probenecid has been researched along with cefotaxime in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bowie, WR; Lefebvre, K; Megran, DW; Willetts, V | 1 |
| Calderón, E; Conde, CJ; de la Cruz, R; Hirata, C; Narcio, L | 1 |
| Heel, RC; Richards, DM | 1 |
| Bourne, DW; Cao, GR; English, PB; Filippich, LJ; Guerrini, VH | 2 |
| Hirose, T; Mine, Y; Nakamoto, S; Sakamoto, H | 1 |
| Bax, RP; Bywater, MJ; Holt, HA; Ings, RM; Reeves, DS; White, LO | 1 |
| Backhaus, A; Meyer-Rohn, J | 1 |
| Adam, D; Timmler, R | 1 |
| Goh, CL; Rajan, VS; Sng, EH; Thirumoorthy, T | 1 |
| Beville, R; Lutz, B; Mogabgab, WJ; Parks, D; Pauling, B | 1 |
| Gottlieb, A; Mills, J; Slutkin, G | 1 |
| Quinn, D; Rollins, DE; Sennello, LT; Sonders, RC; Tolman, KG | 1 |
| LeBel, M; Lewis, GP; Paone, RP | 1 |
| Nikoskelainen, J; Oksi, J; Viljanen, MK | 1 |
| Anzai, N; Babu, E; Endou, H; Enomoto, A; Huang, XL; Khamdang, S; Narikawa, S; Noshiro, R; Onozato, ML; Piyachaturawat, P; Takeda, M; Tojo, A | 1 |
2 review(s) available for probenecid and cefotaxime
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Ceftizoxime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biotransformation; Blood Coagulation; Cefotaxime; Ceftizoxime; Drug Synergism; Ethanol; Humans; Intestinal Absorption; Kidney Diseases; Kinetics; Probenecid; Tissue Distribution | 1985 |
7 trial(s) available for probenecid and cefotaxime
| Article | Year |
|---|---|
Single-dose oral cefixime versus amoxicillin plus probenecid for the treatment of uncomplicated gonorrhea in men.
Topics: Adolescent; Adult; Amoxicillin; Cefixime; Cefotaxime; Gonorrhea; Humans; Male; Probenecid; Randomized Controlled Trials as Topic; Urethritis | 1990 |
Treatment of ordinary and penicillinase-producing strains of Neisseria gonorrhoeae in Mexico City.
Topics: Adolescent; Adult; Cefotaxime; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neisseria gonorrhoeae; Penicillin G; Penicillin G Procaine; Probenecid; Random Allocation; Spectinomycin; Urethritis | 1987 |
Ceftriaxone in the treatment of ordinary and penicillinase-producing strains of Neisseria gonorrhoeae.
Topics: Cefotaxime; Ceftriaxone; Clinical Trials as Topic; Gonorrhea; Humans; Kanamycin; Male; Neisseria gonorrhoeae; Penicillinase; Probenecid; Urethritis | 1982 |
Comparison of ceftizoxime and penicillin for the treatment of uncomplicated gonorrhoea.
Topics: Adolescent; Adult; Cefotaxime; Ceftizoxime; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neisseria gonorrhoeae; Penicillin G Procaine; Probenecid | 1982 |
Ceftizoxime for treatment of gonorrhoea.
Topics: Cefotaxime; Ceftizoxime; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin G Procaine; Probenecid | 1982 |
Effect of probenecid on the pharmacokinetics of ceftizoxime.
Topics: Adult; Cefotaxime; Ceftizoxime; Drug Interactions; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney Tubules; Male; Probenecid | 1983 |
Comparison of oral cefixime and intravenous ceftriaxone followed by oral amoxicillin in disseminated Lyme borreliosis.
Topics: Administration, Oral; Adult; Amoxicillin; Cefixime; Cefotaxime; Ceftriaxone; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intravenous; Lyme Disease; Penicillins; Probenecid; Renal Agents; Treatment Outcome | 1998 |
13 other study(ies) available for probenecid and cefotaxime
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship | 2013 |
Effect of probenecid on the pharmacokinetics of cefotaxime in sheep.
Topics: Animals; Cefotaxime; Female; Half-Life; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Kinetics; Probenecid; Sheep | 1985 |
Mechanism of renal excretion of FK027 in dogs and rabbits.
Topics: Absorption; Animals; Cefixime; Cefotaxime; Dogs; Kidney; Male; Metabolic Clearance Rate; p-Aminohippuric Acid; Probenecid; Rabbits; Species Specificity | 1985 |
The human pharmacokinetics of cefotaxime and its metabolites and the role of renal tubular secretion on their elimination.
Topics: Adult; Blood Proteins; Cefotaxime; Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Humans; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Kidney Tubules; Kinetics; Lidocaine; Male; Middle Aged; Probenecid; Protein Binding; Time Factors | 1985 |
Pharmacokinetics of cefotaxime and probenecid in sheep with normal and reduced renal function.
Topics: Animals; Cefotaxime; Female; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Injections, Intravenous; Kidney Diseases; Kidney Function Tests; Kinetics; Probenecid; Renal Circulation; Sheep; Sheep Diseases | 1984 |
The treatment of gonococcal urethritis with cefotaxime [proceedings].
Topics: Cefotaxime; Cephalosporins; Drug Therapy, Combination; Gonorrhea; Humans; Male; Probenecid; Urethritis | 1980 |
[Pharmacokinetics of ceftizoxime with and without probenecid].
Topics: Adult; Aged; Cefotaxime; Ceftizoxime; Drug Interactions; Female; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Probenecid | 1982 |
Effect of probenecid on the pharmacokinetics of cefmenoxime.
Topics: Adult; Bile; Cefmenoxime; Cefotaxime; Drug Interactions; Humans; Kidney; Kinetics; Male; Probenecid | 1983 |
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Cefadroxil; Cefamandole; Cefazolin; Cefoperazone; Cefotaxime; Ceftriaxone; Cell Line; Cell Survival; Cephaloridine; Cephalosporins; Cephalothin; Dinoprost; Dose-Response Relationship, Drug; Humans; Kinetics; Mice; Mice, Transgenic; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Transfection; Uricosuric Agents | 2003 |