Page last updated: 2024-08-16

probenecid and cefoxitin

probenecid has been researched along with cefoxitin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199014 (51.85)18.7374
1990's2 (7.41)18.2507
2000's6 (22.22)29.6817
2010's5 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Davies, RO; Holmes, GI; Martin, CM; Rogers, D; Schrogie, JJ; Skeggs, H; Yeh, KC1
Berg, SW; Harrison, WO; Kilpatrick, ME; McCutchan, JA1
Bint, AJ; Holt, HA; Reeves, DS; Stocks, PJ1
Bint, AJ; Holt, HA; Reeves, DS1
Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD1
Bombardt, PA; Bothwell, WM; Cathcart, KS1
Adams, WJ; Cathcart, KS; Griffith, DL; Ko, H; Peters, GR1
Lee, CT; Lim, KB; Sng, EH; Tan, T; Tham, SN; Thirumoorthy, T1
Axelrod, JL; Kochman, RS1
Arvidsson, A; Borgå, O; Kager, L; Pieper, R1
Bullock, DW; Bywater, MJ; Holt, HA; Reeves, DS; Thornhill, DP; White, LO1
Reeves, DS; Thornhill, DP1
Cherubin, C; Humbert, G; Leroy, A; Rogez, JP1
Abrams, WB; Ferguson, RK; Holbrook, AM; Rogers, JD; Schrogie, JJ; Vlasses, PH1
Berkeley, A; Binder, D; Faro, S; Gordon, S; Martens, MG; Yarborough, DR1
Levenson, D1
Amortegui, A; Haggerty, CL; Hendrix, SL; Hillier, SL; Holley, RL; Ness, RB; Peipert, J; Randall, H; Sondheimer, SJ; Soper, DE; Sweet, RL; Trucco, G1
Goldberg, AD; Goodwin, CS; Martin, CM; Raftery, EB; Skeggs, H; Till, AE1
Bass, DC; Kip, KE; Nelson, DB; Ness, RB; Peipert, JF; Richter, HE; Schubeck, D; Soper, DE; Trautmann, GM; Trout, W1
Bass, D; Haggerty, C; Ness, RB; Trent, M1

Reviews

2 review(s) available for probenecid and cefoxitin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Bioavailability and pharmacokinetics of cefoxitin sodium.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:B

    Topics: Absorption; Animals; Biological Availability; Cefoxitin; Cephalosporins; Chemical Phenomena; Chemistry; Drug Interactions; Haplorhini; Humans; Kidney Diseases; Kinetics; Mice; Probenecid; Protein Binding; Rats

1978

Trials

11 trial(s) available for probenecid and cefoxitin

ArticleYear
Cefoxitin as a single-dose treatment for urethritis caused by penicillinase-producing Neisseria gonorrhoeae.
    The New England journal of medicine, 1979, Sep-06, Volume: 301, Issue:10

    Topics: beta-Lactamases; Cefoxitin; Cephalosporins; Follow-Up Studies; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin G Procaine; Penicillin Resistance; Penicillinase; Probenecid; Urethritis

1979
Cefoxitin sodium: a clinical and pharmacological study.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:B

    Topics: Adult; Aged; Bacterial Infections; Cefoxitin; Cephalosporins; Child; Clinical Trials as Topic; Drug Interactions; Female; Humans; Male; Middle Aged; Probenecid; Time Factors

1978
A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis.
    American journal of obstetrics and gynecology, 1991, Volume: 164, Issue:5 Pt 2

    Topics: Acute Disease; Adult; Ambulatory Care; Cefoxitin; Chi-Square Distribution; Chlamydia Infections; Chlamydia trachomatis; Doxycycline; Drug Therapy, Combination; Female; Gonorrhea; Humans; Ofloxacin; Probenecid; Salpingitis

1991
Pharmacokinetics of intravenously administered cefmetazole and cefoxitin and effects of probenecid on cefmetazole elimination.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:3

    Topics: Adult; Cefmetazole; Cefoxitin; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Male; Middle Aged; Probenecid

1989
Renal elimination of cefoxitin and effect of probenecid after single and repeated doses.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 7, Issue:4

    Topics: Adult; Aged; Cefoxitin; Clinical Trials as Topic; Creatinine; Dose-Response Relationship, Drug; Half-Life; Humans; Kidney Tubules; Kinetics; Middle Aged; Probenecid

1981
Effect of orally administered probenecid on the pharmacokinetics of cefoxitin.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:5

    Topics: Administration, Oral; Adult; Cefoxitin; Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Metabolic Clearance Rate; Probenecid; Time Factors

1980
Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. Ambulatory PID Research Group.
    Southern medical journal, 1993, Volume: 86, Issue:6

    Topics: Adolescent; Adult; Ambulatory Care; Cefoxitin; Chlamydia Infections; Chlamydia trachomatis; Doxycycline; Drug Therapy, Combination; Female; Gonorrhea; Humans; Middle Aged; Ofloxacin; Pelvic Inflammatory Disease; Probenecid; Treatment Outcome

1993
Endometritis does not predict reproductive morbidity after pelvic inflammatory disease.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:1

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Cefoxitin; Chlamydia Infections; Doxycycline; Endometritis; Endometrium; Female; Gonorrhea; Humans; Infertility, Female; Odds Ratio; Pelvic Inflammatory Disease; Pregnancy; Probenecid; Time Factors

2003
Effects of rate of infusion and probenecid on serum levels, renal excretion, and tolerance of intravenous doses of cefoxitin in humans: comparison with cephalothin.
    Antimicrobial agents and chemotherapy, 1974, Volume: 6, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Cefoxitin; Cephalothin; Cross-Over Studies; Drug Interactions; Humans; Kidney; Male; Microbial Sensitivity Tests; Probenecid

1974
Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease?
    American journal of obstetrics and gynecology, 2008, Volume: 198, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Cefoxitin; Dose-Response Relationship, Drug; Doxycycline; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infertility, Female; Inflammation Mediators; Infusions, Intravenous; Pain Measurement; Pelvic Inflammatory Disease; Predictive Value of Tests; Probability; Probenecid; Proportional Hazards Models; Recurrence; Severity of Illness Index; Time Factors; Treatment Outcome

2008
Recurrent PID, subsequent STI, and reproductive health outcomes: findings from the PID evaluation and clinical health (PEACH) study.
    Sexually transmitted diseases, 2011, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefoxitin; Chronic Pain; Doxycycline; Female; Follow-Up Studies; Humans; Infertility, Female; Pelvic Inflammatory Disease; Pelvic Pain; Pregnancy; Pregnancy Complications; Probenecid; Recurrence; Reproductive Health; Sexually Transmitted Diseases; Treatment Outcome; United States; Uricosuric Agents; Young Adult

2011

Other Studies

14 other study(ies) available for probenecid and cefoxitin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship

2013
Effect of probenecid on serum cefoxitin concentrations.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:6

    Topics: Adult; Cefoxitin; Cephalosporins; Drug Interactions; Female; Half-Life; Humans; Probenecid

1977
An on-line, column-switching high-performance liquid chromatographic procedure for the removal of probenecid from human plasma, serum, or urine in the quantitative determination of cefmetazole or cefoxitin.
    Journal of pharmaceutical and biomedical analysis, 1989, Volume: 7, Issue:8

    Topics: Automation; Calibration; Cefmetazole; Cefoxitin; Chromatography, High Pressure Liquid; Humans; Probenecid; Reproducibility of Results

1989
Single dose cefoxitin in treating uncomplicated gonorrhoea caused by penicillinase producing Neisseria gonorrhoeae (PPNG) and non-PPNG strains.
    Genitourinary medicine, 1986, Volume: 62, Issue:4

    Topics: Cefoxitin; Drug Therapy, Combination; Female; Gonorrhea; Humans; Injections, Intramuscular; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillinase; Probenecid

1986
Cefoxitin levels in human aqueous humor.
    American journal of ophthalmology, 1980, Volume: 90, Issue:3

    Topics: Aqueous Humor; Cataract Extraction; Cefoxitin; Endophthalmitis; Humans; Probenecid; Surgical Wound Infection

1980
The effect of probenecid on the pharmacokinetics and distribution of cefoxitin in healthy volunteers.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:4

    Topics: Adult; Cefoxitin; Drug Interactions; Humans; Kinetics; Male; Middle Aged; Probenecid

1981
Effect of probenecid on renal elimination of cefoxitin.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 8, Issue:5

    Topics: Cefoxitin; Drug Interactions; Humans; Probenecid

1981
Cefoxitin concentrations in the cerebrospinal fluids of patients with meningitis.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Bacterial Infections; Blood Urea Nitrogen; Cefoxitin; Humans; Kidney; Meningitis; Meningitis, Aseptic; Middle Aged; Probenecid; Time Factors

1980
Outpatient pelvic inflammatory disease treatment as effective as inpatient care, study finds.
    Report on medical guidelines & outcomes research, 2002, Jun-14, Volume: 13, Issue:11

    Topics: Ambulatory Care; Cefoxitin; Cost Savings; Doxycycline; Female; Hospitalization; Humans; Infertility; Inpatients; Outpatients; Pelvic Inflammatory Disease; Practice Guidelines as Topic; Probenecid; Quality of Health Care; Randomized Controlled Trials as Topic; United States

2002