity and HPLC analysis of polyphenol-enriched extracts from industrial apple pomace.
    Journal of the science of food and agriculture, 2013, Aug-15, Volume: 93, Issue:10

    Topics: Antioxidants; Benzothiazoles; Biflavonoids; Biphenyl Compounds; Catechin; Chlorogenic Acid; Chromatography, High Pressure Liquid; Food Industry; Fruit; Malus; Picrates; Plant Extracts; Polyphenols; Proanthocyanidins; Quercetin; Sulfonic Acids; Waste Products

2013
Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats.
    Journal of ethnopharmacology, 2013, Jul-09, Volume: 148, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Atherosclerosis; Biflavonoids; C-Reactive Protein; Catechin; Chlorogenic Acid; Crataegus; Diet, High-Fat; Drugs, Chinese Herbal; Endothelins; Fruit; Interleukins; Lipids; Male; Nitric Oxide; Plant Extracts; Proanthocyanidins; Quercetin; Random Allocation; Rats; Rats, Wistar; Rutin; Thromboxane B2; Water

2013
Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice.
    The Journal of nutrition, 2014, Volume: 144, Issue:2

    Topics: Animals; Anthocyanins; Bacteria; Biflavonoids; Biomarkers; Catechin; Colon; Diet; Dietary Supplements; Flavonoids; Food, Genetically Modified; Fruit; Genotype; Glycosides; Inflammation; Inflammation Mediators; Male; Malus; Mice; Mice, Inbred Strains; Microbiota; Phytotherapy; Plant Extracts; Plants, Genetically Modified; Proanthocyanidins; Quercetin; Reference Values; Transcription Factors; Transcription, Genetic; Transformation, Genetic

2014
Variation of quantitative composition of phenolic compounds in rowan (Sorbus aucuparia L.) leaves during the growth season.
    Natural product research, 2014, Volume: 28, Issue:13

    Topics: Antioxidants; Biflavonoids; Catechin; Chlorogenic Acid; Chromatography, High Pressure Liquid; Lithuania; Phenols; Plant Leaves; Proanthocyanidins; Quercetin; Seasons; Sorbus

2014
Polyphenolic profile in cider and antioxidant power.
    Journal of the science of food and agriculture, 2015, Volume: 95, Issue:14

    Topics: Animals; Antioxidants; Biflavonoids; Catechin; Coumaric Acids; Fermentation; Fruit; Fruit and Vegetable Juices; Humans; Malus; Phenylethyl Alcohol; Plant Extracts; Polyphenols; Proanthocyanidins; Propionates; Quercetin; Spain

2015
Phenolic contents and cellular antioxidant activity of Chinese hawthorn "Crataegus pinnatifida".
    Food chemistry, 2015, Nov-01, Volume: 186

    Topics: Antioxidants; Biflavonoids; Catechin; Chlorogenic Acid; Crataegus; Drug Evaluation, Preclinical; Flavonoids; Fruit; Glycosides; Hep G2 Cells; Humans; Oxidation-Reduction; Phenols; Plant Extracts; Proanthocyanidins; Quercetin

2015
Comparative Analysis of Pigments, Phenolics, and Antioxidant Activity of Chinese Jujube (
    Molecules (Basel, Switzerland), 2018, Aug-01, Volume: 23, Issue:8

    Topics: Anthocyanins; Antioxidants; Biflavonoids; Carotenoids; Catechin; Coumaric Acids; Phenols; Proanthocyanidins; Quercetin; Ziziphus

2018
Effect of Storage Conditions on Phenolic Profiles and Antioxidant Activity of Litchi Pericarp.
    Molecules (Basel, Switzerland), 2018, Sep-06, Volume: 23, Issue:9

    Topics: Antioxidants; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Fruit; Glucosides; Glycoside Hydrolases; Litchi; Phenols; Plant Extracts; Proanthocyanidins; Quercetin

2018
Multifaceted analyses disclose the role of fruit size and skin-russeting in the accumulation pattern of phenolic compounds in apple.
    PloS one, 2019, Volume: 14, Issue:7

    Topics: Antioxidants; Biflavonoids; Catechin; Fruit; Gene Expression Profiling; Gene Expression Regulation, Plant; Malus; Phenols; Phlorhizin; Phytochemicals; Principal Component Analysis; Proanthocyanidins; Quercetin

2019
Phytochemical composition and antioxidant activity of Cinnamomum burmannii Blume extracts and their potential application in white chocolate.
    Food chemistry, 2021, Mar-15, Volume: 340

    Topics: Antioxidants; Biflavonoids; Catechin; Chocolate; Cinnamomum zeylanicum; Cryoelectron Microscopy; Food-Processing Industry; Hydroxybenzoates; Phenols; Phytochemicals; Plant Extracts; Proanthocyanidins; Quercetin; Ultrasonics

2021
The Qualitative and Quantitative Compositions of Phenolic Compounds in Fruits of Lithuanian Heirloom Apple Cultivars.
    Molecules (Basel, Switzerland), 2020, Nov-11, Volume: 25, Issue:22

    Topics: Biflavonoids; Catechin; Chlorogenic Acid; Chromatography, High Pressure Liquid; Dietary Supplements; Flavonoids; Fruit; Glycosides; Lithuania; Malus; Phenols; Phlorhizin; Proanthocyanidins; Quercetin; Rutin

2020
Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro.
    International journal of molecular sciences, 2023, Feb-12, Volume: 24, Issue:4

    Topics: Antioxidant Response Elements; Carcinogens; DNA Damage; Epithelial Cells; Flavonoids; Genistein; Humans; NF-E2-Related Factor 2; Oxidative Stress; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Quercetin; Reactive Oxygen Species; Signal Transduction

2023