Page last updated: 2024-08-16

probenecid and taurocholic acid

probenecid has been researched along with taurocholic acid in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.00)18.7374
1990's4 (16.00)18.2507
2000's12 (48.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foguet, M; Hagenbuch, B; Lübbert, H; Meier, PJ; Stieger, B1
Hagenbuch, B; Kullak-Ublick, GA; Meier, PJ; Stieger, B; Wolkoff, AW1
Hashimoto, Y; Ibaramoto, K; Inui, KI; Masuda, S; Saito, H; Takeuchi, A1
Cha, SH; Endou, H; Kanai, Y; Kojima, R; Kusuhara, H; Sekine, T; Sugiyama, Y; Tsuda, M; Utsunomiya-Tate, N1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T1
Abe, T; Endou, H; Kusuhara, H; Meier, PJ; Sekine, T; Shitara, Y; Sugiyama, D; Sugiyama, Y; Suzuki, H1
Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H1
Hummel-Eisenbeiss, J; Jedlitschky, G; Keppler, D; Nies, AT; Rius, M1
Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T1
Kusuhara, H; Sugiyama, Y; Tohyama, K1
Belinsky, MG; Chen, ZS; Guo, Y; Kotova, E; Kruh, GD1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Damm, KH; Erttmann, RR1
Nakashima, E; Takanosu, K; Tamai, I; Terasaki, T; Tsuji, A1
Billing, BH; Chitranukroh, A; Taggart, G1
Burckhardt, G; Murer, H; Rumrich, G; Ullrich, KJ; Wilson, FA1
Beier, DR; Fujiwara, Y; Miller, DS; Nigam, SK; Pritchard, JB; Sweet, DH1
Chan, LM; Miller, DS; Pritchard, JB; Sweet, DH; Walden, R; Yang, XP1
Fehsenfeld, H; Greven, J; Schlattjan, JH1
Badolo, L; Jørgensen, L; Lund, S; Schousboe, A; Van Beek, J1
Adachi, Y; Fujishima, M; Kusuhara, H; Miyajima, M; Sugiyama, Y1

Reviews

1 review(s) available for probenecid and taurocholic acid

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Other Studies

24 other study(ies) available for probenecid and taurocholic acid

ArticleYear
Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Dec-01, Volume: 88, Issue:23

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Carrier Proteins; Cloning, Molecular; DNA; Female; Gene Library; Liver; Molecular Sequence Data; Molecular Weight; Oocytes; Organic Anion Transporters, Sodium-Dependent; Protein Conformation; Rats; Restriction Mapping; RNA, Messenger; Sodium; Symporters; Taurocholic Acid; Xenopus laevis

1991
Functional characterization of the basolateral rat liver organic anion transporting polypeptide.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:2

    Topics: Animals; Anion Transport Proteins; Bile Acids and Salts; Carrier Proteins; Female; In Vitro Techniques; Indocyanine Green; Ion Transport; Liver; Oocytes; Rats; Sulfobromophthalein; Xenopus laevis

1994
Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney.
    Molecular pharmacology, 1999, Volume: 55, Issue:4

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Kidney; Male; Membrane Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Oocytes; Organic Anion Transporters; Rats; Rats, Wistar; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Tissue Distribution; Transfection; Xenopus laevis

1999
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.
    The Journal of biological chemistry, 1999, May-07, Volume: 274, Issue:19

    Topics: Amino Acid Sequence; Animals; Brain; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Estrone; Molecular Sequence Data; Ochratoxins; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis

1999
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis

2001
Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Animals; Anion Transport Proteins; Blood-Brain Barrier; Brain; Carrier Proteins; Digoxin; Enzyme Inhibitors; Estradiol; Glucuronates; Male; Microinjections; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Probenecid; Rats; Rats, Wistar; Taurocholic Acid

2001
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.
    Cancer research, 2001, Oct-01, Volume: 61, Issue:19

    Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium

2001
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
    Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Polarity; Cholagogues and Choleretics; Cricetinae; Fibroblasts; Gene Expression; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Rats; Taurocholic Acid; Transfection; Transport Vesicles; Tritium

2003
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger

2004
Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier.
    Endocrinology, 2004, Volume: 145, Issue:9

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Cerebellum; Cerebral Cortex; Choroid Plexus; Estradiol; Iodine Radioisotopes; Male; Mice; Organic Cation Transport Proteins; Thyroxine; Triiodothyronine

2004
Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).
    Molecular pharmacology, 2005, Volume: 67, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Dose-Response Relationship, Drug; Estradiol; Humans; Leukotriene C4; LLC-PK1 Cells; Protein Transport; Swine

2005
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
On the problem of a common hepatic transport process for steroids. Uptake of 3-H-taurocholic acid and 3-H-corticosterone into rat liver slices.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:2

    Topics: Aminohippuric Acids; Animals; Binding, Competitive; Biological Transport; Corticosterone; In Vitro Techniques; Liver; Ouabain; Oxygen Consumption; Probenecid; Rats; Taurocholic Acid; Tritium

1975
Kinetic evidence for a common transport route of benzylpenicillin and probenecid by freshly prepared hepatocytes in rats. Influence of sodium ion, organic anions, amino acids and peptides on benzylpenicillin uptake.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:1

    Topics: Amino Acids; Animals; Anions; Cattle; Cephalosporins; In Vitro Techniques; Kinetics; Liver; Male; p-Aminohippuric Acid; Penicillin G; Peptides; Probenecid; Rats; Rats, Inbred Strains; Serum Albumin; Serum Albumin, Bovine; Sodium; Taurocholic Acid

1986
Enhancement of the urinary excretion of non-sulphated and sulphated radioactive bile acids by sodium acetate in the bile duct obstructed rat.
    Clinical science (London, England : 1979), 1985, Volume: 68, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Bile Acids and Salts; Cholestasis; Glomerular Filtration Rate; Glycochenodeoxycholic Acid; Glycocholic Acid; Kidney Function Tests; Male; Probenecid; Protein Binding; Rats; Rats, Inbred Strains; Stimulation, Chemical; Taurocholic Acid; Urodynamics

1985
Sodium-coupled taurocholate transport in the proximal convolution of the rat kidney in vivo and in vitro.
    The Journal of clinical investigation, 1981, Volume: 67, Issue:4

    Topics: Animals; Bile Acids and Salts; Biological Transport, Active; Cations; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Male; Membrane Potentials; Microvilli; Probenecid; Rats; Sodium; Taurocholic Acid

1981
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.
    The Journal of biological chemistry, 2002, Jul-26, Volume: 277, Issue:30

    Topics: Animals; Anions; Biological Transport; Blotting, Northern; Brain; Cerebrospinal Fluid; Choroid Plexus; Cloning, Molecular; Estrone; Kidney; Liver; Mice; Mice, Knockout; Microscopy, Confocal; Models, Genetic; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Phenotype; Probenecid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfobromophthalein; Taurocholic Acid; Xenopus

2002
Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:4

    Topics: Animals; Dicarboxylic Acids; Estrone; Glutarates; In Vitro Techniques; Ion Transport; Lithium; Microinjections; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Probenecid; Rats; Sodium; Taurocholic Acid; Xenopus laevis

2003
Effect of the dimeric bile acid analogue S 0960, a specific inhibitor of the apical sodium-dependent bile salt transporter in the ileum, on the renal handling of taurocholate.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:12

    Topics: Animals; Bile Acids and Salts; Bile Ducts; Carrier Proteins; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Ileum; In Vitro Techniques; Kidney; Kidney Tubules, Proximal; Lithium Chloride; Male; Microvilli; Organic Anion Transporters, Sodium-Dependent; Probenecid; Protein Binding; Rats; Rats, Sprague-Dawley; Renal Agents; Symporters; Taurocholic Acid

2003
Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 30, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Cells, Cultured; Cryopreservation; Female; Hepatocytes; Immunohistochemistry; Ketoconazole; Male; Organic Anion Transport Protein 1; Probenecid; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taurocholic Acid; Time Factors; Vinblastine

2007
Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

    Topics: Animals; Anions; Biological Transport; Blood-Brain Barrier; Brain; Dehydroepiandrosterone Sulfate; Estrone; Female; HEK293 Cells; Humans; Male; Mice; Mice, Knockout; Microinjections; Oocytes; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Probenecid; RNA, Complementary; Taurocholic Acid; Xenopus laevis

2011