Page last updated: 2024-08-16

probenecid and amoxicillin

probenecid has been researched along with amoxicillin in 82 studies

Research

Studies (82)

Timeframe	Studies, this research(%)	All Research%
pre-1990	39 (47.56)	18.7374
1990's	15 (18.29)	18.2507
2000's	8 (9.76)	29.6817
2010's	16 (19.51)	24.3611
2020's	4 (4.88)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Hopper, PK; Shaw, EJ; Slocombe, B; Symonds, MA; Thin, RN; Wong, J	1
Brathwaite, AR	1
St John, RK	1
Barbhaiya, R; Thin, RN; Turner, P; Wadsworth, J	1
Craft, JC; Feldman, WE; Nelson, JD	1
Békési, S; Münnich, D	1
Kanerva, L; Lassus, A; Renkonen, OV	1
Tapsall, JW; Walker, AM	1
de Koning, GA; Michel, MF; Stolz, E	1
Dajani, AS; Mohs, E; Nelson, JD; Plotkin, SA	1
Gray, IR	2
Gleich, LL; Kimmelman, CP; Linstrom, CJ	1
Johnson, RC; Luger, SW; Massarotti, EM; Messner, RP; Rahn, DW; Steere, AC; Wong, JB	1
Bair, GO	1
Berger, BW; Coleman, L; Johnson, RC; Kodner, C	1
Goldmeier, D; Hay, PE; Taylor-Robinson, D; Waldron, S	1
Conaty, SM; Dattwyler, RJ; Luft, BJ; Platkin, SP; Volkman, DJ	1
Bowie, WR; Lefebvre, K; Megran, DW; Willetts, V	1
Clay, JC; Mohanty, KC; Roberts, KN; Tovey, SJ; Veeravahu, M; Wanas, TM	1
Allen, MB; Barratt, A; Cole, RB; Fitzpatrick, RW	1
Happonen, HP; Ingervo, L; Jeskanen, L; Karkulahti, R; Karppinen, L; Lassus, A; Reitamo, S	1
Lutz, FB	1
Höglund, P; Paulsen, O; Schalén, C	1
Black, JR; Handsfield, HH; Hook, EW; Long, JM; Ray, BS; Verdon, MS; Wetherby, S; Zwickl, BE	1
Baddour, LM; Cocchetto, DM; Gibbs, RS; Mertz, G; Noble, RC	1
Lee, CT; Lim, KB; Sng, EH; Tan, T; Thirumoorthy, T	2
Fong, IW; Hinton, NA; Linton, W; Simbul, M	1
Gundersen, T; Melby, K; Ulshagen, K	1
Bor, A; Kurtz, B; Paz, R; Soback, S; Ziv, G	1
Ansink-Schipper, MC; Michel, MF; Schift, R; Stolz, E; van Joost, T; van Ulsen, J; Woudstra, RK	1
Csángó, PA; Furu, K; Gundersen, T; Melby, K; Solberg, VM	1
Gottlieb, A; Mills, J	1
Caranasos, GJ; Cluff, LE; Stewart, RB	1
Harrison, SM; Morrison, RE; Tramont, EC	1
Shanson, DC	1
Azadian, BS; Evans, BA; Key, PR	1
Lawrence, AG; Shanson, DC	1
Smithurst, BA	1
Wilkowske, CJ; Wright, AJ	1
Donovan, B	1
Edwards, LD; Gartner, T	1
Hajipieris, P; McNabb, R; Shanson, DC	1
Davies, B; Horton, R; Jackson, D; Staniforth, DH	1
Clarke, HL; Horton, R; Jackson, D; Staniforth, DH	1
Tight, RR; White, AC	1
Woodcock, K	1
Abraham, JH; Kalish, RA; Levin, RE; Liu, NY; Molloy, PJ; Schmid, CH; Steere, AC	1
Carbon, C; Dautrey, S; Farinotti, R; Huneau, JF; Ramon, J; Rubinstein, E; St Julien, L	1
Barnes, DL; Castaneda, YS; Cavenee, MR; Farris, JR; Spalding, TR; Wendel, GD	1
Augenbraun, MH; Bolan, G; Chiu, M; French, P; Hendershot, EF; Joesoef, MR; Johnson, SC; Larsen, S; Radolf, JD; Rolfs, RT; Rompalo, AM; Steen, E	1
Augenbraun, M; Joesoef, R; Johnson, R; Pope, V; Rolfs, R	1
Nikoskelainen, J; Oksi, J; Viljanen, MK	1
Barrett, J; Cihlar, T; Hill, G; Ho, ES; Liu, B; Oo, C; Prior, K; Ward, P; Wiltshire, H	1
Hayes, E	1
Augenbraun, M; Zellan, J	1
Fisk, RE; Goire, N; Mak, DB; Speers, DJ	1
Aoki, T; Gatanaga, H; Kikuchi, Y; Nishijima, T; Oka, S; Tanizaki, R; Teruya, K	1
Enriquez, RP; Lahra, MM	1
Comunián-Carrasco, G; Martí-Carvajal, AJ; Peña-Martí, GE	1
Alva-López, L; Ávila-Ramírez, J; Estrada-Lobato, E; Islas-Muñoz, B; Santillán-Doherty, P; Volkow-Fernández, P	1
Kobayashi, W; Kojima, E; Kuba, H; Matsumura, M	1
Fukushima, K; Ikeuchi, K; Imamura, A; Tanaka, M; Yajima, K	1
Arkell, P; Gilchrist, M; Holmes, AH; Hope, W; Rawson, TM; Riezk, A; Wheeler, G; Wilson, RC	1
Ando, N; Aoki, T; Gatanaga, H; Hiramoto, S; Inamura, N; Kikuchi, Y; Mizushima, D; Nemoto, T; Oka, S; Omata, K; Shiojiri, D; Takano, M; Tanuma, J; Teruya, K; Uemura, H; Watanabe, K; Yanagawa, Y	1

Reviews

7 review(s) available for probenecid and amoxicillin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Clinically desirable drug interactions. Annual review of pharmacology and toxicology, 1985, Volume: 25 Topics: Aminoglycosides; Amoxicillin; Ampicillin; Antacids; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Carbidopa; Diuretics; Drug Combinations; Drug Interactions; Drug Synergism; Humans; Hydroxamic Acids; Hypokalemia; Levodopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease; Penicillins; Probenecid; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1985
Lyme disease. Clinical evidence, 2002, Issue:8 Topics: Adolescent; Adult; Aged; Amoxicillin; Animals; Bacterial Vaccines; Bites and Stings; Borrelia burgdorferi; Ceftriaxone; Doxycycline; Humans; Lyme Disease; Lyme Neuroborreliosis; Middle Aged; Penicillins; Probenecid; Ticks	2002
Syphilis in the HIV-infected patient: an update on epidemiology, diagnosis, and management. Current HIV/AIDS reports, 2004, Volume: 1, Issue:3 Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Amoxicillin; Clinical Trials as Topic; Cross-Sectional Studies; Doxycycline; Drug Therapy, Combination; Humans; Incidence; Injections, Intramuscular; Neurosyphilis; Penicillin G Benzathine; Practice Guidelines as Topic; Probenecid; Syphilis; Syphilis, Cutaneous; Syphilis, Latent; Treatment Outcome	2004
Antibiotics for treating gonorrhoea in pregnancy. The Cochrane database of systematic reviews, 2018, 02-21, Volume: 2 Topics: Amoxicillin; Anti-Bacterial Agents; Cefixime; Ceftriaxone; Female; Gonorrhea; Humans; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Randomized Controlled Trials as Topic; Spectinomycin	2018
Successive complications after anterior cervical fixation: pharyngoesophageal diverticulum, fistulization, and cervical spondylitis by Streptococcus milleri - case report and literature review. Journal of medical case reports, 2019, Apr-30, Volume: 13, Issue:1 Topics: Adjuvants, Pharmaceutic; Amoxicillin; Bone Plates; Bone Screws; Deglutition Disorders; Device Removal; Diverticulitis; Female; Humans; Middle Aged; Myotomy; Postoperative Complications; Probenecid; Radiography; Spinal Fusion; Spondylitis; Streptococcal Infections; Streptococcus milleri Group; Treatment Outcome	2019
Addition of probenecid to oral β-lactam antibiotics: a systematic review and meta-analysis. The Journal of antimicrobial chemotherapy, 2022, 08-25, Volume: 77, Issue:9 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Gonorrhea; Humans; Monobactams; Probenecid	2022

Trials

29 trial(s) available for probenecid and amoxicillin

Article	Year
A double trial of amoxycillin in the treatment of gonorrhoea. The British journal of venereal diseases, 1977, Volume: 53, Issue:2 Topics: Amoxicillin; Ampicillin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Probenecid	1977
Double-blind trial of amoxycillin and ampicillin plus probenecid in the treatment of gonorrhoea in men. The British journal of venereal diseases, 1979, Volume: 55, Issue:5 Topics: Adolescent; Adult; Aged; Amoxicillin; Ampicillin; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Gonorrhea; Humans; Male; Middle Aged; Probenecid; Random Allocation; Urethritis	1979
Clinicopharmacological evaluation of amoxicillin and probenecid against bacterial meningitis. Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:3 Topics: Amoxicillin; Ampicillin; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Meningitis; Probenecid; Time Factors	1979
Otosyphilis: a diagnostic and therapeutic dilemma. The Laryngoscope, 1992, Volume: 102, Issue:11 Topics: Adult; Aged; Amoxicillin; Cardiolipins; Cerebrospinal Fluid; Cholesterol; Clinical Protocols; Cochlear Diseases; Decision Trees; Drug Therapy, Combination; Female; Fluorescent Treponemal Antibody-Absorption Test; Hearing Tests; Humans; Male; Middle Aged; New York City; Penicillin G; Phosphatidylcholines; Prednisone; Probenecid; Syphilis; Vestibular Diseases	1992
Treatment of early Lyme disease. The American journal of medicine, 1992, Volume: 92, Issue:4 Topics: Adult; Amoxicillin; Antibodies, Bacterial; Azithromycin; Borrelia burgdorferi Group; Doxycycline; Erythema Chronicum Migrans; Erythromycin; Female; Follow-Up Studies; Humans; Immunoglobulin G; Immunoglobulin M; Lyme Disease; Male; Middle Aged; Nervous System Diseases; Pilot Projects; Probenecid; Sensation; Treatment Outcome	1992
Amoxycillin, syphilis, and HIV infection. Lancet (London, England), 1990, Feb-24, Volume: 335, Issue:8687 Topics: Amoxicillin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; HIV Seropositivity; Humans; Probenecid; Syphilis	1990
Amoxycillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis. Lancet (London, England), 1990, Dec-08, Volume: 336, Issue:8728 Topics: Adult; Amoxicillin; Doxycycline; Drug Therapy, Combination; Female; Humans; Lyme Disease; Male; Probenecid; Prospective Studies	1990
Single-dose oral cefixime versus amoxicillin plus probenecid for the treatment of uncomplicated gonorrhea in men. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:2 Topics: Adolescent; Adult; Amoxicillin; Cefixime; Cefotaxime; Gonorrhea; Humans; Male; Probenecid; Randomized Controlled Trials as Topic; Urethritis	1990
Efficacy of ceftizoxime in the treatment of uncomplicated gonorrhoea: comparison with amoxycillin. The British journal of clinical practice, 1990, Volume: 44, Issue:6 Topics: Adolescent; Adult; Amoxicillin; Ceftizoxime; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Middle Aged; Probenecid	1990
The use of probenecid to increase the serum amoxycillin levels in patients with bronchiectasis. Respiratory medicine, 1990, Volume: 84, Issue:2 Topics: Adult; Aged; Amoxicillin; Bronchiectasis; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Probenecid	1990
Ciprofloxacin versus amoxycillin and probenecid in the treatment of uncomplicated gonorrhoea. Scandinavian journal of infectious diseases. Supplementum, 1989, Volume: 60 Topics: Adolescent; Adult; Amoxicillin; Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Drug Combinations; Female; Follow-Up Studies; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neisseria gonorrhoeae; Probenecid; Random Allocation	1989
Single-dose efficacy of ofloxacin in uncomplicated gonorrhea. The American journal of medicine, 1989, Dec-29, Volume: 87, Issue:6C Topics: Adolescent; Adult; Amoxicillin; Ampicillin Resistance; Drug Combinations; Drug Resistance, Microbial; Female; Gonorrhea; Humans; Male; Middle Aged; Multicenter Studies as Topic; Neisseria gonorrhoeae; Ofloxacin; Probenecid; Random Allocation	1989
Pharmacokinetic comparison of two models of endocarditis prophylaxis with amoxycillin. Scandinavian journal of infectious diseases, 1989, Volume: 21, Issue:6 Topics: Adult; Amoxicillin; Dose-Response Relationship, Drug; Drug Combinations; Endocarditis, Bacterial; Female; Humans; Male; Middle Aged; Models, Biological; Probenecid; Streptococcal Infections	1989
Multicenter randomized study of single-dose ofloxacin versus amoxicillin-probenecid for treatment of uncomplicated gonococcal infection. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:2 Topics: Adult; Amoxicillin; Chlamydia Infections; Chlamydia trachomatis; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Probenecid; Random Allocation	1989
Clinical comparison of single-oral-dose cefuroxime axetil and amoxicillin with probenecid for uncomplicated gonococcal infections in women. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6 Topics: Adolescent; Adult; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonorrhea; Humans; Middle Aged; Probenecid	1989
Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections. Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2 Topics: Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Probenecid; Prospective Studies; Random Allocation	1986
Comparison of oral treatment of uncomplicated urogenital and rectal gonorrhoea with cefuroxime axetil ester or clavulanic acid potentiated amoxycillin (Augmentin). Genitourinary medicine, 1986, Volume: 62, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefuroxime; Cephalosporins; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Middle Aged; Probenecid; Random Allocation	1986
[Amoxicillin in the treatment of gonorrhea. A reevaluation of the national guidelines]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1986, Oct-30, Volume: 106, Issue:30 Topics: Amoxicillin; Clinical Trials as Topic; Female; Gonorrhea; Humans; Legislation, Medical; Male; Norway; Probenecid	1986
Cefuroxime axetil for treatment of uncomplicated gonorrhea. Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2 Topics: Adolescent; Adult; Aged; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Gonorrhea; Humans; Male; Middle Aged; Probenecid; Random Allocation; Rectal Diseases; Urethritis	1986
Augmentin compared with amoxycillin in treating uncomplicated gonorrhoea. Genitourinary medicine, 1985, Volume: 61, Issue:3 Topics: Amoxicillin; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillinase; Probenecid; Random Allocation	1985
Comparison between bacampicillin and amoxycillin in treating genital and extragenital infection with Neisseria gonorrhoeae and pharyngeal infection with Neisseria meningitidis. The British journal of venereal diseases, 1984, Volume: 60, Issue:6 Topics: Amoxicillin; Ampicillin; Anus Diseases; Bacterial Infections; Drug Therapy, Combination; Female; Genital Diseases, Female; Genital Diseases, Male; Gonorrhea; Humans; Male; Neisseria meningitidis; Pharyngeal Diseases; Probenecid; Random Allocation; Rectal Diseases	1984
Amoxycillin/clavulanic acid: the effect of probenecid. The Journal of antimicrobial chemotherapy, 1983, Volume: 12, Issue:3 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acids; Drug Combinations; Drug Interactions; Humans; Probenecid	1983
Treatment of Lyme arthritis. Arthritis and rheumatism, 1994, Volume: 37, Issue:6 Topics: Adolescent; Adult; Aged; Amoxicillin; Ceftriaxone; Doxycycline; Drug Therapy, Combination; Female; Follow-Up Studies; HLA-DR Antigens; Humans; Injections, Intravenous; Lyme Disease; Male; Middle Aged; Probenecid; Treatment Outcome	1994
Treatment of gonorrhea in pregnancy. Obstetrics and gynecology, 1993, Volume: 81, Issue:1 Topics: Adult; Amoxicillin; Ceftriaxone; Drug Therapy, Combination; Female; Gonorrhea; Humans; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Prospective Studies; Spectinomycin	1993
A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency virus infection. The Syphilis and HIV Study Group. The New England journal of medicine, 1997, Jul-31, Volume: 337, Issue:5 Topics: Adult; Amoxicillin; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Penicillin G Benzathine; Penicillins; Probenecid; Syphilis; Syphilis Serodiagnosis; Treatment Failure; Treponema pallidum	1997
Treponemal specific tests for the serodiagnosis of syphilis. Syphilis and HIV Study Group. Sexually transmitted diseases, 1998, Volume: 25, Issue:10 Topics: Amoxicillin; Antibodies, Bacterial; Cohort Studies; Drug Therapy, Combination; Female; Fluorescent Treponemal Antibody-Absorption Test; Follow-Up Studies; Hemagglutination Tests; Humans; Male; Penicillin G Benzathine; Penicillins; Probenecid; Prospective Studies; Reproducibility of Results; Sensitivity and Specificity; Syphilis; Syphilis Serodiagnosis; Treponema pallidum; United States; Uricosuric Agents	1998
Comparison of oral cefixime and intravenous ceftriaxone followed by oral amoxicillin in disseminated Lyme borreliosis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, Volume: 17, Issue:10 Topics: Administration, Oral; Adult; Amoxicillin; Cefixime; Cefotaxime; Ceftriaxone; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intravenous; Lyme Disease; Penicillins; Probenecid; Renal Agents; Treatment Outcome	1998
The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:1 Topics: Acetamides; Adolescent; Adult; Amoxicillin; Animals; Antiviral Agents; Biological Transport; CHO Cells; Cimetidine; Cricetinae; Cross-Over Studies; Drug Interactions; Female; Humans; Influenza, Human; Kidney; Male; Middle Aged; Neuraminidase; Organic Anion Transport Protein 1; Oseltamivir; p-Aminohippuric Acid; Probenecid; Prodrugs	2002
Combination of Amoxicillin 3000 mg and Probenecid Versus 1500 mg Amoxicillin Monotherapy for Treating Syphilis in Patients With Human Immunodeficiency Virus: An Open-Label, Randomized, Controlled, Non-Inferiority Trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 09-11, Volume: 77, Issue:5 Topics: Amoxicillin; Anti-Bacterial Agents; Drug-Related Side Effects and Adverse Reactions; HIV; HIV Infections; Humans; Penicillin G Benzathine; Probenecid; Syphilis	2023

Other Studies

46 other study(ies) available for probenecid and amoxicillin

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Recommended treatment schedules for gonorrhea--1979. Archives of dermatology, 1979, Volume: 115, Issue:8 Topics: Acute Disease; Adult; Amoxicillin; Ampicillin; Child; Drug Administration Schedule; Epididymitis; Female; Gonorrhea; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Ophthalmia Neonatorum; Penicillin G Procaine; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Salpingitis; Tetracycline	1979
Clinical pharmacological studies of amoxycillin: effect of probenecid. The British journal of venereal diseases, 1979, Volume: 55, Issue:3 Topics: Adult; Amoxicillin; Ampicillin; Biological Availability; Drug Synergism; Humans; Probenecid; Time Factors	1979
Curing of typhoid carriers by cholecystectomy combined with amoxycillin plus probenecid treatment. Chemotherapy, 1979, Volume: 25, Issue:6 Topics: Adult; Aged; Amoxicillin; Carrier State; Cholecystectomy; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Probenecid; Typhus, Epidemic Louse-Borne	1979
[A single oral dose of amoxicillin with probenecid in treatment of uncomplicated gonorrhea]. Duodecim; laaketieteellinen aikakauskirja, 1979, Volume: 95, Issue:22 Topics: Adult; Amoxicillin; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Probenecid	1979
Amoxycillin in male urethral gonorrhoea. The Medical journal of Australia, 1977, Dec-03, Volume: 2, Issue:23 Topics: Amoxicillin; Ampicillin; Drug Therapy, Combination; Gonorrhea; Humans; Male; Probenecid; Urethral Diseases	1977
[Oral treatment of uncomplicated, urogenital and/or rectal gonorrhea with amoxicillin and probenecid]. Nederlands tijdschrift voor geneeskunde, 1978, Mar-25, Volume: 122, Issue:12 Topics: Administration, Oral; Amoxicillin; Ampicillin; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Probenecid; Proctitis; Recurrence; Urethritis; Vaginitis	1978
Gonorrhea in preschool- and school-aged children. Report of the prepubertal gonorrhea cooperative study group. JAMA, 1976, Sep-20, Volume: 236, Issue:12 Topics: Administration, Oral; Adolescent; Age Factors; Amoxicillin; Ampicillin; Child; Child, Preschool; Costa Rica; Female; Follow-Up Studies; Gonorrhea; Humans; Infant; Injections, Intramuscular; Male; Penicillin G Procaine; Probenecid; Texas; United States	1976
The choice of antibiotic for treating infective endocarditis. The Quarterly journal of medicine, 1975, Volume: 44, Issue:175 Topics: Adolescent; Adult; Aged; Amoxicillin; Amphotericin B; Aneurysm, Infected; Anti-Bacterial Agents; Bacteria; Cardiac Surgical Procedures; Child; Cloxacillin; Endocarditis; Endocarditis, Bacterial; Erythromycin; Fusidic Acid; Gentamicins; Humans; Kanamycin; Middle Aged; Probenecid; Renal Dialysis; Staphylococcal Infections	1975
The diagnosis and treatment of Lyme disease. Kansas medicine : the journal of the Kansas Medical Society, 1992, Volume: 93, Issue:9 Topics: Amoxicillin; Ceftriaxone; Humans; Lyme Disease; Probenecid	1992
Failure of Borrelia burgdorferi to survive in the skin of patients with antibiotic-treated Lyme disease. Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:1 Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Borrelia burgdorferi Group; Doxycycline; Erythema Multiforme; Female; Humans; Lyme Disease; Male; Middle Aged; Probenecid; Skin; Time Factors	1992
Clinical experience in the use of clavulanic acid/penicillin regimens in the treatment of uncomplicated gonorrhoea. Annals of the Academy of Medicine, Singapore, 1986, Volume: 15, Issue:2 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acids; Drug Combinations; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin G; Penicillin Resistance; Probenecid	1986
[Amoxicillin in the treatment of gonorrhea]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1988, Oct-10, Volume: 108, Issue:28 Topics: Acute Disease; Amoxicillin; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Probenecid	1988
Clavulanate-potentiated amoxycillin: in vitro antibacterial activity and oral bioavailability in calves. Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:2 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Biological Availability; Cattle; Clavulanic Acids; Drug Combinations; Drug Synergism; Escherichia coli; Kinetics; Male; Microbial Sensitivity Tests; Pasteurella; Probenecid; Salmonella	1987
Three regimens of procaine penicillin G, Augmentin, and probenecid compared for treating acute gonorrhoea in men. Genitourinary medicine, 1986, Volume: 62, Issue:2 Topics: Acute Disease; Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acids; Drug Combinations; Gonorrhea; Humans; Injections, Intramuscular; Male; Penicillin G; Penicillin G Procaine; Probenecid	1986
Oral amoxycillin, an alternative treatment for neurosyphilis. Genitourinary medicine, 1985, Volume: 61, Issue:6 Topics: Administration, Oral; Amoxicillin; Animals; Disease Models, Animal; Female; Humans; Male; Neurosyphilis; Probenecid; Rabbits; Treponema pallidum	1985
Failure of a single dose amoxycillin as prophylaxis against endocarditis. British medical journal (Clinical research ed.), 1985, Mar-02, Volume: 290, Issue:6469 Topics: Amoxicillin; Drug Therapy, Combination; Endocarditis, Bacterial; Humans; Probenecid	1985
Single dose oral amoxycillin 3 g with either 125 mg or 250 mg clavulanic acid to treat uncomplicated anogenital gonorrhoea. Genitourinary medicine, 1985, Volume: 61, Issue:3 Topics: Administration, Oral; Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Female; Gonorrhea; Humans; Male; Probenecid	1985
A controlled trial of amoxycillin in 104 male patients with gonorrhoea. The Medical journal of Australia, 1974, Dec-14, Volume: 2, Issue:24 Topics: Adolescent; Adult; Age Factors; Amoxicillin; Ampicillin; Child; Coitus; Drug Combinations; Follow-Up Studies; Gonorrhea; Humans; Male; Middle Aged; Penicillin G Procaine; Penicillins; Probenecid; Time Factors	1974
The penicillins. Mayo Clinic proceedings, 1983, Volume: 58, Issue:1 Topics: Amoxicillin; Ampicillin; Bacterial Infections; Carbenicillin; Drug Administration Schedule; Drug Evaluation; Drug Hypersensitivity; Drug Synergism; Humans; Penicillin G; Penicillins; Piperacillin; Probenecid; Ticarcillin	1983
Gonorrhoea in a Sydney house of prostitution. The Medical journal of Australia, 1984, Mar-03, Volume: 140, Issue:5 Topics: Adolescent; Adult; Amoxicillin; Australia; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Physical Examination; Probenecid; Sex Work	1984
The effect of probenecid on serum amoxycillin concentrations up to 18 hours after a single 3 g oral dose of amoxycillin: possible implications for preventing endocarditis. The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:6 Topics: Administration, Oral; Adult; Amoxicillin; Drug Interactions; Drug Therapy, Combination; Endocarditis, Bacterial; Humans; Kinetics; Male; Probenecid	1984
Parenteral augmentin: pharmacokinetics. International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:8 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Female; Half-Life; Humans; Hypoglycemic Agents; Infusions, Parenteral; Injections, Intravenous; Kinetics; Male; Probenecid	1984
Management of infective endocarditis. Journal of the Royal College of Physicians of London, 1981, Volume: 15, Issue:3 Topics: Amoxicillin; Endocarditis; Humans; Penicillins; Postoperative Complications; Probenecid; Serologic Tests	1981
Serum and subcutaneous chamber fluid dynamics of penicillins after single large parenteral doses. Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:2 Topics: Amoxicillin; Animals; Body Fluids; Drug Implants; Injections; Injections, Intramuscular; Male; Penicillin G; Penicillins; Probenecid; Rabbits; Skin	1980
Effect of probenecid on amoxycillin. The British journal of venereal diseases, 1980, Volume: 56, Issue:3 Topics: Amoxicillin; Drug Synergism; Female; Humans; Male; Probenecid; Salpingitis	1980
The intestinal elimination of ciprofloxacin in the rat. The Journal of infectious diseases, 1994, Volume: 169, Issue:1 Topics: Amoxicillin; Analysis of Variance; Animals; Biological Transport; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Ileum; Jejunum; Male; Nifedipine; Probenecid; Rats; Rats, Sprague-Dawley	1994
Non-culture Neisseria gonorrhoeae molecular penicillinase production surveillance demonstrates the long-term success of empirical dual therapy and informs gonorrhoea management guidelines in a highly endemic setting. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:5 Topics: Administration, Oral; Amoxicillin; Azithromycin; Drug Therapy, Combination; Epidemiological Monitoring; Gonorrhea; Humans; Neisseria gonorrhoeae; Penicillinase; Plasmids; Probenecid; Western Australia	2014
High-dose oral amoxicillin plus probenecid is highly effective for syphilis in patients with HIV infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Jul-15, Volume: 61, Issue:2 Topics: Administration, Oral; Adult; Amoxicillin; Anti-Bacterial Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; Humans; Male; Probenecid; Retrospective Studies; Risk Factors; Syphilis; Syphilis Serodiagnosis; Treatment Outcome; Young Adult	2015
Australian Gonococcal Surveillance Programme, 1 July to 30 September 2015. Communicable diseases intelligence quarterly report, 2016, Mar-31, Volume: 40, Issue:1 Topics: Amoxicillin; Anti-Bacterial Agents; Australia; Azithromycin; Ceftriaxone; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillins; Probenecid; Public Health Surveillance	2016
[A case of early syphilitic hepatitis with jaundice cured by high-dose amoxicillin and probenecid]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2021, Volume: 118, Issue:2 Topics: Adult; Amoxicillin; Hepatitis; Humans; Jaundice; Male; Probenecid; Syphilis	2021
Clinical efficacy and tolerability of 1.5 g/day oral amoxicillin therapy without probenecid for the treatment of syphilis. Sexually transmitted infections, 2022, Volume: 98, Issue:3 Topics: Amoxicillin; Anti-Bacterial Agents; HIV Infections; Humans; Probenecid; Retrospective Studies; Syphilis; Syphilis Serodiagnosis; Treatment Outcome; Treponema pallidum	2022