Page last updated: 2024-08-16

probenecid and digitoxin

probenecid has been researched along with digitoxin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Damm, KH; Erttmann, R2
Braun, W; Damm, KH1
Cacini, W; Wernke, MJ1
Beeck, R; Braun, W; Damm, KH; Erttmann, R; Gerhardt, T1
Braun, W; Damm, KH; Heckert, H1
Damm, KH; Woermann, C1
Kupferberg, HJ; Schankl, LS1

Other Studies

13 other study(ies) available for probenecid and digitoxin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Interaction of probenecid with digitoxin metabolism in rats.
    Toxicology and applied pharmacology, 1975, Volume: 33, Issue:2

    Topics: Animals; Bile; Chromatography, Gel; Chromatography, Thin Layer; Digitoxigenin; Digitoxin; Drug Interactions; Glycosides; In Vitro Techniques; Liver; Male; Probenecid; Rats

1975
Drug interactions in intestinal absorption of 3H-digitoxin in rats.
    Experientia, 1976, May-15, Volume: 32, Issue:5

    Topics: Animals; Digitoxin; Ethacrynic Acid; Intestinal Absorption; Intestine, Small; Kidney; Liver; Male; Mersalyl; Muscles; Organomercury Compounds; Probenecid; Rats

1976
Concentrative uptake of digoxin by slices of chicken renal cortex.
    Biochemical pharmacology, 1990, Feb-15, Volume: 39, Issue:4

    Topics: Animals; Chickens; Digitoxin; Digoxigenin; Digoxin; Female; Hexoses; Kidney Cortex; Kinetics; Ouabain; Potassium; Probenecid; Quinine; Sodium Cyanide; Spironolactone

1990
[The effect of some drugs on the protein binding of phenol red and digitoxin].
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 275, Issue:3

    Topics: Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry, Physical; Dialysis; Digitoxin; Drug Interactions; Phenolphthaleins; Phenylbutazone; Probenecid; Protein Binding; Salicylates; Serum Albumin, Bovine; Tritium

1972
[The effect of probenecid on the distribution of digitoxin, digoxin and ouabain in the mouse].
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 277, Issue:3

    Topics: Animals; Chromatography, Thin Layer; Digitoxin; Digoxin; Heart; Liver; Mice; Muscles; Myocardium; Ouabain; Probenecid; Tritium

1973
The effect of probenecid on the in vitro absorption of cardiac glycosides.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Animals; Biological Transport; Body Water; Calcium; Cardiac Glycosides; Chromatography, Thin Layer; Digitoxin; Digoxin; Ethacrynic Acid; Furosemide; Glucose; Hydrochlorothiazide; In Vitro Techniques; Intestinal Absorption; Jejunum; Mersalyl; Mice; Mice, Inbred Strains; Osmolar Concentration; Ouabain; Oxygen Consumption; Potassium; Probenecid; Sodium; Tritium

1974
Probenecid and hepatic transport of 3-H-ouabain in rats.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 211, Issue:2

    Topics: Alkadienes; Animals; Benzoxazoles; Coloring Agents; Cresols; Depression, Chemical; Digitoxin; In Vitro Techniques; Kinetics; Liver; Male; Ouabain; Probenecid; Rats; Temperature

1974
Biliary secretion of ouabain-3H and its uptake by liver slices in the rat.
    The American journal of physiology, 1968, Volume: 214, Issue:5

    Topics: Aminohippuric Acids; Animals; Bile; Biological Transport, Active; Chromatography, Thin Layer; Digitoxin; Digoxin; Glycosides; Injections, Intravenous; Liver; Liver Extracts; Male; Organ Size; Ouabain; Parasympatholytics; Plants, Medicinal; Probenecid; Procainamide; Rats; Tritium

1968