Page last updated: 2024-08-16

procarbazine and hydrazine

procarbazine has been researched along with hydrazine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199021 (84.00)18.7374
1990's3 (12.00)18.2507
2000's1 (4.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kennedy, JH; McCue, JP1
Murphy, DL1
Braun, R; Wolf, G2
Braun, R; Mangold, R; Mangold, U1
Beisler, JA; Driscoll, JS; Peng, GW1
Erikson, JM; Prough, RA1
Erikson, JM; Prough, RA; Tweedie, DJ1
Herman, EH; Lee, I1
Deicher, H1
Bogdanov, NA1
Fishbein, L; Flamm, WG1
Prough, RA1
Brune, K; Floersheim, GL1
Eade, NR; MacLeod, SM; Renton, KW1
Oberhausen-Braun, H1
Chauhan, PS; Ehling, UH; Sotomayor, RE1
Gamberini, M; Leite, LC1
Armelin, MC; Cidade, MR; Gamberini, M; Leite, LC; Valotta, LA1
Akasaka, M; Ishibashi, S; Matsusaka, N; Saga, A; Sasaki, YF; Su, YQ; Tsuda, S; Yoshida, K1
BERUMEN, L; GUEVARA, GF1
TODD, ID1
RAAFLAUB, J; SCHWARTZ, DE1
BEGEMANN, H; BLUM, KU; DREWS, J; FELLMER, KE; FOELSCH, E; GERHARTZ, H; GRUNZE, H; HAUSMANN, K; HENNES, R; JUENGLING, W; KLEIBEL, F; KOERTGE, P; MARING, H; MARTIN, H; OBRECHT, P; OSTEN, W; PABST, HW; POLIWODA, H; SCHUBERT, JC; SEIDL, S; SPECHTER, HJ; STRICKSTROCK, KH; WITTE, S1
Gasowska-Bajger, B; Wojtasek, H1

Reviews

4 review(s) available for procarbazine and hydrazine

ArticleYear
The behavioral toxicity of monoamine oxidase-inhibiting antidepressants.
    Advances in pharmacology and chemotherapy, 1977, Volume: 14

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior; Behavior, Animal; Dextroamphetamine; Humans; Hydrazines; Iproniazid; Isocarboxazid; Levodopa; Lithium; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Procarbazine; Rats; Tranylcypromine; Tryptophan

1977
Metabolism of hydrazine anti-cancer agents.
    Pharmacology & therapeutics, 1987, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinogens; Humans; Hydrazines; Mutagens; Procarbazine

1987
[Poisoning by hydrazine derivatives (review of the literature)].
    Voenno-meditsinskii zhurnal, 1972, Volume: 11

    Topics: Animals; Antidotes; Carboxy-Lyases; Chemical Industry; DNA; Hydrazines; Iproniazid; Monoamine Oxidase Inhibitors; Nialamide; Occupational Medicine; Procarbazine; Pyridoxal Phosphate; Pyridoxine

1972
Potential environmental chemical hazards. I. Drugs.
    The Science of the total environment, 1972, Volume: 1, Issue:1

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Hexachlorophene; Humans; Hydrazines; Isoniazid; Phenacetin; Phenylbutazone; Phenytoin; Procarbazine; Salicylates

1972

Other Studies

21 other study(ies) available for procarbazine and hydrazine

ArticleYear
Oxidation of procarbazine in the presence of Ti(IV).
    Bioinorganic chemistry, 1977, Volume: 7, Issue:1

    Topics: Air; Catalysis; Chemical Phenomena; Chemistry; Copper; Free Radicals; Hydrazines; Hydrogen-Ion Concentration; Kinetics; Manganese; Oxidation-Reduction; Oxygen; Peroxides; Polarography; Procarbazine; Titanium

1977
[On the cytosic action of N-methyl-N-beta-chloraethyl-hydrazine and its benzaldehydhydrazone (author's transl)].
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Jun-15, Volume: 86, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Hydrazines; Hydrazones; Male; Mice; Procarbazine; Rats; Sarcoma, Yoshida

1976
[On the cytostatic mechanism of action of N-methyl-N-beta-chloroethylhydrazine and its benzaldehydhydrazone (author's transl)].
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Dec-09, Volume: 87, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Dimethylhydrazines; DNA, Neoplasm; Hydrazines; Hydrazones; Male; Mice; Neoplasm Proteins; Nucleotides; Procarbazine; RNA, Neoplasm

1976
The influence of N-methyl-N-beta-chloroethyl hydrazines on the mitotic index of Ehrlich ascites tumor cells and the leukopoiesis of the mouse.
    Experientia, 1977, Jan-15, Volume: 33, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Depression, Chemical; Hydrazines; Leukocyte Count; Leukocytes; Male; Mice; Mitosis; Mitotic Index; Procarbazine; Time Factors

1977
Potential antitumor agents: procarbazine analogs and other methylhydrazine derivatives.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:6

    Topics: Animals; Antineoplastic Agents; Hydrazines; Leukemia L1210; Mice; Monomethylhydrazine; Procarbazine; Structure-Activity Relationship

1977
Oxidative metabolism of some hydrazine derivatives by rat liver and lung tissue fractions.
    Journal of biochemical toxicology, 1986, Volume: 1, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Clorgyline; Cytochrome P-450 Enzyme System; Dimethylhydrazines; Hydrazines; Iproniazid; Liver; Lung; Male; Microsomes, Liver; Mitochondria, Liver; Monoamine Oxidase; Oxidation-Reduction; Pargyline; Procarbazine; Propylamines; Rats; Rats, Inbred Strains

1986
Cardiovascular and central nervous system effects of parenterally administered single doses of procarbazine (NSC-77,213).
    Toxicology and applied pharmacology, 1972, Volume: 22, Issue:3

    Topics: Anesthesia; Animals; Benzoates; Central Nervous System; Dogs; Drug Interactions; Electrodes, Implanted; Epinephrine; Haplorhini; Heart; Hemodynamics; Hydrazines; Infusions, Parenteral; Macaca; Male; Norepinephrine; Perfusion; Procarbazine; Propranolol; Reserpine; Time Factors; Tyramine; Venous Pressure

1972
[Immunosuppressive therapy in systemic lupus erythematosus].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:6

    Topics: Antibodies, Antinuclear; Autoantibodies; Azathioprine; Child; Collagen Diseases; Cyclophosphamide; Evaluation Studies as Topic; Humans; Hydrazines; Immunosuppression Therapy; Lupus Erythematosus, Systemic; Mercaptopurine; Prednisone; Procarbazine

1972
The N-oxidation of alkylhydrazines catalyzed by the microsomal mixed-function amine oxidase.
    Archives of biochemistry and biophysics, 1973, Volume: 158, Issue:1

    Topics: Aniline Compounds; Chromatography, Gas; Chromatography, Thin Layer; Hydrazines; Methanol; Microsomes, Liver; Monoamine Oxidase; Procarbazine; Spectrophotometry, Ultraviolet

1973
The haematological response to the immunosuppressive methylhydrazine derivates procarbazine and Ro 4-6824.
    Acta haematologica, 1971, Volume: 46, Issue:2

    Topics: Animals; Antilymphocyte Serum; Antineoplastic Agents; Benzoates; Blood Platelets; Body Weight; Erythrocytes; Female; Hydrazines; Immune Tolerance; Immunosuppression Therapy; Immunosuppressive Agents; Leukopenia; Lymphoid Tissue; Lymphopenia; Male; Mice; Mice, Inbred Strains; Neutrophils; Procarbazine; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous

1971
Inhibition of hepatic microsomal drug metabolism by the hydrazines Ro 4-4602, MK 486, and procarbazine hydrochloride.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:7

    Topics: Aminopyrine; Animals; Benzoates; Hydrazines; Male; Microsomes, Liver; Oxidoreductases; Procarbazine; Proteins; Rats; Rats, Inbred Strains; Sleep; Time Factors

1972
[Experimental findings in animals concerning radiation sensitization in partial and whole body irradiation].
    Strahlentherapie, 1972, Volume: 143, Issue:3

    Topics: Acetates; Animals; Antibiotics, Antineoplastic; Dogs; Fluorouracil; Glyoxylates; Hydrazines; Hydroquinones; Hydroxymercuribenzoates; Iron; Maleimides; Mice; Oxygen; Procarbazine; Radiation Effects; Radiation-Sensitizing Agents; Rats; Uridine; Vitamin K

1972
Induction of unscheduled DNA synthesis in the germ cells of male mice after treatment with hydrazine or procarbazine.
    Toxicology, 1982, Volume: 25, Issue:2-3

    Topics: Animals; DNA; Hydrazines; Male; Mice; Mice, Inbred C3H; Procarbazine; Spermatids; Spermatozoa; Thymidine

1982
Carbon-centered free radical formation during the metabolism of hydrazine derivatives by neutrophils.
    Biochemical pharmacology, 1993, May-05, Volume: 45, Issue:9

    Topics: 1,2-Dimethylhydrazine; Animals; Azides; Dimethylhydrazines; Female; Free Radicals; Hydrazines; L-Lactate Dehydrogenase; Monomethylhydrazine; Neutrophils; Nitrogen Oxides; Peritoneal Cavity; Peroxidase; Procarbazine; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

1993
Contribution of hydrazines-derived alkyl radicals to cytotoxicity and transformation induced in normal c-myc-overexpressing mouse fibroblasts.
    Carcinogenesis, 1998, Volume: 19, Issue:1

    Topics: 3T3 Cells; Animals; Cell Survival; Cell Transformation, Neoplastic; DNA Damage; DNA Replication; Electron Spin Resonance Spectroscopy; Exons; Female; Free Radicals; Genes, myc; Horseradish Peroxidase; Hydrazines; In Vitro Techniques; Mice; Monomethylhydrazine; Neutrophil Activation; Neutrophils; Procarbazine; Proto-Oncogene Proteins c-myc; Rats; Rats, Wistar; Recombinant Proteins; Thymidine; Transfection

1998
Organ-specific genotoxicity of the potent rodent colon carcinogen 1,2-dimethylhydrazine and three hydrazine derivatives: difference between intraperitoneal and oral administration.
    Mutation research, 1998, Jul-08, Volume: 415, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Carcinogens; Colon; Dimethylhydrazines; DNA Damage; Hydrazines; Injections, Intraperitoneal; Male; Mice; Mutagenicity Tests; Procarbazine

1998
[TRIAL THERAPY OF HODGKIN'S DISEASE AND OTHER LYMPHOMAS WITH METHLHYDRAZINE. P-(N'-METHYLHTDRAZINOMETHLY)-N-ISOPROPYL-BENZMIDE HCL (NATULAN)].
    Medicina, 1964, Nov-25, Volume: 44

    Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Humans; Hydrazines; Lymphoma; Procarbazine

1964
NATULAN IN MANAGEMENT OF LATE HODGKIN'S DISEASE, OTHER LYMPHORETICULAR NEOPLASMS, AND MALIGNANT MELANOMA.
    British medical journal, 1965, Mar-06, Volume: 1, Issue:5435

    Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Humans; Hydrazines; Lymphoma; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Melanoma; Mycosis Fungoides; Neoplasms; Palliative Care; Procarbazine; Toxicology

1965
[ON THE METABOLISM OF A CYTOSTATIC METHYLHYDRAZINE DERIVATIVE (NATULAN)].
    Experientia, 1965, Jan-15, Volume: 21

    Topics: Antineoplastic Agents; Blood; Body Fluids; Cytostatic Agents; Dogs; Hydrazines; Metabolism; Monomethylhydrazine; Procarbazine; Rats; Urine

1965
[RESULTS OF CLINICAL TESTS OF A NEW CYTOSTATIC SUBSTANCE FROM THE METHYLHYDRAZINE SERIES (NATULAN)].
    Medizinische Klinik, 1965, Jun-11, Volume: 60

    Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Humans; Hydrazines; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Methylhydrazines; Plasmacytoma; Procarbazine

1965
Indirect oxidation of the antitumor agent procarbazine by tyrosinase--possible application in designing anti-melanoma prodrugs.
    Bioorganic & medicinal chemistry letters, 2008, Jun-01, Volume: 18, Issue:11

    Topics: Agaricales; Antineoplastic Agents; Hydrazines; Melanoma; Molecular Structure; Monophenol Monooxygenase; Oxidation-Reduction; Oxygen Consumption; Procarbazine; Prodrugs; Structure-Activity Relationship

2008