probenecid has been researched along with pyrimethamine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Masseno, V; Muriithi, S; Nzila, A | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Renschler, HE; Schumacher, K | 1 |
| Adedeji, AA; Falade, CO; Fateye, BA; Fehintola, FA; Gbotosho, GO; Happi, TC; Oduola, AM; Sowunmi, A; Tambo, E | 1 |
| Adedeji, AA; Fateye, BA; Fehintola, FA; Sowunmi, A | 1 |
| Kokwaro, G; Marsh, K; Nzila, AM; Ward, SA; Winstanley, PA | 1 |
| Basco, LK; Tahar, R | 1 |
| Gutman, J; Kachur, SP; Mutabingwa, T; Nzila, A; Slutsker, L | 1 |
3 review(s) available for probenecid and pyrimethamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Therapeutic potential of folate uptake inhibition in Plasmodium falciparum.
Topics: Animals; Antimalarials; Drug Combinations; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Folic Acid; Folic Acid Antagonists; Malaria, Falciparum; Plasmodium falciparum; Probenecid; Pyrimethamine; Sulfadoxine | 2004 |
Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy.
Topics: Antimalarials; Chemoprevention; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2012 |
1 trial(s) available for probenecid and pyrimethamine
| Article | Year |
|---|---|
Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children.
Topics: Acute Disease; Antimalarials; Child; Child, Preschool; Drug Combinations; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Parasitemia; Probenecid; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2004 |
11 other study(ies) available for probenecid and pyrimethamine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
[Streptococcus angina, myocarditis and toxoplasmosis following splenectomy].
Topics: Accidents, Traffic; Administration, Oral; Adult; Antistreptolysin; Biopsy; Complement Fixation Tests; Diagnosis, Differential; Electrocardiography; Female; Humans; Injections, Intravenous; Lymphadenitis; Myocarditis; Penicillins; Probenecid; Pyrimethamine; Serologic Tests; Spleen; Splenectomy; Streptococcal Infections; Sulfadiazine; Tonsillectomy; Tonsillitis; Toxoplasma; Toxoplasmosis | 1970 |
Comparative effects of pyrimethamine-sulfadoxine, with and without probenecid, on Plasmodium falciparum gametocytes in children with acute, uncomplicated malaria.
Topics: Acute Disease; Animals; Antimalarials; Child; Drug Combinations; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Probenecid; Pyrimethamine; Sex Ratio; Sulfadoxine; Treatment Outcome; Uricosuric Agents | 2004 |
Molecular epidemiology of malaria in Cameroon. XXVI. Twelve-year in vitro and molecular surveillance of pyrimethamine resistance and experimental studies to modulate pyrimethamine resistance.
Topics: Adolescent; Animals; Antimalarials; Cameroon; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Molecular Epidemiology; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Probenecid; Pyrimethamine; Sequence Analysis, DNA; Sulfinpyrazone; Tetrahydrofolate Dehydrogenase | 2007 |