probenecid has been researched along with kynurenine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beal, MF; MacGarvey, U; Miller, JM | 1 |
| Beal, MF; Nozaki, K | 1 |
| Beal, MF; MacGarvey, U; Miller, J; Vécsei, L | 1 |
| Altagracia, M; Gonzalez, L; Kravzov, J; Ordaz, H; Ríos, C; Santamaría, A; Solís, F | 1 |
| Altagracia, M; González-Reynoso, L; Kravzov, J; Ordaz-Moreno, J; Ríos, C; Santamaría, A; Solís-Hernández, F | 1 |
| Beal, MF; Vécsei, L | 1 |
| Beninger, RJ; Boegman, RJ; Jhamandas, K; Miranda, AF | 1 |
| Beninger, RJ; Boegman, RJ; Harris, CA; Jhamandas, K; Miranda, AF; Tanguay, JJ | 1 |
| Beninger, RJ; Boegman, RJ; Jhamandas, K; Miranda, AF; Sutton, MA | 1 |
| Emanuelsson, C; Erhardt, S; Geyer, M; Schwieler, L | 1 |
| Farkas, T; Janáky, T; Kis, Z; Marosi, M; Németh, H; Robotka, H; Rózsa, E; Somlai, C; Toldi, J; Vécsei, L | 1 |
| Erhardt, S; Linderholm, KR; Nilsson, LK | 1 |
| Chadaide, Z; Fenyo, R; Knyihár-Csillik, E; Krisztin-Péva, B; Mihály, A; Németh, H; Toldi, J; Vécsei, L | 1 |
| Chadaide, Z; Fenyo, R; Knyihár-Csillik, E; Krisztin-Péva, B; Németh, H; Toldi, J; Vécsei, L | 1 |
| Agoston, M; Gigler, G; Robotka, H; Rózsa, E; Sas, K; Szénási, G; Toldi, J; Vécsei, L | 1 |
| Agoston, M; Farkas, T; Gigler, G; Kis, Z; Marosi, M; Robotka, H; Rózsa, E; Sas, K; Szénási, G; Toldi, J; Vécsei, L | 1 |
| Bohár, Z; Fülöp, F; Párdutz, A; Tajti, J; Toldi, J; Vámos, E; Varga, H; Vécsei, L | 1 |
| Carrillo-Mora, P; Fortoul-van Der Goes, TI; Méndez-Cuesta, LA; Pérez-De La Cruz, V; Santamaría, A | 1 |
| Carlà, V; Cavone, L; Cosi, C; Cozzi, A; Mannaioni, G; Maratea, D; Moroni, F; Sili, M | 1 |
| Honjo, H; Iwamoto, K; Uwai, Y | 1 |
| Aguilera, P; Barragán-Iglesias, P; Bravo-Hernández, M; Cervantes-Durán, C; González-Esquivel, DF; Granados-Soto, V; Pérez-Severiano, F; Pineda-Farias, JB; Ríos, C | 1 |
| Colín-González, AL; Santamaría, A | 1 |
| Darlington, LG; Forrest, CM; Khalil, OS; McNair, K; Pisar, M; Stone, TW | 1 |
1 review(s) available for probenecid and kynurenine
| Article | Year |
|---|---|
Probenecid: an emerging tool for neuroprotection.
Topics: Animals; Brain; Drug Interactions; Humans; Kynurenine; Models, Neurological; Nervous System Diseases; Neuroprotective Agents; Probenecid; Signal Transduction | 2013 |
22 other study(ies) available for probenecid and kynurenine
| Article | Year |
|---|---|
The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations.
Topics: Animals; Corpus Striatum; Dialysis; Extracellular Space; Kynurenic Acid; Kynurenine; Male; Nervous System; Probenecid; Rats; Rats, Sprague-Dawley | 1992 |
Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Kynurenic Acid; Kynurenine; N-Methylaspartate; Probenecid; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains | 1992 |
Kynurenine and probenecid inhibit pentylenetetrazol- and NMDLA-induced seizures and increase kynurenic acid concentrations in the brain.
Topics: Analysis of Variance; Animals; Brain; Cerebral Cortex; Corpus Striatum; Diazepam; Dose-Response Relationship, Drug; Kynurenic Acid; Kynurenine; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Probenecid; Seizures | 1992 |
Kynurenine and probenecid prevent quinolinic acid-induced neurotoxicity in rat corpus striatum.
Topics: Animals; Brain Diseases; gamma-Aminobutyric Acid; Kynurenine; Male; Neostriatum; Probenecid; Quinolinic Acid; Rats; Rats, Wistar | 1994 |
Systemic DL-kynurenine and probenecid pretreatment attenuates quinolinic acid-induced neurotoxicity in rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Kynurenine; Male; Motor Activity; Probenecid; Quinolinic Acid; Rats; Rats, Wistar | 1996 |
Huntington's disease, behavioral disturbances, and kynurenines: preclinical findings and therapeutic perspectives.
Topics: Animals; Disease Models, Animal; Humans; Huntington Disease; Kynurenine; Papio; Probenecid; Rats; Receptors, Glutamate; Social Behavior Disorders | 1996 |
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid.
Topics: Alanine; Animals; Corpus Striatum; Dopamine; Drug Combinations; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neurons; Neurotoxins; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 1997 |
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid.
Topics: Alanine; Animals; Anticonvulsants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Antagonists; Huntington Disease; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; NADP; Neurons, Afferent; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Quinolinic acid lesion of the nigrostriatal pathway: effect on turning behaviour and protection by elevation of endogenous kynurenic acid in Rattus norvegicus.
Topics: Alanine; Animals; Corpus Striatum; Excitatory Amino Acid Antagonists; Hydrolases; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Motor Activity; Neurons; Neuroprotective Agents; Niacin; Parkinson Disease, Secondary; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Up-Regulation | 1999 |
Endogenous kynurenic acid disrupts prepulse inhibition.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Butyrates; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Haloperidol; Kynurenic Acid; Kynurenine; Male; Neural Inhibition; Probenecid; Rats; Reflex, Startle | 2004 |
Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study.
Topics: Animals; Anticonvulsants; Behavior, Animal; Drug Synergism; Electrophysiology; Hippocampus; Kynurenine; Male; Maze Learning; Pentylenetetrazole; Probenecid; Pyramidal Cells; Rats; Rats, Wistar; Seizures | 2004 |
Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons.
Topics: Acoustic Stimulation; Action Potentials; Analysis of Variance; Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Inhibition, Psychological; Kynurenine; Male; Mesencephalon; Neurons; Nicotine; Probenecid; Rats; Rats, Sprague-Dawley; Reflex, Startle; Statistics, Nonparametric | 2006 |
Kynurenine in combination with probenecid mitigates the stimulation-induced increase of c-fos immunoreactivity of the rat caudal trigeminal nucleus in an experimental migraine model.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Genes, fos; Immunohistochemistry; Kynurenine; Male; Migraine Disorders; Neurons; Nitroglycerin; Probenecid; Rats; Rats, Wistar; Trigeminal Caudal Nucleus; Vasodilator Agents | 2007 |
Prevention of electrical stimulation-induced increase of c-fos immunoreaction in the caudal trigeminal nucleus by kynurenine combined with probenecid.
Topics: Adjuvants, Pharmaceutic; Afferent Pathways; Analgesics; Animals; Blood-Brain Barrier; Disease Models, Animal; Drug Synergism; Electric Stimulation; Immunohistochemistry; Kynurenine; Male; Migraine Disorders; Neurons, Afferent; Nitroglycerin; Nociceptors; Probenecid; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Synaptic Transmission; Treatment Outcome; Trigeminal Caudal Nucleus; Vasodilator Agents | 2007 |
Neuroprotection achieved in the ischaemic rat cortex with L-kynurenine sulphate.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Fluoresceins; Kynurenine; Neuroprotective Agents; Organic Anion Transporters; Organic Chemicals; Probenecid; Rats; Rats, Wistar; Vertebral Artery | 2008 |
Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus.
Topics: Adjuvants, Pharmaceutic; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Infarction, Middle Cerebral Artery; Kynurenic Acid; Kynurenine; Long-Term Potentiation; Male; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Probenecid; Rats; Rats, Wistar | 2008 |
l-kynurenine combined with probenecid and the novel synthetic kynurenic acid derivative attenuate nitroglycerin-induced nNOS in the rat caudal trigeminal nucleus.
Topics: Animals; Central Nervous System Agents; Cervical Vertebrae; Drug Synergism; Kynurenic Acid; Kynurenine; Male; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitroglycerin; Probenecid; Quinolones; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors; Trigeminal Nuclei | 2009 |
Protective effect of systemic L-kynurenine and probenecid administration on behavioural and morphological alterations induced by toxic soluble amyloid beta (25-35) in rat hippocampus.
Topics: Amyloid beta-Peptides; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Glial Fibrillary Acidic Protein; Hippocampus; Kynurenine; Male; Maze Learning; Motor Activity; Neuroprotective Agents; Peptide Fragments; Probenecid; Rats; Rats, Wistar; Statistics, Nonparametric; Time Factors | 2010 |
G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast.
Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Gene Expression; Inflammation; Kynurenic Acid; Kynurenine; Male; Mice; Neuroglia; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Probenecid; Purinones; Receptors, G-Protein-Coupled; Spinal Cord; Tryptophan | 2011 |
Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3.
Topics: Animals; Biological Transport; Estrone; Humans; Kinetics; Kynurenic Acid; Kynurenine; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Probenecid; Quinolinic Acid; Xenopus laevis | 2012 |
The L-kynurenine-probenecid combination reduces neuropathic pain in rats.
Topics: Animals; Drug Therapy, Combination; Female; Hyperalgesia; Kynurenine; Motor Activity; Neuralgia; Pain Measurement; Probenecid; Rats; Rats, Wistar; Spinal Cord | 2013 |
Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine.
Topics: Adjuvants, Pharmaceutic; Animals; Doublecortin Domain Proteins; Doublecortin Protein; Female; Galantamine; Gene Expression Regulation; Gestational Age; Hippocampus; In Vitro Techniques; Kynurenine; Kynurenine 3-Monooxygenase; Long-Term Potentiation; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neuronal Plasticity; Neuropeptides; Nootropic Agents; Pregnancy; Prenatal Exposure Delayed Effects; Probenecid; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glutamate | 2015 |