Page last updated: 2024-08-16

probenecid and aztreonam

probenecid has been researched along with aztreonam in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's6 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deighton Fimls, R; Mohanty, KC; Strachan, RG1
Imada, A; Kita, Y1
Deighton, R; Mohanty, KC; Strachan, RG1
Egger, HJ; Stoeckel, K; Weidekamm, E; Ziegler, WH1
Frantz, M; Platt, TB; Stern, M; Sugerman, AA; Swabb, EA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for probenecid and aztreonam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for probenecid and aztreonam

ArticleYear
A comparative study of aztreonam and procaine penicillin/probenecid in the treatment of uncomplicated gonorrhoea.
    Scandinavian journal of infectious diseases, 1988, Volume: 20, Issue:1

    Topics: Aztreonam; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Penicillin G; Penicillin G Procaine; Penicillinase; Probenecid; Random Allocation

1988
Single intramuscular injection of aztreonam in the treatment of uncomplicated gonorrhoea in women.
    Current medical research and opinion, 1987, Volume: 10, Issue:9

    Topics: Aztreonam; Drug Evaluation; Female; Gonorrhea; Humans; Injections, Intramuscular; Microbial Sensitivity Tests; Penicillin G; Probenecid

1987
Single-dose pharmacokinetics of Ro 17-2301 (AMA-1080), a monocyclic beta-lactam, in humans.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Clinical Trials as Topic; Dialysis; Feces; Half-Life; Humans; Kidney Glomerulus; Kinetics; Male; Probenecid; Protein Binding; Ultrafiltration

1984

Other Studies

10 other study(ies) available for probenecid and aztreonam

ArticleYear
Mechanism of renal excretion of carumonam in rats, rabbits, dogs, and monkeys.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Dogs; Female; Kidney; Lactams; Macaca fascicularis; Male; Metabolic Clearance Rate; Mice; Mice, Inbred ICR; Probenecid; Rabbits; Rats; Rats, Inbred Strains; Species Specificity

1987
Renal handling of the monobactam azthreonam in healthy subjects.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:5

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Aztreonam; Glomerular Filtration Rate; Half-Life; Humans; Infusions, Parenteral; Inulin; Kidney; Kidney Tubules; Male; Probenecid; Protein Binding

1983
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship

2013