probenecid has been researched along with homovanillic acid in 206 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 190 (92.23) | 18.7374 |
| 1990's | 9 (4.37) | 18.2507 |
| 2000's | 4 (1.94) | 29.6817 |
| 2010's | 1 (0.49) | 24.3611 |
| 2020's | 2 (0.97) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Deguchi, T; Hosoya, K; Kang, YS; Mori, S; Ohtsuki, S; Takanaga, H; Terasaki, T | 1 |
| Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T | 1 |
| Korf, J; Westerink, BH | 5 |
| Butler, IJ; Koslow, SH | 1 |
| Scally, MC; Ulus, I; Wurtman, RJ | 1 |
| Davis, KL; Goodwin, FK; Gordon, EK; Hollister, LE | 1 |
| Hurwic, MJ; Klutch, A; Sverd, J; Winsberg, BG | 1 |
| Callaghan, N; Curzon, G; Kantamaneni, BD; Murnaghan, D; Sullivan, PA | 1 |
| Dement, WC; Guilleminault, C; Phillips, R | 1 |
| Cook, A; Hurwic, M; Klutch, A; Nidzgorski, F; Winsberg, B | 1 |
| Barchas, JD; Dement, WC; Faull, K; Foutz, AS; Holman, RB | 1 |
| Dedek, J; Gomeni, R; Korf, J | 1 |
| Campanella, G; Carrieri, P; Mandarini, A; Orefice, G; Rossi, V | 1 |
| Besset, A; Billiard, M; Passouant, P; Renaud, B | 1 |
| Bacopoulos, NG; Heninger, GR; Roth, RH | 1 |
| Baker, HF; Ridley, RM | 1 |
| Curzon, G | 1 |
| Sishta, SK; Templer, DI | 1 |
| Chase, TN; Ebert, MH; Kartzinel, R | 1 |
| Billiard, M; Dement, WC; Guilleminault, C | 1 |
| Angel, C; Deluca, DC; Murphree, OD | 2 |
| Bowers, MB; Moore, D; Tarsy, D | 1 |
| Bowers, MB; Study, RE | 1 |
| Aronoff, A; de la Vega, CE; Garelis, E; Lal, S; Sourkes, TL; Young, SN | 1 |
| Bowers, MB; Caparulo, BK; Cohen, DJ; Shaywitz, BA | 2 |
| Bowers, MB; Caparulo, B; Cohen, DJ; Shaywitz, BA; Young, JG | 1 |
| Butler, IJ; Caprioli, RM; Koslow, SH; Seifert, WE; Singer, HS | 1 |
| Deshmukh, VD; Haufrect, DB; Jacob, RH; Mathew, NT; Meyer, JS; Morrell, RM; Perez, FI; Welch, KM | 1 |
| Barnaba, A; Di Reda, L; Livrea, P; Puca, FM | 1 |
| Bunney, W; Gillin, JC; Jimerson, D; Karoum, F; Van Kammen, D; Wyatt, RJ | 1 |
| Korf, J; Van Praag, HM; Van Scheyen, JD | 1 |
| Korf, J; Van der Poel, FW; Van Praag, HM | 1 |
| Courjon, J; Dalery, J; de Villard, R; Mauguière, F | 1 |
| Fuenmayor, LD | 1 |
| Baumes, R; Dedek, J; Gomeni, R; Korf, J; Tien-Duc, N | 1 |
| Hefti, F | 1 |
| Bläsig, J; Gramsch, C; Herz, A | 1 |
| Bowers, MB; Heninger, GR | 1 |
| Aizenstein, ML; Korf, J | 1 |
| Benezech, M; Bioulac, B; Noël, B; Renaud, B; Roche, D | 2 |
| Goodwin, FK; Post, RM | 4 |
| van Praag, HM | 3 |
| Herz, A; Papeschi, R; Theiss, P | 2 |
| Bowers, MB; Cohen, DJ; Shaywitz, BA | 1 |
| Fenstermacher, JD; Kessler, JA; Patlak, CS | 1 |
| Gordon, EK; Kessler, JA; Kopin, IJ; Reid, JL | 1 |
| Gordon, EK; Kopin, IJ; Markey, SP; Sherman, RL | 1 |
| Black, KE; Kopanda, RT; Post, RM | 1 |
| Goodwin, K; Post, RM | 1 |
| Huang, JT; Wajda, IJ | 2 |
| Karoum, F; Neff, NH; Wyatt, RJ | 1 |
| Marttila, R; Rinne, UK; Sonninen, V | 2 |
| Ahtee, L; Saarnivaara, L; Ylitalo, P | 1 |
| Broch, OJ | 1 |
| Bowers, MB; Extein, I; Roth, RH; Van Woert, M | 1 |
| Bowers, MB | 6 |
| Da Prada, M; Keller, HH | 1 |
| Chazot, G; Guard, O; Renaud, B | 1 |
| Sethy, VH; Van Woert, MH | 1 |
| Chase, TN; Shoulson, I | 1 |
| Klatzo, I; Mrsulja, BB; Mrsulja, BJ; Spatz, M | 1 |
| Argenta, G; Casati, C; Dolfini, E; Jori, A | 1 |
| Glick, SD; Watson, E; Wilk, S | 1 |
| Travis, B; Watson, E; Wilk, S | 1 |
| Bonilla, E; Hernandez, H; Ryder, S | 1 |
| Carpenter, WT; Fink, E; Goodwin, FK; Post, RM | 1 |
| Korf, J; Praag, HM; Schut, T | 1 |
| Kuschinsky, K | 1 |
| Papeschi, R; Theiss, P | 2 |
| Muizelaar, JP; Oberink, JI | 1 |
| Gordon, EK; Kopin, IJ; Oliver, J | 1 |
| Minderhoud, JM; Teelken, AW; van Woerkom, CA; Vecht, CJ | 1 |
| Grasdijk, L; Korf, J; Westerink, BH | 1 |
| Channabasavanna, SM; Khanna, S; Rao, BS; Reddy, PL; Subhash, MN | 1 |
| Abed, WT | 1 |
| Csernansky, JG; Faull, KF; Jibson, M | 1 |
| Miyamoto, JK; Terashima, S; Uezu, E | 1 |
| Curzon, G; Hutson, PH; Kantamaneni, BD; Sahakian, BJ; Sarna, GS | 1 |
| De La Riva, CF; Yeo, JA | 1 |
| Fuller, RW; Molloy, BB; Snoddy, HD | 1 |
| MacMillan, V | 1 |
| Ahtee, L; Attila, P; Lauhakangas, V; Sipilä, J; Solkinen, A | 1 |
| Artru, F; Deleuze, R; Gagnieu, MC; Jourdan, C; Quincy, C; Renaud, B | 1 |
| Emanuelsson, BM; Paalzow, LK; Walléus, H; Widerlöv, E | 1 |
| Bovell, M; Chung, T; Leake, J; MacMillan, V | 1 |
| Emanuelsson, BM; Paalzow, L; Sunzel, M | 1 |
| Adams, F; Becker, JB; Robinson, TE | 1 |
| Bednar, I; Forsberg, G; Qureshi, GA; Södersten, P | 1 |
| Bermúdez, M; Fuenmayor, LD | 1 |
| Gibson, CJ; Growdon, JH; Logue, M | 1 |
| Seegal, RF | 1 |
| Barchas, JD; Berger, PA; Faull, KF; Stahl, SM; Thiemann, S | 1 |
| Trulson, ME; Ulissey, MJ | 1 |
| Curzon, G; Hutson, PH; Kennett, GA; Marcou, M; Sarna, GS | 1 |
| Kikkert, RJ; Westerink, BH | 1 |
| Ballenger, JC; Linnoila, M; Post, RM; Rubinow, DR; Uhde, TW | 1 |
| Dalmaz, Y; De Haut, M; Favre, R; Peyrin, L; Tavitian, E | 1 |
| Korf, J; Lakke, JP; Minderhoud, JM; Schut, T; van Praag, HM | 1 |
| Chase, TN; Ng, LK | 1 |
| Carlsson, A; Davis, JN | 1 |
| Chase, TN; Gordon, EK; Ng, LK | 1 |
| Chase, TN | 4 |
| Garelis, E; Lal, S; Sourkes, TL; Young, SN | 1 |
| Neff, NH; Sampath, SS | 1 |
| Chase, TN; Cramer, H; Ng, LK | 1 |
| Laaksonen, H; Riekkinen, P; Rinne, UK; Sonninen, V | 1 |
| Delgado, J; Foster, FG; Kupfer, DJ; Weiss, BL | 1 |
| Bowers, MB; Extein, I; Roth, RH | 1 |
| Bowers, M; Cohen, DJ; Johnson, WT; Shaywitz, BA | 1 |
| Korf, J; Lakke, JP; Nienhuis, RJ; Schut, D; van Praag, HM | 1 |
| Sjöström, R | 2 |
| Korf, J; van Praag, HM | 1 |
| Barbeau, A | 1 |
| Goodwin, FK; Sack, RL | 1 |
| Andersson, H; Hagne, I; Roos, BE | 1 |
| Bowers, MB; Extein, I; Korf, J; Roth, RH | 1 |
| Rinne, UK; Siirtola, T; Sonninen, V | 1 |
| Riekkinen, P; Rinne, UK; Sonninen, V | 1 |
| Andersson, H; Roos, BE; von Essen, C | 1 |
| Anggård, E; Fyrö, B; Sedvall, G; Sjöquist, B | 1 |
| Dols, LC; Flentge, F; Korf, J; Schut, T; van Praag, HM | 1 |
| Caccia, S; Cecchetti, G; Garattini, S; Jori, A | 1 |
| Bartholini, G; Keller, HH; Pletscher, A | 1 |
| Munkvad, I; Papeschi, R; Randrup, A | 1 |
| Angrist, BM; Gershon, S; Wilk, S | 1 |
| Chase, TN; Glaubiger, GA; Woods, AC | 1 |
| Gottfries, CG | 1 |
| Gottfries, CG; Kjällquist, A; Pontén, U; Roos, BE; Sundbärg, G | 1 |
| Watson, E; Wilk, S | 1 |
| Engström, G; Svensson, TH; Waldeck, B | 1 |
| Chen, YF | 2 |
| Bowers, MB; Heninger, GR; Meltzer, HY; Sternberg, D | 1 |
| Eujita, Y; Kawano, T; Mori, K; Tsujimura, M | 1 |
| Wood, JH | 1 |
| Bunney, WE; Goodwin, FK; Jimerson, DC; Post, RM | 1 |
| Bowers, MB; Caparulo, BK; Cohen, DJ; Heninger, GR; Leckman, JF; Shaywitz, BA | 1 |
| Castells, S; Hurwic, M; Perel, JM; Sverd, J; Winsberg, BG | 1 |
| Dekoninck, WJ; Lefèvre, A; Mendlewicz, J; Vanderheyden, JE | 1 |
| Bowers, MB; Cohen, DJ; Leckman, JF; Shaywitz, BA; Young, JG | 1 |
| Airaksinen, MM; Leino, E; MacDonald, E; Riekkinen, PJ | 1 |
| Bowers, MB; Leckman, JF; Sturges, JS | 1 |
| Mendlewicz, J; Noel, G; Vanderheyden, JE | 2 |
| Barchas, JD; Berger, PA; Faull, KF; Kraemer, HC | 1 |
| Radulovacki, M; Wojcik, WJ | 1 |
| Barchas, JD; Berger, PA; Davis, BM; Davis, KL; Faull, KF; Hollister, LE; Hsieh, JY; Mathé, AA; Rothpearl, AB | 1 |
| Moore, KE; Nielsen, JA | 1 |
| Growdon, JH; Hefti, F; Logue, M; Melamed, E; Wurtman, RJ | 1 |
| Barchas, JD; Dement, WC; Faull, KF; Foutz, AS; Holman, RB | 1 |
| Airaksinen, EM; Leino, E | 1 |
| Korf, J; van den Burg, W; van den Hoofdakker, RH | 1 |
| Elghozi, JL; Le Quan-Bui, KH; Mignot, E | 1 |
| Buchle, AM; Fehr, B; Feldtrauer, JJ; Stoecklin, K; Waldmeier, PC | 1 |
| Cowdry, RW; Ebert, MH; Goodwin, FK; Post, RM; van Kammen, DP | 1 |
| Cramer, H; Renaud, B; Warter, JM | 1 |
| Gagnieu, MC; Guardiola, P; Menouni-Foray, V; Quincy, C; Renaud, B | 1 |
| Curzon, G; Hutson, PH; Kantamaneni, BD; Sarna, GS | 1 |
| Curzon, G; Hutson, PH; Sarna, GS | 2 |
| Warnhoff, M | 1 |
| Asberg, M; Bertilsson, L; Mårtensson, B | 1 |
| Ebert, MH; Gwirtsman, HE; Kaye, WH; Weiss, SR | 1 |
| Himmel, CD; Trulson, ME | 1 |
| Amaral, R; Conçalves, AF; Cunha, L; Diniz, M; Oliveira, CR; Pio-Abreu, J | 1 |
| Bowers, MB; Gold, BI; Roth, RH | 1 |
| Barchas, JD; Berger, PA; Davis, KL; Faull, KF; Hollister, LE | 1 |
| Amaral, R; Cunha, L; Dinis, M; Gonçalves, AF; Oliveira, C | 1 |
| Faull, KF; Guilleminault, C | 1 |
| Anderson, PJ; Barchas, JD; Berger, PA; Davis, KL; Faull, KF; Kilkowski, J; Kraemer, H | 1 |
| Broch, OJ; Francis, LP; Monge, P; Solheim, E | 1 |
| Cano, J; Machado, A; Venero, JL | 1 |
| Altagracia, M; Kravzov, J; López-Naranjo, F; Rios, C | 1 |
| Altagracia, M; Kravzov, J; Rios, C; Rojas, P | 1 |
| Amin, F; Davidson, M; Kahn, RS; Kahn, T; Knott, PJ; Stroe, AE | 1 |
| Beagles, KE; Heyes, MP; Morishige, GM; Morrison, PF | 1 |
| Eisenhofer, G; Harvey-White, J; He, LP; Hrycyna, C; Kopin, IJ; Lamensdorf, I; Nechushtan, A; Rojas, E; Tjurmina, O | 1 |
| Chen, W; Gan, J; Gu, X; Humphreys, WG; Lai, Y; Marathe, P; Mcnaney, CA; Nelson, DM; Oliveira, RV; Reily, MD; Shen, H; Shipkova, PA; Su, C; Zhang, Y | 1 |
| Ahmad, A; Galetin, A; Jacobs, F; Kunze, A; Ogungbenro, K; Rostami-Hodjegan, A; Snoeys, J | 1 |
| Hao, J; Lai, Y; Liu, R; Zhao, X | 1 |
11 review(s) available for probenecid and homovanillic acid
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Studies of amine metabolites in affective illness and in schizophrenia: a comparative analysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depression; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mandelic Acids; Methoxyhydroxyphenylglycol; Norepinephrine; Probenecid; Remission, Spontaneous; Schizophrenia; Serotonin; Tranquilizing Agents | 1975 |
Therapy-resistant depressions: biochemical and pharmacological considerations.
Topics: Adjustment Disorders; Antidepressive Agents; Brain; Depression; Drug Resistance; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase; Norepinephrine; Probenecid; Receptors, Drug; Serotonin | 1975 |
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan | 1974 |
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors | 1974 |
[Biochemical and clinical correlations in Parkinson's disease].
Topics: Brain; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Movement Disorders; Norepinephrine; Parkinson Disease; Probenecid | 1972 |
Central dopamine function in affective illness: evidence from precursors, enzyme inhibitors, and studies of central dopamine turnover.
Topics: Adult; Affective Symptoms; Anger; Bipolar Disorder; Central Nervous System; Depression; Diagnosis, Differential; Dihydroxyphenylalanine; Dopamine; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Male; Methyltyrosines; Middle Aged; Norepinephrine; Picolinic Acids; Probenecid; Psychiatric Nursing; Psychotic Disorders; Time Factors; Tyrosine | 1974 |
Neurochemical analysis of cerebrospinal fluid.
Topics: Blood-Brain Barrier; Cerebrospinal Fluid; Cyclic AMP; Cyclic GMP; Endorphins; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hypothalamic Hormones; Neurotransmitter Agents; Norepinephrine; Pituitary Hormones; Probenecid | 1980 |
[Use of the probenecid test for the diagnosis and treatment of Parkinsonism. Review of the literature and personal experience (author's transl)].
Topics: Aged; Brain; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Neural Pathways; Parkinson Disease, Secondary; Probenecid; Serotonin | 1980 |
Cerebrospinal fluid probenecid studies: a reinterpretation.
Topics: Biological Transport; Brain; Depressive Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Probenecid; Psychotic Disorders; Schizophrenia; Serotonin | 1983 |
CSF monoamine metabolites, depression, and suicide.
Topics: Aggression; Analysis of Variance; Biogenic Amines; Depressive Disorder; Dexamethasone; Homicide; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Personality Inventory; Probenecid; Suicide | 1984 |
13 trial(s) available for probenecid and homovanillic acid
| Article | Year |
|---|---|
Neurotransmitter metabolites in the cerebrospinal fluid of man following physostigmine.
Topics: Adult; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neurotransmitter Agents; Physostigmine; Probenecid; Scopolamine | 1977 |
Tardive dyskinesia: a clinical test of the supersensitivity hypothesis.
Topics: Adult; Aged; Clinical Trials as Topic; Cyclic AMP; Depression; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Receptors, Dopamine; Schizophrenia | 1979 |
Controlled study comparing nomifensine and clomipramine in unipolar depression, using the probenecid technique.
Topics: Adult; Clinical Trials as Topic; Clomipramine; Depression; Dibenzazepines; Double-Blind Method; Female; Homovanillic Acid; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; Probenecid | 1977 |
Fenfluramine in man: hypophagia associated with diminished serotonin turnover.
Topics: Adult; Appetite; Body Weight; Clinical Trials as Topic; Depression, Chemical; Dopamine; Feeding and Eating Disorders; Female; Fenfluramine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Placebos; Probenecid; Serotonin | 1975 |
Effect of ECT and imipramine treatment on the concentration of 5-hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) in the cerebrospinal fluid of depressed patients.
Topics: Adult; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Middle Aged; Phenylacetates; Probenecid | 1975 |
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Phenylacetates; Placebos; Probenecid; Stimulation, Chemical; Substance-Related Disorders; Tryptophan | 1974 |
5-Hydroxyindole acetic acid and homovanillic acid in cerebrospinal fluid in manic-depressive psychosis and the effect of probenecid treatment.
Topics: Adult; Age Factors; Aged; Bipolar Disorder; Body Weight; Clinical Trials as Topic; Female; Half-Life; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Male; Middle Aged; Phenylacetates; Probenecid; Protein Binding; Regression Analysis; Statistics as Topic; Time Factors | 1973 |
Amitriptyline in man: decreased formation of central 5-hydroxyindoleacetic acid.
Topics: Aged; Amitriptyline; Clinical Trials as Topic; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Serotonin; Tryptophan | 1974 |
Serotonin metabolism in depression: clinical application of the probenecid test.
Topics: 5-Hydroxytryptophan; Adjustment Disorders; Administration, Oral; Clinical Trials as Topic; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Injections, Intravenous; Intestinal Absorption; Placebos; Probenecid; Psychiatric Status Rating Scales; Serotonin; Time Factors | 1974 |
Parkinson disease treated with a suspected dopamine receptor agonist.
Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Piperazines; Placebos; Probenecid; Pyrimidines; Receptors, Cholinergic; Tremor; Trihexyphenidyl | 1974 |
Alterations in cerebrospinal fluid dopamine metabolites following physostigmine infusion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Homovanillic Acid; Humans; Male; Middle Aged; Physostigmine; Probenecid | 1981 |
Control of renal factors in plasma homovanillic acid measurements.
Topics: Adult; Circadian Rhythm; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kidney; Male; Probenecid; Water-Electrolyte Balance | 1998 |
Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters.
Topics: Biomarkers; Computer Simulation; Cross-Over Studies; Drug Interactions; Female; Healthy Volunteers; Homovanillic Acid; Humans; Male; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid | 2021 |
182 other study(ies) available for probenecid and homovanillic acid
| Article | Year |
|---|---|
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells.
Topics: Animals; Blood-Brain Barrier; Cimetidine; Convulsants; Endothelium, Vascular; Enzyme Inhibitors; Homovanillic Acid; Indican; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Rats; Rats, Wistar; Transfection; Tritium; Xenopus laevis | 2003 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger | 2004 |
Effects of drugs on the formation of homovanillic acid in the rat retina.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Rats; Retina | 1976 |
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Intellectual Disability; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias; Probenecid; Seizures; Serotonin; Tyrosine | 1977 |
Brain tyrosine level controls striatal dopamine synthesis in haloperidol-treated rats.
Topics: Animals; Brain Chemistry; Corpus Striatum; Dopamine; Drug Interactions; Haloperidol; Homovanillic Acid; Male; Probenecid; Rats; Tyrosine; Tyrosine 3-Monooxygenase | 1977 |
Neurochemistry of withdrawal emergent symptoms in children.
Topics: Antipsychotic Agents; Child; Child, Preschool; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetates; Probenecid; Time Factors | 1978 |
Cerebral transmitter precursors and metabolites in advanced renal disease.
Topics: Adult; Aged; Brain; Brain Diseases; Fatty Acids, Nonesterified; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurotransmitter Agents; Probenecid; Serum Albumin; Sex Factors; Tryptophan; Tyrosine; Uremia | 1978 |
A syndrome of hypersomnia with automatic behavior.
Topics: Adult; Attention; Automatism; Circadian Rhythm; Electroencephalography; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Narcolepsy; Photic Stimulation; Probenecid; Psychological Tests; Sleep; Sleep Wake Disorders; Syndrome; Visual Perception; Wakefulness | 1975 |
Monoamine accumulation among sclerotic patients receiving dorsal-column stimulation.
Topics: Amyotrophic Lateral Sclerosis; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Multiple Sclerosis; Phenylacetates; Probenecid; Stimulation, Chemical | 1978 |
The concentrations of amine metabolites in cerebrospinal fluid from normal and narcoleptic dogs [proceedings].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dogs; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Narcolepsy; Probenecid | 1979 |
A model of dopamine metabolism in rat brain, assessed by the influence of drugs [proceedings].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Haloperidol; Homovanillic Acid; Pargyline; Probenecid; Rats | 1979 |
[Determination of HVA and 5-HIAA in epileptic syndromes in basal conditions and after treatment with probenecid].
Topics: Adolescent; Adult; Anticonvulsants; Brain; Dopamine; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Probenecid; Serotonin | 1979 |
Encephalopathy associated with bismuth salt ingestion and brain monoamines.
Topics: Adult; Aged; Bismuth; Brain Diseases; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylacetates; Probenecid | 1979 |
Effects of haloperidol and probenecid on plasma and CSF dopamine metabolites in the rhesus monkey (Macacca mulatta).
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Drug Interactions; Haloperidol; Haplorhini; Homovanillic Acid; Macaca mulatta; Male; Probenecid; Starvation; Time Factors | 1978 |
Increased HVA levels in primate ventricular CSF following amphetamine administration.
Topics: Animals; Dextroamphetamine; Haplorhini; Homovanillic Acid; Macaca fascicularis; Phenylacetates; Probenecid | 1979 |
CSF homovanillic acid: an index of dopaminergic activity.
Topics: Antiparkinson Agents; Brain; Dopamine; Hepatic Encephalopathy; Homovanillic Acid; Humans; Huntington Disease; Motor Neurons; Neuromuscular Diseases; Parkinson Disease, Secondary; Phenylacetates; Probenecid | 1975 |
Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Atropine; Brain; Brain Chemistry; Clozapine; Corpus Striatum; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Male; Morphine; Oxotremorine; Phenylacetates; Physostigmine; Pimozide; Probenecid; Rats; Substantia Nigra; Trihexyphenidyl | 1975 |
Levodopa in Huntingtons chorea.
Topics: Adult; Aged; Behavior; Drug Administration Schedule; Electroencephalography; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Levodopa; Long-Term Care; Male; Middle Aged; Probenecid | 1976 |
Intravenous probenecid loading. Effects on plasma and cerebrospinal fluid probenecid levels and on monoamine metabolites in cerebrospinal fluid.
Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Injections, Intravenous; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Time Factors | 1976 |
A menstruation-linked periodic hypersomnia. Kleine-Levin syndrome or new clinical entity?
Topics: Adolescent; Disorders of Excessive Somnolence; Electroencephalography; Estrogens, Conjugated (USP); Feeding and Eating Disorders; Female; Hallucinations; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Luteinizing Hormone; Menstruation; Mental Disorders; Methylphenidate; Periodicity; Probenecid; Progesterone; Psychological Tests; Sleep Stages; Sleep Wake Disorders; Syndrome | 1975 |
Probenecid-induced accumulation of cyclic nucleotides, 5-hydroxyindoleacetic acid, and homovanillic acid in cisternal spinal fluid of genetically nervous dogs.
Topics: Animals; Cisterna Magna; Cyclic AMP; Cyclic GMP; Dogs; Female; Genetics, Behavioral; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nucleotides, Cyclic; Phenylacetates; Probenecid; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Serotonin; Species Specificity; Time Factors | 1976 |
Effects of amphetamine and chlordiazepoxide on probenecid-induced accumulation of acidic metabolites in the cerebrospinal fluid of the dog.
Topics: Amphetamine; Animals; Behavior, Animal; Chlordiazepoxide; Cyclic AMP; Cyclic GMP; Dogs; Female; Genes; Genetics, Behavioral; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Phenylacetates; Probenecid | 1977 |
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: studies in psychiatric patients.
Topics: Adolescent; Adult; Aged; Biogenic Amines; Chlorpromazine; Cyclic AMP; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Probenecid; Schizophrenia | 1979 |
Cerebrospinal fluid homovanillic acid, 5-hydroxyindoleacetic acid, lactic acid, and pH before and after probenecid in hepatic coma.
Topics: Acid-Base Equilibrium; Adult; Aged; Dopamine; Hepatic Encephalopathy; Homovanillic Acid; Humans; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Lactates; Liver; Liver Cirrhosis; Middle Aged; Neurologic Manifestations; Phenylacetates; Probenecid; Serotonin | 1975 |
Assessment of cerebrospinal monoamine metabolites in children using the probenecid method.
Topics: Adolescent; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Phenylacetates; Probenecid | 1977 |
Chronic, multiple tics of Gilles de la Tourette's disease. CSF acid monoamine metabolites after probenecid administration.
Topics: Adolescent; Brain; Child; Dextroamphetamine; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Neural Pathways; Phenylacetates; Probenecid; Serotonin; Tourette Syndrome | 1978 |
Biogenic amine metabolism in Tourette syndrome.
Topics: Biogenic Amines; Child; Child, Preschool; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Probenecid; Serotonin; Tourette Syndrome | 1979 |
Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease.
Topics: 5-Hydroxytryptophan; Aged; Alzheimer Disease; Carbidopa; Dementia; Dopamine; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurocognitive Disorders; Probenecid; Serotonin; Tyrosine | 1977 |
Abnormal central monoamine metabolism in humans with "true hypersomnia" and "sub-wakefulness".
Topics: 3-Methoxy-4-hydroxyphenylethanol; Adolescent; Catechols; Child; Disorders of Excessive Somnolence; Dopamine; Feeding and Eating Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetates; Probenecid; Serotonin; Sleep Wake Disorders; Syndrome | 1977 |
Effect of probenecid on the concentration of the lumbar cerebrospinal fluid acidic metabolites of tyramine, octopamine, dopamine and norepinephrine.
Topics: Dopamine; Female; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Male; Norepinephrine; Octopamine; Probenecid; Schizophrenia; Tyramine | 1977 |
Evidence for a probenecid-sensitive transport system of acid monoamine metabolites from the spinal subarachnoid space.
Topics: Animals; Biogenic Amines; Biological Transport, Active; Cats; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Perfusion; Probenecid; Spinal Cord; Subarachnoid Space; Time Factors | 1977 |
Transient hyperkinesia after a single intravenous perfusion of diphenylhydantoin. Report of a case associated with nontoxic plasma levels of diphenylhydantoin.
Topics: Adolescent; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hyperkinesis; Infusions, Parenteral; Male; Phenytoin; Probenecid | 1979 |
The effect of fasting on the metabolism of 5-hydroxytryptamine and dopamine in the brain of the mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Corpus Striatum; Dopamine; Fasting; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Probenecid; Serotonin | 1979 |
Turnover of free and conjugated (sulphonyloxy) dihydroxyphenylacetic acid and homovanillic acid in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Homovanillic Acid; Kinetics; Male; Pargyline; Phenylacetates; Probenecid; Rats | 1979 |
A simple, sensitive method for measuring 3,4-dihydroxyphenylacetic acid and homovanillic acid in rat brain tissue using high-performance liquid chromatography with electrochemical detection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Phenylacetates; Probenecid; Rats; Tissue Distribution | 1979 |
Changes in striatal dopamine metabolism during precipitated morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzomorphans; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Monoamine Oxidase; Morphine; Naloxone; Probenecid; Rats; Substance Withdrawal Syndrome; Time Factors; Tyramine | 1977 |
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalography; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan | 1977 |
Aspects of influx and efflux of homovanillic acid of rat cerebrospinal fluid.
Topics: Animals; Brain; Cerebral Ventricles; Cisterna Magna; Female; Homovanillic Acid; Male; Pargyline; Perfusion; Phenylacetates; Probenecid; Rats; Spinal Cord; Subarachnoid Space; Tropolone | 1978 |
Biogenic amines in 47, XYY syndrome.
Topics: Adult; Aggression; Central Nervous System; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetates; Probenecid; Serotonin; Sex Chromosome Aberrations; Sleep Stages | 1978 |
Effects of morphine on the turnover of brain catecholamines and serotonin in rats-acute morphine administration.
Topics: 3-Methoxy-4-hydroxyphenylethanol; Animals; Biological Transport, Active; Brain; Catecholamines; Dopamine; Homovanillic Acid; Male; Methyltyrosines; Morphine; Norepinephrine; Probenecid; Rats; Serotonin; Time Factors | 1975 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Phenobarbital; Phenylacetates; Phenytoin; Primidone; Probenecid | 1975 |
Homovanillic acid transport by the spinal cord.
Topics: Animals; Biological Transport; Haplorhini; Homovanillic Acid; Macaca mulatta; Phenylacetates; Probenecid; Spinal Cord; Subarachnoid Space | 1976 |
Homovanillic acid and 3-methoxy-4-hydroxyphenylethyleneglycol production by the monkey spinal cord.
Topics: Animals; Glycols; Haplorhini; Homovanillic Acid; Macaca mulatta; Methoxyhydroxyphenylglycol; Perfusion; Phenylacetates; Probenecid; Spinal Cord | 1976 |
Conjugated 3,4 dihydroxy phenyl acetic acid (DOPAC) in human and monkey cerebrospinal fluid and rat brain and the effects of probenecid treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Transport; Caudate Nucleus; Haplorhini; Homovanillic Acid; Humans; Mass Spectrometry; Phenylacetates; Probenecid; Rats | 1976 |
Progressive effects of cocaine on behavior and central amine metabolism in rhesus monkeys: relationship to kindling and psychosis.
Topics: Animals; Behavior, Animal; Catalepsy; Cocaine; Female; Haplorhini; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Limbic System; Macaca mulatta; Male; Motor Activity; Phenylacetates; Probenecid; Psychoses, Substance-Induced; Seizures; Stereotyped Behavior; Visual Perception | 1976 |
Clinical evidence for neurochemical adaptation to psychotrophic drugs [proceedings].
Topics: Adaptation, Physiological; Biogenic Amines; Homovanillic Acid; Humans; Probenecid; Tranquilizing Agents | 1977 |
Dopamine and serotonin metabolism in neuropsychiatrically disturbed children. CSF homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Adolescent; Age Factors; Aphasia; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Child, Preschool; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Phenylacetates; Probenecid; Psychotic Disorders; Serotonin; Sex Factors | 1977 |
The significance of dopamine for the mode of action of neuroleptics and the pathogenesis of schizophrenia.
Topics: Dopamine; Homovanillic Acid; Humans; Probenecid; Schizophrenia; Tranquilizing Agents | 1977 |
The influence of 3,4-dihydroxyphenylacetic acid on the accumulation of 5-hydroxyindoleacetic acid in the choroid plexus and kidney cortex slices of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antimetabolites; Biological Transport, Active; Calcium; Choroid Plexus; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Kidney Cortex; Magnesium; Phenylacetates; Probenecid; Rats; Time Factors | 1977 |
The effects of morphine on the accumulation of homovanillic and 5-hydroxyindoleacetic acids in the choroid plexus of rats.
Topics: Amino Acids; Animals; Choroid Plexus; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Morphinans; Morphine; Phenylacetates; Probenecid; Rats; Time Factors | 1977 |
The dynamics of dopamine metabolism in various regions of rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; Hippocampus; Homovanillic Acid; Hypothalamus; In Vitro Techniques; Male; Medulla Oblongata; Mesencephalon; Pargyline; Probenecid; Rats | 1977 |
Brain dopamine turnover and the relief of parkinsonism.
Topics: Brain; Bromocriptine; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; Piperazines; Piribedil; Probenecid | 1977 |
Brain dopamine turnover and the relief of parkinsonism.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Bromocriptine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Parkinson Disease; Piperazines; Piribedil; Probenecid; Receptors, Dopamine | 1977 |
Acidic dopamine metabolites in cortical areas of the rat brain: localization and effects of drug.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Morphine; Olfactory Bulb; Oxotremorine; Phenylacetates; Probenecid; Rats; Sulpiride; Thioridazine | 1976 |
Turnover of acid dopamine metabolites in striatal and mesolimbic tissue of the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Limbic System; Male; Pargyline; Probenecid; Rats; Time Factors; Tropolone | 1976 |
Effect of ketamine anaesthesia on the content of monoamines and their metabolites in the rat brain.
Topics: Anesthesia, General; Animals; Brain; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Ketamine; Male; Norepinephrine; Phenylacetates; Probenecid; Rats; Serotonin; Thiopental; Time Factors | 1976 |
Effect of probenecid on endogenous and exogenous 3,4-dihydroxyphenylacetic acid and homovanillic acid in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Depression, Chemical; Dopamine; Female; Hippocampus; Homovanillic Acid; Injections, Intraventricular; Kinetics; Male; Pargyline; Phenylacetates; Probenecid; Rats | 1976 |
14C-homovanillic acid in the cerebrospinal fluid of parkinsonian patients after intravenous 14C-L-dopa.
Topics: Aged; Brain; Carbidopa; Carboxy-Lyases; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Sensory Receptor Cells | 1976 |
CSF acid monoamine metabolities as a possible reflection of central MAO activity in chronic schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Bipolar Disorder; Chronic Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Monoamine Oxidase; Phenylacetates; Probenecid; Schizophrenia | 1976 |
Comparison of effects of drugs on dopamine metabolism in the substantia nigra and the corpus striatum of rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chloral Hydrate; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Promethazine; Rats; Receptors, Dopamine; Substantia Nigra | 1976 |
Baclofen and gamma-hydroxybutyrate: similar effects on cerebral dopamine neurones.
Topics: Aminobutyrates; Animals; Baclofen; Behavior, Animal; Body Temperature; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxybutyrates; Hydroxyindoleacetic Acid; Kinetics; Limbic System; Male; Neurons; Norepinephrine; Probenecid; Rats; Serotonin | 1976 |
[Cerebral metabolism of dopamine and of serotonin during Alzheimer and Pick's diseases. Dynamic study by the test using probenecid].
Topics: Aged; Alzheimer Disease; Brain Chemistry; Dementia; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Serotonin | 1976 |
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cerebral Palsy; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus; Probenecid; Serotonin | 1975 |
Action of cerebral ischemia on decreased levels of 3-methoxy-4-hydroxy-phenylethylgylcol sulfate, homovanillic acid and 5-hydroxy-indoleacetic acid produced by pargyline.
Topics: 3-Methoxy-4-hydroxyphenylethanol; Animals; Brain; Gerbillinae; Glycols; Homovanillic Acid; Hydroxyindoleacetic Acid; Ischemia; Pargyline; Probenecid | 1975 |
Thioridazine: central dopamine turnover and clinical effects of antipsychotic drugs.
Topics: Adolescent; Adult; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Prognosis; Psychiatric Status Rating Scales; Schizophrenia; Thioridazine | 1975 |
Dopamine metabolism in the tuberculum olfactorium.
Topics: Animals; Chromatography, Gas; Corpus Striatum; Dopamine; Homovanillic Acid; Olfactory Bulb; Pargyline; Phenylacetates; Probenecid; Rats | 1975 |
Evaluation of dopamine metabolism in rat striatum by a gas chromatographic technique.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, Gas; Corpus Striatum; Dopamine; Homovanillic Acid; In Vitro Techniques; Male; Methods; Pargyline; Probenecid; Propionates; Rats | 1975 |
Venezuelan equine encephalomyelitis virus infection: effect on monoamine metabolism of mouse brain.
Topics: Animals; Biogenic Amines; Brain; Dopamine; Encephalitis Virus, Venezuelan Equine; Encephalomyelitis, Equine; Homovanillic Acid; Mice; Norepinephrine; Probenecid; Serotonin | 1975 |
Cerebrospinal fluid amine metabolites in acute schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Amines; Bipolar Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Probenecid; Schizophrenia; Serotonin; Spinal Puncture | 1975 |
Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of the specificity of biological variables in behaviour disorders.
Topics: Adjustment Disorders; Bipolar Disorder; Brain; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Motor Activity; Parkinson Disease; Probenecid; Psychomotor Disorders; Psychotic Disorders | 1975 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
The effect of yohimbine on the turnover of brain catecholamines and serotonin.
Topics: Animals; Brain; Catecholamines; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Norepinephrine; Probenecid; Rats; Serotonin; Time Factors; Yohimbine | 1975 |
Probenecid: dosage, levels in plasma and cerebrospinal fluid (CSF) and influence upon CSF levels of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) in the rabbit.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Phenylacetates; Probenecid; Rabbits; Regression Analysis | 1975 |
The effect of probenecid on catecholamine metabolites in human cerebrospinal fluid analyzed by mass fragmentography.
Topics: Brain; Cerebrospinal Fluid; Dopamine; Homovanillic Acid; Humans; Norepinephrine; Phenylacetates; Probenecid; Vanilmandelic Acid | 1975 |
Homovanillic acid and 5-hydroxyindoleacetic acid cerebrospinal fluid levels. A study with and without probenecid administration of their relationship to the state of consciousness after head injury.
Topics: Blood-Brain Barrier; Brain Injuries; Consciousness; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Probenecid; Spinal Puncture; Time Factors | 1975 |
Cerebrospinal fluid amine metabolites in affective illness and schizophrenia: clinical and pharmacological studies.
Topics: Affective Symptoms; Amines; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Probenecid; Schizophrenia | 1975 |
Serotonin (5HT) systems in psychotic states.
Topics: Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Probenecid; Psychotic Disorders; Serotonin; Time Factors | 1975 |
Effects of electrical stimulation of the nigrostriatal pathway of the rat on dopamine metabolism.
Topics: Afferent Pathways; Animals; Apomorphine; Chloral Hydrate; Corpus Striatum; Dopamine; Electric Stimulation; Homovanillic Acid; Isoquinolines; Male; Methyltyrosines; Probenecid; Rats; Substantia Nigra; Tyrosine | 1976 |
CSF amine metabolites in depression.
Topics: Adult; Chromatography, High Pressure Liquid; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probenecid | 1992 |
Anticonvulsant activity of di-n-propylacetate and brain monoamine metabolism in the rat.
Topics: Animals; Biogenic Monoamines; Brain; Catecholamines; Epilepsy; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Pentylenetetrazole; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Valproic Acid | 1990 |
Intercorrelations among monoamine metabolite concentrations in human lumbar CSF are not due to a shared acid transport system.
Topics: Acid-Base Equilibrium; Administration, Oral; Blood-Brain Barrier; Depressive Disorder; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Probenecid; Psychotic Disorders; Schizophrenia | 1990 |
Active transport pumps of HVA and DOPAC in dopaminergic nerve terminals.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Transport, Active; Brain; Cats; Dopamine; Homovanillic Acid; Membrane Potentials; Potassium Chloride; Probenecid; Putamen; Receptors, Dopamine; Synaptic Transmission | 1991 |
3,4-Dihydroxyphenylethylamine and 5-hydroxytryptamine metabolism in the rat: acidic metabolites in cisternal cerebrospinal fluid before and after giving probenecid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1985 |
Repeated determination of cerebrospinal fluid amine metabolites by automated direct sampling from an implanted cannula in freely moving rats.
Topics: alpha-Methyltyrosine; Animals; Biogenic Amines; Catheters, Indwelling; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Methyltyrosines; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Spinal Puncture | 1985 |
Central serotonin agonist actions of LY 165163, 1-(m-trifluoromethylphenyl)-4-(p-aminophenylethyl) piperazine, in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amides; Animals; Brain Chemistry; Corticosterone; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Metergoline; Piperazines; Probenecid; Prolactin; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Effect of probenecid on cerebral and cisternal cerebrospinal fluid lactate content.
Topics: Animals; Brain; Cisterna Magna; Energy Metabolism; Glucose; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypoxia; Lactates; Lactic Acid; Male; Probenecid; Rats; Rats, Inbred Strains | 1987 |
The fall of homovanillic acid and 5-hydroxyindoleacetic acid concentrations in brains of mice withdrawn from repeated morphine treatment and their restoration by acute morphine administration.
Topics: Animals; Body Weight; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Morphine; Morphine Dependence; Probenecid; Serotonin; Substance Withdrawal Syndrome; Telencephalon | 1987 |
[Exploration of the metabolism of brain serotonin and dopamine in prolonged traumatic coma:prognostic value].
Topics: Brain Injuries; Coma; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Probenecid; Serotonin | 1986 |
Determinations of 5-hydroxyindoleacetic acid and homovanillic acid in human CSF with monitoring of probenecid levels in CSF and plasma.
Topics: Adult; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Male; Probenecid | 1987 |
The effect of valproic acid on the 5-hydroxyindoleacetic, homovanillic and lactic acid levels of cerebrospinal fluid.
Topics: Animals; Anticonvulsants; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Lactates; Lactic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Valproic Acid | 1987 |
Probenecid-induced accumulation of 5-hydroxyindoleacetic acid and homovanillic acid in rat brain.
Topics: Animals; Brain Chemistry; Homovanillic Acid; Hydroxyindoleacetic Acid; Infusions, Intravenous; Male; Probenecid; Rats; Rats, Inbred Strains | 1987 |
Intraventricular microdialysis: a new method for determining monoamine metabolite concentrations in the cerebrospinal fluid of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Animals; Cerebral Ventricles; Dialysis; Dopamine; Female; Haloperidol; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Oxidopamine; Phenylacetates; Probenecid; Rats; Substantia Nigra | 1988 |
Tryptophan, 5-HTP, 5-HT and 5-HIAA in the cerebrospinal fluid and sexual behavior in male rats.
Topics: 5-Hydroxytryptophan; Animals; Fenclonine; Homovanillic Acid; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Sexual Behavior, Animal; Tryptophan | 1989 |
Effect of the cerebral tryptaminergic system on the turnover of dopamine in the striatum of the rat.
Topics: 5-Hydroxytryptophan; Animals; Corpus Striatum; Dopamine; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin | 1985 |
CSF monoamine metabolite levels in Alzheimer's and Parkinson's disease.
Topics: Adult; Aged; Alzheimer Disease; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid | 1985 |
Lumbar cerebrospinal fluid homovanillic acid concentrations are higher in female than male non-human primates.
Topics: Animals; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca nemestrina; Male; Phenylacetates; Probenecid; Sex Characteristics | 1985 |
Neurochemistry of dopamine in Huntington's dementia and normal aging.
Topics: Adult; Aged; Aging; Brain; Dementia; Dopamine; Homovanillic Acid; Humans; Huntington Disease; Male; Middle Aged; Probenecid | 1986 |
Chronic cocaine administration decreases dopamine synthesis rate and increases [3H] spiroperidol binding in rat brain.
Topics: Animals; Brain Chemistry; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Injections, Intraperitoneal; Kinetics; Limbic System; Male; Mesencephalon; Probenecid; Rats; Rats, Inbred Strains | 1987 |
Monitoring dopamine metabolism in the brain of the freely moving rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Circadian Rhythm; Dopamine; Homovanillic Acid; Male; Motor Activity; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Stress, Physiological | 1986 |
Effect of various centrally acting drugs on the efflux of dopamine metabolites from the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Biological Transport, Active; Brain; Brain Stem; Central Nervous System Agents; Chloral Hydrate; Chlorpromazine; Corpus Striatum; Dopamine; Frontal Lobe; Haloperidol; Homovanillic Acid; Kainic Acid; Male; Olfactory Bulb; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Rats | 1986 |
Dopaminergic effects of carbamazepine. Relationship to clinical response in affective illness.
Topics: Adult; Animals; Carbamazepine; Depressive Disorder; Dopamine; Female; Homovanillic Acid; Humans; Male; Probenecid; Rats; Receptors, Dopamine | 1986 |
The dynamics of dopamine metabolism in the rat superior cervical, coeliac and mesenteric ganglia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Animals; Dopamine; Ganglia, Sympathetic; Homovanillic Acid; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains | 1985 |
Clinical significance of probenecid test.
Topics: Brain Diseases; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; Phenylacetates; Probenecid | 1973 |
Probenecid test in Parkinson's disease.
Topics: Homovanillic Acid; Humans; Methods; Parkinson Disease; Probenecid | 1971 |
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypoxia; Kinetics; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Probenecid; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1973 |
Norepinephrine metabolism in the central nervous system of man: studies using 3-methoxy-4-hydroxyphenylethylene glycol levels in cerebrospinal fluid.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Carbon Radioisotopes; Cerebrospinal Fluid; Child; Chromatography, Gas; Dihydroxyphenylalanine; Dopamine; Down Syndrome; Dystonia Musculorum Deformans; Female; Glycols; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Middle Aged; Norepinephrine; Parkinson Disease; Picolinic Acids; Probenecid; Serotonin; Spinal Cord Diseases; Time Factors | 1973 |
Central monoamine metabolism in man. Effect of putative dopamine receptor agonists and antagonists.
Topics: Adult; Basal Ganglia Diseases; Brain; Central Nervous System Diseases; Dopamine; Haloperidol; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Muscular Diseases; Parkinson Disease; Piperazines; Probenecid; Receptors, Drug; Serotonin | 1973 |
Proceedings: Turnover of biogenic amines after acute and chronic morphine treatment in rats.
Topics: Acetamides; Animals; Biogenic Amines; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Methyltyrosines; Morphine; Norepinephrine; Probenecid; Rats; Serotonin; Time Factors | 1974 |
Brain serotonin, affective illness, and antidepressant drugs: cerebrospinal fluid studies with probenecid.
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Depression; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Probenecid; Serotonin; Spinal Puncture; Time Factors; Tryptophan | 1974 |
The elimination of 5-hydroxyindoleacetic acid from cerebrospinal fluid: characteristics of the acid transport system of the choroid plexus.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Cephaloridine; Choroid Plexus; Cyclic AMP; Extracellular Space; Glycols; Homovanillic Acid; Hydroxyindoleacetic Acid; Indoles; Inulin; Kinetics; Male; Probenecid; Rats; Time Factors; Vanilmandelic Acid | 1974 |
Adenosine 3',5'-monophosphate in cerebrospinal fluid. Effect of drugs and neurologic disease.
Topics: Adolescent; Adult; Aged; Cerebellar Diseases; Child; Cyclic AMP; Dihydroxyphenylalanine; Female; Homovanillic Acid; Humans; Huntington Disease; Male; Middle Aged; Movement Disorders; Muscular Diseases; Parkinson Disease; Peripheral Nervous System Diseases; Probenecid; Spinal Cord Diseases | 1973 |
Dopaminergic nervous transmission in Parkinson's disease.
Topics: Acetylcholinesterase; Aromatic Amino Acid Decarboxylase Inhibitors; Autopsy; Brain; Brain Chemistry; Dihydroxyphenylalanine; DNA; Dopa Decarboxylase; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Parkinson Disease; Probenecid; RNA; Serotonin; Stimulation, Chemical; Synaptic Transmission; Time Factors | 1974 |
Psychomotor activity, sleep, and biogenic amine metabolites in depression.
Topics: Adult; Biological Transport, Active; Circadian Rhythm; Depression; Electroencephalography; Electromyography; Electrooculography; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Motor Activity; Probenecid; Sleep; Sleep, REM; Telemetry; Time Factors | 1974 |
Serotonin and dopamine turnover after acute and chronic morphine administration.
Topics: Animals; Brain; Brain Chemistry; Dopamine; Drug Tolerance; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Morphine; Morphine Dependence; Probenecid; Rats; Serotonin; Substance Withdrawal Syndrome | 1974 |
Clinical studies of dopaminergic mechanisms.
Topics: Antiparkinson Agents; Dioxoles; Dopamine; Drug Evaluation; Haloperidol; Homovanillic Acid; Humans; Levodopa; Parkinson Disease; Piperidines; Probenecid; Pyrimidines | 1974 |
Accumulation of 3H-homovanillic acid in rabbit brain and cerebrospinal fluid following intravenous 3H-L-dopa.
Topics: Animals; Brain; Brain Chemistry; Carboxy-Lyases; Cerebrospinal Fluid; Chlorpromazine; Chromatography, Thin Layer; Deamination; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Injections, Intravenous; Male; Methylation; Neurons; Phenylacetates; Probenecid; Rabbits; Stimulation, Chemical; Time Factors; Tritium | 1974 |
Biogenic amines in autistic and atypical children. Cerebrospinal fluid measures of homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Autistic Disorder; Brain; Child; Child, Preschool; Diagnosis, Differential; Dopamine; Electroencephalography; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lumbosacral Region; Male; Movement Disorders; Neurologic Examination; Phenylacetates; Probenecid; Psychotic Disorders; Serotonin | 1974 |
Parkinson's disease and amine metabolites in cerebrospinal fluid: implications for L-Dopa therapy.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Depression, Chemical; Dopa Decarboxylase; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Stimulation, Chemical; Time Factors | 1974 |
Homovanillic acid and 5-hydroxyindoleacetic acid in cerebrospinal fluid of a child with familial dysautonomia.
Topics: Child; Dysautonomia, Familial; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Probenecid | 1973 |
Accumulation of 3-methoxy-4-hydroxyphenylglycol-sulfate in rabbit cerebrospinal fluid following probenecid.
Topics: Animals; Brain; Cerebral Cortex; Glycols; Homovanillic Acid; Mesencephalon; Norepinephrine; Phenylacetates; Probenecid; Rabbits | 1973 |
Acid monoamine metabolites in the cerebrospinal fluid of Parkinsonian patients treated with levodopa alone or combined with a decarboxylase inhibitor.
Topics: Adult; Aged; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Libido; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Serotonin | 1973 |
Acid monoamine metabolites in cerebrospinal fluid in multiple sclerosis.
Topics: Acute Disease; Adult; Brain; Chronic Disease; Demyelinating Diseases; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Multiple Sclerosis; Phenylacetates; Probenecid | 1973 |
On the elimination of 5-hydroxyindoleacetic acid and homovanillic acid from cerebrospinal fluid.
Topics: Animals; Benzoates; Benzyl Compounds; Biological Transport, Active; Blood-Brain Barrier; Brain; Brain Stem; Caudate Nucleus; Dogs; Dopamine; Half-Life; Homovanillic Acid; Hydroxyindoleacetic Acid; Norepinephrine; Phenylacetates; Probenecid; Rabbits; Rats; Serotonin; Species Specificity; Sulfonamides; Time Factors; Zoxazolamine | 1973 |
Quantitative determination of homovanillic acid in serum by mass fragmentography.
Topics: Adult; Animals; Chromatography, Gas; Chromatography, Ion Exchange; Deuterium; Female; Goats; Homovanillic Acid; Humans; Male; Mass Spectrometry; Methods; Nialamide; Phenylacetates; Physical Exertion; Probenecid; Time Factors; Tritium | 1973 |
The influence of probenecid on the metabolism of serotonin, dopamine and their precursors in man.
Topics: Adult; Aged; Amino Acids; Brain; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Serotonin; Time Factors; Tryptophan; Tyrosine | 1973 |
Interaction of (+)-amphetamine with cerebral dopaminergic neurones in two strains of mice, that show different temperature responses to this drug.
Topics: Animals; Body Temperature; Brain; Brain Stem; Corpus Striatum; Dextroamphetamine; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Neurons; Norepinephrine; Probenecid; Serotonin | 1973 |
Spontaneous and drug-induced changes of cerebral dopamine turnover during postnatal development of rats.
Topics: Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Feedback; Female; Haloperidol; Homovanillic Acid; Male; Norepinephrine; Phenylacetates; Probenecid; Rats; Receptors, Adrenergic | 1973 |
Effect of ECT on dopaminergic and noradrenergic mechanisms. II. Effect on dopamine and noradrenaline concentrations and turnovers.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Dopamine; Electroconvulsive Therapy; Homovanillic Acid; Male; Methyltyrosines; Norepinephrine; Probenecid; Rats; Time Factors | 1974 |
The effect of probenecid and large dose amphetamine administration on cerebrospinal fluid homovanillic acid.
Topics: Adult; Dextroamphetamine; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Male; Methoxyhydroxyphenylglycol; Phenylacetates; Probenecid; Spinal Puncture | 1974 |
[Disturbances of monoamine metabolism in organic presenile and senile dementia].
Topics: Caudate Nucleus; Corpus Striatum; Dementia; Dopamine; Globus Pallidus; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Probenecid; Stimulation, Chemical | 1974 |
Lumbar CSF 5-hydroxyindoleacetic acid and homovanillic acid in affective syndromes.
Topics: Adult; Affective Symptoms; Amitriptyline; Animals; Bipolar Disorder; Brain Chemistry; Cats; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Phenelzine; Phenylacetates; Probenecid; Rats; Sleep; Spinal Puncture | 1974 |
Central dopamine turnover in schizophrenic syndromes.
Topics: Affective Symptoms; Chlorpromazine; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Schizophrenia; Syndrome; Time Factors; Trifluoperazine | 1974 |
Cerebrospinal fluid pH and monoamine and glucolytic metabolites in Alzheimer's disease.
Topics: Affective Symptoms; Aged; Bicarbonates; Carbon Dioxide; Dementia; Female; Glycolysis; Homovanillic Acid; Humans; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Intelligence; Lactates; Male; Middle Aged; Motor Skills; Parkinson Disease; Phenylacetates; Probenecid; Pyruvates | 1974 |
Derivatization and gas chromatographic determination of some biologically important acids in cerebrospinal fluid.
Topics: Alcohols; Anhydrides; Animals; Body Fluids; Carboxylic Acids; Catechols; Chemical Phenomena; Chemistry; Chromatography, Gas; Computers; Fluorine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Indoles; Mass Spectrometry; Phenols; Phenylacetates; Probenecid; Propionates; Pyrrolidonecarboxylic Acid; Rats; Vanilmandelic Acid | 1974 |
Toward a biochemical classification of depression.
Topics: Antidepressive Agents; Biogenic Amines; Brain; Brain Stem; Depression; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Norepinephrine; Nortriptyline; Probenecid; Receptors, Drug; Serotonin; Sleep Deprivation; Spinal Cord; Suicide; Tryptophan | 1974 |
Diagnosis of manic-depressive psychosis from cerebrospinal fluid concentration of 5-hydroxyindoleacetic acid.
Topics: Bipolar Disorder; Dose-Response Relationship, Drug; Half-Life; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Mathematics; Probenecid; Spinal Puncture | 1974 |
Thyroxine and brain catecholamines: increased transmitter synthesis and increased receptor sensitivity.
Topics: Animals; Brain; Clonidine; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Exploratory Behavior; Female; Heart; Homovanillic Acid; Locomotion; Male; Mice; Norepinephrine; Organ Size; Probenecid; Receptors, Adrenergic; Reserpine; Stimulation, Chemical; Thyroxine; Tritium; Tyrosine | 1974 |
Fusaric acid in Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Dihydroxyphenylalanine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Disease; Picolinic Acids; Probenecid | 1974 |
[The probenecid test and its application to research in schizophrenia].
Topics: Biogenic Amines; Brain; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Probenecid; Schizophrenia | 1984 |
[Changes in the CSF levels of monoamine metabolites in 102 chronic schizophrenic patients following probenecid before and after neuroleptic medication].
Topics: Adult; Antipsychotic Agents; Biogenic Amines; Chronic Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Probenecid; Schizophrenia | 1984 |
Clinical processes and central dopaminergic activity in psychotic disorders.
Topics: Adolescent; Adult; Antipsychotic Agents; Dopamine; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Male; Middle Aged; Probenecid; Prolactin; Psychotic Disorders | 1980 |
[Changes in ventricular dopamine and homovanillic acid concentrations in hydrocephalic patients (author's transl)].
Topics: Dopamine; Homovanillic Acid; Humans; Hydrocephalus; Phenylacetates; Probenecid | 1980 |
Dopamine and mania: behavioral and biochemical effects of the dopamine receptor blocker pimozide.
Topics: Adult; Behavior; Bipolar Disorder; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Pimozide; Probenecid; Receptors, Dopamine; Serotonin; Time Factors | 1980 |
CSF monoamine metabolites in child and adult psychiatric patients. A developmental perspective.
Topics: Adolescent; Adult; Age Factors; Aged; Autistic Disorder; Bipolar Disorder; Child; Child, Preschool; Cognition Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Perceptual Disorders; Phenylacetates; Probenecid; Schizophrenia | 1980 |
Estimation of monoamine and cyclic-AMP turnover and amino acid concentrations of spinal fluid in autistic children.
Topics: Amines; Amino Acids; Autistic Disorder; Child; Cyclic AMP; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Probenecid; Serotonin | 1980 |
Ontogeny of dopamine and serotonin metabolites in the cerebrospinal fluid of children with neurological disorders.
Topics: Adolescent; Child; Child, Preschool; Dopamine; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Nervous System Diseases; Phenylacetates; Probenecid; Serotonin | 1980 |
Serotoninergic dysfunction in the 47, XYY syndrome.
Topics: 5-Hydroxytryptophan; Adult; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Serotonin; Sex Chromosome Aberrations; XYY Karyotype | 1980 |
Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with progressive myoclonus epilepsy.
Topics: Adult; Brain; Epilepsies, Myoclonic; Female; Finland; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylacetates; Probenecid; Serotonin | 1980 |
Relationship between estimated premorbid adjustment and CSF homovanillic acid and 5-hydroxyindoleacetic acid levels.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Phenylacetates; Probenecid; Psychotic Disorders; Schizophrenia; Sexual Behavior; Social Adjustment | 1981 |
Biogenic amine disturbances in cerebrospinal fluid in parkinsonism and unipolar depression: use of the probenecid method.
Topics: Aged; Dementia; Depressive Disorder; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Serotonin | 1981 |
Clinical application of the probenecid test for measurement of monoamine turnover in the CNS.
Topics: Brain; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Neurotransmitter Agents; Probenecid; Serotonin | 1981 |
Selective increase in brain dopamine metabolism during REM sleep rebound in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Probenecid; Rats; Rats, Inbred Strains; Sleep Deprivation; Sleep, REM | 1981 |
Neuroendocrine and neurochemical measurements in depression.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Dexamethasone; Glycols; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Phenylacetates; Probenecid; Psychiatric Status Rating Scales; Thyrotropin; Thyrotropin-Releasing Hormone | 1981 |
Serotonin and dopamine disturbances in patients with unipolar depression and Parkinsonism.
Topics: Brain; Depressive Disorder; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Parkinson Disease; Phenylacetates; Probenecid; Serotonin | 1981 |
Measurement of metabolites of dopamine and 5-hydroxytryptamine in cerebroventricular perfusates of unanesthetized, freely-moving rats: selective effects of drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood-Brain Barrier; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Pargyline; Perfusion; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1982 |
Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease.
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; Phenylacetates; Probenecid; Tyrosine | 1982 |
Monoamine metabolite concentrations in the cerebrospinal fluid of normal and narcoleptic dogs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Dogs; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Narcolepsy; Norepinephrine; Probenecid; Serotonin | 1982 |
Decrease of GABA in the cerebrospinal fluid of patients with progressive myoclonus epilepsy and its correlation with the decrease of 5HIAA and HVA.
Topics: Adult; Epilepsies, Myoclonic; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylacetates; Probenecid | 1982 |
Acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders.
Topics: Adjustment Disorders; Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Probenecid; Protein Precursors; Psychomotor Agitation; Psychotic Disorders; Serotonin; Tryptophan; Tyrosine | 1983 |
Probenecid sensitive pathway of elimination of dopamine and serotonin metabolites in CSF of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin | 1983 |
The effects of amfonelic acid on 5-HT metabolism in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Nalidixic Acid; Naphthyridines; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1983 |
Analysis of neurotransmitter metabolites and adenosine 3',5'-monophosphate in the CSF of patients with extrapyramidal motor disorders.
Topics: Adult; Basal Ganglia Diseases; Cyclic AMP; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Male; Parkinson Disease; Phenylacetates; Probenecid; Syndrome | 1984 |
Liquid chromatographic determination of homovanillic acid, 5-hydroxyindoleacetic acid and probenecid levels in human cerebrospinal fluid during probenecid test.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Electrochemistry; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Nervous System Diseases; Phenylacetates; Probenecid; Spectrophotometry, Ultraviolet | 1984 |
Concurrent determination of brain dopamine and 5-hydroxytryptamine turnovers in individual freely moving rats using repeated sampling of cerebrospinal fluid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyldopa; Probenecid; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Determination of daily variations of brain 5-hydroxytryptamine and dopamine turnovers and of the clearance of their acidic metabolites in conscious rats by repeated sampling of cerebrospinal fluid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Circadian Rhythm; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Effect of alpha-methyl fluorodopa on dopamine metabolites: importance of conjugation and egress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyldopa; Probenecid; Rats; Rats, Inbred Strains | 1984 |
Simultaneous determination of norepinephrine, dopamine, 5-hydroxytryptamine and their main metabolites in rat brain using high-performance liquid chromatography with electrochemical detection. Enzymatic hydrolysis of metabolites prior to chromatography.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Acid; Hydrolysis; Hydroxyindoleacetic Acid; Hypothalamus, Middle; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Sulfatases | 1984 |
Differences in brain serotonergic metabolism between nonbulimic and bulimic patients with anorexia nervosa.
Topics: Anorexia Nervosa; Appetite; Body Weight; Brain; Brain Chemistry; Dopamine; Feeding and Eating Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hyperphagia; Probenecid; Serotonin | 1984 |
Decreased brain dopamine synthesis rate and increased [3H]spiroperidol binding in streptozotocin-diabetic rats.
Topics: Animals; Brain; Butyrophenones; Diabetes Mellitus, Experimental; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Insulin; Kinetics; Probenecid; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1983 |
Homovanilic acid in Huntington's disease and Sydenham's chorea.
Topics: Adult; Chorea; Female; Homovanillic Acid; Humans; Huntington Disease; Male; Middle Aged; Phenylacetates; Probenecid | 1981 |
CSF GABA in psychotic disorders.
Topics: Adolescent; Adult; Female; gamma-Aminobutyric Acid; Haloperidol; Homovanillic Acid; Humans; Male; Middle Aged; Probenecid; Psychotic Disorders | 1980 |
Homovanillic acid in the cerebrospinal fluid of Parkinsonian patients.
Topics: Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid | 1983 |
Sleepiness in nonnarcoleptic, non-sleep apneic EDS patients: the idiopathic CNS hypersomnolence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Arousal; Disorders of Excessive Somnolence; Electroencephalography; Female; Homovanillic Acid; Humans; Male; Middle Aged; Probenecid; Reaction Time; Sleep; Sleep Stages; Sleep Wake Disorders | 1982 |
CSF monoamine metabolites in depression and schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Probenecid; Schizophrenia | 1980 |
Subcellular distribution of dopamine metabolites and their elimination from the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Male; Pargyline; Probenecid; Rats; Subcellular Fractions; Tropolone | 1980 |
Effect of ageing on monoamine turnover in the prefrontal cortex of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Prefrontal Cortex; Probenecid; Rats; Rats, Wistar; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
Effect of probenecid and its congeners on brain organic acid transport in rats.
Topics: Acids; Animals; Brain Chemistry; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Wistar; Structure-Activity Relationship | 1993 |
Amantadine enhances dopamine and serotonin turnover in the MPTP model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amantadine; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Parkinson Disease, Secondary; Probenecid; Serotonin | 1993 |
Quinolinic acid is extruded from the brain by a probenecid-sensitive carrier system: a quantitative analysis.
Topics: Animals; Brain; Carrier Proteins; Computer Simulation; Corpus Striatum; Extracellular Space; Female; Gerbillinae; Homovanillic Acid; Models, Biological; Osmolar Concentration; Probenecid; Quinolinic Acid | 1999 |
Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport, Active; Dopamine; Glipizide; Glyburide; Homovanillic Acid; Male; Mice; Microdialysis; Multidrug Resistance-Associated Proteins; PC12 Cells; Potassium Channels; Potassium Channels, Inwardly Rectifying; Probenecid; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Drug; Rhodamines; RNA, Messenger; Sulfonylurea Receptors; Transfection | 2000 |
Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys.
Topics: Animals; Biological Transport; Biomarkers; Cell Line; HEK293 Cells; Homovanillic Acid; Humans; Macaca fascicularis; Metabolomics; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid | 2018 |
Characterization of Elimination Pathways and the Feasibility of Endogenous Metabolites as Biomarkers of Organic Anion Transporter 1/3 Inhibition in Cynomolgus Monkeys.
Topics: Animals; Biomarkers; Drug Interactions; Feasibility Studies; Homovanillic Acid; Humans; Kidney; Kynurenic Acid; Macaca fascicularis; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid | 2023 |