probenecid has been researched along with morphine in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (60.78) | 18.7374 |
| 1990's | 1 (1.96) | 18.2507 |
| 2000's | 13 (25.49) | 29.6817 |
| 2010's | 6 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Korf, J; Westerink, BH | 4 |
| Oka, T; Sawa, A | 1 |
| Ahtee, L; Carlsson, A | 1 |
| Bläsig, J; Gramsch, C; Herz, A | 1 |
| Bensemana, D; Gascon, AL | 1 |
| Murakami, H; Shiomi, H; Takagi, H | 1 |
| Herz, A; Papeschi, R; Theiss, P | 2 |
| Huang, JT; Wajda, IJ | 1 |
| Kuschinsky, K | 1 |
| Odar-Cederlöf, I; Säwe, J; von Bahr, C; Yue, Q | 1 |
| Ahtee, L; Attila, P; Lauhakangas, V; Sipilä, J; Solkinen, A | 1 |
| Chiang, CY; Xiang, XK | 1 |
| Hug, CC | 1 |
| Fujimoto, JM; May, DG; Watrous, WM | 1 |
| Papeschi, R; Theiss, P | 1 |
| Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P | 1 |
| Sladek, NE | 1 |
| Goodlet, I; Sugrue, MF | 1 |
| Buxbaum, DM; Sanders-Busch, E; Yarbrough, GG | 1 |
| Anders, MW; Quebbemann, AJ | 1 |
| Buxbaum, DM; Sanders-Bush, E; Yarbrough, GG | 2 |
| Blake, DE; Haubrich, DR | 1 |
| Bowers, MB; Kleber, HD | 1 |
| Bloom, FE; Costa, E | 1 |
| Sharman, DF | 1 |
| Lyness, WH; Morin, RA | 1 |
| Huff, JW; Reigle, TG | 1 |
| Elmquist, WF; Sawchuk, RJ | 1 |
| Crowe, A | 1 |
| Hammarlund-Udenaes, M; Jonsson, EN; Tunblad, K | 2 |
| Christie, MJ; Hack, SP; Vaughan, CW | 1 |
| Bourasset, F; Scherrmann, JM | 1 |
| Antle, MC; Baimel, C; Baimoukhametova, D; Bains, JS; Bonin, RP; Borgland, SL; Burma, NE; Cahill, CM; Cairncross, ZF; De Koninck, Y; Leduc-Pessah, H; Mousseau, M; Shankara, JV; Stemkowski, PL; Trang, T; Zamponi, GW | 1 |
| de Lange, ECM; Hartman, R; Kervezee, L; Meijer, JH; van den Berg, DJ | 1 |
4 review(s) available for probenecid and morphine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Microdialysis in the study of drug transporters in the CNS.
Topics: Animals; Biological Transport; Brain; Colchicine; Etoposide; Humans; Microdialysis; Morphine; Probenecid; Rhodamines; Zidovudine | 2000 |
47 other study(ies) available for probenecid and morphine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Effects of drugs on the formation of homovanillic acid in the rat retina.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Rats; Retina | 1976 |
Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice.
Topics: Analgesics, Opioid; Animals; Atropine; Brain; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Mice; Mice, Inbred ICR; Morphine; Naloxone; Pargyline; Probenecid; Rats; Serotonin | 1976 |
Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Atropine; Brain; Brain Chemistry; Clozapine; Corpus Striatum; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Male; Morphine; Oxotremorine; Phenylacetates; Physostigmine; Pimozide; Probenecid; Rats; Substantia Nigra; Trihexyphenidyl | 1975 |
Dual action of methadone on 5-HT synthesis and metabolism.
Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine | 1979 |
Changes in striatal dopamine metabolism during precipitated morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzomorphans; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Monoamine Oxidase; Morphine; Naloxone; Probenecid; Rats; Substance Withdrawal Syndrome; Time Factors; Tyramine | 1977 |
Relationship between analgesia and turnover of brain biogenic amines.
Topics: Analgesia; Analgesics; Animals; Biogenic Amines; Brain; Catecholamines; Dronabinol; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Morphine; Probenecid; Rats; Serotonin; Sodium Salicylate | 1978 |
Morphine analgesia and the bulbospinal serotonergic system: increase in concentration of 5-hydroxyindoleacetic acid in the rat spinal cord with analgesics.
Topics: Analgesics; Animals; Hydroxyindoleacetic Acid; Male; Morphine; Narcotic Antagonists; Neurons; Probenecid; Rats; Serotonin; Spinal Cord; Time Factors; Tryptophan Hydroxylase | 1978 |
Effects of morphine on the turnover of brain catecholamines and serotonin in rats-acute morphine administration.
Topics: 3-Methoxy-4-hydroxyphenylethanol; Animals; Biological Transport, Active; Brain; Catecholamines; Dopamine; Homovanillic Acid; Male; Methyltyrosines; Morphine; Norepinephrine; Probenecid; Rats; Serotonin; Time Factors | 1975 |
The effects of morphine on the accumulation of homovanillic and 5-hydroxyindoleacetic acids in the choroid plexus of rats.
Topics: Amino Acids; Animals; Choroid Plexus; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Morphinans; Morphine; Phenylacetates; Probenecid; Rats; Time Factors | 1977 |
Acidic dopamine metabolites in cortical areas of the rat brain: localization and effects of drug.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Morphine; Olfactory Bulb; Oxotremorine; Phenylacetates; Probenecid; Rats; Sulpiride; Thioridazine | 1976 |
Comparison of effects of drugs on dopamine metabolism in the substantia nigra and the corpus striatum of rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chloral Hydrate; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Promethazine; Rats; Receptors, Dopamine; Substantia Nigra | 1976 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
Glucuronidation of codeine and morphine in human liver and kidney microsomes: effect of inhibitors.
Topics: Adult; Amitriptyline; Chloramphenicol; Codeine; Diazepam; Glucuronates; Glucuronosyltransferase; Humans; In Vitro Techniques; Kidney; Kinetics; Microsomes; Microsomes, Liver; Morphine; Oxazepam; Probenecid | 1990 |
The fall of homovanillic acid and 5-hydroxyindoleacetic acid concentrations in brains of mice withdrawn from repeated morphine treatment and their restoration by acute morphine administration.
Topics: Animals; Body Weight; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Morphine; Morphine Dependence; Probenecid; Serotonin; Substance Withdrawal Syndrome; Telencephalon | 1987 |
Does morphine enhance the release of 5-hydroxytryptamine in the rat spinal cord? An in vivo differential pulse voltammetry study.
Topics: Animals; Electrochemistry; Hydroxyindoleacetic Acid; Male; Morphine; Probenecid; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereoisomerism; Tryptophan; Urate Oxidase | 1987 |
Transport of narcotic analgesics by choroid plexus and kidney tissue in vitro.
Topics: Analgesics; Animals; Atmospheric Pressure; Biological Transport, Active; Carbon Isotopes; Choroid Plexus; Chromatography, Paper; Codeine; Dogs; Female; Hexamethonium Compounds; Hydrogen-Ion Concentration; Hydromorphone; In Vitro Techniques; Insulin; Kidney; Levorphanol; Male; Morphine; Nalorphine; Nitrogen; Oxygen; Probenecid; Rabbits; Temperature; Tritium | 1967 |
Mechanism of the renal tubular transport of morphine and morphine ethereal sulfate in the chicken.
Topics: Animals; Biological Transport, Active; Carbon Isotopes; Chickens; Cyanides; Ethers; Kidney Tubules; Morphine; Niacinamide; Piperidines; Probenecid; Sulfates | 1970 |
Proceedings: Turnover of biogenic amines after acute and chronic morphine treatment in rats.
Topics: Acetamides; Animals; Biogenic Amines; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Methyltyrosines; Morphine; Norepinephrine; Probenecid; Rats; Serotonin; Time Factors | 1974 |
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine | 1971 |
Serotonin and dopamine turnover after acute and chronic morphine administration.
Topics: Animals; Brain; Brain Chemistry; Dopamine; Drug Tolerance; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Morphine; Morphine Dependence; Probenecid; Rats; Serotonin; Substance Withdrawal Syndrome | 1974 |
Therapeutic efficacy of cyclophosphamide as a function of inhibition of its metabolism.
Topics: Alkylation; Animals; Azaguanine; Binding, Competitive; Carcinoma 256, Walker; Cyclophosphamide; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Gonadal Steroid Hormones; Male; Meperidine; Mercaptopurine; Metyrapone; Microsomes, Liver; Morphine; Phenacetin; Proadifen; Probenecid; Quinine; Rats | 1972 |
Effects of acutely administered analgesic drugs on rat brain 5-hydroxytryptamine turnover.
Topics: Analgesics; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Morphine; Pargyline; Pentazocine; Probenecid; Rats; Serotonin | 1972 |
Increased serotonin turnover in acutely morphine-treated mice.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Morphine; Probenecid; Serotonin; Time Factors; Tritium; Tryptophan | 1972 |
Renal tubular conjugation and excretion of phenol and p-nitrophenol in the chicken: differing mechanisms of renal transfer.
Topics: Aminohippuric Acids; Animals; Carbon Isotopes; Catechols; Chickens; Female; Glucuronates; Kidney Tubules; Morphine; Nitrophenols; Phenols; Probenecid; Quinine; Sulfates | 1973 |
Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration.
Topics: Animals; Brain Chemistry; Drug Tolerance; Hydroxyindoleacetic Acid; Male; Morphine; Motor Activity; Naloxone; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase | 1973 |
Modification of serotonin metabolism in rat brain after acute or chronic administration of morphine.
Topics: Animals; Brain; Brain Chemistry; Drug Tolerance; Fluorometry; Hydroxyindoleacetic Acid; Male; Morphine; Pargyline; Probenecid; Rats; Reaction Time; Serotonin; Time Factors | 1973 |
Methadone increases mouse brain 5-hydroxyindoleacetic acid.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Methadone; Mice; Morphine; Pargyline; Probenecid; Serotonin; Stimulation, Chemical | 1971 |
The effects of drugs on serotonergic nerve terminals.
Topics: Animals; Brain; Catecholamines; Cerebellum; Histocytochemistry; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Lysergic Acid Diethylamide; Microscopy, Electron; Monoamine Oxidase Inhibitors; Morphine; Nerve Endings; Norepinephrine; Pargyline; Probenecid; Rats; Serotonin; Synapses; Time Factors; Tryptophan | 1971 |
Increased serotonin turnover in the acutely morphine treated rat.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Male; Morphine; Organ Size; Pargyline; Probenecid; Rats; Serotonin; Time Factors | 1971 |
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine | 1966 |
Potentiation of morphine analgesia after pretreatment with probenecid or sulfinpyrazone.
Topics: Analgesia; Animals; Benzoquinones; Dose-Response Relationship, Drug; Drug Synergism; Male; Morphine; Probenecid; Quinones; Rats; Rats, Inbred Strains; Sulfinpyrazone | 1983 |
Effects of morphine and other centrally acting drugs on 3,4-dihydroxyphenylethylene glycol sulfate (DOPEG-SO4) in rat brain.
Topics: Animals; Brain; Brain Chemistry; Desipramine; Dextroamphetamine; Glycols; Male; Methoxyhydroxyphenylglycol; Morphine; Norepinephrine; Probenecid; Rats; Reserpine; Spectrometry, Fluorescence | 1980 |
The influence of P-glycoprotein on morphine transport in Caco-2 cells. Comparison with paclitaxel.
Topics: Analgesics, Opioid; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Buthionine Sulfoximine; Caco-2 Cells; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Genistein; Glutathione; Humans; Indomethacin; Morphine; Paclitaxel; Probenecid; Progesterone; Time Factors; Verapamil | 2002 |
Morphine blood-brain barrier transport is influenced by probenecid co-administration.
Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Drug Interactions; Male; Microdialysis; Morphine; Probenecid; Rats; Rats, Sprague-Dawley | 2003 |
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines | 2003 |
An integrated model for the analysis of pharmacokinetic data from microdialysis experiments.
Topics: Animals; Blood-Brain Barrier; Microdialysis; Models, Biological; Morphine; Pharmacokinetics; Probenecid; Rats | 2004 |
Carrier-mediated processes at several rat brain interfaces determine the neuropharmacokinetics of morphine and morphine-6-beta-D-glucuronide.
Topics: Algorithms; Animals; Blood-Brain Barrier; Brain; Carrier Proteins; Male; Microdialysis; Models, Biological; Morphine; Morphine Derivatives; Narcotics; Permeability; Probenecid; Rats; Rats, Wistar; Renal Agents; Spectrophotometry, Ultraviolet | 2006 |
Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents.
Topics: Adenosine Triphosphate; Animals; Apyrase; Behavior, Animal; Blotting, Western; Cell Culture Techniques; Coculture Techniques; Connexins; Mefloquine; Mice; Microglia; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nerve Tissue Proteins; Neurons; Nociception; Posterior Horn Cells; Probenecid; Rats; Substance Withdrawal Syndrome | 2017 |
Diurnal variation in the pharmacokinetics and brain distribution of morphine and its major metabolite.
Topics: Analgesics, Opioid; Animals; Brain; Male; Metabolic Clearance Rate; Morphine; Morphine Derivatives; Probenecid; Quinolines; Rats; Rats, Wistar | 2017 |