Page last updated: 2024-09-02

procyanidin and dinoprostone

procyanidin has been researched along with dinoprostone in 22 studies

Compound Research Comparison

Studies
(procyanidin)
Trials
(procyanidin)
Recent Studies (post-2010)
(procyanidin)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
4,1161362,74729,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomyprocyanidin (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's7 (31.82)29.6817
2010's12 (54.55)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Heinrich, M; Hör, M; Rimpler, H1
Arakawa, Y; Iwasaki, Y; Matsui, T1
Bodet, C; Chandad, F; Grenier, D1
Fujii, M; Hashimoto, F; Hou, DX; Masuzaki, S; Sakata, Y; Tanigawa, S; Uto, T1
Ho, SC; Hwang, LS; Lin, CC; Shen, YJ1
Choi, HK; Choi, SE; Kim, HJ; Kim, SK; Lee, MW; Park, KH1
Andrade, FD; Cola, MM; Feitosa, SB; Hiruma-Lima, CA; Kushima, H; Lolis, Sde F; Magri, LP; Moraes, TM; Rodrigues, CM; Soares, FR; Souza Brito, AR; Vilegas, W1
Katiyar, SK; Meeran, SM; Punathil, T; Vaid, M1
Chi, CW; Huang, PL; Liu, TY1
Katiyar, SK; Sharma, SD1
Katiyar, SK; Meeran, SM; Sharma, SD1
Choi, SE; Han, BH; Jeong, MS; Joo, SS; Lee, DI; Lee, MW; Park, KH; Seo, SJ1
Katiyar, SK; Singh, T; Vaid, M1
Ardèvol, A; Blay, M; González-Abuín, N; Martinez-Micaelo, N; Pinent, M; Richart, C; Terra, X1
Byun, EB; Byun, EH; Byun, MW; Kim, JH; Kim, JK; Lee, JW; Park, JH; Park, SH; Song, BS; Song, DS; Sung, NY1
Jung, E; Kim, EG; Kim, JH; Kim, S; Lee, J; Park, D; Shin, SW1
Bak, MJ; Jeong, WS; Jun, M; Kang, HS; Truong, VL1
Chien, TY; Huang, GC; Lee, CJ; Tseng, SH; Wang, CC; Wang, KT; Weng, BC1
Delvin, E; Denis, MC; Desjardins, Y; Dudonné, S; Furtos, A; Garofalo, C; Levy, E; Marcil, V; Marette, A; Montoudis, A1
Abadie, J; Beck, L; Gauthier, O; Guicheux, J; Hivernaud, V; Houard, X; Krisa, S; Lesoeur, J; Masson, M; Merceron, C; Mével, E; Nourissat, G; Richard, T; Urban, N; Vinatier, C; Wittrant, Y1
Dong, B; Feng, J; Gao, H; Han, S; Li, JX; Li, XX; Tang, M; Wang, QQ; Yang, S; Yuan, R; Zhao, LC1
Jiang, M; Jiao, JY; Li, Y; Lian, LH; Lin, YC; Liu, J; Nan, JX; Piao, MH; Qiao, CY; Shang, Y; Sun, RH; Wu, YL; Ye, H; Zhan, ZY; Zhang, ZH1

Other Studies

22 other study(ies) available for procyanidin and dinoprostone

ArticleYear
Inhibition of intestinal chloride secretion by proanthocyanidins from Guazuma ulmifolia.
    Planta medica, 1995, Volume: 61, Issue:3

    Topics: Animals; Anthocyanins; Chlorides; Cholera Toxin; Colon; Dinoprostone; In Vitro Techniques; Intestinal Mucosa; Plants, Medicinal; Proanthocyanidins; Rabbits

1995
The protective and hormonal effects of proanthocyanidin against gastric mucosal injury in Wistar rats.
    Journal of gastroenterology, 2004, Volume: 39, Issue:9

    Topics: Animals; Antioxidants; Dinoprostone; Gastric Mucosa; Gastrins; Histamine; In Vitro Techniques; Male; Peroxidase; Proanthocyanidins; Rats; Rats, Wistar; Somatostatin; Superoxide Dismutase

2004
Cranberry components inhibit interleukin-6, interleukin-8, and prostaglandin E production by lipopolysaccharide-activated gingival fibroblasts.
    European journal of oral sciences, 2007, Volume: 115, Issue:1

    Topics: Cells, Cultured; Cyclooxygenase 2 Inhibitors; Dinoprostone; Fibroblasts; Gingiva; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Plant Extracts; Proanthocyanidins; Vaccinium macrocarpon

2007
Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages: molecular mechanisms and structure-activity relationship.
    Archives of biochemistry and biophysics, 2007, Apr-01, Volume: 460, Issue:1

    Topics: Animals; Anthocyanins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Proanthocyanidins; Signal Transduction; Structure-Activity Relationship

2007
Suppressive effect of a proanthocyanidin-rich extract from longan (Dimocarpus longan Lour.) flowers on nitric oxide production in LPS-stimulated macrophage cells.
    Journal of agricultural and food chemistry, 2007, Dec-26, Volume: 55, Issue:26

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Dinoprostone; Flowers; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Proanthocyanidins; Sapindaceae

2007
Anti-oxidative and inhibitory activities on nitric oxide (NO) and prostaglandin E2 (COX-2) production of flavonoids from seeds of Prunus tomentosa Thunberg.
    Archives of pharmacal research, 2008, Volume: 31, Issue:4

    Topics: Animals; Cell Survival; Chromones; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Glycosides; Indomethacin; Interferon-gamma; Kaempferols; Lipopolysaccharides; Macrophages; Mannosides; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Proanthocyanidins; Prunus; Quercetin; Seeds

2008
The anti-ulcerogenic effects of Curatella americana L.
    Journal of ethnopharmacology, 2009, Jan-30, Volume: 121, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Dilleniaceae; Dinoprostone; Ethylmaleimide; Gastric Mucosa; Gastrins; Hormones; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Bark; Plant Extracts; Proanthocyanidins; Somatostatin; Stomach Ulcer; Sulfhydryl Compounds

2009
Dietary grape seed proanthocyanidins inhibit 12-O-tetradecanoyl phorbol-13-acetate-caused skin tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin, which is associated with the inhibition of inflammatory responses.
    Carcinogenesis, 2009, Volume: 30, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Female; Grape Seed Extract; Inflammation; Mice; Papilloma; Plant Extracts; Proanthocyanidins; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate

2009
Effects of Areca catechu L. containing procyanidins on cyclooxygenase-2 expression in vitro and in vivo.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Areca; Blotting, Western; Carrageenan; Cell Line, Tumor; Chromans; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Male; Nuts; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2010
Dietary grape seed proanthocyanidins inhibit UVB-induced cyclooxygenase-2 expression and other inflammatory mediators in UVB-exposed skin and skin tumors of SKH-1 hairless mice.
    Pharmaceutical research, 2010, Volume: 27, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Proliferation; Chemoprevention; Cyclooxygenase 2; Cytokines; Diet; Dinoprostone; Female; Gene Expression Regulation, Neoplastic; Grape Seed Extract; Inflammation Mediators; Mice; Mice, Hairless; Proanthocyanidins; Skin; Skin Neoplasms; Ultraviolet Rays

2010
Proanthocyanidins inhibit in vitro and in vivo growth of human non-small cell lung cancer cells by inhibiting the prostaglandin E(2) and prostaglandin E(2) receptors.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Nude; Proanthocyanidins; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by phenolic compounds from roots of Rhododendron mucronulatum.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:9

    Topics: Anti-Inflammatory Agents; Antioxidants; Arabinose; Biflavonoids; Catechin; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Glucosides; Humans; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Plant Roots; Proanthocyanidins; Quercetin; Rhododendron

2011
Grape seed proanthocyanidins inhibit melanoma cell invasiveness by reduction of PGE2 synthesis and reversal of epithelial-to-mesenchymal transition.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Dinoprostone; Epithelial-Mesenchymal Transition; Grape Seed Extract; Humans; Immunoassay; Proanthocyanidins; Transfection

2011
Omega-3 docosahexaenoic acid and procyanidins inhibit cyclo-oxygenase activity and attenuate NF-κB activation through a p105/p50 regulatory mechanism in macrophage inflammation.
    The Biochemical journal, 2012, Jan-15, Volume: 441, Issue:2

    Topics: Biflavonoids; Catechin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Docosahexaenoic Acids; Fatty Acids, Omega-3; Humans; I-kappa B Proteins; Inflammation; Interleukin-6; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Proanthocyanidins; Transcription Factor RelA

2012
The procyanidin trimer C1 inhibits LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages.
    International immunopharmacology, 2013, Volume: 15, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Biflavonoids; Catechin; Cell Line; Cyclooxygenase 2; Dinoprostone; Inflammation; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; NF-kappa B; Nitric Oxide; Proanthocyanidins; Toll-Like Receptor 4

2013
Antagonizing effects and mechanisms of afzelin against UVB-induced cell damage.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Cell Line; Comet Assay; Cytoprotection; Dinoprostone; DNA Fragmentation; Humans; Interleukin-6; Keratinocytes; Lipid Peroxidation; Mannosides; Mice; NIH 3T3 Cells; Oxidative Stress; Proanthocyanidins; Pyrimidine Dimers; Radiation-Protective Agents; Tumor Necrosis Factor-alpha; Ultraviolet Rays

2013
Anti-inflammatory effect of procyanidins from wild grape (Vitis amurensis) seeds in LPS-induced RAW 264.7 cells.
    Oxidative medicine and cellular longevity, 2013, Volume: 2013

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Nucleus; Cell Survival; Cyclooxygenase 2; Dinoprostone; Grape Seed Extract; I-kappa B Proteins; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; Models, Biological; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Proanthocyanidins; Protein Transport; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Vitis

2013
Immunomodulatory effects of Hedysarum polybotrys extract in mice macrophages, splenocytes and leucopenia.
    Molecules (Basel, Switzerland), 2013, Dec-03, Volume: 18, Issue:12

    Topics: Animals; Astragalus Plant; Astragalus propinquus; Cell Line; Daunorubicin; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Immunologic Factors; Isoflavones; Leukopenia; Macrophages; Mice; Nitric Oxide; Plant Extracts; Proanthocyanidins; Quality Control; Spleen

2013
Prevention of oxidative stress, inflammation and mitochondrial dysfunction in the intestine by different cranberry phenolic fractions.
    Clinical science (London, England : 1979), 2015, Volume: 128, Issue:3

    Topics: Adenosine Triphosphate; Antioxidants; Apoptosis; Biflavonoids; Caco-2 Cells; Catechin; Dinoprostone; Fatty Acids; Humans; Inflammation; Intestines; Lipid Peroxidation; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Plant Extracts; Proanthocyanidins; Vaccinium macrocarpon

2015
Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption.
    Scientific reports, 2016, 09-19, Volume: 6

    Topics: Administration, Oral; Animals; Anterior Cruciate Ligament; Biflavonoids; Catechin; Cyclooxygenase 2; Diet; Dinoprostone; Disease Models, Animal; Female; Grape Seed Extract; Interleukin-1beta; Male; Mass Spectrometry; Matrix Metalloproteinase 13; Metabolome; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Olea; Osteoarthritis; Phenylethyl Alcohol; Proanthocyanidins; Rabbits; RNA, Messenger; Wounds and Injuries

2016
Procyanidin A2, a polyphenolic compound, exerts anti-inflammatory and anti-oxidative activity in lipopolysaccharide-stimulated RAW264.7 cells.
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cytokines; Dinoprostone; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Proanthocyanidins; RAW 264.7 Cells; Signal Transduction

2020
Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages.
    Inflammopharmacology, 2020, Volume: 28, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Cathepsin B; Cytokines; Dinoprostone; Gout; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophils; NLR Family, Pyrin Domain-Containing 3 Protein; Proanthocyanidins; Uric Acid

2020