Page last updated: 2024-08-16

probenecid and warfarin

probenecid has been researched along with warfarin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19907 (23.33)18.7374
1990's3 (10.00)18.2507
2000's9 (30.00)29.6817
2010's11 (36.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Berger, W1
Stein, GE1
Drieman, JC; Thijssen, HH1
McNamara, PJ; Stoeckel, K; Trueb, V1
Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K1
Nies, AS1
Holmes, J; Sapeika, N; Zwarenstein, H1
Gröbner, W; Zöllner, N1
Kaul, S; Ritschel, WA1
Cacini, W; Ritschel, WA1
Balchen, M; Gjelstad, A; Pedersen-Bjergaard, S; Rasmussen, KE1
Fawcett, JP; Gu, J; Li, P; Tang, Y; Wang, Y1
Cao, YC; Liang, XL; Liao, ZG; Yang, M; Zhao, GW; Zhao, LJ; Zhu, ML1

Reviews

3 review(s) available for probenecid and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug interactions with fluoroquinolones.
    The American journal of medicine, 1991, Dec-30, Volume: 91, Issue:6A

    Topics: 4-Quinolones; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Cyclosporine; Drug Interactions; Humans; Metals; Probenecid; Warfarin; Xanthines

1991
Drug interactions.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Anabolic Agents; Antidepressive Agents; Biological Transport, Active; Cholestyramine Resin; Clofibrate; Drug Interactions; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kaolin; Kidney; Pharmaceutical Preparations; Phenylbutazone; Probenecid; Protein Binding; Thyroxine; Warfarin

1974

Other Studies

27 other study(ies) available for probenecid and warfarin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
[Interactions between oral antidiabetics and other drugs].
    Therapeutische Umschau. Revue therapeutique, 1976, Volume: 33, Issue:9

    Topics: Chloramphenicol; Coumarins; Drug Interactions; Humans; Hypoglycemic Agents; Probenecid; Sulfonamides

1976
Renal selective N-acetyl-L-gamma-glutamyl prodrugs. III. N-acetyl-L-gamma-glutamyl-4'-aminowarfarin is not targeted to the kidney but is selectively excreted into the bile.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: Animals; Bile; Buthionine Sulfoximine; Indocyanine Green; Kidney; Liver; Male; Methionine Sulfoximine; Organ Specificity; Probenecid; Prodrugs; Protein Binding; Rats; Rats, Inbred Strains; Tissue Distribution; Vitamin K; Warfarin

1991
Ceftriaxone binding to human serum albumin. Indirect displacement by probenecid and diazepam.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Binding Sites; Blood Proteins; Ceftriaxone; Chromatography, High Pressure Liquid; Diazepam; Drug Interactions; Fatty Acids, Nonesterified; Humans; Phenytoin; Probenecid; Serum Albumin; Warfarin

1990
Distribution of chlorpromazine in a simplified blood influenced by various drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 278, Issue:1

    Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental

1973
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts

1973
[Uricosuric agents].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:10

    Topics: Adult; Benzofurans; Coumarins; Humans; Indenes; Kidney Function Tests; Middle Aged; Probenecid; Uric Acid; Uricosuric Agents; Zoxazolamine

1971
Studies of the intestinal transfer of coumarin and 7-hydroxycoumarin across guinea pig and rat small intestine.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:5

    Topics: Animals; Coumarins; Guinea Pigs; Intestinal Absorption; Potassium Cyanide; Probenecid; Rats; Umbelliferones

1981
The excretion of coumarin and hydroxycoumarins by the avian kidney in vivo.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 243, Issue:2

    Topics: 4-Hydroxycoumarins; Animals; Chickens; Coumarins; Infusions, Parenteral; Kidney; Portal Vein; Probenecid; Umbelliferones

1980
Electrokinetic migration of acidic drugs across a supported liquid membrane.
    Journal of chromatography. A, 2007, Jun-08, Volume: 1152, Issue:1-2

    Topics: Acids; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Gemfibrozil; Heptanol; Hydrogen-Ion Concentration; Ketoprofen; Membranes, Artificial; Naproxen; Pharmaceutical Preparations; Probenecid; Reproducibility of Results; Warfarin

2007
Quantitation of Armillarisin A in human plasma by liquid chromatography-electrospray tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: Administration, Oral; Benzopyrans; Calibration; Chromatography, Liquid; Coumarins; Ether; Humans; Methylene Chloride; Molecular Structure; Probenecid; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Time Factors

2007
[Study on transport mechanism of baicalin in Scutellariae radix extracts and effect of Angelica dahurica extracts on transport of baicalin by Caco-2 cell monolayer model].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:14

    Topics: Angelica; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Coumarins; Drug Interactions; Drugs, Chinese Herbal; Flavonoids; Humans; Intestinal Absorption; Oils, Volatile; Plant Extracts; Plant Roots; Probenecid; Scutellaria baicalensis; Verapamil

2013