Page last updated: 2024-08-16

probenecid and organophosphonates

probenecid has been researched along with organophosphonates in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.03)18.7374
1990's15 (45.45)18.2507
2000's12 (36.36)29.6817
2010's5 (15.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonjour, JP; Fleisch, H; Troehler, U1
Cundy, KC; Fisher, PE; Flaherty, J; Hitchcock, MJ; Jaffe, HS; Lalezari, JP; Lietman, PS; Petty, BG; Polis, MA; Wachsman, M1
Cundy, K; Drew, WL; Fisher, PE; Flaherty, J; Glutzer, E; Hannigan, J; James, C; Lalezari, JP; Martin, JC; Miner, D1
Arevalo, JF; Chavez de la Paz, E; de Clercq, E; Freeman, WR; Kirsch, LS; Munguia, D1
Castanheira, I; Neves, M; Patricio, L; Paulo, A; Sawas-Dimopoulou, C1
Dorrestein, GM; Franssen, FF; Hermsen, RC; Nieuwenhuijs, H; Overdulve, JP; Smeijsters, LJ1
Cundy, KC; Hitchcock, MJ; Lee, WA; Li, ZH1
Cundy, KC; Lee, WA; Li, ZH1
Lalezari, JP1
Arevalo, JF; Chavez-de la Paz, E; De Clercq, E; Freeman, WR; Kirsch, LS; Munguia, D; Rahhal, FM1
Hardy, WD; Holland, GN; Ives, DV; Jaffe, HS; Johnson, M; Kemper, CA; Kramer, F; Kuppermann, BD; Lalezari, JP; Lewis, RA; McKinley, GF; Nelson, R; Northfelt, DW; Ruby, AE; Simon, GL; Stagg, RJ; Weinberg, DV; Wolitz, RA; Youle, M1
Engler, RJ; Katial, RK; Myers, KW1
Cundy, KC; Hitchcock, MJ; Lacy, SA; Lee, WA; Tellier, P1
Cundy, KC1
Cihlar, T; Ho, ES; Lin, DC; Mendel, DB1
Pavesio, C; Scott, RA1
Bowers, M1
Miller, DS1
Chakrabarti, S; Collingham, KE; Fegan, CD; Milligan, DW; Osman, H1
Duncan, BA; Ingrosso, A; Mucci, M; Nickens, DJ; Rodríguez, CA; Wolf, DL1
Bodart, E; de Bilderling, G; De Clercq, E; Lawson, G; Naesens, L; Remacle, M; Snoeck, R; Tuerlinckx, D1
Araya, CE; Dharnidharka, VR; Fennell, RS; Lew, JF; Neiberger, RE1
Aymard, G; Deray, G; Isnard Bagnis, C; Jaudon, MC; Lechat, P; Servais, A; Urien, S; Zahr, N2
Ida, H; Inui, K; Katsura, T; Tsuji, Y; Uwai, Y1
Barrios, C; Mir, ML; Puig, JM1
Castagnola, E; Cirillo, C; Cuzzubbo, D; Dallorso, S; Di Marco, E; Faraci, M; Lanino, E; Moroni, C; Morreale, G1
Benhamou, Y; Izzedine, H; Peytavin, G; Schneider, L; Thibault, V; Valantin, MA1
Czock, D; Keller, F1
Gao, Y; Momper, JD; Randhawa, PS; Schonder, KS; Shapiro, R; Venkataramanan, R; Zhao, Y1
Gattringer, KB; Jäger, W; Kraff, S; Thalhammer, F; Vossen, MG1
Fujita, T; Horita, S; Ikeda, Y; Kondo, T; Kumagai, Y; Kusuhara, H; Maeda, K; Nakayama, H; Sugiyama, Y; Tanabe, K; Tian, Y1

Reviews

2 review(s) available for probenecid and organophosphonates

ArticleYear
Cidofovir: a new therapy for cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytomegalovirus Retinitis; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kidney; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Agents

1997
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir.
    Clinical pharmacokinetics, 1999, Volume: 36, Issue:2

    Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Interactions; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Insufficiency

1999

Trials

7 trial(s) available for probenecid and organophosphonates

ArticleYear
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue.
    The Journal of infectious diseases, 1995, Volume: 171, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatine; Cytomegalovirus Infections; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Proteinuria; Semen; Virus Shedding

1995
Intravitreal cidofovir (HPMPC) treatment of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1995, Volume: 102, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; Humans; Injections; Intraocular Pressure; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Retina; Uveitis; Vitreous Body

1995
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical
    Annals of internal medicine, 1997, Feb-15, Volume: 126, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Drug Administration Schedule; Female; Fluid Therapy; Humans; Kidney Diseases; Male; Organophosphonates; Organophosphorus Compounds; Probenecid; Prospective Studies; Renal Agents; Visual Acuity

1997
Anterior nongranulomatous uveitis after intravitreal HPMPC (cidofovir) for the treatment of cytomegalovirus retinitis. Analysis and prevention.
    Ophthalmology, 1997, Volume: 104, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Glucocorticoids; Granuloma; Humans; Incidence; Injections; Iritis; Mydriatics; Organophosphonates; Organophosphorus Compounds; Probenecid; Prospective Studies; Uricosuric Agents; Vitreous Body

1997
Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Apr-01, Volume: 17, Issue:4

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatinine; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intraocular Pressure; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Proteinuria; Recurrence; Renal Agents; Risk Factors; Visual Acuity

1998
Pharmacokinetics and renal effects of cidofovir with a reduced dose of probenecid in HIV-infected patients with cytomegalovirus retinitis.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Kidney; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid

2003
Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Aug-01, Volume: 59

    Topics: Adenine; Adult; Drug Interactions; HEK293 Cells; Humans; In Vitro Techniques; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; p-Aminohippuric Acid; Penicillin G; Probenecid; Young Adult

2014

Other Studies

24 other study(ies) available for probenecid and organophosphonates

ArticleYear
Renal secretion of diphosphonates in rats.
    Kidney international, 1975, Volume: 8, Issue:1

    Topics: Aminohippuric Acids; Animals; Bicarbonates; Edetic Acid; Glomerular Filtration Rate; Hydrochloric Acid; Hydrogen-Ion Concentration; Inulin; Kidney; Male; Niacinamide; Organophosphonates; Phosphates; Probenecid; Rats; Urine

1975
Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Immunocompromised Host; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid

1995
Preparation and biological characteristics of 99mTc-diol a renal agent.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:3

    Topics: Acid-Base Imbalance; Animals; Autoradiography; Blood Proteins; Chemical Phenomena; Chemistry, Physical; Female; Fosfomycin; Hydrolysis; Kidney; Magnetic Resonance Spectroscopy; Male; Mice; Organophosphonates; Organotechnetium Compounds; Probenecid; Protein Binding; Radionuclide Imaging; Rats; Reagent Kits, Diagnostic; Tissue Distribution; Uric Acid

1993
Antimalarial and toxic effects of the acyclic nucleoside phosphonate (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine in Plasmodium berghei-infected mice.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7

    Topics: Adenine; Animals; Antimalarials; Delayed-Action Preparations; Malaria; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Plasmodium berghei; Probenecid

1996
Pharmacokinetics of cidofovir in monkeys. Evidence for a prolonged elimination phase representing phosphorylated drug.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Chlorocebus aethiops; Cidofovir; Cytosine; Injections, Intravenous; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Probenecid; Virus Diseases

1996
Effect of probenecid on the distribution, metabolism, and excretion of cidofovir in rabbits.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:3

    Topics: Administration, Oral; Animals; Antiviral Agents; Autoradiography; Cidofovir; Cytosine; Injections, Intravenous; Kidney; Male; Organophosphonates; Organophosphorus Compounds; Probenecid; Rabbits; Radiography; Tissue Distribution; Uricosuric Agents

1996
Probenecid hypersensitivity in AIDS: a case report.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 80, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Cidofovir; Cytosine; Drug Hypersensitivity; Herpes Simplex; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents

1998
Effect of oral probenecid coadministration on the chronic toxicity and pharmacokinetics of intravenous cidofovir in cynomolgus monkeys.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 44, Issue:2

    Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Injections, Intravenous; Kidney; Macaca fascicularis; Male; Organ Size; Organophosphonates; Organophosphorus Compounds; Probenecid

1998
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:3

    Topics: Adenine; Alanine; Animals; Anion Transport Proteins; Antiviral Agents; Biological Transport; Carrier Proteins; CHO Cells; Cidofovir; Cricetinae; Cytosine; Humans; Kidney; Organophosphate Poisoning; Organophosphonates; Organophosphorus Compounds; Probenecid

2000
Ocular side-effects from systemic HPMPC (Cidofovir) for a non-ocular cytomegalovirus infection.
    American journal of ophthalmology, 2000, Volume: 130, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypotension; Organophosphonates; Organophosphorus Compounds; Probenecid; Uveitis, Anterior

2000
Cidofovir.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Interactions; Drug Therapy, Combination; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents

1998
Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Fluorescent Dyes; Fundulidae; In Vitro Techniques; Kidney Tubules, Proximal; Membrane Transport Proteins; Microscopy, Confocal; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Organophosphonates; Organophosphorus Compounds; Probenecid; Renal Agents; Xenobiotics

2001
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.
    Bone marrow transplantation, 2001, Volume: 28, Issue:9

    Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Evaluation; Eye Infections, Viral; Female; Foscarnet; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Probenecid; Recurrence; Safety; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Uveitis, Anterior; Viral Load; Viremia; Vomiting

2001
Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis.
    Journal of medical virology, 2005, Volume: 75, Issue:2

    Topics: Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Humans; Indoles; Injections, Intralesional; Injections, Intravenous; Lung Neoplasms; Organophosphonates; Papilloma; Probenecid

2005
Intermediate-dose cidofovir without probenecid in the treatment of BK virus allograft nephropathy.
    Pediatric transplantation, 2006, Volume: 10, Issue:1

    Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Child; Cidofovir; Contraindications; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Kidney Transplantation; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Probenecid; Transplantation, Homologous; Tumor Virus Infections; Uricosuric Agents

2006
Tubular transporters and clearance of adefovir.
    European journal of pharmacology, 2006, Jul-01, Volume: 540, Issue:1-3

    Topics: Adenine; Animals; ATP-Binding Cassette Transporters; Biological Transport; Chromatography, High Pressure Liquid; Coproporphyrins; Immunosuppressive Agents; Kidney Tubules; Male; Metabolic Clearance Rate; Models, Biological; Mutation; Organic Anion Transport Protein 1; Organophosphonates; Probenecid; Rats; Rats, Wistar; Time Factors; Uricosuric Agents

2006
[Tubular transporters OAT1 and MRP2 and clearance of adefovir].
    Nephrologie & therapeutique, 2005, Volume: 1, Issue:5

    Topics: Adenine; Animals; Antiviral Agents; Kidney; Male; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Organophosphonates; Probenecid; Rats; Rats, Wistar; Uricosuric Agents

2005
Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2).
    Pharmaceutical research, 2007, Volume: 24, Issue:4

    Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Humans; Kidney; Kinetics; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Organophosphonates; Probenecid; Tenofovir; Transfection

2007
[Diagnosis of interstitial nephropathy caused by BK virus in renal transplantation. Therapeutic management with cidofovir plus probenecid].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2007, Volume: 27, Issue:6

    Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Cytosine; Drug Therapy, Combination; Humans; Kidney Transplantation; Male; Nephritis, Interstitial; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections

2007
Low dosage cidofovir without probenecid as treatment for BK virus hamorrhagic cystitis after hemopoietic stem cell transplant.
    The Pediatric infectious disease journal, 2009, Volume: 28, Issue:1

    Topics: Adolescent; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cystitis; Cytosine; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections

2009
Tenofovir/probenecid combination in HIV/HBV-coinfected patients: how to escape Fanconi syndrome recurrence?
    AIDS (London, England), 2010, Apr-24, Volume: 24, Issue:7

    Topics: Adenine; Fanconi Syndrome; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Probenecid; Secondary Prevention; Tenofovir

2010
[Drug-drug interactions and nephrotoxicity].
    Therapeutische Umschau. Revue therapeutique, 2011, Volume: 68, Issue:1

    Topics: Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents; Antirheumatic Agents; Cidofovir; Cisplatin; Contrast Media; Creatinine; Cytosine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney; Organophosphonates; Probenecid; Risk Factors; Uricosuric Agents

2011
Pharmacokinetics of low-dose cidofovir in kidney transplant recipients with BK virus infection.
    Transplant infectious disease : an official journal of the Transplantation Society, 2013, Volume: 15, Issue:1

    Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antiviral Agents; Area Under Curve; BK Virus; Cidofovir; Cross-Over Studies; Cytosine; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Half-Life; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Probenecid; Tumor Virus Infections; Viremia

2013
Single-dose pharmacokinetics of cidofovir in continuous venovenous hemofiltration.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:4

    Topics: Antiviral Agents; Cidofovir; Critical Illness; Cytosine; Hemofiltration; Humans; Male; Middle Aged; Organophosphonates; Probenecid

2014