Page last updated: 2024-09-03

procainamide 4-hydroxylamine and acecainide

procainamide 4-hydroxylamine has been researched along with acecainide in 4 studies

Compound Research Comparison

Studies
(procainamide 4-hydroxylamine)
Trials
(procainamide 4-hydroxylamine)
Recent Studies (post-2010)
(procainamide 4-hydroxylamine)
Studies
(acecainide)
Trials
(acecainide)
Recent Studies (post-2010) (acecainide)
12002861615

Protein Interaction Comparison

ProteinTaxonomyprocainamide 4-hydroxylamine (IC50)acecainide (IC50)
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)8.8
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)5

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, L; Heineman, WR; Hess, EV; Lunte, CE; Wheeler, JF1
Gill, EW; Jones, A; Sim, E; Stanley, L1
Adams, LE; Budinsky, R; Donovan-Brand, R; Hess, EV; Roberts, SM; Skoulis, NP; Zimmer, H1
Gleichmann, E; Goebel, C; Goebels, R; Kubicka-Muranyi, M; Uetrecht, J1

Other Studies

4 other study(ies) available for procainamide 4-hydroxylamine and acecainide

ArticleYear
Electrochemical determination of N-oxidized procainamide metabolites and functional assessment of effects on murine cells in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 188, Issue:3

    Topics: Acecainide; Animals; Ascorbic Acid; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; Cysteine; DNA; Electrochemistry; Electrolysis; Glutathione; Hydrogen-Ion Concentration; Kinetics; Mice; Oxidation-Reduction; Procainamide; Rats; Spectrophotometry; Spleen

1988
Metabolites of procainamide and practolol inhibit complement components C3 and C4.
    The Biochemical journal, 1988, Apr-15, Volume: 251, Issue:2

    Topics: Acecainide; Complement C3; Complement C4; Humans; Practolol; Procainamide; Protein Binding

1988
Procainamide hydroxylamine lymphocyte toxicity--I. Evidence for participation by hemoglobin.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:4

    Topics: Acecainide; Animals; Ascorbic Acid; Carbon Monoxide; Chemical Phenomena; Chemistry; Hemoglobins; In Vitro Techniques; Liver; Lymphocytes; Male; Methemoglobin; Monocytes; Procainamide; Rats; Rats, Inbred Strains; Spleen; Thymidine

1989
T lymphocytes ignore procainamide, but respond to its reactive metabolites in peritoneal cells: demonstration by the adoptive transfer popliteal lymph node assay.
    Toxicology and applied pharmacology, 1993, Volume: 122, Issue:1

    Topics: Acecainide; Acetylation; Animals; Female; Humans; Hydroxylation; Immunologic Memory; Lymph Nodes; Mice; Mice, Inbred A; Mice, Inbred C57BL; Peritoneal Cavity; Phagocytes; Procainamide; Spleen; T-Lymphocytes

1993