Page last updated: 2024-08-16

probenecid and niacin

probenecid has been researched along with niacin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's5 (23.81)18.2507
2000's2 (9.52)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Cupo, MA; Donaldson, WE1
Beninger, RJ; Boegman, RJ; Jhamandas, K; Miranda, AF1
ElĂ­as, MM; Mottino, AD; Ochoa, EJ1
Beninger, RJ; Boegman, RJ; Harris, CA; Jhamandas, K; Miranda, AF; Tanguay, JJ1
Beninger, RJ; Boegman, RJ; Jhamandas, K; Miranda, AF; Sutton, MA1
Frid, S; Lennernas, H; Lindahl, A; Ungell, AL1
FLIPPIN, HF; FOLTZ, EL1
EISENBERG, GM; FLIPPIN, HF; KAPLAN, A; WEISS, W1
MARKKANEN, T; TOIVANEN, A; TOIVANEN, P1
CASTLES, TR; WILLIAMSON, HE1
FARAH, A; FRAZER, M1
Kapadia, R; Kashyap, ML; Kumar, JS; Said, HM; Subramanian, VS1
Duncton, MA; Singh, R1

Reviews

1 review(s) available for probenecid and niacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

20 other study(ies) available for probenecid and niacin

ArticleYear
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Effects of lead and niacin on tryptophan and serotonin metabolism.
    Drug-nutrient interactions, 1988, Volume: 5, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Chickens; Diet; Harmaline; Hydroxyindoleacetic Acid; Lead; Lead Poisoning; Liver; Male; Monoamine Oxidase; Niacin; Probenecid; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tryptophan Oxygenase

1988
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid.
    Neuroscience, 1997, Volume: 78, Issue:4

    Topics: Alanine; Animals; Corpus Striatum; Dopamine; Drug Combinations; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neurons; Neurotoxins; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase

1997
Transepithelial fate of bilirubin in the isolated rat kidney.
    Biochimica et biophysica acta, 1997, Jul-19, Volume: 1336, Issue:1

    Topics: Animals; Area Under Curve; Bilirubin; Epithelium; In Vitro Techniques; Kidney; Male; Niacin; Perfusion; Probenecid; Rats; Rats, Wistar

1997
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: Alanine; Animals; Anticonvulsants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Antagonists; Huntington Disease; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; NADP; Neurons, Afferent; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1998
Quinolinic acid lesion of the nigrostriatal pathway: effect on turning behaviour and protection by elevation of endogenous kynurenic acid in Rattus norvegicus.
    Neuroscience letters, 1999, Mar-05, Volume: 262, Issue:2

    Topics: Alanine; Animals; Corpus Striatum; Excitatory Amino Acid Antagonists; Hydrolases; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Motor Activity; Neurons; Neuroprotective Agents; Niacin; Parkinson Disease, Secondary; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Up-Regulation

1999
No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in the rat.
    AAPS pharmSci, 2000, Volume: 2, Issue:3

    Topics: Acyl Coenzyme A; Animals; Colon; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Ileum; Indoles; Intestinal Absorption; Intestinal Mucosa; Male; Membrane Transport Proteins; Monocarboxylic Acid Transporters; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Niacin; Probenecid; Rats; Rats, Sprague-Dawley

2000
The newer antimicrobial agents.
    American practitioner and digest of treatment, 1953, Volume: 4, Issue:9

    Topics: Anti-Bacterial Agents; Erythromycin; Humans; Niacin; Nicotinic Acids; Penicillins; Probenecid; Sulfonamides

1953
The effect of probenecid on pyrazinamide blood levels and pyrazinamide-induced hyperuricemia.
    Antibiotic medicine & clinical therapy (New York, NY), 1957, Volume: 4, Issue:10

    Topics: Humans; Hyperuricemia; Niacin; Nicotinic Acids; Probenecid; Pyrazinamide; Uric Acid

1957
SPONTANEOUS RENAL EXCRETION OF NICOTINIC ACID, BIOTIN AND VITAMIN B6 AFTER TREATMENT WITH P-(DI-N-PROPYLSULPHAMYL)-BENZOIC ACID.
    Zeitschrift fur Vitamin-, Hormon- und Fermentforschung, 1963, Aug-09, Volume: 13

    Topics: Benzoic Acid; Biotin; Humans; Niacin; Probenecid; Pyridoxine; Rabbits; Renal Elimination; Research; Urine; Vitamin B 6

1963
THE EFFECT OF CHLOROTHIAZIDE ON THE EXCRETION OF URIC ACID AND ELECTROLYTES BY THE CHICKEN.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142

    Topics: Animals; Biological Transport; Chickens; Chlorides; Chlorothiazide; Kidney Function Tests; Niacin; Niacinamide; Pharmacology; Potassium; Poultry; Probenecid; Research; Sodium; Uric Acid; Urine

1963
STUDIES ON THE RATE OF RUNOUT OF N-METHYLNICOTIAMIDE FROM DOG RENAL SLICES.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 145

    Topics: Antimetabolites; Cyanides; Dinitrophenols; Dogs; Iodoacetates; Kidney; Malonates; Metabolism; Niacin; Niacinamide; p-Aminohippuric Acid; Pharmacology; Probenecid; Research; Tetraethylammonium Compounds; Tolazoline

1964
Mammalian colonocytes possess a carrier-mediated mechanism for uptake of vitamin B3 (niacin): studies utilizing human and mouse colonic preparations.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Aug-01, Volume: 305, Issue:3

    Topics: Animals; Biological Availability; Calcium; Calmodulin; Carboxylic Acids; Carrier Proteins; Cell Line; Colon; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Mice; Mice, Inbred C57BL; Monocarboxylic Acid Transporters; Niacin; Niacinamide; Probenecid; Protein-Tyrosine Kinases; Tritium

2013
A one-pot synthesis of tetrazolones from acid chlorides: understanding functional group compatibility, and application to the late-stage functionalization of marketed drugs.
    Organic & biomolecular chemistry, 2016, Oct-04, Volume: 14, Issue:39

    Topics: Aspirin; Azides; Benzimidazoles; Benzoates; Bexarotene; Carboxylic Acids; Chemistry Techniques, Synthetic; Chlorides; Indomethacin; Niacin; Probenecid; Silanes; Telmisartan; Tetrahydronaphthalenes; Tetrazoles

2016