Page last updated: 2024-08-16

probenecid and physostigmine

probenecid has been researched along with physostigmine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's1 (7.14)18.2507
2000's1 (7.14)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Davis, KL; Goodwin, FK; Gordon, EK; Hollister, LE1
Korf, J; Westerink, BH1
Van Woert, MH; Weintraub, MI1
Aquilonius, SM; Sjöström, R1
Barchas, JD; Berger, PA; Davis, KL; Faull, KF; Hollister, LE1
Iley, J; Mendes, E; Moreira, R; Souza, S1

Reviews

1 review(s) available for probenecid and physostigmine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for probenecid and physostigmine

ArticleYear
Neurotransmitter metabolites in the cerebrospinal fluid of man following physostigmine.
    Life sciences, 1977, Oct-01, Volume: 21, Issue:7

    Topics: Adult; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neurotransmitter Agents; Physostigmine; Probenecid; Scopolamine

1977
Alterations in cerebrospinal fluid dopamine metabolites following physostigmine infusion.
    Psychopharmacology, 1981, Volume: 72, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Homovanillic Acid; Humans; Male; Middle Aged; Physostigmine; Probenecid

1981

Other Studies

11 other study(ies) available for probenecid and physostigmine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Aminooxyacetic Acid; Animals; Atropine; Brain; Brain Chemistry; Clozapine; Corpus Striatum; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Male; Morphine; Oxotremorine; Phenylacetates; Physostigmine; Pimozide; Probenecid; Rats; Substantia Nigra; Trihexyphenidyl

1975
Predicting the response to levodopa.
    Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707

    Topics: Calcinosis; Capillaries; Central Nervous System; Cerebrospinal Fluid; Cerebrovascular Disorders; Dihydroxyphenylalanine; Humans; Hypercalcemia; Injections, Intravenous; Male; Middle Aged; Parathyroid Diseases; Parkinson Disease; Phenylacetates; Physostigmine; Probenecid; Prognosis

1971
Cholinergic and dopaminergic mechanisms in Huntington's chorea.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Apr-01, Volume: 10, Issue:7

    Topics: Acetylcholine; Adult; Blood Pressure; Dopamine; Female; Heart Rate; Humans; Huntington Disease; Male; Middle Aged; Motor Activity; Movement; Neostigmine; Phenylacetates; Physostigmine; Probenecid; Synaptic Transmission; Tropanes

1971
Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 9, Issue:2

    Topics: Amides; Animals; Benzoic Acid; Carboxylic Acids; Clofibric Acid; Diclofenac; Drug Interactions; Esters; Hydrolases; Hydrolysis; Ibuprofen; In Vitro Techniques; Liver; Male; Naproxen; Physostigmine; Proadifen; Probenecid; Prodrugs; Rats; Rats, Sprague-Dawley; Refractometry; Solubility; Structure-Activity Relationship; Time Factors; Valproic Acid

1999