Page last updated: 2024-08-16

probenecid and cefazolin

probenecid has been researched along with cefazolin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's1 (4.35)18.2507
2000's11 (47.83)29.6817
2010's6 (26.09)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Tune, BM1
Bor, A; Soback, S; Ziv, G1
Ashcraft, SM; Donecker, JM; Sams, RA1
Brown, G; Clarke, AM; Zemcov, SJ1
Athan, E; Chambers, F; Gibson, K; Grayson, ML; McDonald, M; Munckhof, WJ; Paull, P1
Anzai, N; Babu, E; Endou, H; Enomoto, A; Huang, XL; Khamdang, S; Narikawa, S; Noshiro, R; Onozato, ML; Piyachaturawat, P; Takeda, M; Tojo, A1
Dillon, EC; Spina, SP1
Cox, VC; Zed, PJ1
Edwards, J; Green, P; Haase, D1
Khangura, S; Kissoon, N; Kodeeswaran, T; Wallace, J1
Mitsuoka, K; Nakakariya, M; Nakanishi, T; Shima, Y; Shirasaka, Y; Tamai, I1
Bader, MS; Hawboldt, J; Twells, L1
Campbell, SG; Dalen, D; Eppler, J; Fry, A; Zed, PJ1
Begg, EJ; Chin, PKL; Everts, R; Moore, GA; Zhang, M1
Aliter, H; El Khateeb, O; Nasser, AS; Stewart, K1

Reviews

2 review(s) available for probenecid and cefazolin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Once-daily cefazolin and probenecid for skin and soft tissue infections.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3

    Topics: Anti-Bacterial Agents; Biological Availability; Cefazolin; Half-Life; Humans; Male; Probenecid; Randomized Controlled Trials as Topic; Skin Diseases, Infectious; Soft Tissue Infections; Treatment Outcome; Uricosuric Agents

2004

Trials

3 trial(s) available for probenecid and cefazolin

ArticleYear
Effect of probenecid on cefazolin serum concentrations.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 31, Issue:6

    Topics: Adult; Cefazolin; Drug Interactions; Humans; Male; Probenecid

1993
Once-daily intravenous cefazolin plus oral probenecid is equivalent to once-daily intravenous ceftriaxone plus oral placebo for the treatment of moderate-to-severe cellulitis in adults.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Jun-01, Volume: 34, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Cefazolin; Ceftriaxone; Cellulitis; Cephalosporins; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Middle Aged; Placebos; Probenecid; Uricosuric Agents

2002
Effect of chronic probenecid therapy on cefazolin serum concentrations.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:5

    Topics: Administration, Oral; Adult; Aged; Cefazolin; Drug Interactions; Female; Humans; Injections, Intravenous; Male; Middle Aged; Probenecid

2003

Other Studies

18 other study(ies) available for probenecid and cefazolin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Gonorrhea. Recommended treatment schedules--1974.
    The Journal of pediatrics, 1975, Volume: 86, Issue:5

    Topics: Adolescent; Adult; Age Factors; Ampicillin; Anti-Bacterial Agents; Cefazolin; Child; Child, Preschool; Endophthalmitis; Erythromycin; Female; Follow-Up Studies; Gonorrhea; Hospitalization; Humans; Infant; Infant, Newborn; Male; Penicillin G; Penicillin G Procaine; Pharyngeal Diseases; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Salpingitis; Sex Factors; Spectinomycin; Tetracycline

1975
Relationship between the transport and toxicity of cephalosporins in the kidney.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:2

    Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Animals, Newborn; Biological Transport; Cefazolin; Cephaloridine; Cephalosporins; Dose-Response Relationship, Drug; Drug Administration Schedule; Guinea Pigs; Kidney Cortex; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Probenecid; Rabbits; Rats

1975
Clinical pharmacology of cefazolin in calves.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1987, Volume: 34, Issue:1

    Topics: Animals; Cattle; Cefazolin; Drug Interactions; Gram-Negative Bacteria; Kinetics; Male; Probenecid

1987
Pharmacokinetics of probenecid and the effect of oral probenecid administration on the pharmacokinetics of cefazolin in mares.
    American journal of veterinary research, 1986, Volume: 47, Issue:1

    Topics: Administration, Oral; Animals; Biological Availability; Cefazolin; Female; Horses; Injections, Intravenous; Kinetics; Probenecid

1986
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.
    European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Cefadroxil; Cefamandole; Cefazolin; Cefoperazone; Cefotaxime; Ceftriaxone; Cell Line; Cell Survival; Cephaloridine; Cephalosporins; Cephalothin; Dinoprost; Dose-Response Relationship, Drug; Humans; Kinetics; Mice; Mice, Transgenic; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Transfection; Uricosuric Agents

2003
A blistering disease: bullous erysipelas.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2006, Aug-01, Volume: 175, Issue:3

    Topics: Anti-Bacterial Agents; Blister; Cefazolin; Cellulitis; Diabetes Mellitus, Type 2; Erysipelas; Humans; Male; Middle Aged; Probenecid; Uricosuric Agents

2006
Management of cellulitis in a pediatric emergency department.
    Pediatric emergency care, 2007, Volume: 23, Issue:11

    Topics: Academic Medical Centers; Adjuvants, Pharmaceutic; Administration, Oral; Adolescent; Anti-Bacterial Agents; British Columbia; Case-Control Studies; Cefazolin; Cellulitis; Cephalexin; Child; Child, Preschool; Cloxacillin; Emergency Service, Hospital; Female; Humans; Infant; Infusions, Intravenous; Male; Patient Admission; Probenecid; Retrospective Studies; Staphylococcus aureus; Streptococcus pyogenes

2007
Organic anion transporter OAT1 is involved in renal handling of citrulline.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Biological Transport; Catecholamine Plasma Membrane Transport Proteins; Cefazolin; Cell Line; Citrulline; Glutarates; Humans; Kidney; Male; Models, Animal; Octamer Transcription Factor-1; Octamer Transcription Factor-2; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Probenecid; Rats; Rats, Wistar

2009
Risk factors of cellulitis treatment failure with once-daily intravenous cefazolin plus oral probenecid.
    Southern medical journal, 2011, Volume: 104, Issue:12

    Topics: Administration, Oral; Anti-Bacterial Agents; Cefazolin; Cellulitis; Chi-Square Distribution; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Logistic Models; Male; Middle Aged; Peripheral Vascular Diseases; Probenecid; Retrospective Studies; Risk Factors; Treatment Failure; Veins

2011
Intravenous cefazolin plus oral probenecid versus oral cephalexin for the treatment of skin and soft tissue infections: a double-blind, non-inferiority, randomised controlled trial.
    Emergency medicine journal : EMJ, 2018, Volume: 35, Issue:8

    Topics: Adjuvants, Pharmaceutic; Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Canada; Cefazolin; Cephalexin; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Probenecid; Prospective Studies; Soft Tissue Infections

2018
Simultaneous Determination of Cefalexin, Cefazolin, Flucloxacillin, and Probenecid by Liquid Chromatography-Tandem Mass Spectrometry for Total and Unbound Concentrations in Human Plasma.
    Therapeutic drug monitoring, 2018, Volume: 40, Issue:6

    Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aged; Aged, 80 and over; beta-Lactams; Cefazolin; Cephalexin; Child; Chromatography, High Pressure Liquid; Drug Monitoring; Floxacillin; Humans; Limit of Detection; Middle Aged; Plasma; Probenecid; Tandem Mass Spectrometry; Young Adult

2018
Successful drainage of periaortic graft abscess and transcatheter aortic valve replacement in the same setting-A hybrid approach.
    Journal of cardiac surgery, 2022, Volume: 37, Issue:11

    Topics: Abscess; Aged, 80 and over; Anti-Bacterial Agents; Aortic Valve; Aortic Valve Stenosis; Cefadroxil; Cefazolin; Drainage; Heart Valve Prosthesis; Humans; Male; Methicillin; Probenecid; Rifampin; Transcatheter Aortic Valve Replacement

2022