Page last updated: 2024-08-16

probenecid and ascorbic acid

probenecid has been researched along with ascorbic acid in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19909 (40.91)18.7374
1990's6 (27.27)18.2507
2000's3 (13.64)29.6817
2010's4 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dehner, EJ; Martin, ET; Schwartz, JB1
Lorenzo, AV; Spector, R2
Jeppesen, CK; Nielsen, FS; Thorn, NA1
Huisman, JA; Raghoebar, M; van den Berg, WB; van Ginneken, CA1
Dresse, A; Gérardy, J; Quinaux, N1
Dayton, PG; Perel, JM; Weiss, MM1
Ferrier, B; Martin, M; Roch-Ramel, F1
Borden, M; Kaufman, IA; Nyhan, WL; Stapleton, FB1
Foster, JR; Fowler, LM; Lock, EA2
Anestis, DK; Ball, JG; Brown, PI; Hong, SK; Rankin, GO; Valentovic, MA1
Galla, HJ; Hakvoort, A; Haselbach, M1
Cueto, R; Freed, AN; Pryor, WA1
CONSTANT, MA; FALCH, J1
Belch, JJ; Carr, E; Davies, J; George, J; Struthers, A1
Austin, MD; Dibarnardi, AN; Hosick, PA; Hudson, MB; McAnulty, LS; McAnulty, SR; Milne, GL; Morrow, JD; Quindry, JC; Still, L1

Reviews

1 review(s) available for probenecid and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for probenecid and ascorbic acid

ArticleYear
High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid.
    Circulation, 2006, Dec-05, Volume: 114, Issue:23

    Topics: Acetylcholine; Aged; Allopurinol; Ascorbic Acid; Blood Pressure; Cardiac Output, Low; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitroprusside; Oxidative Stress; Probenecid; Regional Blood Flow; Uric Acid; Uricosuric Agents; Vasodilator Agents

2006

Other Studies

20 other study(ies) available for probenecid and ascorbic acid

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Intragranular starch: comparison of starch USP and modified cornstarch.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:2

    Topics: Acetaminophen; Ascorbic Acid; Biopharmaceutics; Cellulose; Chlorothiazide; Dihydroxyphenylalanine; Excipients; Hardness Tests; Kinetics; Methyldopa; Pressure; Probenecid; Solubility; Starch; Tablets

1975
Myo-inositol transport in the central nervous system.
    The American journal of physiology, 1975, Volume: 228, Issue:5

    Topics: Animals; Ascorbic Acid; Biological Transport, Active; Brain; Carbon Radioisotopes; Choroid Plexus; Chromatography, Paper; Glucose; In Vitro Techniques; Infusions, Parenteral; Inositol; Inulin; Kinetics; Mannitol; Probenecid; Rabbits; Sorbitol; Thiourea; Time Factors; Tritium

1975
Characteristics of ascorbic acid uptake by isolated ox neurohypophyseal nerve terminals and the influence of glucocorticoid and tri-iodothyronine on uptake.
    Acta physiologica Scandinavica, 1991, Volume: 141, Issue:1

    Topics: Animals; Ascorbic Acid; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cytochalasin B; Dopamine; Ethanol; Female; Glucocorticoids; Glucose; Hydrocortisone; Insulin; Male; Nerve Endings; Phlorhizin; Pituitary Gland, Posterior; Probenecid; Temperature; Triiodothyronine

1991
Characteristics of the transport of ascorbic acid into leucocytes.
    Life sciences, 1987, Feb-02, Volume: 40, Issue:5

    Topics: Adult; Ascorbic Acid; Biological Transport; Dehydroascorbic Acid; Glucose; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inflammation; Neutrophils; Probenecid; Temperature

1987
Ascorbic acid homeostasis in the central nervous system.
    The American journal of physiology, 1973, Volume: 225, Issue:4

    Topics: Animals; Ascorbic Acid; Biological Transport, Active; Brain; Carbon Radioisotopes; Choroid Plexus; Depression, Chemical; Dinitrophenols; Iodides; Models, Biological; Penicillins; Probenecid; Rabbits; Salicylates; Sulfates; Tritium; Uracil

1973
[Determination of noradrenaline, of dopamine and dihydroxyphenylacetic acid in certain nuclei of rat brain].
    Experientia, 1971, Jan-15, Volume: 27, Issue:1

    Topics: Animals; Ascorbic Acid; Catecholamines; Caudate Nucleus; Chromatography, Thin Layer; Dihydroxyphenylalanine; Dopamine; Female; Fluorometry; Haloperidol; Hypothalamus; Male; Norepinephrine; Phenylacetates; Probenecid; Rats; Reserpine; Tranylcypromine

1971
The effect of probenecid, phenylbutazone, and their analogs on the excretion of L-ascorbic acid in rats.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Animals; Ascorbic Acid; Carbon Isotopes; Galactose; Glucose; Hexoses; Male; Phenylbutazone; Probenecid; Rats

1966
Renal excretion of ascorbic acid in the rat: a micropuncture study.
    The American journal of physiology, 1983, Volume: 244, Issue:3

    Topics: Animals; Ascorbic Acid; Biological Transport; Glomerular Filtration Rate; Kidney; Kidney Tubules, Proximal; Kinetics; Male; Probenecid; Rats; Rats, Inbred Strains

1983
Renal pathogenesis of familial hyperuricemia: studies in two kindreds.
    Pediatric research, 1981, Volume: 15, Issue:11

    Topics: Adolescent; Ascorbic Acid; Humans; Kidney; Kidney Tubules; Male; Probenecid; Protein Binding; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrazinamide; Uric Acid

1981
Nephrotoxicity of 4-amino-3-S-glutathionylphenol and its modulation by metabolism or transport inhibitors.
    Archives of toxicology, 1994, Volume: 68, Issue:1

    Topics: Aminooxyacetic Acid; Animals; Ascorbic Acid; Blood Urea Nitrogen; gamma-Glutamyltransferase; Glutathione; Glycosuria; Ion Transport; Isoxazoles; Kidney; Lyases; Male; Oxidation-Reduction; Phenols; Probenecid; Proteinuria; Rats; Rats, Inbred F344; Sulfur Radioisotopes

1994
Effect of ascorbic acid, acivicin and probenecid on the nephrotoxicity of 4-aminophenol in the Fischer 344 rat.
    Archives of toxicology, 1993, Volume: 67, Issue:9

    Topics: Aminophenols; Animals; Antimetabolites; Ascorbic Acid; Isoxazoles; Kidney; Kidney Diseases; Kidney Function Tests; Liver; Male; Probenecid; Rats; Rats, Inbred F344

1993
4-Amino-2,6-dichlorophenol nephrotoxicity in the Fischer 344 rat: protection by ascorbic acid, AT-125, and aminooxyacetic acid.
    Toxicology and applied pharmacology, 1997, Volume: 147, Issue:1

    Topics: Aminooxyacetic Acid; Animals; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Chlorophenols; Drug Interactions; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Injections, Intraperitoneal; Isoxazoles; Kidney Cortex; Liver; Male; Probenecid; Rats; Rats, Inbred F344; Sulfhydryl Compounds

1997
Active transport properties of porcine choroid plexus cells in culture.
    Brain research, 1998, Jun-08, Volume: 795, Issue:1-2

    Topics: Animals; Anions; Ascorbic Acid; Bicarbonates; Biological Transport, Active; Blood-Brain Barrier; Body Fluids; Cell Polarity; Cells, Cultured; Choroid Plexus; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Epithelial Cells; Fluorescein; Inositol; Kinetics; Microscopy, Electron; Penicillin G; Penicillins; Phenolsulfonphthalein; Probenecid; Renal Agents; Riboflavin; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Swine

1998
Antioxidant transport modulates peripheral airway reactivity and inflammation during ozone exposure.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:5

    Topics: Airway Resistance; Aldehydes; Animals; Antioxidants; Ascorbic Acid; Biological Transport, Active; Bronchoalveolar Lavage Fluid; Cell Count; Chromans; Dogs; Inflammation; Male; Oxidants, Photochemical; Ozone; Peroxides; Probenecid; Proteins; Respiratory System; Uricosuric Agents

1999
PHOSPHATE AND PROTEIN CONCENTRATIONS OF INTRAOCULAR FLUIDS. I. EFFECT OF CARBONIC ANHYDRASE INHIBITION IN YOUNG AND OLD RABBITS.
    Investigative ophthalmology, 1963, Volume: 2

    Topics: Aging; Animals; Aqueous Humor; Ascorbic Acid; Bicarbonates; Blood Chemical Analysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dichlorphenamide; Eye Proteins; Lagomorpha; Phosphates; Probenecid; Rabbits; Research; Tetracaine; Vitreous Body

1963
Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2007, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Anaerobic Threshold; Antioxidants; Ascorbic Acid; Body Composition; Body Weight; Exercise; Ferric Compounds; Humans; Isoprostanes; Lactic Acid; Lipid Peroxidation; Male; Nitrates; Nitrites; Oxidation-Reduction; Oxidative Stress; Probenecid; Uric Acid; Uricosuric Agents

2007