Page last updated: 2024-08-16

probenecid and cyclosporine

probenecid has been researched along with cyclosporine in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (13.21)	18.2507
2000's	25 (47.17)	29.6817
2010's	20 (37.74)	24.3611
2020's	1 (1.89)	2.80

Authors

Authors	Studies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL	1
Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H	1
Hong, J; Lambert, JD; Lee, SH; Sinko, PJ; Yang, CS	1
Honda, Y; Koyabu, N; Kuwano, M; Morimoto, S; Ohtani, H; Sawada, Y; Shoyama, Y; Uchiumi, T; Ushigome, F	1
Horikawa, M; Kato, Y; Sugiyama, Y; Tyson, CA	1
Chang, TK; Ensom, MH; Kiang, TK	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Fent, K; Popovic, M; Smital, T; Zaja, R	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Stein, GE	1
Estepa, MR; Gallego, N; Gámez, C; Marcén, R; Orofino, L; Ortuño, J; Sabater, J; Teruel, JL	1
Grenda, R; Januszewicz, P; Zawadzki, J	1
Arancia, G; Calcabrini, A; Cianfriglia, M; Del Bufalo, D; Meschini, S; Molinari, A; Stringaro, A	1
Aszalos, A; Weaver, JL	1
Bergmann, R; Center, MS; Couraud, PO; El Hafny, B; Koman, A; Piciotti, M; Regina, A; Roux, F	1
Pritchard, JB; Sweet, DH	1
Chakrabarti, S; Collingham, KE; Fegan, CD; Milligan, DW; Osman, H	1
Crowe, A	1
Buesen, R; Jacob, J; Lampen, A; Mock, M; Nau, H; Seidel, A	1
Chanteux, H; Michot, JM; Mingeot-Leclercq, MP; Seral, C; Tulkens, PM; Van Bambeke, F	1
Lim, BG; Ng, KH; Wong, KP	1
Beyer, TD; Dumitriu, IE; Gaipl, US; Herrmann, M; Kalden, JR; Roedel, F	1
Crowe, A; Wong, P	1
Asakura, E; Baba, K; Hasegawa, T; Kitaichi, K; Nadai, M; Sugie, M; Takagi, K; Torita, S; Zhao, YL	1
Tsai, PL; Tsai, TH	1
Dogan, AL; Faussat, AM; Legrand, O; Marie, JP; Perrot, JY	1
Eguchi, K; Ejima, E; Ida, H; Kawakami, A; Nakamura, H; Origuchi, T	1
Hu, J; Liu, H; Liu, X; Wang, G; Xie, L	1
Beringer, PM; Burckart, GJ; Gill, M; Hidayat, L; Kriengkauykiat, J; Liu, S; Louie, S; Rao, PA; Shapiro, B; Synold, T; Zhang, X	1
Barletta, J; Bergström, M; Blomquist, G; Långström, B; Syvänen, S	1
Böhlke, M; Henry, K; Kim, J; Maher, TJ; Sani, SN; Stricker-Krongrad, A	1
Imasaka, T; Kaneta, T; Mbuna, J	1
Giacomini, KM; Lamoureux, F; Levoir, L; Marquet, P; Picard, N; Yee, SW	1
Jakob, I; Molinas, A; Sicard, G	1
Ariyawansa, J; Curtin, C; Devineni, D; Di Prospero, NA; Mamidi, RN; Murphy, J; Rothenberg, P; Stieltjes, H; Vaccaro, N; Wajs, E; Wang, SS; Weiner, S	1
Bonifacio, L; Covington, P; Davenport, JM; McIntyre, G; Venitz, J	1
Bai, P; Chen, M; Deng, X; Hu, J; Miao, P; Xu, Y; Yin, H; Yin, J	1
Aizawa, S; Harada, T; Hasegawa, H; Naito, M; Ohashi, A; Saeki, Y; Takahashi, T	1

Reviews

4 review(s) available for probenecid and cyclosporine

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug interactions with fluoroquinolones. The American journal of medicine, 1991, Dec-30, Volume: 91, Issue:6A Topics: 4-Quinolones; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Cyclosporine; Drug Interactions; Humans; Metals; Probenecid; Warfarin; Xanthines	1991

Trials

3 trial(s) available for probenecid and cyclosporine

Article	Year
Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis. Pharmacotherapy, 2008, Volume: 28, Issue:7 Topics: Adult; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Contrast Media; Cyclosporine; Cystic Fibrosis; Dicloxacillin; Drug Interactions; Female; Glomerular Filtration Rate; Humans; Iothalamate Meglumine; Kidney; Male; Organic Anion Transporters; Polymorphism, Genetic; Probenecid; Prospective Studies	2008
Effects of rifampin, cyclosporine A, and probenecid on the pharmacokinetic profile of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in healthy participants. International journal of clinical pharmacology and therapeutics, 2015, Volume: 53, Issue:2 Topics: Adult; Canagliflozin; Cyclosporine; Drug Interactions; Female; Glucosides; Humans; Male; Probenecid; Rifampin; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes	2015
Effect of uptake transporters OAT3 and OATP1B1 and efflux transporter MRP2 on the pharmacokinetics of eluxadoline. Journal of clinical pharmacology, 2015, Volume: 55, Issue:5 Topics: Adult; Area Under Curve; Cross-Over Studies; Cyclosporine; Half-Life; Humans; Imidazoles; Liver-Specific Organic Anion Transporter 1; Metabolic Clearance Rate; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Phenylalanine; Probenecid	2015

Other Studies

46 other study(ies) available for probenecid and cyclosporine

Article	Year
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells. Pharmaceutical research, 2001, Volume: 18, Issue:2 Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium	2001
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer research, 2001, Oct-01, Volume: 61, Issue:19 Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium	2001
Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. Biochemical and biophysical research communications, 2003, Oct-10, Volume: 310, Issue:1 Topics: Animals; Catechin; Cell Line; Dogs; Drug Resistance, Multiple; Multidrug Resistance-Associated Proteins	2003
Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux. British journal of pharmacology, 2004, Volume: 143, Issue:7 Topics: Algorithms; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beverages; Biological Transport, Active; Caco-2 Cells; Calcium Channel Blockers; Citrus; Cyclosporine; Food-Drug Interactions; HIV Protease Inhibitors; Humans; Immunosuppressive Agents; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Plant Extracts; Propionates; Quinolines; Saquinavir; Transfection; Verapamil; Vinblastine	2004
The potential for an interaction between MRP2 (ABCC2) and various therapeutic agents: probenecid as a candidate inhibitor of the biliary excretion of irinotecan metabolites. Drug metabolism and pharmacokinetics, 2002, Volume: 17, Issue:1 Topics:	2002
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide. The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47 Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins	2013
Impairment of tubular secretion of urate in renal transplant patients on cyclosporine. Nephron, 1995, Volume: 70, Issue:3 Topics: Adult; Benzofurans; Cyclosporine; Female; Humans; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Prevalence; Probenecid; Pyrazinamide; Retrospective Studies; Uric Acid; Uricosuric Agents	1995
Effect of nifedipine on tubular handling of uric acid in transplanted kidney on cyclosporine A treatment. Nephron, 1995, Volume: 70, Issue:1 Topics: Adolescent; Adult; Child; Creatinine; Cyclosporine; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Ion Transport; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Male; Nifedipine; Probenecid; Uric Acid	1995
Detection of P-glycoprotein in the Golgi apparatus of drug-untreated human melanoma cells. International journal of cancer, 1998, Mar-16, Volume: 75, Issue:6 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Compartmentation; Cells, Cultured; Cyclosporine; DNA-Binding Proteins; Doxorubicin; Fluorescent Antibody Technique, Indirect; Gene Expression; Golgi Apparatus; Humans; Melanoma; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Probenecid; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured	1998
Estimation of drug resistance by flow cytometry. Methods in molecular biology (Clifton, N.J.), 1998, Volume: 91 Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Genistein; Leukemia L5178; Mice; Probenecid; Recombinant Proteins; Rhodamine 123; Rhodamines; Transfection; Tumor Cells, Cultured; Verapamil	1998
Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells. Journal of neurochemistry, 1998, Volume: 71, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzbromarone; Brain; Capillaries; Carcinogens; Cell Line, Transformed; Colchicine; Cyclosporine; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genistein; Gout Suppressants; Immunoblotting; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Polymerase Chain Reaction; Probenecid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfinpyrazone; Uricosuric Agents; Vinblastine; Vincristine	1998
rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger. The American journal of physiology, 1999, Volume: 277, Issue:6 Topics: Animals; Biological Transport; Carrier Proteins; Cell Membrane; Cells, Cultured; Cyclosporine; Dogs; Female; Gene Library; In Vitro Techniques; Kinetics; Membrane Potentials; Niacinamide; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 2; Probenecid; Quinacrine; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Xenopus laevis	1999
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections. Bone marrow transplantation, 2001, Volume: 28, Issue:9 Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Evaluation; Eye Infections, Viral; Female; Foscarnet; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Probenecid; Recurrence; Safety; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Uveitis, Anterior; Viral Load; Viremia; Vomiting	2001
The influence of P-glycoprotein on morphine transport in Caco-2 cells. Comparison with paclitaxel. European journal of pharmacology, 2002, Apr-05, Volume: 440, Issue:1 Topics: Analgesics, Opioid; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Buthionine Sulfoximine; Caco-2 Cells; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Genistein; Glutathione; Humans; Indomethacin; Morphine; Paclitaxel; Probenecid; Progesterone; Time Factors; Verapamil	2002
Human intestinal Caco-2 cells display active transport of benzo[a]pyrene metabolites. Chemico-biological interactions, 2003, Jan-06, Volume: 142, Issue:3 Topics: Adenosine Triphosphate; Aryl Hydrocarbon Hydroxylases; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Benzoflavones; Biological Transport, Active; Caco-2 Cells; Cell Polarity; Cyclosporine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Enterocytes; Gene Expression; Humans; Models, Biological; Probenecid; Propionates; Quinolines; Verapamil; Vinblastine	2003
Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3 Topics: Acridines; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Cell Line; Cyclosporine; Cytosol; Gemfibrozil; Isoquinolines; Lysosomes; Macrophages; Mice; Microscopy, Confocal; Monensin; Probenecid; Tetrahydroisoquinolines; Verapamil	2003
Sulfate conjugating and transport functions of MDCK distal tubular cells. Kidney international, 2003, Volume: 63, Issue:3 Topics: Animals; Biological Transport; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Glutathione; Harmine; Humans; Immunosuppressive Agents; Kidney Tubules, Distal; Leukotriene Antagonists; Liver; Membrane Transport Proteins; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Probenecid; Propionates; Quinolines; Radiation-Protective Agents; Radiation-Sensitizing Agents; Sulfates; Uricosuric Agents	2003
UV or X-irradiation increases the cytoplasmic accumulation of rhodamine 123 in various cancer cell lines. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:8 Topics: Apoptosis; ATP-Binding Cassette Transporters; Cell Death; Cell Line; Cyclosporine; Cytoplasm; Flow Cytometry; Humans; Lymphocytes; Phenotype; Probenecid; Radiation Dosage; Radiation, Ionizing; Rhodamines; Sulfinpyrazone; Tumor Cells, Cultured; Ultraviolet Rays; Verapamil; X-Rays	2003
Potential roles of P-gp and calcium channels in loperamide and diphenoxylate transport. Toxicology and applied pharmacology, 2003, Nov-15, Volume: 193, Issue:1 Topics: Antidiarrheals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Calcium Channels; Cyclosporine; Cyclosporins; Diphenoxylate; Drug Interactions; Humans; Loperamide; Narcotics; Probenecid; Sulfinpyrazone; Verapamil	2003
Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:3 Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Bile; Cyclosporine; Erythromycin; Hyperbilirubinemia; Immunosuppressive Agents; Intestinal Mucosa; Kidney; Liver; Male; Mitochondrial Proteins; Probenecid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renal Agents; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Tissue Distribution	2004
Hepatobiliary excretion of berberine. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4 Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Berberine; Bile; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Glucuronides; Half-Life; Injections, Intravenous; Liver; Male; Methylation; Microdialysis; Organic Cation Transport Proteins; Proadifen; Probenecid; Quinidine; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Time Factors	2004
Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines. Leukemia research, 2004, Volume: 28, Issue:6 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bronchodilator Agents; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Probenecid; Propionates; Quinolines; Rhodamine 123; Tumor Cells, Cultured	2004
Efficacy of probenecid for a patient with juvenile dermatomyositis complicated with calcinosis. The Journal of rheumatology, 2006, Volume: 33, Issue:8 Topics: Anti-Inflammatory Agents; Calcinosis; Child; Cyclosporine; Dermatomyositis; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Knee Joint; Male; Prednisolone; Probenecid; Radiography; Range of Motion, Articular; Treatment Outcome; Uricosuric Agents	2006
Possible multiple transporters were involved in hepatobiliary excretion of antofloxacin in rats. Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:6 Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bile; Biological Transport; Cimetidine; Cyclosporine; Diclofenac; Enzyme Inhibitors; Erythromycin; Liver; Male; Membrane Transport Proteins; Ofloxacin; Probenecid; Rats; Rats, Sprague-Dawley; Uricosuric Agents	2007
PET-evaluated transport of [11C]hydroxyurea across the rat blood-brain barrier--lack of influence of cyclosporin and probenecid. Drug metabolism letters, 2007, Volume: 1, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hydroxyurea; Male; Mannitol; Positron-Emission Tomography; Probenecid; Rats; Rats, Sprague-Dawley; Tissue Distribution; Verapamil	2007
The effects of drug transporter inhibitors on the pharmacokinetics and tissue distribution of methotrexate in normal and tumor-bearing mice: a microdialysis study. Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:1 Topics: Animals; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cyclosporine; Drug Delivery Systems; Drug Interactions; Female; Humans; Methotrexate; Mice; Mice, Nude; Microdialysis; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Probenecid; Tissue Distribution; Xenograft Model Antitumor Assays	2010
Micellar electrokinetic chromatographic analysis for in vitro accumulation of anthracyclines enhanced by inhibitors of cell membrane transporter-proteins in cancer cells. Biomedical chromatography : BMC, 2011, Volume: 25, Issue:10 Topics: Biological Transport, Active; Cell Line, Tumor; Cellular Structures; Chromatography, Micellar Electrokinetic Capillary; Cyclosporine; Daunorubicin; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Probenecid; Verapamil	2011
Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters. Xenobiotica; the fate of foreign compounds in biological systems, 2011, Volume: 41, Issue:9 Topics: Caco-2 Cells; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Everolimus; HEK293 Cells; Humans; Immunosuppressive Agents; Inhibitory Concentration 50; Intestinal Mucosa; Intestines; Liver; Organic Anion Transporters; Probenecid; Sirolimus; Transfection	2011
Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium. PloS one, 2012, Volume: 7, Issue:5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Cyclosporine; Female; Fluoresceins; Gene Expression; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Olfactory Mucosa; Olfactory Receptor Neurons; Probenecid; Propionates; Quinolines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Verapamil	2012
ABC transporters affect the elimination and toxicity of CdTe quantum dots in liver and kidney cells. Toxicology and applied pharmacology, 2016, 07-15, Volume: 303 Topics: Animals; ATP-Binding Cassette Transporters; Cadmium Compounds; Cell Line; Cell Survival; Cyclosporine; Dogs; Hep G2 Cells; Humans; Kidney; Liver; Madin Darby Canine Kidney Cells; Oligopeptides; Probenecid; Propionates; Quantum Dots; Quinolines; Rifampin; RNA, Messenger; Tellurium	2016
Tetrahydrobiopterin Supplementation: Elevation of Tissue Biopterin Levels Accompanied by a Relative Increase in Dihydrobiopterin in the Blood and the Role of Probenecid-Sensitive Uptake in Scavenging Dihydrobiopterin in the Liver and Kidney of Rats. PloS one, 2016, Volume: 11, Issue:10 Topics: Animals; Bile; Biopterins; Brain; Cyclosporine; Erythrocytes; Female; Kidney; Liver; Male; Nitric Oxide Synthase; Probenecid; Rats	2016