probenecid has been researched along with folic acid in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.89) | 18.7374 |
| 1990's | 12 (33.33) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 7 (19.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Graves, P; Kuze, K; Leahy, A; Stuhlmann, H; Wilson, P; You, G | 1 |
| Hashimoto, Y; Ibaramoto, K; Inui, KI; Masuda, S; Saito, H; Takeuchi, A | 1 |
| Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H | 1 |
| Chen, ZS; Kruh, GD; Kuwano, M; Lee, K; Raftogianis, RB; Walther, S; Zeng, H | 1 |
| Hummel-Eisenbeiss, J; Jedlitschky, G; Keppler, D; Nies, AT; Rius, M | 1 |
| Belinsky, MG; Chen, ZS; Guo, Y; Kotova, E; Kruh, GD | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Huang, KC; Liu, YK; Wenczak, BA | 1 |
| Chen, CP; Wagner, C | 1 |
| Henderson, GB; Tsuji, JM | 1 |
| Besseghir, K; Mosig, D; Roch-Ramel, F | 1 |
| Christensen, ML; Evans, WE | 1 |
| Cohen, AR; Colman, N; Herbert, V; Poncz, M; Schwartz, E | 1 |
| Antony, AC; Henderson, GI; Mackins, J; Perez, T; Schenker, S | 1 |
| Brigle, KE; Goldman, ID; Sierra, EE; Spinella, MJ | 1 |
| Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD | 1 |
| McCloud, E; Mohammadkhani, R; Said, HM | 1 |
| McMartin, KE; Muldoon, RT; Ross, DM | 1 |
| Ma, TY; Ortiz, A; Said, HM; Tapia, A; Valerio, CK | 1 |
| Bagnoli, M; Canevari, S; Colnaghi, MI; Miotti, S; Ottone, F; Tomassetti, A | 1 |
| McMartin, KE; Sikka, PK | 1 |
| Hashimoto, Y; Inui, K; Okuda, M; Takami, K; Uwai, Y | 1 |
| Cai, S; Horne, DW | 1 |
| Kokwaro, G; Marsh, K; Nzila, AM; Ward, SA; Winstanley, PA | 1 |
| Itoh, T; Narawa, T; Tsuda, Y | 1 |
| Hyde, JE; Sims, PF; Wang, P; Wang, Q | 1 |
| Bridges, CC; Campos, I; Costa, F; Gonçalves, P; Keating, E; Lemos, C; Martel, F; Smith, SB | 1 |
| Campanella, E; Goldman, ID; Low, PS; Min, SH; Wang, Y; Zhao, R | 1 |
| Beveridge, S; Biagini, GA; Bray, PG; Johnson, D; Krishna, S; Nzila, A; O'Neill, PM; Ochong, E; Salcedo-Sora, JE; Stocks, PA; Ward, SA | 1 |
| Li, X; Lu, Y; Yin, Z; Yu, Y; Zhao, X | 1 |
3 review(s) available for probenecid and folic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug interactions with methotrexate.
Topics: Absorption; Anti-Bacterial Agents; Arthritis, Rheumatoid; Aspirin; Biological Transport; Cell Membrane; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Folic Acid; Humans; Kidney Tubules; Methotrexate; Probenecid; Protein Binding; Salicylates; Serum Albumin; Sulfamethoxazole; Sulfonamides; Tissue Distribution | 1985 |
Therapeutic potential of folate uptake inhibition in Plasmodium falciparum.
Topics: Animals; Antimalarials; Drug Combinations; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Folic Acid; Folic Acid Antagonists; Malaria, Falciparum; Plasmodium falciparum; Probenecid; Pyrimethamine; Sulfadoxine | 2004 |
33 other study(ies) available for probenecid and folic acid
| Article | Year |
|---|---|
Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells.
Topics: Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; COS Cells; Glycosylation; Histidine; In Situ Hybridization; Kidney; Kinetics; Mice; p-Aminohippuric Acid; Probenecid; Protein Processing, Post-Translational; Renal Agents; Substrate Specificity; Tunicamycin | 1999 |
Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Kidney; Male; Membrane Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Oocytes; Organic Anion Transporters; Rats; Rats, Wistar; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Tissue Distribution; Transfection; Xenopus laevis | 1999 |
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.
Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium | 2001 |
Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.
Topics: Animals; Antimetabolites, Antineoplastic; Baculoviridae; Carrier Proteins; Cell Line; Folate Receptors, GPI-Anchored; Folic Acid; Insecta; Liposomes; LLC-PK1 Cells; Methotrexate; Multidrug Resistance-Associated Proteins; Osmosis; Polyglutamic Acid; Receptors, Cell Surface; Swine; Transfection | 2002 |
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Polarity; Cholagogues and Choleretics; Cricetinae; Fibroblasts; Gene Expression; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Rats; Taurocholic Acid; Transfection; Transport Vesicles; Tritium | 2003 |
Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).
Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Dose-Response Relationship, Drug; Estradiol; Humans; Leukotriene C4; LLC-PK1 Cells; Protein Transport; Swine | 2005 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Renal tubular transport of methotrexate in the rhesus monkey and dog.
Topics: Animals; Biological Transport, Active; Dogs; Female; Folic Acid; Haplorhini; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Macaca mulatta; Methotrexate; Probenecid; Protein Binding; Species Specificity | 1979 |
Folate transport in the choroid plexus.
Topics: Animals; Biological Transport; Choroid Plexus; Dinitrophenols; Folic Acid; In Vitro Techniques; Kinetics; Oxygen; Phenobarbital; Phenytoin; Probenecid; Sodium; Swine; Tetrahydrofolates | 1975 |
Identification of cholate as a shared substrate for the unidirectional efflux systems for methotrexate in L1210 mouse cells.
Topics: Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cholic Acids; Cytochalasin B; Folic Acid; Glucose; Leukemia L1210; Methotrexate; Mice; Probenecid; Substrate Specificity; Sulfobromophthalein; Temperature; Tumor Cells, Cultured; Uric Acid; Vincristine | 1990 |
Transport of methotrexate by the in vitro isolated rabbit proximal tubule.
Topics: Absorption; Animals; Biological Transport; Female; Folic Acid; In Vitro Techniques; Kidney Tubules, Proximal; Male; Methotrexate; Perfusion; Probenecid; Rabbits | 1989 |
Therapy of congenital folate malabsorption.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Injections, Intramuscular; Intestinal Absorption; Leucovorin; Malabsorption Syndromes; Probenecid | 1981 |
Maternal-to-fetal transfer of 5-methyltetrahydrofolate by the perfused human placental cotyledon: evidence for a concentrative role by placental folate receptors in fetal folate delivery.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Carrier Proteins; Ethanol; Female; Fetus; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Probenecid; Receptors, Cell Surface; Tetrahydrofolates; Time Factors | 1995 |
Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells.
Topics: Alkenes; Animals; Biological Transport; Carrier Proteins; Energy Metabolism; Folate Receptors, GPI-Anchored; Folic Acid; Hydrogen-Ion Concentration; Ions; Leukemia L1210; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Polyenes; Probenecid; Pyrones; Receptors, Cell Surface; Reduced Folate Carrier Protein; Sulfobromophthalein; Temperature; Transfection; Tumor Cells, Cultured | 1995 |
Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells.
Topics: Anti-Bacterial Agents; Base Sequence; Carrier Proteins; Choriocarcinoma; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Macrolides; Molecular Sequence Data; Pregnancy; Probenecid; Proton Pumps; Receptors, Cell Surface; Tetrahydrofolates; Tumor Cells, Cultured; Uterine Neoplasms | 1994 |
Mechanism of transport of riboflavin in rabbit intestinal brush border membrane vesicles.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Folic Acid; Furosemide; Ileum; Intestinal Mucosa; Jejunum; Kinetics; Membrane Potentials; Methotrexate; Microvilli; Organ Specificity; Osmolar Concentration; Potassium; Probenecid; Rabbits; Riboflavin; Valinomycin | 1993 |
Folate transport pathways regulate urinary excretion of 5-methyltetrahydrofolate in isolated perfused rat kidney.
Topics: Analysis of Variance; Animals; Biological Transport; Chromatography, High Pressure Liquid; Folic Acid; Kidney; Kidney Tubules, Proximal; Male; Models, Biological; Perfusion; Probenecid; Rats; Rats, Sprague-Dawley; Tetrahydrofolates | 1996 |
Intracellular regulation of intestinal folate uptake: studies with cultured IEC-6 epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cell Line; Folic Acid; Intestinal Mucosa; Intracellular Membranes; Osmolar Concentration; Probenecid; Protein Kinases; Rats | 1997 |
Simultaneous activity of two different mechanisms of folate transport in ovarian carcinoma cell lines.
Topics: Biological Transport; Carrier Proteins; Cell Membrane; Cytosol; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Ovarian Neoplasms; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Probenecid; Receptors, Cell Surface; Tetrahydrofolates; Tumor Cells, Cultured; Type C Phospholipases; Uricosuric Agents | 1997 |
Determination of folate transport pathways in cultured rat proximal tubule cells.
Topics: Animals; Anion Transport Proteins; Aspirin; Biological Transport; Carrier Proteins; Cells, Cultured; Folate Receptors, GPI-Anchored; Folic Acid; Glomerular Filtration Rate; Indomethacin; Kidney Tubules, Proximal; Male; Membrane Proteins; Membrane Transport Proteins; Probenecid; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Reduced Folate Carrier Protein; Renal Agents; Tetrahydrofolates | 1998 |
Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney.
Topics: Animals; Anion Transport Proteins; Anions; Biological Transport; Carrier Proteins; Cell Membrane; Dicarboxylic Acids; Diterpenes; DNA Primers; DNA, Complementary; Female; Folic Acid; Glutarates; Kidney; Kinetics; Methotrexate; Oocytes; p-Aminohippuric Acid; Phorbol Esters; Probenecid; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis | 1998 |
Transport of 5-formyltetrahydrofolate into primary cultured rat astrocytes.
Topics: 4-Chloromercuribenzenesulfonate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Arsenates; Astrocytes; Biological Transport; Buffers; Cells, Cultured; Enzyme Inhibitors; Ethanol; Folic Acid; Hydrogen-Ion Concentration; Leucovorin; Methotrexate; Probenecid; Rats; Rats, Sprague-Dawley; Sodium Cyanide; Tetrahydrofolates | 2003 |
Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Algorithms; Caco-2 Cells; Chromatography, Liquid; Folic Acid; Folic Acid Antagonists; Humans; Mass Spectrometry; Methotrexate; Probenecid; Proteins; Reduced Folate Carrier Protein; Stereoisomerism; Uricosuric Agents | 2007 |
Characterisation of exogenous folate transport in Plasmodium falciparum.
Topics: Animals; Carbohydrate Metabolism; Cell Cycle; Coenzymes; Dinitrophenols; Energy Metabolism; Enzyme Inhibitors; Erythrocytes; Folic Acid; Furosemide; Glycolysis; Humans; Hydrogen-Ion Concentration; Macrolides; Metals; Nigericin; Plasmodium falciparum; Probenecid; Temperature; Uncoupling Agents | 2007 |
Progesterone inhibits folic acid transport in human trophoblasts.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; ATP-Binding Cassette Transporters; Estradiol; Folic Acid; Humans; Indoles; Indomethacin; Kinetics; p-Aminohippuric Acid; Probenecid; Progesterone; Trophoblasts; Verapamil | 2007 |
A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis.
Topics: Biological Transport, Active; Carrier Proteins; Cytosol; Endocytosis; Endosomes; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Malabsorption Syndromes; Membrane Transport Proteins; Metabolism, Inborn Errors; Probenecid; Proton-Coupled Folate Transporter; Receptors, Cell Surface; Uricosuric Agents | 2009 |
The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters.
Topics: Biological Transport, Active; Escherichia coli; Folic Acid; Folic Acid Antagonists; Folic Acid Transporters; Humans; Methotrexate; Plasmodium falciparum; Probenecid; Protozoan Proteins; Uricosuric Agents | 2011 |
Intestinal absorption of raltitrexed and evaluation of the effects of absorption enhancers.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acrylic Resins; Algorithms; Animals; Antimetabolites, Antineoplastic; ATP-Binding Cassette Transporters; Biological Availability; Caco-2 Cells; Decanoic Acids; Deoxycholic Acid; Excipients; Folic Acid; Humans; Intestinal Absorption; Male; Pantoprazole; Probenecid; Quinazolines; Rats; Rats, Wistar; Thiophenes; Verapamil | 2013 |