Page last updated: 2024-08-16

probenecid and bilirubin

probenecid has been researched along with bilirubin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's3 (16.67)18.2507
2000's3 (16.67)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hagenbuch, B; Kullak-Ublick, GA; Meier, PJ; Stieger, B; Wolkoff, AW1
Strassburg, CP; Tukey, RH1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Arias, IM; Fleischner, G; Kamisaka, K; Kirsch, R1
Wiener, H1
Comin, EJ; Elías, MM; Ochoa, EJ; Rodríguez Garay, EA1
Kenwright, S; Levi, AJ1
De Schepper, J; Van der Stock, J1
Arias, IM; Gatmaitan, Z; Levi, AJ1
Klaassen, CD1
Ali, MA; Billing, BH1
Azevedo, I; Martel, F; Osswald, W1
Elías, MM; Mottino, AD; Ochoa, EJ1
Murakami, T; Nagai, J; Takano, M; Yokooji, T; Yumoto, R1
Mori, N; Murakami, T; Yokooji, T2

Reviews

3 review(s) available for probenecid and bilirubin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
[Experimental study on the urinary bilirubin excretion in the dog and its clinical significance].
    Verhandelingen - Koninklijke Vlaamse Academie voor Geneeskunde van Belgie, 1969, Volume: 31, Issue:2

    Topics: Animals; Bilirubin; Cholestasis; Creatinine; Diet; Dogs; Electrophoresis; Female; Glomerular Filtration Rate; Haptoglobins; Hemoglobins; Hemoglobinuria; Hemolysis; Injections, Intravenous; Iron Isotopes; Kidney Tubules; Liver; Male; Probenecid; Protein Binding; Time Factors

1969

Other Studies

15 other study(ies) available for probenecid and bilirubin

ArticleYear
Functional characterization of the basolateral rat liver organic anion transporting polypeptide.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:2

    Topics: Animals; Anion Transport Proteins; Bile Acids and Salts; Carrier Proteins; Female; In Vitro Techniques; Indocyanine Green; Ion Transport; Liver; Oocytes; Rats; Sulfobromophthalein; Xenopus laevis

1994
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
Structural and functional studies of ligandin, a major renal organic anion-binding protein.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:5

    Topics: Amino Acids; Aminohippuric Acids; Animals; Bilirubin; Binding, Competitive; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Gel; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Glutathione; Immunodiffusion; Kidney; Ligands; Male; Penicillin G; Penicillins; Phenolsulfonphthalein; Phlorhizin; Probenecid; Protein Binding; Proteins; Rats; Spectrophotometry; Sulfobromophthalein

1975
Heterogeneity of dog-liver glutathione S-transferases. Evidence for a unique temperature dependence of the catalytic process.
    European journal of biochemistry, 1986, Jun-02, Volume: 157, Issue:2

    Topics: Anilino Naphthalenesulfonates; Animals; Bilirubin; Bromcresol Green; Chromatography, Gel; Deoxycholic Acid; Dogs; Glutathione Transferase; Hydrogen-Ion Concentration; Isoelectric Focusing; Isoenzymes; Kinetics; Liver; Macromolecular Substances; Molecular Weight; Probenecid; Substrate Specificity; Sulfobromophthalein; Temperature

1986
Evidence for a secretory component in the handling of unconjugated bilirubin by the isolated perfused rat kidney.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:12

    Topics: Animals; Bilirubin; In Vitro Techniques; Kidney; Kinetics; Male; p-Aminohippuric Acid; Perfusion; Probenecid; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet

1985
Impairment of hepatic uptake of rifamycin antibiotics by probenecid, and its therapeutic implications.
    Lancet (London, England), 1973, Dec-22, Volume: 2, Issue:7843

    Topics: Administration, Oral; Animals; Bilirubin; Costs and Cost Analysis; Drug Synergism; Drug Therapy, Combination; Health Expenditures; Humans; In Vitro Techniques; Liver; Liver Function Tests; Male; Probenecid; Rats; Rifamycins; Sulfobromophthalein; Tuberculosis, Pulmonary

1973
Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Bile Acids and Salts; Bilirubin; Butyrophenones; Chromatography, Gel; Coloring Agents; Cytoplasm; Female; Guinea Pigs; Haplorhini; Humans; Indocyanine Green; Iodipamide; Iodobenzenes; Liver; Male; Mice; Novobiocin; Probenecid; Protein Binding; Proteins; Rats; Sheep; Sulfobromophthalein

1969
Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Chlorothiazide; Coloring Agents; Indocyanine Green; Male; Ouabain; Phenobarbital; Phenols; Probenecid; Procainamide; Rats; Succinates; Sulfathiazoles; Sulfobromophthalein

1970
Renal excretion of bilirubin by the rat.
    The American journal of physiology, 1968, Volume: 214, Issue:6

    Topics: Aminohippuric Acids; Animals; Bile Acids and Salts; Bilirubin; Diuresis; Kidney; Kidney Glomerulus; Male; Probenecid; Protein Binding; Rats; Sodium Salicylate; Sulfisoxazole

1968
Uptake of 3H-catecholamines by rat liver cells occurs mainly through a system which is distinct from uptake1 or uptake2.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:2

    Topics: Animals; Bilirubin; Catecholamines; Corticosterone; Desipramine; In Vitro Techniques; Liver; Male; Potassium; Probenecid; Quinolinium Compounds; Rats; Rats, Wistar; Sodium

1994
Transepithelial fate of bilirubin in the isolated rat kidney.
    Biochimica et biophysica acta, 1997, Jul-19, Volume: 1336, Issue:1

    Topics: Animals; Area Under Curve; Bilirubin; Epithelium; In Vitro Techniques; Kidney; Male; Niacin; Perfusion; Probenecid; Rats; Rats, Wistar

1997
Function of multidrug resistance-associated protein 2 in acute hepatic failure rats.
    European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3

    Topics: Adenosine Triphosphate; Animals; Area Under Curve; ATP-Binding Cassette Transporters; Bile; Bilirubin; Carbon Tetrachloride; Dinitrochlorobenzene; Glutathione; Glutathione Transferase; Hyperbilirubinemia; Ileum; Intestinal Mucosa; Intestines; Jejunum; Liver; Liver Failure, Acute; Male; Organ Size; Probenecid; Rats; Rats, Sprague-Dawley; Time Factors

2006
Modulated function of tissue efflux transporters under hyperbilirubinemia in rats.
    European journal of pharmacology, 2010, Jun-25, Volume: 636, Issue:1-3

    Topics: Animals; Bilirubin; Dinitrochlorobenzene; Gene Expression Regulation; Glutathione; Hyperbilirubinemia; Male; Membrane Transport Proteins; Probenecid; Rats; Rats, Sprague-Dawley

2010
Modulated pharmacokinetics and increased small intestinal toxicity of methotrexate in bilirubin-treated rats.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:2

    Topics: Alkaline Phosphatase; Animals; Biliary Tract; Bilirubin; Biological Transport; Drug Interactions; Hyperbilirubinemia; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methotrexate; Multidrug Resistance-Associated Proteins; Probenecid; Rats; Rats, Sprague-Dawley

2011