Page last updated: 2024-08-16

probenecid and cefuroxime

probenecid has been researched along with cefuroxime in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kokue, EI; Soback, S; Ziv, G1
Baddour, LM; Cocchetto, DM; Gibbs, RS; Mertz, G; Noble, RC1
Das, RP; Jones, K; Robinson, AJ; Timmins, DJ1
Fong, IW; Hinton, NA; Linton, W; Simbul, M1
Ansink-Schipper, MC; Michel, MF; Schift, R; Stolz, E; van Joost, T; van Ulsen, J; Woudstra, RK1
Gottlieb, A; Mills, J1
Mattie, H; Van Strijen, E; Verhagen, CA1
Garton, AM; Gilpin, J; Marrelli, M; Rennie, RP; Shafran, SD1
Desai, A; Mopkar, O; Rao, PP1
Bingham, JS; Das, R; Oriel, JD; Ridgway, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for probenecid and cefuroxime

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for probenecid and cefuroxime

ArticleYear
Clinical comparison of single-oral-dose cefuroxime axetil and amoxicillin with probenecid for uncomplicated gonococcal infections in women.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonorrhea; Humans; Middle Aged; Probenecid

1989
Cefuroxime axetil to treat gonorrhea.
    Genitourinary medicine, 1988, Volume: 64, Issue:6

    Topics: Ampicillin; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Probenecid; Random Allocation

1988
Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2

    Topics: Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Probenecid; Prospective Studies; Random Allocation

1986
Comparison of oral treatment of uncomplicated urogenital and rectal gonorrhoea with cefuroxime axetil ester or clavulanic acid potentiated amoxycillin (Augmentin).
    Genitourinary medicine, 1986, Volume: 62, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefuroxime; Cephalosporins; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Middle Aged; Probenecid; Random Allocation

1986
Cefuroxime axetil for treatment of uncomplicated gonorrhea.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Gonorrhea; Humans; Male; Middle Aged; Probenecid; Random Allocation; Rectal Diseases; Urethritis

1986
Comparative trial to evaluate the efficacy and tolerability of cefuroxime 250mg with probenecid 250mg with cefuroxime 500mg in the management of community acquired pneumonia, acute bronchitis and acute exacerbation of chronic bronchitis.
    Journal of the Indian Medical Association, 2000, Volume: 98, Issue:10

    Topics: Acute Disease; Adult; Bronchitis; Cefuroxime; Cephalosporins; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Male; Pneumonia; Probenecid; Prospective Studies

2000

Other Studies

11 other study(ies) available for probenecid and cefuroxime

ArticleYear
Probenecid effect on cefuroxime pharmacokinetics in calves.
    Journal of veterinary pharmacology and therapeutics, 1989, Volume: 12, Issue:1

    Topics: Animals; Cattle; Cefuroxime; Cephalosporins; Drug Interactions; Half-Life; Injections, Intramuscular; Injections, Intravenous; Male; Probenecid

1989
The renal clearance of cefuroxime and ceftazidime and the effect of probenecid on their tubular excretion.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:2

    Topics: Administration, Oral; Adult; Ceftazidime; Cefuroxime; Humans; Injections, Intravenous; Kidney Tubules; Male; Probenecid

1994
Comparison of dose doubling with probenecid for sustaining serum cefuroxime levels.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Cefuroxime; Cephalosporins; Drug Interactions; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Probenecid; Renal Agents

1997
A comparative trial of cefuroxime axetil and ampicillin plus probenecid in the treatment of acute gonococcal infection.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Cefuroxime; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Probenecid

1989
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship

2013