Page last updated: 2024-09-02

procyanidin and epigallocatechin gallate

procyanidin has been researched along with epigallocatechin gallate in 50 studies

Compound Research Comparison

Studies
(procyanidin)
Trials
(procyanidin)
Recent Studies (post-2010)
(procyanidin)
Studies
(epigallocatechin gallate)
Trials
(epigallocatechin gallate)
Recent Studies (post-2010) (epigallocatechin gallate)
4,1161362,7475,4561733,403

Protein Interaction Comparison

ProteinTaxonomyprocyanidin (IC50)epigallocatechin gallate (IC50)
Chain A, POLYMERASE PAInfluenza A virus1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Prostaglandin E synthaseHomo sapiens (human)1.8
Telomerase reverse transcriptaseHomo sapiens (human)1.0867
NAD kinaseHomo sapiens (human)0.96
Urokinase-type plasminogen activatorHomo sapiens (human)0.091
Tissue-type plasminogen activatorHomo sapiens (human)0.091
Polymerase acidic proteinInfluenza A virus (A/Puerto Rico/8/1934(H1N1))5.86
Amyloid-beta precursor proteinHomo sapiens (human)2.7
Plasminogen activator inhibitor 1Homo sapiens (human)0.091
Urokinase-type plasminogen activatorMus musculus (house mouse)0.091
ATP-dependent translocase ABCB1Homo sapiens (human)0.1233
72 kDa type IV collagenaseHomo sapiens (human)4.3833
Hepatocyte growth factor receptorHomo sapiens (human)10
MatrilysinHomo sapiens (human)3.34
Enoyl-[acyl-carrier-protein] reductase [NADH] FabIEscherichia coli K-125
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 21.15
Apoptosis regulator Bcl-2Homo sapiens (human)0.45
Microtubule-associated protein tauHomo sapiens (human)1.8
60 kDa heat shock protein, mitochondrialHomo sapiens (human)2.3
Glucose-6-phosphate 1-dehydrogenaseSaccharomyces cerevisiae S288C0.25
Lethal factorBacillus anthracis0.097
Phosphoglycerate mutase 1Homo sapiens (human)0.49
DNA (cytosine-5)-methyltransferase 1Homo sapiens (human)0.5
Proteasome subunit beta type-5Homo sapiens (human)0.543
DNA repair protein RAD52 homologHomo sapiens (human)2.5108
Matrix metalloproteinase-14Homo sapiens (human)6.8
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6Homo sapiens (human)3.34
Squalene monooxygenase Rattus norvegicus (Norway rat)0.69
6-phosphogluconate dehydrogenase, decarboxylatingHomo sapiens (human)0.72
BH3-interacting domain death agonistHomo sapiens (human)1.0733
Beta-secretase 1Homo sapiens (human)1.1785
10 kDa heat shock protein, mitochondrialHomo sapiens (human)2.3
Bcl-2-like protein 1Homo sapiens (human)0.59
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)0.92
Alpha-(1,3)-fucosyltransferase 7Homo sapiens (human)3.34
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1Homo sapiens (human)3.34
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.3055
Mitogen-activated protein kinase 14Homo sapiens (human)2.21
Bcl-2-related protein A1Homo sapiens (human)1.79
Thiosulfate sulfurtransferaseHomo sapiens (human)7.3
60 kDa chaperonin Escherichia coli0.47
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)10
Dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)0.33
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.73
10 kDa chaperonin Escherichia coli0.47
3-oxoacyl-[acyl-carrier-protein] reductase Plasmodium falciparum 3D70.32
MAP kinase-activated protein kinase 5Homo sapiens (human)1
Bcl-2-like protein 2Homo sapiens (human)2.33
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)0.225
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)0.3
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)0.215
Bcl-2-like protein 10Homo sapiens (human)0.36

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (22.00)29.6817
2010's31 (62.00)24.3611
2020's8 (16.00)2.80

Authors

AuthorsStudies
Aldini, G; Bombardelli, E; Carini, M; Maffei Facino, R; Morazzoni, P1
Bors, W; Foo, LY; Hertkorn, N; Michel, C; Stettmaier, K1
Hatano, T; Ito, H; Itoh, Y; Kobayashi, E; Kubo, N; Li, SH; Nishino, H; Shimura, S; Sugita, D; Tokuda, H; Yoshida, T1
Nakazawa, H; Yamaguchi, F; Yoshimura, Y1
Hamada, H; Iigo, M; Kojima, S; Nomoto, H; Tsuda, H1
Chen, Y; Hagerman, AE1
Amano, A; Inaba, H; Kanda, T; Kawai, S; Ohno, T; Tagashira, M1
Aruoma, OI; Bahorun, T; Crozier, A; Datla, KP; Dexter, DT; Luximon-Ramma, A; Neergheen, VS; Zbarsky, V1
Cabane, B; Pascal, C; Poncet-Legrand, C; Vernhet, A1
Humpf, HU; van't Slot, G1
Grace, MH; Kurmukov, AG; Lila, MA; Raskin, I; Yousef, GG1
Ardèvol, A; Arola, L; Bladé, C; Blay, M; Bustos, M; Fernández-Larrea, J; Pujadas, G; Quesada, IM; Salvadó, MJ1
Alegre, L; Hernández, I; Munné-Bosch, S1
Bravo, L; Goya, L; Martín, MA; Ramos, S; Rodríguez-Ramiro, I1
Chen, J; Liu, D; Shen, Y; Yang, H; Ye, X; Yu, D; Zhang, J1
Ardevol, A; Arola, L; Blade, C; Blay, MT; Fernandez-Larrea, J; Palozza, P; Pujadas, G; Salvado, J; Terra, X1
Arola-Arnal, A; Bladé, C1
Hisamura, M; Kanetaka, T; Koga, K; Matsuo, Y; Tanaka, T; Yoshino, K1
Gao, JM; Gu, L; Liu, H; Zou, T1
Doi, S; Harui, K; Higashino, Y; Ishihara, S; Kawasaki, T; Nakajima, N; Okamoto, S; Okamoto, T; Saito, A1
Tong, LX; Young, LC1
Bazzoli, F; Belluzzi, A; Bianchi, F; D'Angelo, L; Fazio, C; Fogliano, V; Graziani, G; Montanaro, L; Munarini, A; Pacilli, A; Piazzi, G; Prossomariti, A; Ricciardiello, L1
Alexeev, Y; Cerezo, AB; Hollands, WJ; Kroon, PA; Moyle, CW; Needs, PW; Winterbone, MS1
Grenier, D; Lombardo Bedran, TB; Palomari Spolidorio, D1
Deb, M; Kar, S; Parbin, S; Patra, SK; Pradhan, N; Rakshit, M; Rath, SK; Sengupta, D; Shilpi, A1
Bai, X; Keightley, A; Li, S; Liu, Y; Wang, Y1
Khan, M; Ma, T; Maryam, A; Mehmood, T; Zhang, Y1
Cooley, A; Elder, S; Liao, J; Pinheiro, A; Prabhu, R1
Carbonara, M; Cassano, N; Gurioli, C; Neri, I; Patrizi, A; Raone, B; Vena, GA1
Mueller-Harvey, I; Ramsay, A; Thamsborg, SM; Williams, AR1
Berndt, C; Briggs, JM; Britt, CB; Burress, H; Cherubin, P; Craft, JW; Curtis, D; Garcia, MC; Guyette, J; Huo, Q; Quiñones, B; Reddy, S; Teter, K; Zheng, T1
Katiyar, SK1
de Oliveira Caleare, A; Hensel, A; Lechtenberg, M; Mello, JC; Nakamura, CV; Panizzon, GP; Petereit, F; Pinha, AB1
Saito, A1
Bao, J; Gordon, RE; Karalis, G; Karthikeyan, L; Lipson, SM; Ozen, FS; Ponnala, S; Samarrai, W; Wolfe, E1
Khalifa, I; Li, C; Peng, J; Zhu, W1
Dhanani, T; Kumar, S; Singh, R1
Aoki, S; Masumoto, S; Miura, T; Shoji, T1
Chen, M; Dai, W; Guo, L; Hu, Z; Li, P; Lin, Z; Lu, M; Lv, H; Peng, Q; Tan, J; Yang, C; Zhang, Y; Zhu, Y1
Yi, YS1
Ashokkumar, R; Devaraj, SN; Jamuna, S; Sakeena Sadullah, MS1
Blanchard, C; Liu, J; Liu, Y; Meng, D; Yang, R; Zhang, Y; Zhou, Z1
Cao, Y; Chen, S; Shen, S; Tao, W; Wang, M; Wei, C; Ye, X1
da Silva Campelo Borges, G; Dantas, AM; de Lima Oliveira, PM; Dos Santos Lima, M; Dos Santos Morais, AR; Gibbert, L; Krüger, CCH; Magnani, M1
Chen, S; Mao, G; Pan, H; Shen, X; Tao, W; Wu, W; Ye, X; Zhou, S1
Celichowski, G; Cymerys, J; Grobelny, J; Krzyzowska, M; Orlowski, P; Pajak, B; Ranoszek-Soliwoda, K; Slonska, A; Tomaszewska, E; Zmigrodzka, M1
Farias-Neto, AM; Francisconi-Dos-Rios, LF; Honório, HM; Landmayer, K; Liberatti, GA; Wang, L1
Chen, Y; Jiang, C; Jing, H; Ma, C; Shao, J; Wang, H; Wang, L; Ye, X1
Gao, Y; Guan, YQ; He, J; Jiang, S; Wang, X; Yin, L; You, R; Zhang, LK1
Oteiza, PI; Zhu, W1

Reviews

6 review(s) available for procyanidin and epigallocatechin gallate

ArticleYear
Nutrition: the future of melanoma prevention?
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:1

    Topics: Antioxidants; Carotenoids; Catechin; Diet; Grape Seed Extract; Humans; Lycopene; Melanoma; Nutrition Policy; Proanthocyanidins; Resveratrol; Selenium; Skin Neoplasms; Stilbenes; Vitamin D; Vitamin E

2014
Enhancing Activity of Anticancer Drugs in Multidrug Resistant Tumors by Modulating P-Glycoprotein through Dietary Nutraceuticals.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:16

    Topics: Abietanes; Alkaloids; Allyl Compounds; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Benzodioxoles; beta Carotene; Biflavonoids; Capsaicin; Catechin; Catechols; Curcumin; Dietary Supplements; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Fatty Alcohols; Furocoumarins; Humans; Indoles; Limonins; Neoplasms; Phytotherapy; Piperidines; Polyunsaturated Alkamides; Proanthocyanidins; Quercetin; Resveratrol; Stilbenes; Sulfides; Tea; Triterpenes; Xanthophylls

2015
Emerging Phytochemicals for the Prevention and Treatment of Head and Neck Cancer.
    Molecules (Basel, Switzerland), 2016, Nov-24, Volume: 21, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Evaluation, Preclinical; Head and Neck Neoplasms; Humans; Lignans; Magnolia; Polyphenols; Proanthocyanidins; Squamous Cell Carcinoma of Head and Neck; Tea; Vitis

2016
Challenges and complexity of functionality evaluation of flavan-3-ol derivatives.
    Bioscience, biotechnology, and biochemistry, 2017, Volume: 81, Issue:6

    Topics: Catechin; Flavonoids; Functional Food; Health Promotion; Humans; Molecular Structure; Polyphenols; Proanthocyanidins; Structure-Activity Relationship; Tea

2017
Regulatory Roles of Flavonoids on Inflammasome Activation during Inflammatory Responses.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:13

    Topics: Animals; Apigenin; Biflavonoids; Catechin; Chalcones; Drug Development; Flavonoids; Humans; Inflammasomes; Inflammation; Luteolin; Proanthocyanidins; Quercetin; Rutin

2018
Fabrication, structure, and function evaluation of the ferritin based nano-carrier for food bioactive compounds.
    Food chemistry, 2019, Nov-30, Volume: 299

    Topics: Anthocyanins; beta Carotene; Biological Availability; Catechin; Chitosan; Curcumin; Ferritins; Food; Humans; Nanostructures; Polyphenols; Proanthocyanidins; Solubility

2019

Trials

1 trial(s) available for procyanidin and epigallocatechin gallate

ArticleYear
Randomized, controlled, double-blind clinical study evaluating the safety and efficacy of MD2011001 cream in mild-to-moderate atopic dermatitis of the face and neck in children, adolescents and adults.
    The Journal of dermatological treatment, 2016, Volume: 27, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Catechin; Child; Child, Preschool; Dermatitis, Atopic; Double-Blind Method; Emollients; Face; Female; Grape Seed Extract; Humans; Male; Neck; Proanthocyanidins; Treatment Outcome; Vitamin E; Young Adult

2016

Other Studies

43 other study(ies) available for procyanidin and epigallocatechin gallate

ArticleYear
UVB-induced hemolysis of rat erythrocytes: protective effect of procyanidins from grape seeds.
    Life sciences, 2000, Sep-01, Volume: 67, Issue:15

    Topics: Animals; Antioxidants; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Glutathione; Hemoglobins; Hemolysis; Lipid Peroxidation; Male; Membrane Fluidity; Oxidants; Oxidation-Reduction; Phospholipids; Proanthocyanidins; Rats; Rats, Wistar; Rosales; Thiobarbituric Acid Reactive Substances; Ultraviolet Rays; Vitamin E

2000
Chemical studies of proanthocyanidins and hydrolyzable tannins.
    Antioxidants & redox signaling, 2001, Volume: 3, Issue:6

    Topics: Anthocyanins; Antioxidants; Catechin; Dimerization; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydrolysis; Hydrolyzable Tannins; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Oxygen; Phenol; Proanthocyanidins; Tannins; Time Factors

2001
Antitumor activity of compounds isolated from leaves of Eriobotrya japonica.
    Journal of agricultural and food chemistry, 2002, Apr-10, Volume: 50, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Biflavonoids; Carcinogens; Catechin; Female; Glucosides; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Nasopharyngeal Neoplasms; Norisoprenoids; Peroxynitrous Acid; Plant Leaves; Proanthocyanidins; Rosaceae; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Virus Activation

2002
Evaluation of the NO scavenging activity of procyanidin in grape seed by use of the TMA-PTIO/NOC 7 ESR system.
    Journal of agricultural and food chemistry, 2003, Oct-22, Volume: 51, Issue:22

    Topics: Biflavonoids; Catechin; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Nitric Oxide; Proanthocyanidins; Seeds; Vitis

2003
Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis.
    Nutrition and cancer, 2004, Volume: 49, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Biflavonoids; Carcinogens; Caspase 3; Caspases; Catechin; Cell Division; Colorectal Neoplasms; Immunohistochemistry; Male; Proanthocyanidins; Random Allocation; Rats; Rats, Inbred F344

2004
Reaction pH and protein affect the oxidation products of beta-pentagalloyl glucose.
    Free radical research, 2005, Volume: 39, Issue:2

    Topics: Biflavonoids; Catechin; Free Radicals; Hydrogen-Ion Concentration; Hydrolyzable Tannins; Molecular Conformation; Oxidation-Reduction; Periodic Acid; Proanthocyanidins; Quinones; Serum Albumin, Bovine; Zinc

2005
Apple- and hop-polyphenols protect periodontal ligament cells stimulated with enamel matrix derivative from Porphyromonas gingivalis.
    Journal of periodontology, 2005, Volume: 76, Issue:12

    Topics: Adhesins, Bacterial; Catechin; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dental Enamel Proteins; Flavonoids; Gingipain Cysteine Endopeptidases; Humans; Humulus; Malus; Periodontal Ligament; Phenols; Polyphenols; Porphyromonas gingivalis; Proanthocyanidins; Protease Inhibitors; Urokinase-Type Plasminogen Activator

2005
Assessment of the polyphenolic composition of the organic extracts of Mauritian black teas: a potential contributor to their antioxidant functions.
    BioFactors (Oxford, England), 2006, Volume: 27, Issue:1-4

    Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Flavonols; Gallic Acid; Oxidation-Reduction; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Tea

2006
Aggregation of a proline-rich protein induced by epigallocatechin gallate and condensed tannins: effect of protein glycosylation.
    Journal of agricultural and food chemistry, 2008, Aug-13, Volume: 56, Issue:15

    Topics: Catechin; Colloids; Drug Stability; Glycosylation; Humans; Light; Proanthocyanidins; Proline; Salivary Proteins and Peptides; Scattering, Radiation; Seeds; Solutions; Vitis; X-Rays

2008
Degradation and metabolism of catechin, epigallocatechin-3-gallate (EGCG), and related compounds by the intestinal microbiota in the pig cecum model.
    Journal of agricultural and food chemistry, 2009, Sep-09, Volume: 57, Issue:17

    Topics: Animals; Bacteria; Catechin; Cecum; Flavonoids; Models, Biological; Proanthocyanidins; Stereoisomerism; Swine

2009
Phytochemical characterization of an adaptogenic preparation from Rhodiola heterodonta.
    Natural product communications, 2009, Volume: 4, Issue:8

    Topics: Animals; Catechin; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Liquid; Ethanol; Glucosides; Hypoxia; Mass Spectrometry; Mice; Phenols; Phenylethyl Alcohol; Plant Preparations; Proanthocyanidins; Rhodiola

2009
Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells.
    The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:2

    Topics: Biflavonoids; Carcinoma, Hepatocellular; Catechin; Cation Transport Proteins; Diet; Gene Expression Regulation; Grape Seed Extract; Hep G2 Cells; Homeostasis; Humans; Interleukin-6; Liver Neoplasms; Metallothionein; Proanthocyanidins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tea; Zinc

2011
Plant aging and excess light enhance flavan-3-ol content in Cistus clusii.
    Journal of plant physiology, 2011, Jan-15, Volume: 168, Issue:2

    Topics: Catechin; Cellular Senescence; Cistus; Flavonoids; Light; Lipid Peroxidation; Proanthocyanidins

2011
Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells.
    European journal of nutrition, 2011, Volume: 50, Issue:5

    Topics: Antioxidants; Biflavonoids; Caco-2 Cells; Caspase 3; Catechin; Cell Survival; Diet; Glutathione; Glutathione Peroxidase; Humans; Oxidative Stress; Proanthocyanidins; Reactive Oxygen Species

2011
Characterization of unusual proanthocyanidins in leaves of bayberry ( Myrica rubra Sieb. et Zucc.).
    Journal of agricultural and food chemistry, 2011, Mar-09, Volume: 59, Issue:5

    Topics: Catechin; Chromatography, High Pressure Liquid; Myrica; Phenols; Phloroglucinol; Plant Leaves; Proanthocyanidins

2011
Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes.
    Free radical research, 2011, Volume: 45, Issue:5

    Topics: Antioxidants; Biflavonoids; Catechin; Cell Line; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Free Radicals; Humans; I-kappa B Kinase; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Monocytes; NF-kappa B; Phosphorylation; Proanthocyanidins; Reactive Oxygen Species; Signal Transduction

2011
Proanthocyanidins modulate microRNA expression in human HepG2 cells.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Catechin; Computational Biology; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Insulin; Lipid Metabolism; MicroRNAs; Oxidative Stress; Proanthocyanidins; Reproducibility of Results; Signal Transduction; Transcriptome

2011
Proanthocyanidin oligomers isolated from Salacia reticulata leaves potently inhibit pancreatic lipase activity.
    Journal of food science, 2013, Volume: 78, Issue:1

    Topics: Catechin; Inhibitory Concentration 50; Lipase; Pancreas; Plant Leaves; Plant Stems; Polyphenols; Proanthocyanidins; Salacia; Tea

2013
Depolymerization of cranberry procyanidins using (+)-catechin, (-)-epicatechin, and (-)-epigallocatechin gallate as chain breakers.
    Food chemistry, 2013, Nov-01, Volume: 141, Issue:1

    Topics: Catechin; Plant Extracts; Polymerization; Proanthocyanidins; Vaccinium macrocarpon

2013
Inhibitory activity of synthesized acetylated Procyanidin B1 analogs against HeLa S3 cells proliferation.
    Molecules (Basel, Switzerland), 2014, Feb-04, Volume: 19, Issue:2

    Topics: Acetylation; Biflavonoids; Catechin; Cell Proliferation; HeLa Cells; Humans; Neoplasms; Polymers; Proanthocyanidins; Tea

2014
A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells.
    Carcinogenesis, 2014, Volume: 35, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Eicosapentaenoic Acid; Grape Seed Extract; Humans; Proanthocyanidins; Proto-Oncogene Proteins c-myc; Signal Transduction; TOR Serine-Threonine Kinases

2014
Potent inhibition of VEGFR-2 activation by tight binding of green tea epigallocatechin gallate and apple procyanidins to VEGF: relevance to angiogenesis.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:3

    Topics: Biflavonoids; Binding Sites; Catechin; Computer Simulation; Human Umbilical Vein Endothelial Cells; Humans; Malus; Phosphorylation; Proanthocyanidins; Signal Transduction; Tea; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2015
Green tea polyphenol epigallocatechin-3-gallate and cranberry proanthocyanidins act in synergy with cathelicidin (LL-37) to reduce the LPS-induced inflammatory response in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts.
    Archives of oral biology, 2015, Volume: 60, Issue:6

    Topics: Aggregatibacter actinomycetemcomitans; Antimicrobial Cationic Peptides; Catechin; Cathelicidins; Coculture Techniques; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblasts; Gingiva; Humans; Inflammation Mediators; Lipopolysaccharides; Plant Extracts; Proanthocyanidins; Tea; Vaccinium macrocarpon

2015
Mechanisms of DNA methyltransferase-inhibitor interactions: Procyanidin B2 shows new promise for therapeutic intervention of cancer.
    Chemico-biological interactions, 2015, May-25, Volume: 233

    Topics: Amino Acid Sequence; Animals; Biflavonoids; Breast; Breast Neoplasms; Catechin; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Humans; Mice; Molecular Docking Simulation; Molecular Sequence Data; Proanthocyanidins; Sequence Alignment

2015
Molecular weight and galloylation affect grape seed extract constituents' ability to cross-link dentin collagen in clinically relevant time.
    Dental materials : official publication of the Academy of Dental Materials, 2015, Volume: 31, Issue:7

    Topics: Biflavonoids; Catechin; Collagen; Cross-Linking Reagents; Dentin; Grape Seed Extract; Humans; In Vitro Techniques; Mass Spectrometry; Materials Testing; Molar; Molecular Structure; Molecular Weight; Polymerization; Proanthocyanidins; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tensile Strength; Time Factors

2015
Comparison of natural crosslinking agents for the stabilization of xenogenic articular cartilage.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2016, Volume: 34, Issue:6

    Topics: Animals; Cartilage; Cartilage, Articular; Catechin; Collagenases; Cross-Linking Reagents; Drug Evaluation, Preclinical; Grape Seed Extract; Heterografts; Iridoids; Proanthocyanidins; Swine

2016
Galloylated proanthocyanidins from shea (Vitellaria paradoxa) meal have potent anthelmintic activity against Ascaris suum.
    Phytochemistry, 2016, Volume: 122

    Topics: Animals; Anthelmintics; Ascaris suum; Catechin; Chromatography, High Pressure Liquid; Ericaceae; Flavonoids; Gallic Acid; Molecular Structure; Proanthocyanidins; Seeds; Swine

2016
Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: ADP Ribose Transferases; Animals; Bacterial Toxins; Biflavonoids; Binding Sites; Catechin; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; CHO Cells; Cholera Toxin; Cricetulus; Diphtheria Toxin; Exotoxins; Fruit; Grape Seed Extract; Molecular Docking Simulation; Phenols; Plant Extracts; Proanthocyanidins; Pseudomonas aeruginosa Exotoxin A; Ricin; Vero Cells; Virulence Factors; Vitis

2016
Flavan-3-ols and proanthocyanidins from Limonium brasiliense inhibit the adhesion of Porphyromonas gingivalis to epithelial host cells by interaction with gingipains.
    Fitoterapia, 2017, Volume: 118

    Topics: Adhesins, Bacterial; Bacterial Adhesion; Benzopyrans; Catechin; Cysteine Endopeptidases; Epithelial Cells; Flavonoids; Gallic Acid; Gingipain Cysteine Endopeptidases; Humans; KB Cells; Plant Extracts; Plumbaginaceae; Porphyromonas gingivalis; Proanthocyanidins; Rhizome

2017
Mechanism of Anti-rotavirus Synergistic Activity by Epigallocatechin Gallate and a Proanthocyanidin-Containing Nutraceutical.
    Food and environmental virology, 2017, Volume: 9, Issue:4

    Topics: Antiviral Agents; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Drug Synergism; Mass Spectrometry; Phytochemicals; Plant Extracts; Proanthocyanidins; Rotavirus; Vaccinium macrocarpon

2017
Position and orientation of gallated proanthocyanidins in lipid bilayer membranes: influence of polymerization degree and linkage type.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:11

    Topics: Algorithms; Catechin; Hydrogen Bonding; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Proanthocyanidins

2018
Extraction optimization of gallic acid, (+)-catechin, procyanidin-B2, (-)-epicatechin, (-)-epigallocatechin gallate, and (-)-epicatechin gallate: their simultaneous identification and quantification in Saraca asoca.
    Journal of food and drug analysis, 2017, Volume: 25, Issue:3

    Topics: Catechin; Chromatography, High Pressure Liquid; Fabaceae; Gallic Acid; Proanthocyanidins; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry

2017
Flavan-3-ol/Procyanidin Metabolomics in Rat Urine Using HPLC-Quadrupole TOF/MS.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:19

    Topics: Animals; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Male; Mass Spectrometry; Molecular Weight; Proanthocyanidins; Rats, Wistar

2018
Application of metabolomics profiling in the analysis of metabolites and taste quality in different subtypes of white tea.
    Food research international (Ottawa, Ont.), 2018, Volume: 106

    Topics: Amino Acids; Astringents; Benzopyrans; Biflavonoids; Caffeine; Catechin; Flavones; Flavonoids; Flavonols; Gallic Acid; Glycosides; Hydroxybenzoates; Metabolomics; Odorants; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Quinic Acid; Taste; Tea

2018
Oligomeric proanthocyanidins and epigallocatechin gallate aggravate autophagy of foam cells through the activation of Class III PI3K/Beclin1-complex mediated cholesterol efflux.
    BioFactors (Oxford, England), 2019, Volume: 45, Issue:5

    Topics: ATP Binding Cassette Transporter 1; Autophagy; Autophagy-Related Protein 5; Beclin-1; Catechin; Cholesterol; Chromones; Class III Phosphatidylinositol 3-Kinases; Enzyme Inhibitors; Foam Cells; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Morpholines; Phagosomes; Proanthocyanidins; Protein Isoforms; Proto-Oncogene Proteins c-akt; Signal Transduction; THP-1 Cells; TOR Serine-Threonine Kinases

2019
Mainly Dimers and Trimers of Chinese Bayberry Leaves Proanthocyanidins (BLPs) are Utilized by Gut Microbiota: In Vitro Digestion and Fermentation Coupled with Caco-2 Transportation.
    Molecules (Basel, Switzerland), 2020, Jan-01, Volume: 25, Issue:1

    Topics: Biological Availability; Biopolymers; Caco-2 Cells; Catechin; Digestion; Fermentation; Gallic Acid; Gastric Mucosa; Gastrointestinal Microbiome; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intestines; Myrica; Plant Leaves; Polymerization; Proanthocyanidins; Saliva

2020
Juá fruit (Ziziphus joazeiro) from Caatinga: A source of dietary fiber and bioaccessible flavanols.
    Food research international (Ottawa, Ont.), 2020, Volume: 129

    Topics: Antioxidants; Biflavonoids; Brazil; Catechin; Chemical Phenomena; Dietary Fiber; Fruit; Nutritive Value; Phytochemicals; Plant Extracts; Polyphenols; Proanthocyanidins; Ziziphus

2020
Preparation of a novel emulsifier by self-assembling of proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves with gelatin.
    Food chemistry, 2020, Jul-30, Volume: 319

    Topics: Catechin; Emulsifying Agents; Emulsions; Fruit; Gelatin; Myrica; Plant Leaves; Proanthocyanidins

2020
Polyphenol-Conjugated Bimetallic Au@AgNPs for Improved Wound Healing.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antioxidants; Biflavonoids; Catechin; Gold; Metal Nanoparticles; Mice; Polyphenols; Proanthocyanidins; Silver; Tannins; Wound Healing

2020
Could applying gels containing chlorhexidine, epigallocatechin-3-gallate, or proanthocyanidin to control tooth wear progression improve bond strength to eroded dentin?
    The Journal of prosthetic dentistry, 2020, Volume: 124, Issue:6

    Topics: Catechin; Chlorhexidine; Composite Resins; Dental Bonding; Dentin; Dentin-Bonding Agents; Gels; Humans; Materials Testing; Proanthocyanidins; Resin Cements; Tensile Strength; Tooth Wear

2020
Three flavanols delay starch digestion by inhibiting α-amylase and binding with starch.
    International journal of biological macromolecules, 2021, Mar-01, Volume: 172

    Topics: alpha-Amylases; Biflavonoids; Binding Sites; Catechin; Glucose; Glycoside Hydrolase Inhibitors; Hydrolysis; Kinetics; Maltose; Molecular Docking Simulation; Proanthocyanidins; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Starch; Substrate Specificity; Thermodynamics; Trisaccharides

2021
Multi-ligand modified PC@DOX-PA/EGCG micelles effectively inhibit the growth of ER
    Journal of materials chemistry. B, 2022, 01-19, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biflavonoids; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Carriers; Drug Liberation; Humans; Ligands; Mice, Inbred BALB C; Micelles; Phosphatidylcholines; Proanthocyanidins

2022
NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion.
    Redox biology, 2023, Volume: 65

    Topics: Caco-2 Cells; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Electrocardiography; Epidermal Growth Factor; ErbB Receptors; Humans; Matrix Metalloproteinase 2; NADPH Oxidase 1; Neoplasm Invasiveness; Proanthocyanidins

2023