Page last updated: 2024-08-16

probenecid and daunorubicin

probenecid has been researched along with daunorubicin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (33.33)18.2507
2000's8 (44.44)29.6817
2010's3 (16.67)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Broxterman, HJ; Feller, N; Pinedo, HM; Währer, DC1
Bagrij, T; Twentyman, PR; Versantvoort, CH; Wright, KA1
Fujita, T; Fukuzumi, M; Muranishi, S; Nishimaki, A; Yamada, H; Yamamoto, A1
Berger, W; Elbling, L; Hauptmann, E; Kokoschka, EM; Micksche, M; Vetterlein, M1
Gollapudi, S; Gupta, S; Kim, CH; Sangha, S; Tran, BN1
Aszalos, A; Weaver, JL1
Anagnostopoulos, N; Androutsos, G; Galanopoulos, A; Kalmantis, T; Meletis, J; Paterakis, G; Rombos, Y; Sagriotis, A; Symeonidis, A; Tiniakou, M; Tsimberidou, AM; Yataganas, X; Zoumbos, N1
Leader, JP; O'Donnell, MJ1
Hu, X; Lu, Q; Pan, Q; Sun, M; Xu, X1
Imasaka, T; Kaneta, T; Mbuna, J1

Reviews

2 review(s) available for probenecid and daunorubicin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for probenecid and daunorubicin

ArticleYear
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells.
    Pharmaceutical research, 2001, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): no inhibition by intracellular glutathione depletion.
    FEBS letters, 1995, Jul-17, Volume: 368, Issue:2

    Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport, Active; Buthionine Sulfoximine; Cytoplasm; Daunorubicin; Fluoresceins; Glutathione; Humans; Indicators and Reagents; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; Tumor Cells, Cultured

1995
On the relationship between the probenecid-sensitive transport of daunorubicin or calcein and the glutathione status of cells overexpressing the multidrug resistance-associated protein (MRP).
    International journal of cancer, 1995, Dec-11, Volume: 63, Issue:6

    Topics: Antimetabolites, Antineoplastic; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Daunorubicin; Fluoresceins; Glutathione; Humans; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Probenecid; Tumor Cells, Cultured

1995
Calcein is excreted from the intestinal mucosal cell membrane by the active transport system.
    Life sciences, 1997, Volume: 60, Issue:4-5

    Topics: Animals; Azides; Biological Transport, Active; Caco-2 Cells; Calcium Channel Blockers; Cell Membrane; Cell Membrane Permeability; Daunorubicin; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; In Vitro Techniques; Intestinal Mucosa; Jejunum; Probenecid; Rats; Renal Agents; Sodium Azide; Sodium Fluoride; Verapamil

1997
Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells.
    International journal of cancer, 1997, Mar-28, Volume: 71, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP-Binding Cassette Transporters; Benzbromarone; Blotting, Northern; Cisplatin; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Ethylmaleimide; Etoposide; Female; Fluoresceins; Humans; Male; Melanoma; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; RNA, Messenger; Tumor Cells, Cultured; Uricosuric Agents; Vinblastine

1997
Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; HL-60 Cells; Humans; Leukemia P388; Mice; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; Vincristine

1997
Estimation of drug resistance by flow cytometry.
    Methods in molecular biology (Clifton, N.J.), 1998, Volume: 91

    Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Genistein; Leukemia L5178; Mice; Probenecid; Recombinant Proteins; Rhodamine 123; Rhodamines; Transfection; Tumor Cells, Cultured; Verapamil

1998
Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.
    Leukemia research, 2002, Volume: 26, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Transplantation; Calcium Channel Blockers; Carbocyanines; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Fluoresceins; Fluorescent Dyes; Genistein; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; Prognosis; Prospective Studies; Rhodamine 123; Survival Analysis; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Verapamil

2002
Transepithelial transport of fluorescent p-glycoprotein and MRP2 substrates by insect Malpighian tubules: confocal microscopic analysis of secreted fluid droplets.
    The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 23

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Drosophila melanogaster; Epithelium; Fluorescent Dyes; Gryllidae; Malpighian Tubules; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Probenecid; Propionates; Quinacrine; Quinolines; Tetraethylammonium; Verapamil

2005
Schisandrin B: a dual inhibitor of P-glycoprotein and multidrug resistance-associated protein 1.
    Cancer letters, 2007, Feb-08, Volume: 246, Issue:1-2

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclooctanes; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Lignans; Molecular Structure; Multidrug Resistance-Associated Proteins; Polycyclic Compounds; Probenecid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2007
Micellar electrokinetic chromatographic analysis for in vitro accumulation of anthracyclines enhanced by inhibitors of cell membrane transporter-proteins in cancer cells.
    Biomedical chromatography : BMC, 2011, Volume: 25, Issue:10

    Topics: Biological Transport, Active; Cell Line, Tumor; Cellular Structures; Chromatography, Micellar Electrokinetic Capillary; Cyclosporine; Daunorubicin; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Probenecid; Verapamil

2011