Compounds > probenecid

Page last updated: 2024-08-16

probenecid and cefadroxil anhydrous

probenecid has been researched along with cefadroxil anhydrous in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (5.26)	18.7374
1990's	1 (5.26)	18.2507
2000's	6 (31.58)	29.6817
2010's	10 (52.63)	24.3611
2020's	1 (5.26)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dominguez-Gil, A; Mariño, EL	1
Gimeno, MJ; Granero, L; Martínez, M; Peris, JE; Torres-Molina, F	1
Anzai, N; Babu, E; Endou, H; Enomoto, A; Huang, XL; Khamdang, S; Narikawa, S; Noshiro, R; Onozato, ML; Piyachaturawat, P; Takeda, M; Tojo, A	1
Hu, Y; Keep, RF; Ocheltree, SM; Shen, H; Smith, DE	1
Huh, Y; Keep, RF; Smith, DE	1
Aliter, H; El Khateeb, O; Nasser, AS; Stewart, K	1

Reviews

2 review(s) available for probenecid and cefadroxil anhydrous

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

17 other study(ies) available for probenecid and cefadroxil anhydrous

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The pharmacokinetics of cefadroxil associated with probenecid. International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:11 Topics: Adult; Bacillus subtilis; Biological Assay; Cefadroxil; Cephalexin; Drug Interactions; Humans; Kinetics; Probenecid	1981
Influence of probenecid on the renal excretion mechanisms of cefadroxil. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:2 Topics: Animals; Cefadroxil; Cephalosporins; Drug Interactions; Kidney; Male; Metabolic Clearance Rate; Probenecid; Rats; Rats, Wistar; Renal Agents	1996
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2 Topics: Animals; Anti-Bacterial Agents; Biological Transport; Cefadroxil; Cefamandole; Cefazolin; Cefoperazone; Cefotaxime; Ceftriaxone; Cell Line; Cell Survival; Cephaloridine; Cephalosporins; Cephalothin; Dinoprost; Dose-Response Relationship, Drug; Humans; Kinetics; Mice; Mice, Transgenic; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Transfection; Uricosuric Agents	2003
Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption, and brain penetration in mice. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7 Topics: Animals; Anti-Bacterial Agents; Biotransformation; Blood-Brain Barrier; Brain; Cefadroxil; Choroid Plexus; Drug Stability; Female; Injections, Intravenous; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Probenecid; Quinine; Symporters	2007
Impact of lipopolysaccharide-induced inflammation on the disposition of the aminocephalosporin cefadroxil. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12 Topics: Adjuvants, Pharmaceutic; Animals; Anti-Bacterial Agents; Area Under Curve; Cefadroxil; Gene Expression; Glomerular Filtration Rate; Inflammation; Kidney; Lipopolysaccharides; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Probenecid	2013
Successful drainage of periaortic graft abscess and transcatheter aortic valve replacement in the same setting-A hybrid approach. Journal of cardiac surgery, 2022, Volume: 37, Issue:11 Topics: Abscess; Aged, 80 and over; Anti-Bacterial Agents; Aortic Valve; Aortic Valve Stenosis; Cefadroxil; Cefazolin; Drainage; Heart Valve Prosthesis; Humans; Male; Methicillin; Probenecid; Rifampin; Transcatheter Aortic Valve Replacement	2022