Page last updated: 2024-08-16

probenecid and metronidazole

probenecid has been researched along with metronidazole in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (15.00)	18.7374
1990's	2 (10.00)	18.2507
2000's	7 (35.00)	29.6817
2010's	8 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Laird, SM; Roy, RB	1
van Gelderen, CJ	1
Gut, JP	1
Nye, FJ	1
Blackwell, AL; Singh, G; Thomas, PD	1
E, L; Liu, H; Wang, D; Wu, X; Yu, L	1

Reviews

1 review(s) available for probenecid and metronidazole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for probenecid and metronidazole

Article	Year
'One-visit' therapy for pelvic inflammatory disease. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Aug-09, Volume: 58, Issue:6 Topics: Acute Disease; Blood Sedimentation; Drug Therapy, Combination; Escherichia coli; Female; Fever; Humans; Leukocyte Count; Leukorrhea; Metronidazole; Nitroimidazoles; Ornidazole; Patient Compliance; Probenecid; Sulfadoxine; Sulfamethazine; Sulfanilamides; Time Factors; Vaginitis	1980

Article

Year

'One-visit' therapy for pelvic inflammatory disease.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Aug-09, Volume: 58, Issue:6

Topics: Acute Disease; Blood Sedimentation; Drug Therapy, Combination; Escherichia coli; Female; Fever; Humans; Leukocyte Count; Leukorrhea; Metronidazole; Nitroimidazoles; Ornidazole; Patient Compliance; Probenecid; Sulfadoxine; Sulfamethazine; Sulfanilamides; Time Factors; Vaginitis

1980

Other Studies

18 other study(ies) available for probenecid and metronidazole

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Comparison of procaine penicillin alone with ampicillin plus probenecid in the treatment of gonorrhoea in the male. The British journal of venereal diseases, 1974, Volume: 50, Issue:2 Topics: Administration, Oral; Alcohol Drinking; Ampicillin; Drug Therapy, Combination; England; Female; Gonorrhea; Humans; Injections, Intramuscular; Male; Metronidazole; Penicillin G Procaine; Probenecid; Trichomonas Vaginitis; Urethritis	1974
[Changes in indications for drugs]. La Revue du praticien, 1980, Feb-01, Volume: 30, Issue:7 Topics: Amantadine; Clofibrate; Colchicine; Drug Therapy; Female; Gout; Humans; Levamisole; Metronidazole; Middle Aged; Probenecid; Sulfinpyrazone	1980
Primary abdominal actinomycosis. The Journal of infection, 1993, Volume: 27, Issue:1 Topics: Abdominal Muscles; Actinomycosis; Aged; Female; Humans; Laparotomy; Metronidazole; Penicillin G; Penicillin V; Probenecid	1993
An audit of the problems in management of patients with gonorrhoea. International journal of STD & AIDS, 1997, Volume: 8, Issue:3 Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Bacteriological Techniques; Ciprofloxacin; Drug Therapy, Combination; Erythromycin; Female; Gonorrhea; Humans; Male; Metronidazole; Oxytetracycline; Penicillins; Probenecid; Renal Agents; Reproducibility of Results	1997
Uptake of metronidazole by human gingival fibroblasts. Journal of periodontology, 2009, Volume: 80, Issue:6 Topics: Adenine; Adjuvants, Pharmaceutic; Adolescent; Anti-Infective Agents; Cation Transport Proteins; Cells, Cultured; Chromatography, High Pressure Liquid; Diffusion; Extracellular Fluid; Fibroblasts; Gingiva; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Male; Membrane Transport Modulators; Metronidazole; Microbial Sensitivity Tests; Probenecid; Temperature; Time Factors	2009