Page last updated: 2024-08-16

probenecid and zithromax

probenecid has been researched along with zithromax in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's8 (42.11)29.6817
2010's9 (47.37)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Johnson, RC; Luger, SW; Massarotti, EM; Messner, RP; Rahn, DW; Steere, AC; Wong, JB1
Chanteux, H; Michot, JM; Mingeot-Leclercq, MP; Seral, C; Tulkens, PM; Van Bambeke, F1
Hartmann, M1
Asakura, E; Baba, K; Hasegawa, T; Kitaichi, K; Nadai, M; Sugie, M; Takagi, K; Torita, S; Zhao, YL1
Michot, JM; Mingeot-Leclercq, MP; Tulkens, PM; Van Bambeke, F1
Lai, PC; Walters, JD1
Fisk, RE; Goire, N; Mak, DB; Speers, DJ1
Enriquez, RP; Lahra, MM1

Reviews

1 review(s) available for probenecid and zithromax

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for probenecid and zithromax

ArticleYear
Treatment of early Lyme disease.
    The American journal of medicine, 1992, Volume: 92, Issue:4

    Topics: Adult; Amoxicillin; Antibodies, Bacterial; Azithromycin; Borrelia burgdorferi Group; Doxycycline; Erythema Chronicum Migrans; Erythromycin; Female; Follow-Up Studies; Humans; Immunoglobulin G; Immunoglobulin M; Lyme Disease; Male; Middle Aged; Nervous System Diseases; Pilot Projects; Probenecid; Sensation; Treatment Outcome

1992

Other Studies

17 other study(ies) available for probenecid and zithromax

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3

    Topics: Acridines; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Cell Line; Cyclosporine; Cytosol; Gemfibrozil; Isoquinolines; Lysosomes; Macrophages; Mice; Microscopy, Confocal; Monensin; Probenecid; Tetrahydroisoquinolines; Verapamil

2003
[Therapy of syphilis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Controlled Clinical Trials as Topic; Doxycycline; Female; Follow-Up Studies; Humans; Male; Neurosyphilis; Penicillin G; Penicillin G Benzathine; Penicillin G Procaine; Penicillins; Practice Guidelines as Topic; Pregnancy; Probenecid; Prospective Studies; Syphilis; Syphilis Serodiagnosis; Time Factors; Uricosuric Agents

2004
Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:3

    Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Bile; Cyclosporine; Erythromycin; Hyperbilirubinemia; Immunosuppressive Agents; Intestinal Mucosa; Kidney; Liver; Male; Mitochondrial Proteins; Probenecid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renal Agents; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Tissue Distribution

2004
Active efflux of ciprofloxacin from J774 macrophages through an MRP-like transporter.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:7

    Topics: Adenosine Triphosphate; Anti-Infective Agents; Azithromycin; Blotting, Western; Carrier Proteins; Cell Line; Cell Survival; Ciprofloxacin; DNA; Drug Resistance; Drug Resistance, Multiple; Glutathione; Humans; Hydrogen-Ion Concentration; Ionophores; Macrophages; Microscopy, Confocal; Microscopy, Phase-Contrast; Monensin; Probenecid; Protons; Renal Agents; Sulfhydryl Compounds

2004
Azithromycin kills invasive Aggregatibacter actinomycetemcomitans in gingival epithelial cells.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Azithromycin; Biological Transport; Carnitine; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Gingiva; Humans; Kinetics; Probenecid; Procainamide; Pyrilamine; Quinidine; Time Factors

2013
Non-culture Neisseria gonorrhoeae molecular penicillinase production surveillance demonstrates the long-term success of empirical dual therapy and informs gonorrhoea management guidelines in a highly endemic setting.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:5

    Topics: Administration, Oral; Amoxicillin; Azithromycin; Drug Therapy, Combination; Epidemiological Monitoring; Gonorrhea; Humans; Neisseria gonorrhoeae; Penicillinase; Plasmids; Probenecid; Western Australia

2014
Australian Gonococcal Surveillance Programme, 1 July to 30 September 2015.
    Communicable diseases intelligence quarterly report, 2016, Mar-31, Volume: 40, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Australia; Azithromycin; Ceftriaxone; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillins; Probenecid; Public Health Surveillance

2016