Page last updated: 2024-08-16

probenecid and allopurinol

probenecid has been researched along with allopurinol in 193 studies

Research

Studies (193)

Timeframe	Studies, this research(%)	All Research%
pre-1990	111 (57.51)	18.7374
1990's	11 (5.70)	18.2507
2000's	22 (11.40)	29.6817
2010's	45 (23.32)	24.3611
2020's	4 (2.07)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Fu, P; Li, X; Liu, J; Ma, L	1
Musil, J	1
Boss, GR; Seegmiller, JE	1
Gancitano, A; Pallalardo, A	1
Kleinschmidt, A; Schräpler, P; Schulz, E	1
Emmerson, BT	1
Bolli, P; Simpson, FO; Waal-Manning, HJ; Wood, AJ	1
Christensen, LK; Hansen, JM	1
Simkin, PA	1
Gibson, T; Horner, I; Kilbourn, K; Simmonds, HA	1
McCarty, DJ	1
Talbott, JH	1
Cacini, W; Quebbemann, AJ	1
Gordon, GV; Schumacher, HR	1
Fanelli, GM; Weiner, IM	2
Mikanagi, K; Nishioka, K	2
Alvsaker, JO	1
Brzozowska, AM; Eyman, E; Kawenoki-Minc, E; Weryńska-Przybylska, J	1
Nishioka, K	1
Horwitz, D; Mitchell, JR; Thorgeirsson, SS	1
Lowenthal, DT	1
Kelley, WN	2
Schräpler, P; Schulz, E	1
Nicholson, G	1
Brzozowska, M; Eyman, E; Kawenoki-Minc, E; Leo, W; Weryńska-Przybylska, J	1
Naess, K	1
Iimura, O; Nakata, T	1
Barthelemy, CR; McCarthy, GM; Veum, JA; Wortmann, RL	1
Shinosaki, T; Yonetani, Y	1
Cathey, MA; Wolfe, F	1
Hada, T; Higashino, K; Suda, M; Takahashi, S; Yamamoto, T	1
Johnson, CM; Marr, JJ; Nelson, DJ; Pattishall, KH; Paz, HM; Rogers, MD; Saenz, RE	1
Carmichael, JM; Zell, SC	1
Bontoux, D	1
Cabo, J; Gomez-Ruiz, MD; Izquierdo, R; Rodilla, F; Sanchez-Beltran, MJ	2
Smith, CR	1
German, DC; Holmes, EW	1
Kawenoki-Minc, E	2
Darlington, LG; Scott, JT	1
Schlapbach, P	1
Lo, B	1
Elion, GB	1
Zöllner, N	1
Gutman, AB	3
Ball, GV; Freeman, D	1
Krebs, A; Zürcher, K	1
Gibson, T; Grahame, R	1
Cucinell, SA; Dayton, PG; Gutman, AB; Israili, ZH; Perel, JM; Tjandramaga, TB; Yü, TF	1
Yü, T; Yu, TF	1
Fabre, J; Herrera, A; Perrin, L; Petitpierre, B; Rudhardt, M	1
Kawenoki-Minc, E; Zieliński, Z	1
Quebbemann, AJ	1
Ignarro, LJ	1
Bluestone, R; Campion, D; Klinenberg, JR; Whitehouse, M	1
Gutman, AB; Yü, TF	1
Mayr, E	1
Hvidberg, E	1
Goldfinger, SE	1
Gottesbüren, H; Strohmeyer, G	1
Kelley, WN; Wyngaarden, JB	1
Kolassa, N; Pfleger, K; Volkmer, I	1
McMahon, FG	1
Fabre, J; Perrin, L; Petitpierre, B; Rudhardt, M	1
Dörner, K; Harms, D; Manzke, H	1
Ina, K; Ito, M; Suzuki, Y; Yamagami, I	1
Fujii, T; Homma, M; Kawai, T; Kishi, H; Koide, O	1
Scott, JT	1
Curzon, G; Green, AR	1
Bluestone, R; Kippen, I; Klinenberg, JR	1
Bluestone, R; Kippen, I; Klinenberg, JR; Whitehouse, M	1
Bluestone, R; Kippen, I; Klinenberg, JR; Whitehouse, MW	1
Yu, TF	1
Eyman, E; Kawenoki-Minc, E; Sopata, I; Weryńska-Przybylska, J	1
Lhoda, F	1
Moeller, HC	1
Sabah, D	1
Bluestone, R; Lewis, B; Mervart, I	1
Elion, GB; Gutman, AB; Hitchings, GH; Yü, TF	1
Riccitelli, ML	1
Highton, TC; Palmer, DG	1
Griendl, W; Kalb, R; Klein, G	1
Koch, G; Schlosser, GA	1
Holländer, E; Schwarczmann, P	1
Seegmiller, JE	1
Mikkelsen, WM; Strottman, MP; Thompson, GR	1
Bartels, EC	1
Sjöberg, KH	1
Binder, E; Otto, W	1
Michener, WM	1
Jakovcic, S; Sorensen, LB	1
Gaines, LM	1
Kaplan, NM	1
Champion, GD; Day, RO; Graham, GG; Lee, E	1
Simkin, PA; Wisner, DE	1
Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF	1
Rodnan, GP	1
Schepers, GW	1
Crisp, AJ; Grahame, R; Helliwell, M	1
Baiatova, KV	1
Hale, WE; Marks, RG; Stewart, RB; Yost, RL	1
Bollet, AJ	1
Day, RO	1
Akaoka, I; Fujimori, S; Kaneko, K; Yamanaka, H	1
Conaghan, PG; Day, RO	1
Emery, B; Hahn, B; Kaliner, MA; Ohkubo, K; Peden, DB; Swiersz, M	1
Shapiro, TA; Were, JB	1
Goriki, K; Ochiai, M; Okusaki, K; Takahashi, H; Toda, K; Tokunou, H; Uehara, S	1
Hirai, A; Saito, Y	1
Chazerain, P; Ziza, JM	1
Gröbner, W; Walter-Sack, I	1
Yamanaka, H	1
HALL, AP; HOLLOWAY, VP; SCOTT, JT	1
GOLDFINGER, S; KLINENBERG, JR; SEEGMILLER, JE	1
Pea, F	1
Choy, G	1
Moreland, LW	1
Belch, JJ; Carr, E; Davies, J; George, J; Struthers, A	1
Brouwers, JR; Houtman, PM; Jansen, TL; Reinders, MK; van Roon, EN	1
Burhenne, J; Göggelmann, C; Haefeli, WE; Mikus, G; Rengelshausen, J; Riedel, KD; Walter-Sack, I	1
Avorn, J; Brookhart, MA; Levin, R; Solomon, DH	1
Day, RO; Graham, GG; McLachlan, AJ; Stocker, SL; Williams, KM	2
Brouwers, JR; Delsing, J; Griep, EN; Hoekstra, M; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN	1
Asch, SM; Hodges, JS; Singh, JA	1
Andrade, SE; Briesacher, BA; Fouayzi, H; Harrold, LR; Ockene, IS; Raebel, MA; Yood, RA	1
Schlesinger, N; Thiele, RG	1
Ali, S; Lally, EV	1
Simon, HB	1
Julkunen, H; Konttinen, YT	1
Quillen, DM	1
Taniguchi, A	1
Crittenden, DB; Fisher, MC; Goldfarb, DS; Keenan, RT; Krasnokutsky, S; Lee, KH; O'Brien, WR; Oh, C; Pillinger, MH	1
Kriegsmann, J; Lange, U; Müller-Ladner, U; Panzner, I; Tausche, AK	1
Frezzatti, R; Silveira, PF	1
Brett, J; Day, R; Kerridge, I; Lipworth, W	1
Curiel, RV; Guzman, NJ	1
Asmahan, MI; Hilmi, BA; Rosman, A	1
Carey, JJ; Conway, R; Coughlan, RJ	1
Feig, DI; Soletsky, B	1
Bach, MH; Simkin, PA	1
Wang, HH; Xiang, GD	1
Bardin, T; Doherty, M; Jansen, TL; Nuki, G; Pascual, E; Perez-Ruiz, F; Punzi, L; Richette, P; So, AK	1
Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R	2
Dalbeth, N; Robinson, PC	1
Fitzgerald, KA; Gyongyosi, B; Iracheta-Vellve, A; Kodys, K; Kurt-Jones, EA; Petrasek, J; Saha, B; Satishchandran, A; Szabo, G	1
Dalbeth, N; Stamp, L	1
Stamp, LK	1
Borgi, L; Curhan, GC; Fisher, ND; Forman, JP; McMullan, C; Wohlhueter, A	1
Aviña-Zubieta, JA; Choi, HK; De Vera, MA; McCormick, N; Rai, SK; Sayre, EC; Shojania, K	1
Corbett, EJM; McGill, NW; Pentony, P	1
Borgi, L; Curhan, G; Fisher, N; Forman, J; McMullan, CJ	1
Chaiyakunapruk, N; Chong, HY; Lim, YH; Mohamed, Z; Prawjaeng, J; Tassaneeyakul, W	1
Givertz, MM	1
Desai, RJ; Kang, EH; Kim, SC; Liu, J; Neogi, T; Solomon, DH; Zhang, M	1
Cheetham, TC; Levy, G; Rashid, N; Shi, JM	1
Jansen, TL; Perez-Ruiz, F; Richette, P; Tausche, AK	1
Robinson, PC	1
Chen-Xu, M; Choi, HK; Pillinger, MH; Rai, SK; Yokose, C	1
Deng, X; Li, J; Liu, H; Qi, Y; Xiong, B; Zhang, Y	1
Kang, EH; Kim, SC	1
Cheung, PP; Chua, CKT; Lim, AYN; Santosa, A; Teng, GG	1
Dai, S; Guo, Y; Hong, F; Li, L; Liu, G; Pan, S; Qiao, X; Wang, J; Xie, X; Xu, P; Xue, T; Zhai, Y; Zheng, A	1
Desai, RJ; Kim, E; Kim, SC; Lii, J; Neogi, T	1
Borghi, C; Cicero, AFG; Fogacci, F; Kuwabara, M	1

Reviews

42 review(s) available for probenecid and allopurinol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pharmacological urate-lowering approaches in chronic kidney disease. European journal of medicinal chemistry, 2019, Mar-15, Volume: 166 Topics: Biological Products; Drug Discovery; Flavonoids; Humans; Renal Insufficiency, Chronic; Uric Acid	2019
Hyperuricemia and gout. Classification, complications and management. The New England journal of medicine, 1979, Jun-28, Volume: 300, Issue:26 Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Indomethacin; Kidney; Kidney Calculi; Kidney Diseases; Lead Poisoning; Lymphoproliferative Disorders; Myeloproliferative Disorders; Phenylbutazone; Platelet Aggregation; Probenecid; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrazinamide; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Uricosuric Agents	1979
[Gout. Diagnosis--pathogenesis--therapy]. Fortschritte der Medizin, 1978, Mar-30, Volume: 96, Issue:12 Topics: Allopurinol; Balneology; Benzofurans; Crystallization; Diagnosis, Differential; Exercise Therapy; Glomerular Filtration Rate; Gout; Probenecid; Sulfinpyrazone; Uric Acid; Urinary Calculi	1978
Drug control of gout and hyperuricaemia. Drugs, 1978, Volume: 16, Issue:2 Topics: Allopurinol; Arthritis; Chronic Disease; Colchicine; Gout; Humans; Indomethacin; Naproxen; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1978
Drug interactions with oral sulphonylurea hypoglycaemic drugs. Drugs, 1977, Volume: 13, Issue:1 Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide	1977
Pharmacologic approach to the maintenance of urate homeostasis. Nephron, 1975, Volume: 14, Issue:1 Topics: Allopurinol; Diuresis; Gout; Homeostasis; Humans; Kidney Tubules; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents; Xanthine Oxidase	1975
Hyperuricemia and gout. The Medical clinics of North America, 1986, Volume: 70, Issue:2 Topics: Acute Disease; Adult; Allopurinol; Anti-Inflammatory Agents; Arthritis; Arthrography; Calcinosis; Chronic Disease; Colchicine; Female; Gout; Humans; Kidney Calculi; Kidney Diseases; Middle Aged; Probenecid; Uric Acid	1986
[Gout: diagnosis and therapy]. Therapeutische Umschau. Revue therapeutique, 1985, Volume: 42, Issue:10 Topics: Allopurinol; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Probenecid; Sulfinpyrazone	1985
Arthritis & other rheumatic diseases. I. Introduction. Quarterly medical review, 1971, Volume: 21, Issue:4 Topics: Adrenocorticotropic Hormone; Allopurinol; Analgesics; Arthritis, Juvenile; Arthritis, Rheumatoid; Colchicine; Diagnosis, Differential; Gold; Gout; Humans; Phenylbutazone; Probenecid; Prognosis; Rheumatic Diseases; Rheumatic Fever	1971
Milestones in the treatment of gout. The American journal of medicine, 1974, Volume: 56, Issue:5 Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Kidney Calculi; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1974
Principles of current management of primary gout. The American journal of the medical sciences, 1967, Volume: 254, Issue:6 Topics: Adult; Allopurinol; Diet Therapy; Female; Gout; Humans; Male; Middle Aged; Probenecid; Sulfinpyrazone	1967
[Antarthritics. 41]. Pharmazeutische Praxis, 1969, Volume: 12 Topics: Acute Disease; Allopurinol; Antineoplastic Agents; Benzofurans; Colchicine; Female; Gout; Humans; Phenylbutazone; Pregnancy; Probenecid; Sulfinpyrazone; Uricosuric Agents; Vasodilator Agents; Zoxazolamine	1969
[Drug therapy in gout]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1971, Jul-01, Volume: 24, Issue:13 Topics: Allopurinol; Chemical Phenomena; Chemistry; Colchicine; Gout; Humans; Phagocytosis; Probenecid; Purines; Uric Acid	1971
Treatment of gout. The New England journal of medicine, 1971, Dec-02, Volume: 285, Issue:23 Topics: Adrenal Cortex Hormones; Allopurinol; Colchicine; Gout; Humans; Indomethacin; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents; Xanthine Oxidase; Xanthines	1971
[What is certain in gout therapy?]. Der Internist, 1971, Volume: 12, Issue:12 Topics: Acute Disease; Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Kidney Tubules; Probenecid; Purines; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1971
Drug treatment of gout. Seminars in drug treatment, 1971, Volume: 1, Issue:2 Topics: Acute Disease; Allopurinol; Arthritis; Colchicine; Gout; Humans; Orotic Acid; Probenecid; Structure-Activity Relationship; Sulfinpyrazone; Uric Acid; Uricosuric Agents; Xanthine Oxidase	1971
Anti-rheumatic drug interactions. Clinics in rheumatic diseases, 1984, Volume: 10, Issue:2 Topics: Adrenergic beta-Antagonists; Allopurinol; Animals; Antacids; Anti-Inflammatory Agents; Anticoagulants; Cimetidine; Diuretics; Drug Combinations; Drug Interactions; Glucocorticoids; Gold; Humans; Hypoglycemic Agents; Penicillamine; Probenecid; Sulfinpyrazone; Vasodilator Agents	1984
Problems of antiarthritic therapy in the elderly. Journal of the American Geriatrics Society, 1984, Volume: 32, Issue:3 Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Chloroquine; Female; Gold; Gout; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis; Penicillamine; Probenecid	1984
Treatment of the gout and other forms of crystal-induced arthritis. Bulletin on the rheumatic diseases, 1982, Volume: 32, Issue:5 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Kidney; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1982
Risks and benefits of drugs used in the management and prevention of gout. Drug safety, 1994, Volume: 11, Issue:4 Topics: Adrenocorticotropic Hormone; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Double-Blind Method; Glucocorticoids; Gout; Gout Suppressants; Humans; Probenecid; Sulfinpyrazone	1994
[Management of hyperuricemia in diabetes]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl Topics: Allopurinol; Benzbromarone; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Humans; Insulin Resistance; Probenecid; Uric Acid; Uricosuric Agents	1997
[Drug therapy for idiopathic hyperuricemia--introduction, dose, and side effects]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1 Topics: Allopurinol; Arteriosclerosis; Benzbromarone; Enzyme Inhibitors; Gout; Humans; Hyperuricemia; Kidney Diseases; Probenecid; Prognosis; Risk; Uricosuric Agents; Urinary Calculi; Xanthine Oxidase	2003
Pharmacology of drugs for hyperuricemia. Mechanisms, kinetics and interactions. Contributions to nephrology, 2005, Volume: 147 Topics: Allopurinol; Drug Interactions; Humans; Hyperuricemia; Probenecid; Urate Oxidase	2005
An update on the treatment options for gout and calcium pyrophosphate deposition. Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:14 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Chondrocalcinosis; Colchicine; Drug Combinations; Enzyme Inhibitors; Febuxostat; Gout; Gout Suppressants; Humans; Multicenter Studies as Topic; Probenecid; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase	2005
Treatment failure gout. Medicine and health, Rhode Island, 2009, Volume: 92, Issue:11 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Probenecid; Treatment Failure; Urate Oxidase	2009
[The clinical picture of gout is changing]. Duodecim; laaketieteellinen aikakauskirja, 2010, Volume: 126, Issue:12 Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Probenecid; Risk Factors; Thiazoles; Uricosuric Agents	2010
Crystal arthropathies: recognizing and treating "the gouch". Primary care, 2010, Volume: 37, Issue:4 Topics: Allopurinol; Antimetabolites; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thiazoles; Uric Acid; Uricosuric Agents	2010
[Treatment of hyperuricemia and gout based on the guideline for the management of hyperuricemia and gout]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 136, Issue:6 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Glucocorticoids; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Metabolic Syndrome; Practice Guidelines as Topic; Probenecid; Uricosuric Agents	2010
[Gout - regardless of therapeutic options a "forgotten" disease]. Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:33 Topics: Allopurinol; Arthritis, Gouty; Benzbromarone; Combined Modality Therapy; Cytokines; Europe; Febuxostat; Gout; Gout Suppressants; Guideline Adherence; Humans; Inflammasomes; Interleukin-1; Long-Term Care; Probenecid; Signal Transduction; Thiazoles; Uric Acid	2011
Challenges associated with the management of gouty arthritis in patients with chronic kidney disease: a systematic review. Seminars in arthritis and rheumatism, 2012, Volume: 42, Issue:2 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Colchicine; Comorbidity; Contraindications; Febuxostat; Glucocorticoids; Gout Suppressants; Humans; Hyperuricemia; Polyethylene Glycols; Probenecid; PubMed; Renal Insufficiency, Chronic; Secondary Prevention; Thiazoles; Urate Oxidase	2012
Uricosuric drugs: the once and future therapy for hyperuricemia? Current opinion in rheumatology, 2014, Volume: 26, Issue:2 Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Discovery; Enzyme Inhibitors; Glucose Transport Proteins, Facilitative; Gout; Humans; Hydrochlorothiazide; Hyperuricemia; Kidney Tubules, Proximal; Neoplasm Proteins; Organic Anion Transporters; Organic Cation Transport Proteins; Probenecid; Uric Acid; Uricosuric Agents; Xanthine Oxidase	2014
Improving cardiovascular and renal outcomes in gout: what should we target? Nature reviews. Rheumatology, 2014, Volume: 10, Issue:11 Topics: Allopurinol; Cardiovascular Diseases; Colchicine; Diabetes Mellitus, Type 2; Disease Management; Gout; Gout Suppressants; Humans; Hyperuricemia; Inflammation; Metabolic Syndrome; Probenecid; Renal Insufficiency, Chronic; Treatment Outcome; Uricosuric Agents; Xanthine Oxidase	2014
Allopurinol for chronic gout. The Cochrane database of systematic reviews, 2014, Oct-14, Issue:10 Topics: Allopurinol; Benzbromarone; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Probenecid; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid	2014
Uricosuric medications for chronic gout. The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11 Topics: Adult; Aged; Allopurinol; Benzbromarone; Chronic Disease; Controlled Clinical Trials as Topic; Female; Gout; Humans; Male; Middle Aged; Probenecid; Randomized Controlled Trials as Topic; Uric Acid; Uricosuric Agents	2014
Advances in pharmacotherapy for the treatment of gout. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:4 Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzbromarone; Clinical Trials, Phase III as Topic; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Probenecid; Thiazoles; Urate Oxidase; Uric Acid	2015
Urate-lowering therapy for asymptomatic hyperuricaemia: A need for caution. Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4 Topics: Allopurinol; Asymptomatic Diseases; Drug Eruptions; Drug Hypersensitivity; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Uricosuric Agents; Urolithiasis	2017
Major unanswered questions in the clinical gout field. Current opinion in rheumatology, 2017, Volume: 29, Issue:2 Topics: Allopurinol; Benzbromarone; Colchicine; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Patient Care Planning; Probenecid; Renal Insufficiency, Chronic; Uric Acid; Uricosuric Agents	2017
International position paper on the appropriate use of uricosurics with the introduction of lesinurad. Clinical rheumatology, 2018, Volume: 37, Issue:12 Topics: Benzbromarone; Europe; Febuxostat; Gout; Humans; International Cooperation; Practice Guidelines as Topic; Probenecid; Rheumatology; Thioglycolates; Triazoles; Uricosuric Agents; Xanthine Oxidase	2018
Gout - An update of aetiology, genetics, co-morbidities and management. Maturitas, 2018, Volume: 118 Topics: Allopurinol; Chronic Disease; Comorbidity; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thioglycolates; Triazoles; Uric Acid	2018
Cardiovascular Safety of Urate Lowering Therapies. Current rheumatology reports, 2019, 07-24, Volume: 21, Issue:9 Topics: Allopurinol; Cardiovascular Diseases; Endothelium; Febuxostat; Gout; Gout Suppressants; Heart Failure; Humans; Hypertension; Hyperuricemia; Myocardial Infarction; Probenecid; Risk; Stroke; Uricosuric Agents; Xanthine Oxidase	2019
Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update. Medicina (Kaunas, Lithuania), 2021, Jan-10, Volume: 57, Issue:1 Topics: Acetamides; Allopurinol; Benzbromarone; Chronic Disease; Evidence-Based Medicine; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Naphthalenes; Nitriles; Phenylacetates; Polyethylene Glycols; Probenecid; Propionates; Pyridines; Thioglycolates; Triazoles; Urate Oxidase; Uricosuric Agents; Xanthine Oxidase	2021

Trials

19 trial(s) available for probenecid and allopurinol

Article	Year
Studies on tienilic acid in hypertensive hyperuricaemic patients in Dunedin, New Zealand. Postgraduate medical journal, 1979, Volume: 55 Suppl 3 Topics: Aged; Allopurinol; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Drug Therapy, Combination; Female; Glycolates; Humans; Hypertension; Kinetics; Male; Middle Aged; Probenecid; Sodium Chloride Symporter Inhibitors; Ticrynafen; Uric Acid	1979
Treatment of American cutaneous leishmaniasis with orally administered allopurinol riboside. The Journal of infectious diseases, 1989, Volume: 160, Issue:1 Topics: Adult; Allopurinol; Animals; Antiprotozoal Agents; Biopsy; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Leishmania braziliensis; Leishmaniasis; Male; Middle Aged; Probenecid; Ribonucleosides; Skin	1989
Observations on the disposition of probenecid in patients receiving allopurinol. Pharmacology, 1972, Volume: 8, Issue:4 Topics: Adult; Aged; Allopurinol; Animals; Blood Urea Nitrogen; Carbon Isotopes; Chromatography, Gas; Clinical Trials as Topic; Creatinine; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Liver; Male; Middle Aged; Probenecid; Proteins; Rats; Time Factors; Uric Acid; Xanthines	1972
Uricosurics and xanthine oxidase inhibitors: a single-dose assay. Current therapeutic research, clinical and experimental, 1970, Volume: 12, Issue:6 Topics: Adult; Allopurinol; Chlorothiazide; Humans; Male; Methods; Placebos; Probenecid; Uric Acid; Uricosuric Agents; Xanthine Oxidase	1970
Comparison of allopurinol and probenecid. Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6 Suppl Topics: Allopurinol; Clinical Trials as Topic; Colchicine; Enzyme Therapy; Follow-Up Studies; Gout; Humans; Liver Function Tests; Male; Probenecid; Sulfinpyrazone; Uric Acid; Xanthine Oxidase	1966
Effect of drugs on urate binding to plasma proteins. British medical journal, 1969, Dec-06, Volume: 4, Issue:5683 Topics: Adult; Allopurinol; Arthritis; Aspirin; Blood Proteins; Chromatography, DEAE-Cellulose; Colchicine; Female; Gout; Humans; Indomethacin; Male; Phenylbutazone; Probenecid; Protein Binding; Sulfinpyrazone; Uric Acid	1969
Benzbromarone therapy in hyperuricaemia; comparison with allopurinol and probenecid. The Journal of international medical research, 1981, Volume: 9, Issue:6 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Female; Humans; Male; Placebos; Probenecid; Uric Acid	1981
Effect of hypouricemic agents on serum carbohydrate-deficient transferrin in gouty patients. Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Allopurinol; Benzbromarone; Chromatography, Ion Exchange; Drug Therapy, Combination; Gout; Humans; Isoelectric Focusing; Male; Middle Aged; Oxypurinol; Probenecid; Radioimmunoassay; Transferrin	1994
Risks and benefits of drugs used in the management and prevention of gout. Drug safety, 1994, Volume: 11, Issue:4 Topics: Adrenocorticotropic Hormone; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Double-Blind Method; Glucocorticoids; Gout; Gout Suppressants; Humans; Probenecid; Sulfinpyrazone	1994
Effects of probenecid on the pharmacokinetics of allopurinol riboside. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5 Topics: Adult; Allopurinol; Antiprotozoal Agents; Drug Interactions; Half-Life; Humans; Male; Models, Biological; Probenecid; Ribonucleosides	1993
High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid. Circulation, 2006, Dec-05, Volume: 114, Issue:23 Topics: Acetylcholine; Aged; Allopurinol; Ascorbic Acid; Blood Pressure; Cardiac Output, Low; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitroprusside; Oxidative Stress; Probenecid; Regional Blood Flow; Uric Acid; Uricosuric Agents; Vasodilator Agents	2006
Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients. Clinical rheumatology, 2007, Volume: 26, Issue:9 Topics: Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout; Humans; Hyperuricemia; Male; Middle Aged; Probenecid; Uric Acid; Uricosuric Agents	2007
Reduction in non-glomerular renal clearance of the caffeine metabolite 1-methylxanthine by probenecid. International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:8 Topics: Adult; Area Under Curve; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Creatinine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Depression, Chemical; Double-Blind Method; Female; Humans; Kidney; Male; Probenecid; Renal Agents; Spectrophotometry, Ultraviolet; Xanthine Oxidase; Xanthines	2007
Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in healthy subjects. Clinical pharmacokinetics, 2008, Volume: 47, Issue:2 Topics: Adult; Allopurinol; Analysis of Variance; Area Under Curve; Chromatography, High Pressure Liquid; Creatinine; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Oxypurinol; Probenecid; Time Factors; Uric Acid	2008
Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:1 Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Hypersensitivity; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Prospective Studies; Treatment Failure; Uric Acid	2009
Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in patients with gout. The Journal of rheumatology, 2011, Volume: 38, Issue:5 Topics: Allopurinol; Drug Interactions; Drug Therapy, Combination; Gout; Gout Suppressants; Humans; Male; Middle Aged; Oxypurinol; Probenecid; Prospective Studies; Uric Acid; Uricosuric Agents	2011
Uric acid reduction rectifies prehypertension in obese adolescents. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:5 Topics: Adolescent; Allopurinol; Blood Pressure; Child; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Obesity; Prehypertension; Probenecid; Treatment Outcome; Uric Acid; Uricosuric Agents; Xanthine Oxidase	2012
Effect of Uric Acid-Lowering Agents on Endothelial Function: A Randomized, Double-Blind, Placebo-Controlled Trial. Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:2 Topics: Adult; Allopurinol; Brachial Artery; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Follow-Up Studies; Gout Suppressants; Humans; Hypertension; Male; Overweight; Probenecid; Time Factors; Treatment Outcome; Ultrasonography, Doppler; Uric Acid; Uricosuric Agents; Vasodilation	2017
Effect of Uric Acid Lowering on Renin-Angiotensin-System Activation and Ambulatory BP: A Randomized Controlled Trial. Clinical journal of the American Society of Nephrology : CJASN, 2017, May-08, Volume: 12, Issue:5 Topics: Adult; Allopurinol; Angiotensin II; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Boston; Double-Blind Method; Down-Regulation; Female; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Probenecid; Renin; Renin-Angiotensin System; Time Factors; Treatment Outcome; Uric Acid; Uricosuric Agents; Young Adult	2017

Other Studies

133 other study(ies) available for probenecid and allopurinol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Physiological characteristics of various experimental models for the study of disorders in purine metabolism. Advances in experimental medicine and biology, 1977, Volume: 76B Topics: Acidosis; Alkalosis; Allopurinol; Animals; Cholesterol; Disease Models, Animal; Diuresis; Fructose; Glycine; Gout; Hydrogen-Ion Concentration; Natriuresis; Oxonic Acid; Probenecid; Purines; Rats; Research Design; Species Specificity; Triazines; Triglycerides; Uric Acid	1977
[Physiopathological bases for a rational therapy of gout]. Minerva medica, 1978, Feb-04, Volume: 69, Issue:6 Topics: Allopurinol; Benzofurans; Gout; Humans; Life Style; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1978
Committee on the Review of Medicines. Recommendations on phenylbutazone, oxyphenbutazone, feprazone, allopurinol, colchicine, probenecid, and sulphinpyrazone. British medical journal, 1978, Jun-03, Volume: 1, Issue:6125 Topics: Adult; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Child; Colchicine; Drug Evaluation; Feprazone; Gout Suppressants; Humans; Oxyphenbutazone; Phenylbutazone; Probenecid; Sulfinpyrazone; United Kingdom	1978
Management of gout. Annals of internal medicine, 1979, Volume: 90, Issue:5 Topics: Adrenal Cortex Hormones; Allopurinol; Colchicine; Female; Gout; Humans; Indomethacin; Patient Education as Topic; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1979
Mechanism and treatment of hypertriglyceridaemia in gout. Annals of the rheumatic diseases, 1979, Volume: 38, Issue:1 Topics: Alcohol Drinking; Allopurinol; Cholesterol; Gout; Humans; Hyperlipidemias; Male; Middle Aged; Obesity; Probenecid; Triglycerides; Uric Acid	1979
The management of gout. Hospital practice, 1979, Volume: 14, Issue:9 Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Male; Oxyphenbutazone; Phenylbutazone; Probenecid; Sulfinpyrazone	1979
Treating gout: successful methods of prevention and control. Postgraduate medicine, 1978, Volume: 63, Issue:5 Topics: Acute Disease; Allopurinol; Colchicine; Gout; Humans; Probenecid	1978
The metabolism and active excretion of the hypoxanthine by the renal tubules in the chicken. The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:2 Topics: Allopurinol; Animals; Chickens; Female; Hypoxanthines; Kidney; Kidney Tubules; Oxypurinol; p-Aminohippuric Acid; Probenecid; Quinine	1978
Management of gout. American family physician, 1979, Volume: 19, Issue:1 Topics: Allopurinol; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Sulfinpyrazone	1979
Renal urate excretion in animal models. Nephron, 1975, Volume: 14, Issue:1 Topics: Allopurinol; Animals; Carboxylic Acids; Dogs; Goats; Haplorhini; Humans; Kidney; Kidney Tubules, Proximal; Male; Mersalyl; Pan troglodytes; Probenecid; Pyrazines; Uric Acid	1975
[Outline of gout therapy and selection of uric acid controlling agents]. Ryumachi. [Rheumatism], 1977, Volume: 17, Issue:2 Topics: Allopurinol; Gout; Humans; Probenecid	1977
[Drug therapy in uratic arthritis. II. Prevention of new attacks]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1977, May-30, Volume: 97, Issue:15 Topics: Allopurinol; Gout; Humans; Probenecid; Sulfinpyrazone	1977
[Comparison of effects of various therapeutic methods of the urinary system in patients with gout. Observations on 195 patients with gout]. Reumatologia, 1977, Volume: 15, Issue:2 Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Male; Middle Aged; Probenecid; Uric Acid; Urinary Tract	1977
[Quantitative treatment for the gout based on the multivariant analysis--the theory for decision of hypouricemic agent by discriminant function (author's transl)]. Ryumachi. [Rheumatism], 1977, Volume: 17, Issue:3 Topics: Adult; Aged; Allopurinol; Analysis of Variance; Drug Evaluation; Gout; Humans; Middle Aged; Models, Theoretical; Probenecid	1977
The influence of allopurinol and size of dose on the metabolism of phenylbutazone in patients with gout. European journal of clinical pharmacology, 1977, Oct-14, Volume: 12, Issue:2 Topics: Adult; Allopurinol; Dose-Response Relationship, Drug; Drug Interactions; Female; Gout; Half-Life; Humans; Male; Middle Aged; Phenylbutazone; Probenecid	1977
Drugs for gout. The Medical letter on drugs and therapeutics, 1976, Jun-04, Volume: 18, Issue:12 Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Probenecid; Sulfinpyrazone	1976
The treatment of hyperuricemia. American family physician, 1976, Volume: 14, Issue:1 Topics: Allopurinol; Drug Interactions; Drug Therapy, Combination; Humans; Phenylbutazone; Probenecid; Salicylates; Sulfinpyrazone; Uric Acid; Uricosuric Agents; Xanthine Oxidase	1976
Current therapy of gout and hyperuricemia. Hospital practice, 1976, Volume: 11, Issue:5 Topics: Allopurinol; Colchicine; Drug Interactions; Gout; Humans; Indomethacin; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1976
[Pathogenesis of hyperuricemia and its treatment by means of rigorous fasting (so-called null-diet)]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 1 Topics: Allopurinol; Fasting; Humans; Obesity; Probenecid; Uric Acid	1976
Gout: diagnosis and management. The British journal of clinical practice, 1975, Volume: 29, Issue:4 Topics: Allopurinol; Anti-Inflammatory Agents; Gout; Humans; Probenecid; Uric Acid	1975
[Effect of different therapeutic methods on the development of arthropathy in patients with gout. Observation of 155 cases]. Reumatologia, 1975, Volume: 13, Issue:4 Topics: Adult; Aged; Allopurinol; Colchicine; Gout; Humans; Joint Diseases; Middle Aged; Probenecid	1975
[Recent advances in the treatment of gout - current concept of the treatment and its theoretical background]. Ryumachi. [Rheumatism], 1975, Volume: 15, Issue:2 Topics: Allopurinol; Gout; Humans; Probenecid	1975
[Uricosuric agents: Should they be used in asymptomatic hyperuricemia?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Jan-10, Volume: 96, Issue:1 Topics: Allopurinol; Humans; Metabolic Diseases; Probenecid; Sulfinpyrazone; Uric Acid	1976
[The management of hyperuricemia associated with drug treatment of hypertension]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl Topics: Acidosis; Adrenergic beta-Antagonists; Allopurinol; Antihypertensive Agents; Benzothiadiazines; Diuretics; Humans; Probenecid; Sodium Chloride Symporter Inhibitors; Sulfinpyrazone; Uric Acid	1992
Influence of antihyperuricemic therapy on the clinical and radiographic progression of gout. Arthritis and rheumatism, 1991, Volume: 34, Issue:12 Topics: Aged; Aged, 80 and over; Allopurinol; Arthritis, Gouty; Humans; Middle Aged; Probenecid; Radiography; Uric Acid; Wrist	1991
Hyperuricemia induced by the uricosuric drug probenecid in rats. Japanese journal of pharmacology, 1991, Volume: 55, Issue:4 Topics: Allopurinol; Animals; Hepatectomy; Hypoxanthines; Inulin; Kidney Function Tests; Male; Oxonic Acid; Probenecid; Pyrazinamide; Rats; Rats, Inbred Strains; Uric Acid; Xanthines	1991
The misdiagnosis of gout and hyperuricemia. The Journal of rheumatology, 1991, Volume: 18, Issue:8 Topics: Adult; Aged; Allopurinol; Analysis of Variance; Arthritis, Psoriatic; Chondrocalcinosis; Colchicine; Databases, Factual; Diagnostic Errors; Female; Gout; Humans; Male; Middle Aged; Prevalence; Probenecid; Prospective Studies; Uremia	1991
Effect of probenecid on oxypurines in plasma. International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:10 Topics: Adenosine Deaminase; Adult; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Male; Probenecid; Purine-Nucleoside Phosphorylase; Uric Acid; Xanthine Oxidase; Xanthines	1989
Evaluation of allopurinol use in patients with gout. American journal of hospital pharmacy, 1989, Volume: 46, Issue:9 Topics: Allopurinol; Costs and Cost Analysis; Gout; Humans; Hypertension; Probenecid; Radiography; Risk Factors	1989
[Hypo-uricemia]. La Revue du praticien, 1989, Oct-11, Volume: 39, Issue:23 Topics: Allopurinol; Humans; Nucleotides; Probenecid; Urate Oxidase; Uric Acid	1989
Inhibition of purine catabolism by benzbromarone in isolated rat liver cells. Comparison with allopurinol and probenecid. Biochemical pharmacology, 1988, Oct-01, Volume: 37, Issue:19 Topics: Allopurinol; Animals; Benzbromarone; Benzofurans; In Vitro Techniques; Liver; Male; Probenecid; Purines; Rats; Rats, Inbred Strains; Uric Acid	1988
Inhibition of ureogenesis by two hypouricemic drugs (probenecid and benzbromarone). Comparison with allopurinol. Cellular and molecular biology, 1988, Volume: 34, Issue:6 Topics: Allopurinol; Animals; Arginine; Benzbromarone; In Vitro Techniques; Liver; Male; Probenecid; Rats; Rats, Inbred Strains; Urea; Uricosuric Agents	1988
Possible cardioprotective effects of allopurinol. American journal of preventive medicine, 1988, Volume: 4, Issue:2 Suppl Topics: Acute Disease; Aged; Allopurinol; Cohort Studies; Colchicine; Drug Combinations; Female; Gout; Health Maintenance Organizations; Hospital Information Systems; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Probenecid; Time Factors; Washington	1988
[Effect of decrease in hyperuricemia levels on joint, kidney and other symptoms in patients with gout]. Terapevticheskii arkhiv, 1987, Volume: 59, Issue:4 Topics: Adult; Aged; Allopurinol; Arthritis; Colchicine; Coronary Disease; Gout; Humans; Hypertension; Middle Aged; Probenecid; Uric Acid; Urinary Calculi	1987
Study of the effect of hypouricaemic therapy on serum lipid levels in gout patients. Advances in experimental medicine and biology, 1986, Volume: 195 Pt A Topics: Allopurinol; Cholesterol; Cholesterol, HDL; Gout; Humans; Lipids; Probenecid; Triglycerides; Uric Acid	1986
Hyperuricemia and gout. The Western journal of medicine, 1985, Volume: 142, Issue:1 Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Colchicine; Female; Gout; Humans; Indomethacin; Kidney Calculi; Male; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1985
Drugs in the treatment of hyperuricemia. Advances in nephrology from the Necker Hospital, 1974, Volume: 3 Topics: Allopurinol; Gout; Humans; Oxypurinol; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1974
Zyloprim and other drugs in the management of gout. The Medical letter on drugs and therapeutics, 1966, Dec-02, Volume: 8, Issue:24 Topics: Adrenocorticotropic Hormone; Colchicine; Enzyme Therapy; Enzymes; Gout; Humans; Indomethacin; Probenecid; Sulfinpyrazone; Urinary Calculi; Xanthine Oxidase	1966
[The treatment of gout and the internal medical treatment of uric acid nephrolithiasis]. Deutsche medizinische Wochenschrift (1946), 1968, Feb-16, Volume: 93, Issue:7 Topics: Adrenocorticotropic Hormone; Allopurinol; Colchicine; Gout; Humans; Indomethacin; Kidney Calculi; Prednisolone; Probenecid; Sulfinpyrazone; Uricosuric Agents	1968
Recent developments in the therapy of gout. Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:5 Topics: Acute Disease; Adrenocorticotropic Hormone; Allopurinol; Analgesics; Colchicine; Gout; Humans; Oxyphenbutazone; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1968
Management of chronic and recurrent gout. Modern treatment, 1971, Volume: 8, Issue:4 Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy; Gout; Humans; Indomethacin; Lidocaine; Phenylbutazone; Prednisolone; Probenecid; Recurrence; Synovial Fluid; Uric Acid	1971
[Cutaneous side effects of systemic drugs with special reference to recently introduced medicaments. I]. Dermatologica, 1970, Volume: 141, Issue:2 Topics: Allopurinol; Analgesics; Chlorothiazide; Colchicine; Drug Eruptions; Humans; Lichen Planus; Photosensitivity Disorders; Probenecid; Quinolines; Stevens-Johnson Syndrome; Sulfinpyrazone	1970
Gout and hyperlipidaemia. Annals of the rheumatic diseases, 1974, Volume: 33, Issue:4 Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Aspartate Aminotransferases; Body Height; Body Weight; Cholesterol; Gout; Humans; Hyperlipidemias; Liver; Male; Middle Aged; Obesity; Probenecid; Sulfobromophthalein; Triglycerides; Uric Acid	1974
Behaviour of chlorpropamide in renal insufficiency and under the effect of associated drug therapy. International journal of clinical pharmacology, therapy and toxicology, 1972, Volume: 6, Issue:2 Topics: Acenocoumarol; Allopurinol; Chloramphenicol; Chlorpropamide; Clofibrate; Glomerular Filtration Rate; Glomerulonephritis; Half-Life; Humans; Kidney; Kidney Diseases; Probenecid; Pyelonephritis	1972
Effect of balneotherapy in Ciechocinek Spa on the occurrence of gouty attacks and the symptoms of chronic gouty arthropathy (observations of 112 cures). Polish medical journal, 1972, Volume: 11, Issue:6 Topics: Adult; Aged; Allopurinol; Balneology; Blood Sedimentation; Colchicine; Female; Gout; Humans; Male; Middle Aged; Probenecid; Uric Acid	1972
Pyrazinoate excretion in the chimpanzee. Relation to urate disposition and the actions of uricosuric drugs. The Journal of clinical investigation, 1973, Volume: 52, Issue:8 Topics: Allopurinol; Aminohippuric Acids; Animals; Biological Transport; Carboxylic Acids; Chlorothiazide; Depression, Chemical; Glomerular Filtration Rate; Insulin; Iodopyracet; Kidney Tubules; Male; Organomercury Compounds; Pan troglodytes; Probenecid; Protein Binding; Pyrazines; Salicylates; Stimulation, Chemical; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1973
Renal synthesis of uric acid. The American journal of physiology, 1973, Volume: 224, Issue:6 Topics: Allopurinol; Aminohippuric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Chickens; Chromatography, Thin Layer; Diuresis; Female; Glomerular Filtration Rate; Kidney; Kidney Tubules; Models, Biological; Oxidation-Reduction; Probenecid; Quinine; Uric Acid; Xanthines	1973
Gout. British medical journal, 1974, Mar-09, Volume: 1, Issue:5905 Topics: Allopurinol; Blood Cell Count; Cell Movement; Colchicine; Diet; Drug Synergism; Gastrointestinal Diseases; Gout; Hemorrhage; Humans; Indomethacin; Leukocytes; Mercaptopurine; Phenylbutazone; Probenecid; Purines; Uric Acid	1974
Release of neutral protease and beta-glucuronidase from human neutrophils in the presence of cartilage treated with various immunologic reactants. Journal of immunology (Baltimore, Md. : 1950), 1974, Volume: 113, Issue:1 Topics: Allopurinol; Arthritis, Rheumatoid; Aspirin; Cartilage; Chloroquine; Colchicine; Factor VIII; Glucuronidase; Hot Temperature; Humans; Immunoglobulin G; Indomethacin; Iodine Radioisotopes; L-Lactate Dehydrogenase; Methylprednisolone; Neutrophils; Peptide Hydrolases; Probenecid; Protein Denaturation; Sulfur Radioisotopes; Synovial Fluid; Triamcinolone Acetonide; Vinblastine	1974
The binding of urate to plasma proteins. Advances in experimental medicine and biology, 1974, Volume: 41 Topics: Allopurinol; Aspirin; Binding Sites; Blood Proteins; Colchicine; Dialysis; Evaluation Studies as Topic; Gout; Humans; Hydrogen-Ion Concentration; Indomethacin; Kidney Diseases; Kinetics; Methods; Osmolar Concentration; Phenylbutazone; Probenecid; Protein Binding; Serum Albumin; Solubility; Sulfinpyrazone; Temperature; Time Factors; Uric Acid	1974
[Pharmacology--patient care]. Tandlaegebladet, 1971, Volume: 75, Issue:5 Topics: Allopurinol; Drug Therapy; History, 19th Century; History, 20th Century; History, Medieval; History, Modern 1601-; Humans; Kidney; Pharmacology; Pharmacopoeias as Topic; Probenecid; Uric Acid	1971
[Inhibition of adenosine uptake and stimulation of its effect on isolated hearts of warm-blooded animals by coronary active substances]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:12 Topics: Alkaloids; Allopurinol; Animals; Carbon Isotopes; Cocaine; Depression, Chemical; Dipyridamole; Drug Synergism; Ethylenediamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardium; Nitroglycerin; Nucleosides; Ouabain; Papaverine; Prenylamine; Probenecid; Pyridines; Reserpine; Stimulation, Chemical; Theophylline; Triamterene; Vasodilator Agents; Verapamil	1969
Medical management of gout. Postgraduate medicine, 1972, Volume: 51, Issue:6 Topics: Adult; Allopurinol; Colchicine; Diet Therapy; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Oxyphenbutazone; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1972
[Behavior of chlorpropamide in nephropathies in the presence of associated drugs]. Helvetica medica acta, 1972, Volume: 36, Issue:2 Topics: Allopurinol; Chloramphenicol; Chlorpropamide; Chromium Isotopes; Humans; Kidney Diseases; Probenecid	1972
[Treatment of congenital hyperuricemia]. Monatsschrift fur Kinderheilkunde, 1971, Volume: 119, Issue:7 Topics: Adolescent; Allopurinol; Athetosis; Child; Humans; Hypoxanthines; Intellectual Disability; Lesch-Nyhan Syndrome; Male; Probenecid; Purine-Pyrimidine Metabolism, Inborn Errors; Pyelonephritis; Self Mutilation; Uric Acid; Urinary Calculi; Xanthines	1971
[Pharmacological studies of diuretics. 4. Changes of serum uric acid level by the succesive administration of thiazide diuretics and other drugs and effects of uricosuric drugs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:1 Topics: Administration, Oral; Allopurinol; Ammonium Chloride; Animals; Barbiturates; Blood Glucose; Chlorothiazide; Cyclohexanes; Diuretics; Electrolytes; Ethacrynic Acid; Glycine; Hydrochlorothiazide; Hydroflumethiazide; Injections, Subcutaneous; Male; Nucleosides; Phenylbutazone; Probenecid; Quinolines; Rats; Sulfinpyrazone; Sulfonamides; Thiadiazines; Uric Acid; Uricosuric Agents; Xanthenes	1971
[A case report of von Gierke's disease with tophaceous gout]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1968, Sep-10, Volume: 57, Issue:9 Topics: Adult; Allopurinol; Glycogen Storage Disease Type I; Gout; Humans; Male; Pedigree; Probenecid	1968
Effects of immobilization on rat liver tryptophan pyrrolase and brain 5-hydroxytryptamine metabolism. British journal of pharmacology, 1969, Volume: 37, Issue:3 Topics: Adrenalectomy; Allopurinol; Animals; Brain; Brain Chemistry; Enzyme Induction; Hydroxyindoleacetic Acid; Immobilization; Liver; Lysergic Acid Diethylamide; Male; Probenecid; Rats; Serotonin; Time Factors; Tryptophan; Tryptophan Oxygenase	1969
Effect of drugs on the binding of urate to human albumin. Clinical science, 1970, Volume: 38, Issue:1 Topics: Allopurinol; Aspirin; Colchicine; Humans; Indomethacin; Phenylbutazone; Probenecid; Protein Binding; Serum Albumin; Sulfinpyrazone; Uric Acid	1970
Effect of some uricosuric and anti-inflammatory drugs on the binding of uric acid to human serum albumin in vitro. The Journal of laboratory and clinical medicine, 1970, Volume: 76, Issue:1 Topics: Allopurinol; Anti-Inflammatory Agents; Aspirin; Binding Sites; Caprylates; Colchicine; Dialysis; Fluorescence; Humans; In Vitro Techniques; Indomethacin; Mefenamic Acid; Phenylbutazone; Probenecid; Protein Binding; Serum Albumin; Sodium Salicylate; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1970
Pathogenesis and medical management of chronic gouty arthritis. Clinical orthopaedics and related research, 1970, Volume: 71 Topics: Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Joints; Kidney; Probenecid; Sulfinpyrazone; Uric Acid	1970
The influence of allopurinol on the course of gout. A study of 28 cases. Reumatologia, 1970, Volume: 8, Issue:3 Topics: Age Factors; Allopurinol; Colchicine; Drug Synergism; Gout; Humans; Probenecid; Uric Acid	1970
[Clinical aspects of gout]. Medizinische Monatsschrift, 1970, Volume: 24, Issue:4 Topics: Allopurinol; Cerebrovascular Disorders; Colchicine; Diagnosis, Differential; Diet Therapy; Female; Gout; Humans; Hypertension; Male; Probenecid; Thrombosis	1970
[Basic principles and accomplishments of the current gout therapy]. Therapie der Gegenwart, 1970, Volume: 109, Issue:11 Topics: Adult; Aged; Allopurinol; Colchicine; Diagnosis, Differential; Gout; Humans; Middle Aged; Phenylbutazone; Probenecid	1970
[Allopurinol in the treatment of gout]. Revista medica de Chile, 1970, Volume: 98, Issue:9 Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Male; Middle Aged; Probenecid; Uric Acid	1970
Hyperlipoproteinaemia in gout. Annals of the rheumatic diseases, 1971, Volume: 30, Issue:2 Topics: Adult; Aged; Allopurinol; Blood Protein Disorders; Blood Protein Electrophoresis; Cholesterol; Gout; Humans; Hyperlipidemias; Lipoproteins; Male; Middle Aged; Probenecid; Prognosis; Triglycerides; Uric Acid	1971
Renal clearance of oxipurinol, the chief metabolite of allopurinol. The American journal of medicine, 1968, Volume: 45, Issue:1 Topics: Allopurinol; Animals; Dogs; Gout; Humans; Kidney; Kidney Function Tests; Probenecid; Spectrophotometry; Uric Acid	1968
Etiology and treatment of gout--modern concepts. Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:6 Topics: Allopurinol; Colchicine; Crystallization; Diagnosis, Differential; Diet Therapy; Gout; Humans; Indomethacin; Joint Diseases; Kidney Diseases; Kidneys, Artificial; Phenylbutazone; Probenecid; Proteinuria; Purines; Radiography; Salicylates; Steroids; Sulfinpyrazone; Uric Acid	1968
A short trial assessment of uricosuric therapy in gout. Australasian annals of medicine, 1968, Volume: 17, Issue:3 Topics: Adult; Aged; Allopurinol; Female; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Probenecid; Sulfinpyrazone; Uric Acid	1968
[Allopurinol in the treatment of gout]. Zeitschrift fur Rheumaforschung, 1968, Volume: 27, Issue:11 Topics: Adult; Allopurinol; Gout; Humans; Indomethacin; Male; Middle Aged; Probenecid; Uric Acid	1968
[Therapy of gout in surgical patients]. Medizinische Klinik, 1968, Nov-22, Volume: 63, Issue:47 Topics: Achilles Tendon; Allopurinol; Cortisone; Diagnosis, Differential; Gout; Humans; Joint Diseases; Male; Middle Aged; Probenecid; Surgical Procedures, Operative; Tendinopathy; Uric Acid	1968
[Gout in advanced age]. Munchener medizinische Wochenschrift (1950), 1968, Mar-15, Volume: 110, Issue:11 Topics: Age Factors; Aged; Allopurinol; Bone and Bones; Cardiovascular Diseases; Colchicine; Female; Gout; Humans; Hyperlipidemias; Hypertension; Kidney Diseases; Male; Probenecid; Sodium; Sulfinpyrazone; Uric Acid	1968
Goals in gout. Postgraduate medicine, 1969, Volume: 45, Issue:1 Topics: Allopurinol; Colchicine; Gout; Humans; Probenecid; Sulfinpyrazone	1969
Treatment of primary gout: the present status. Arthritis and rheumatism, 1965, Volume: 8, Issue:5 Topics: Colchicine; Enzyme Therapy; Gout; Humans; Kidney Calculi; Oxyphenbutazone; Phenylbutazone; Probenecid; Uricosuric Agents; Xanthine Oxidase	1965
The effects of allopurinol on serum and urinary uric acid. Archives of internal medicine, 1966, Volume: 118, Issue:3 Topics: Adult; Aged; Blood; Enzymes; Female; Gout; Humans; Male; Probenecid; Uric Acid; Urinary Calculi; Urine; Xanthine Oxidase	1966
Allopurinol (xanthine oxidase inhibitor) in the treatment of resistant gout. JAMA, 1966, Nov-14, Volume: 198, Issue:7 Topics: Adult; Aged; Colchicine; Enzyme Therapy; Enzymes; Female; Gout; Humans; Male; Middle Aged; Probenecid; Sulfinpyrazone; Uric Acid; Xanthine Oxidase	1966
Allopurinol therapy of gout with renal complications. Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6 Suppl Topics: Adult; Allopurinol; Calcium; Creatine; Enzyme Therapy; Gout; Humans; Kidney Failure, Chronic; Male; Middle Aged; Probenecid; Uric Acid; Xanthine Oxidase	1966
[Clinical aspects of chronic gout]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, Sep-15, Volume: 21, Issue:18 Topics: Adult; Aged; Allopurinol; Anemia; Arthritis; Bicarbonates; Blood Sedimentation; Chronic Disease; Female; Gout; Humans; Joint Diseases; Male; Middle Aged; Phenylbutazone; Physical Exertion; Probenecid; Uric Acid	1966
Hyperuricemia and mental retardation with athetosis and self-mutilation. American journal of diseases of children (1960), 1967, Volume: 113, Issue:2 Topics: Allopurinol; Athetosis; Body Height; Body Weight; Child; Child, Preschool; Chorea; Humans; Infant; Intellectual Disability; Male; Probenecid; Self Mutilation; Uric Acid; Xanthine Oxidase	1967
Studies of uric acid metabolism in glycogen storage disease associated with gouty arthritis. Arthritis and rheumatism, 1967, Volume: 10, Issue:2 Topics: Adolescent; Allopurinol; Body Height; Body Weight; Carbon Isotopes; Enzyme Therapy; Glucosephosphate Dehydrogenase Deficiency; Glycine; Gout; Hepatomegaly; Humans; Male; Probenecid; Radiochemistry; Uric Acid; Xanthine Oxidase	1967
Therapy of gout. The Johns Hopkins medical journal, 1967, Volume: 121, Issue:5 Topics: Allopurinol; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Sulfinpyrazone	1967
Allupurinol and diuretic associated hyperuricaemia. Lancet (London, England), 1980, Nov-01, Volume: 2, Issue:8201 Topics: Allopurinol; Diuretics; Humans; Probenecid; Uric Acid; Uricosuric Agents	1980
Management of gout and hyperuricemia. Primary care, 1984, Volume: 11, Issue:2 Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Gout; Humans; Indomethacin; Kidney; Patient Education as Topic; Phenylbutazone; Phosphoribosyl Pyrophosphate; Probenecid; Purines; Uric Acid; Uricosuric Agents	1984
Co-existent tophaceous gout and systemic lupus erythematosus. Rheumatology and rehabilitation, 1982, Volume: 21, Issue:3 Topics: Adult; Allopurinol; Gout; Humans; Lupus Erythematosus, Systemic; Male; Probenecid	1982
[Effect of long-term base therapy on the clinical picture of gout]. Terapevticheskii arkhiv, 1981, Volume: 53, Issue:2 Topics: Adult; Allopurinol; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Gout; Humans; Male; Middle Aged; Probenecid; Sulfinpyrazone; Time Factors; Uric Acid	1981
Selected physiologic and drug effects on serum uric acid levels in an elderly population. Journal of the American Geriatrics Society, 1981, Volume: 29, Issue:6 Topics: Aged; Allopurinol; Diuretics; Female; Humans; Hypertension; Male; Obesity; Probenecid; Thyroid Diseases; Uric Acid	1981
Diagnostic and therapeutic aids in gout and hyperuricemia. Medical times, 1981, Volume: 109, Issue:8 Topics: Acute Disease; Allopurinol; Arthritis, Rheumatoid; Colchicine; Diagnosis, Differential; Gout; Humans; Probenecid; Uremia; Uric Acid; Uricosuric Agents	1981
Effects of exercise performance on drugs used in musculoskeletal disorders. Medicine and science in sports and exercise, 1981, Volume: 13, Issue:4 Topics: Allopurinol; Analgesics; Anti-Inflammatory Agents; Bone Diseases; Colchicine; Gout; Humans; Muscle Relaxants, Central; Muscular Diseases; Physical Exertion; Probenecid; Prostaglandins; Uric Acid	1981
Nasal secretion of the ozone scavenger uric acid. The American review of respiratory disease, 1993, Volume: 148, Issue:2 Topics: Albumins; Antioxidants; Humans; Lactoferrin; Methacholine Chloride; Muramidase; Nasal Mucosa; Nasal Provocation Tests; Ozone; Plasma; Probenecid; Turbinates; Uric Acid; Xanthine Oxidase	1993
Gout due to xanthine derivatives. British journal of rheumatology, 1997, Volume: 36, Issue:10 Topics: Allopurinol; Aminophylline; Asthma; Benzbromarone; Bronchodilator Agents; Drug Therapy, Combination; Female; Gout; Humans; Middle Aged; Probenecid; Theophylline; Uric Acid; Uricosuric Agents	1997
[Gout: physiopathology, diagnosis, course, treatment]. La Revue du praticien, 1998, Sep-01, Volume: 48, Issue:13 Topics: Adult; Aged; Allopurinol; Arthritis, Gouty; Benzbromarone; Diagnosis, Differential; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Synovial Fluid; Uric Acid; Uricosuric Agents	1998
[Hyperuricemia and gout--treatment]. Deutsche medizinische Wochenschrift (1946), 2002, Feb-01, Volume: 127, Issue:5 Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug Therapy, Combination; Glucocorticoids; Gout; Gout Suppressants; Humans; Kidney Calculi; Kidney Diseases; Probenecid; Time Factors; Uric Acid; Uricosuric Agents	2002
4-HYDROXYPYRAZOLO (3,4-D) PYRIMIDINE (HPP) IN THE TREATMENT OF GOUT: PRELIMINARY OBSERVATIONS. Annals of the rheumatic diseases, 1964, Volume: 23 Topics: Blood; Colchicine; Diet; Diet Therapy; Drug Therapy; Enzyme Inhibitors; Geriatrics; Gout; Humans; Probenecid; Purines; Pyrazoles; Pyrimidines; Toxicology; Uric Acid; Urine; Xanthine Oxidase; Xanthines	1964
THE RENAL EXCRETION OF OXYPURINES. The Journal of clinical investigation, 1965, Volume: 44 Topics: Enzyme Inhibitors; Fluids and Secretions; Gout; Hypoxanthines; Kidney; Pharmacology; Physiology; Probenecid; Purines; Pyrimidines; Renal Elimination; Salicylates; Spectrophotometry; Sulfinpyrazone; Uricosuric Agents; Urine; Xanthine Oxidase; Xanthines	1965
Febuxostat--treatment for hyperuricemia and gout? The New England journal of medicine, 2005, Dec-08, Volume: 353, Issue:23 Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thiazoles; Uric Acid; Xanthine Oxidase	2005
Uric acid lowering therapy: prescribing patterns in a large cohort of older adults. Annals of the rheumatic diseases, 2008, Volume: 67, Issue:5 Topics: Age Factors; Aged; Aged, 80 and over; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Black or African American; Cohort Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Gout; Gout Suppressants; Humans; Logistic Models; Male; Massachusetts; Patient Compliance; Probenecid; Sulfinpyrazone; White People	2008
Gout: joint pain and more. Harvard men's health watch, 2007, Volume: 12, Issue:5 Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Gout; Gout Suppressants; Humans; Male; Probenecid; Uric Acid; Uricosuric Agents	2007
Opportunities for improving medication use and monitoring in gout. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:8 Topics: Aged; Allopurinol; Biomarkers; Colchicine; Drug Administration Schedule; Drug Monitoring; Female; Gout; Gout Suppressants; Guideline Adherence; Humans; Male; Middle Aged; Practice Guidelines as Topic; Probenecid; Quality of Health Care; Renal Insufficiency; Treatment Outcome; Uric Acid	2009
Adherence with urate-lowering therapies for the treatment of gout. Arthritis research & therapy, 2009, Volume: 11, Issue:2 Topics: Age Factors; Allopurinol; Female; Gout; Gout Suppressants; Humans; Male; Medication Adherence; Middle Aged; Probenecid; Sulfinpyrazone; Uric Acid	2009
Ultrasonography shows disappearance of monosodium urate crystal deposition on hyaline cartilage after sustained normouricemia is achieved. Rheumatology international, 2010, Volume: 30, Issue:4 Topics: Aged; Aged, 80 and over; Allopurinol; Cartilage, Articular; Colchicine; Crystallization; Female; Gout; Gout Suppressants; Humans; Hyaline Cartilage; Joints; Male; Middle Aged; Probenecid; Treatment Outcome; Ultrasonography; Uric Acid	2010
On call. I've had gout for many years. I used to take Zyloprim without any problems, but I just had a severe allergic reaction, so my doctor switched me to Benemid. I'm doing okay, but the drug sometimes upsets my stomach. Do you have any suggestions? Harvard men's health watch, 2010, Volume: 14, Issue:6 Topics: Allopurinol; Drug Hypersensitivity; Gastritis; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Uric Acid; Uricosuric Agents	2010
Prevalence of contraindications and prescription of pharmacologic therapies for gout. The American journal of medicine, 2011, Volume: 124, Issue:2 Topics: Aged; Aged, 80 and over; Allopurinol; Colchicine; Comorbidity; Contraindications; Diabetes Mellitus; Drug Prescriptions; Female; Gastroesophageal Reflux; Glucocorticoids; Gout; Gout Suppressants; Hepatitis, Chronic; Humans; Hypertension; Male; Middle Aged; Prevalence; Probenecid; Renal Insufficiency, Chronic; Severity of Illness Index; Uricosuric Agents	2011
Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid. PLoS neglected tropical diseases, 2011, Volume: 5, Issue:9 Topics: Acute Kidney Injury; Allopurinol; Animals; Antimetabolites; Crotalus; Male; Mice; Probenecid; Snake Bites; Snake Venoms; Survival Analysis; Uricosuric Agents	2011
How clinical and research failures lead to suboptimal prescribing: the example of chronic gout. BMJ (Clinical research ed.), 2011, Dec-01, Volume: 343 Topics: Allopurinol; Chronic Disease; Drug Discovery; Drug Utilization; Gout; Gout Suppressants; Guideline Adherence; Humans; Practice Guidelines as Topic; Practice Patterns, Physicians'; Probenecid	2011
Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid. The Medical journal of Malaysia, 2012, Volume: 67, Issue:1 Topics: Allopurinol; Chronic Disease; Contraindications; Febuxostat; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Thiazoles	2012
Adherence to uric acid treatment guidelines in a rheumatology clinic. Clinical rheumatology, 2012, Volume: 31, Issue:12 Topics: Aged; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Guideline Adherence; Humans; Male; Middle Aged; Probenecid; Retrospective Studies; Thiazoles; Treatment Outcome; Uric Acid	2012
Changes of plasma concentration of osteoprotegerin and its association with endothelial dysfunction before and after hypouricemic therapy in patients with hyperuricemia. Modern rheumatology, 2015, Volume: 25, Issue:1 Topics: Adult; Aged; Allopurinol; Endothelium, Vascular; Female; Humans; Hyperuricemia; Male; Middle Aged; Osteoprotegerin; Probenecid; Treatment Outcome; Uricosuric Agents	2015
Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice. Journal of hepatology, 2015, Volume: 63, Issue:5 Topics: Adenosine Triphosphate; Adjuvants, Pharmaceutic; Allopurinol; Animals; Antimetabolites; Cells, Cultured; Disease Models, Animal; Fatty Liver, Alcoholic; Female; Hepatocytes; Inflammasomes; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Probenecid; Signal Transduction; Uric Acid	2015
The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012. Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4 Topics: Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Colchicine; Comorbidity; Diabetes Mellitus; Febuxostat; Female; Glucocorticoids; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Incidence; Male; Middle Aged; Population Growth; Prevalence; Probenecid; Sulfinpyrazone; Uricosuric Agents	2017
Achieving serum urate targets in gout: an audit in a gout-oriented rheumatology practice. International journal of rheumatic diseases, 2017, Volume: 20, Issue:7 Topics: Aged; Allopurinol; Biomarkers; Drug Substitution; Febuxostat; Female; Gout; Gout Suppressants; Humans; Male; Medical Audit; Medication Adherence; Practice Guidelines as Topic; Probenecid; Retrospective Studies; Rheumatology; Time Factors; Treatment Outcome; Uric Acid	2017
Cost-effectiveness analysis of HLA-B58: 01 genetic testing before initiation of allopurinol therapy to prevent allopurinol-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in a Malaysian population. Pharmacogenetics and genomics, 2018, Volume: 28, Issue:2* Topics: Alleles; Allopurinol; Cost-Benefit Analysis; Female; Genetic Testing; Genotype; Heterozygote; HLA-B Antigens; Humans; Malaysia; Male; Middle Aged; Probenecid; Quality-Adjusted Life Years; Risk Factors; Stevens-Johnson Syndrome	2018
Treating Gout in Patients With Cardiovascular Disease: Mutual Benefit or Unintended Consequences? Journal of the American College of Cardiology, 2018, 03-06, Volume: 71, Issue:9 Topics: Aged; Allopurinol; Cardiovascular Diseases; Gout; Humans; Probenecid; Risk Factors	2018
Cardiovascular Risks of Probenecid Versus Allopurinol in Older Patients With Gout. Journal of the American College of Cardiology, 2018, 03-06, Volume: 71, Issue:9 Topics: Age Factors; Aged; Aged, 80 and over; Allopurinol; Cardiovascular Diseases; Cohort Studies; Female; Gout; Gout Suppressants; Humans; Male; Medicare; Probenecid; Risk Factors; United States; Uricosuric Agents	2018
Urate-Lowering Therapy in Moderate to Severe Chronic Kidney Disease. The Permanente journal, 2018, Volume: 22 Topics: Aged; Allopurinol; Cohort Studies; Febuxostat; Female; Glomerular Filtration Rate; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Probenecid; Renal Insufficiency, Chronic; Retrospective Studies; Risk Factors; Severity of Illness Index; Uric Acid; Uricosuric Agents	2018
Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007-2016. Arthritis & rheumatology (Hoboken, N.J.), 2019, Volume: 71, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Nutrition Surveys; Prevalence; Probenecid; United States; Uric Acid; Uricosuric Agents; Young Adult	2019
[Simultaneous determination of allopurinol, probenecid, benzbromarone in dietary supplements by ultra high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography, 2019, Feb-08, Volume: 37, Issue:2 Topics: Allopurinol; Benzbromarone; Chromatography, High Pressure Liquid; Dietary Supplements; Probenecid; Tandem Mass Spectrometry	2019
Burden and management of gout in a multi-ethnic Asian cohort. Rheumatology international, 2020, Volume: 40, Issue:7 Topics: Adult; Aged; Allopurinol; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus; Dyslipidemias; Emergency Service, Hospital; Ethnicity; Febuxostat; Female; Gout; Gout Suppressants; Hospitalization; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Probenecid; Renal Insufficiency, Chronic; Severity of Illness Index; Singapore; Treatment Outcome; Uric Acid	2020
High-Protein Diet Induces Hyperuricemia in a New Animal Model for Studying Human Gout. International journal of molecular sciences, 2020, Mar-20, Volume: 21, Issue:6 Topics: Allopurinol; Animal Structures; Animals; Chickens; Crystallization; Diet, High-Protein; Disease Models, Animal; Gout; Hyperuricemia; Kidney; Liver; Probenecid; Synovial Fluid; Uric Acid	2020
Trends in Utilization of Urate-Lowering Therapies Following the US Food and Drug Administration's Boxed Warning on Febuxostat. Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:3 Topics: Allopurinol; Cardiovascular Diseases; Cause of Death; Drug Labeling; Febuxostat; Gout; Gout Suppressants; Humans; Mortality; Polyethylene Glycols; Practice Patterns, Physicians'; Probenecid; Risk Factors; Thioglycolates; Triazoles; United States; United States Food and Drug Administration; Urate Oxidase	2021