Page last updated: 2024-08-16

probenecid and sulfamethoxazole

probenecid has been researched along with sulfamethoxazole in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199015 (60.00)18.7374
1990's0 (0.00)18.2507
2000's5 (20.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ruskin, J; Sattler, FR1
Bresher, JT; Duncan, WC; Eakins, W; Knox, JM; Nelson, M1
Duncan, WC; Jackson, TH; Knox, JM1
From, E; Kristensen, JK1
Brasch, H; Iven, H1
Caranasos, GJ; Cluff, LE; Stewart, RB1
Christensen, ML; Evans, WE1
Freyens, P; Meheus, AZ; Ngamije, E1
Rodin, P; Seth, AD1
Austin, TW; Bethel, M; Brooks, GF; Holmes, KK; Roberts, FL; Turck, M1
Nicol, CS2
Guinan, ME; Holmes, KK; Johnson, C; McCormack, WM; Stamm, WE; Starcher, T1
Bjerk, O; Csángó, PA; Gundersen, T; Jagars, G; Salveson, A1
Williams, RA1

Reviews

2 review(s) available for probenecid and sulfamethoxazole

ArticleYear
Clinically desirable drug interactions.
    Annual review of pharmacology and toxicology, 1985, Volume: 25

    Topics: Aminoglycosides; Amoxicillin; Ampicillin; Antacids; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Carbidopa; Diuretics; Drug Combinations; Drug Interactions; Drug Synergism; Humans; Hydroxamic Acids; Hypokalemia; Levodopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease; Penicillins; Probenecid; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Drug interactions with methotrexate.
    The Journal of rheumatology. Supplement, 1985, Volume: 12 Suppl 12

    Topics: Absorption; Anti-Bacterial Agents; Arthritis, Rheumatoid; Aspirin; Biological Transport; Cell Membrane; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Folic Acid; Humans; Kidney Tubules; Methotrexate; Probenecid; Protein Binding; Salicylates; Serum Albumin; Sulfamethoxazole; Sulfonamides; Tissue Distribution

1985

Trials

5 trial(s) available for probenecid and sulfamethoxazole

ArticleYear
Therapy of gonorrhea. Comparison of trimethoprim-sulfamethoxazole and ampicillin.
    JAMA, 1978, Nov-17, Volume: 240, Issue:21

    Topics: Ampicillin; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin Resistance; Penicillinase; Probenecid; Sulfamethoxazole; Trimethoprim

1978
Comparison of trimethoprim-sulfamethoxazole with penicillin and tetracycline in the treatment of uncomplicated gonorrhea in women.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Follow-Up Studies; Gonorrhea; Humans; Injections, Intramuscular; Middle Aged; Neisseria gonorrhoeae; Penicillin G Procaine; Probenecid; Sulfamethoxazole; Tetracycline; Trimethoprim

1975
Gonorrhea. Trimethoprim-sulfamethoxazole in the treatment of gonococcal urethritis: clinical and laboratory correlates.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Drug Combinations; Follow-Up Studies; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Penicillin G Procaine; Probenecid; Sulfamethoxazole; Tetracycline; Trimethoprim; United States; Urethritis

1973
Effect of treatment regimens for Neisseria gonorrhoeae on simultaneous infection with Chlamydia trachomatis.
    The New England journal of medicine, 1984, Mar-01, Volume: 310, Issue:9

    Topics: Adolescent; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Female; Gonorrhea; Humans; Lymphogranuloma Venereum; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Probenecid; Random Allocation; Sex Factors; Sulfamethoxazole; Tetracycline; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urethritis; Uterine Cervicitis

1984
Treatment of acute gonococcal urethritis in men with simultaneous infection with Chlamydia trachomatis.
    The British journal of venereal diseases, 1984, Volume: 60, Issue:2

    Topics: Acute Disease; Ampicillin; Anti-Infective Agents, Urinary; Chlamydia Infections; Chlamydia trachomatis; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Gonorrhea; Humans; Male; Probenecid; Random Allocation; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urethritis

1984

Other Studies

18 other study(ies) available for probenecid and sulfamethoxazole

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Trimethoprim-sulfamethoxazole in the treatment of gonorrhea: comparison with standard treatment schedules.
    Southern medical journal, 1975, Volume: 68, Issue:9

    Topics: Ampicillin; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin G Procaine; Probenecid; Sulfamethoxazole; Tetracycline; Trimethoprim

1975
Trimethoprim-sulphamethoxazole in gonorrhoea. A comparison with privampicillin combined with probenecid.
    The British journal of venereal diseases, 1975, Volume: 51, Issue:1

    Topics: Ampicillin; Drug Combinations; Dyspepsia; Erythema; Female; Gonorrhea; Humans; Male; Palatine Tonsil; Pivampicillin; Probenecid; Sulfamethoxazole; Trimethoprim

1975
The effects of antibiotics and uricosuric drugs on the renal elimination of methotrexate and 7-hydroxymethotrexate in rabbits.
    Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Benzbromarone; Ceftriaxone; Furosemide; Kidney; Metabolic Clearance Rate; Methotrexate; Piperacillin; Probenecid; Rabbits; Sulfamethoxazole; Sulfinpyrazone; Uricosuric Agents

1988
Treatment of gonorrhoea with trimethoprim-sulphamethoxazole and probenecid plus procaine penicillin in Rwanda.
    The British journal of venereal diseases, 1974, Volume: 50, Issue:6

    Topics: Drug Combinations; Female; Gonorrhea; Humans; Injections, Intramuscular; Male; Penicillin G Procaine; Probenecid; Rwanda; Sulfamethoxazole; Trimethoprim

1974
Treatment of gonorrhoea with cotrimoxazole, procaine penicillin alone, and procaine penicillin plus probenecid.
    The British journal of venereal diseases, 1972, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Drug Combinations; Folic Acid Antagonists; Follow-Up Studies; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neisseria gonorrhoeae; Penicillin G Procaine; Penicillins; Probenecid; Pyrimidines; Recurrence; Sulfamethoxazole; Sulfonamides; Trimethoprim; Urethritis

1972
Venereal disease in women. II.
    British medical journal, 1971, May-15, Volume: 2, Issue:5758

    Topics: Chancroid; Culture Media; Cytodiagnosis; Female; Folic Acid Antagonists; Gonorrhea; Humans; Kanamycin; Neisseria gonorrhoeae; Penicillin G; Physical Examination; Probenecid; Pyrimidines; Sulfamethoxazole; Vaginal Smears

1971
[Gonorrhea in women].
    Gynakologische Rundschau, 1970, Volume: 10, Issue:3

    Topics: Ampicillin; Culture Media; Female; Gonorrhea; Humans; Kanamycin; Probenecid; Sulfamethoxazole; Trimethoprim; Vaginal Smears

1970
Penicillinase-producing Neisseria gonorrhoeae.
    American family physician, 1981, Volume: 24, Issue:6

    Topics: beta-Lactamases; Communicable Disease Control; Female; Gonorrhea; Humans; Injections, Intramuscular; Male; Neisseria gonorrhoeae; Penicillin G Procaine; Penicillin Resistance; Penicillinase; Philippines; Probenecid; Spectinomycin; Sulfamethoxazole; Trimethoprim; United States

1981