Page last updated: 2024-08-16

probenecid and acetazolamide

probenecid has been researched along with acetazolamide in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199019 (51.35)18.7374
1990's3 (8.11)18.2507
2000's4 (10.81)29.6817
2010's10 (27.03)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Akdemir, A; Carradori, S; Ceruso, M; D'Ascenzio, M; Secci, D; Supuran, CT; Vullo, D1
Akdemir, A; Carradori, S; Ceruso, M; Chimenti, P; D'Ascenzio, M; De Monte, C; Mollica, A; Sabia, R; Supuran, CT1
Akdemir, A; Carradori, S; Ceruso, M; Costante, R; Macedonio, G; Mollica, A; Stefanucci, A; Supuran, CT1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bohn, DL; Fanelli, GM; Zacchei, AG1
Bowers, MB; Cohen, DJ; Shaywitz, BA1
Arslan, Y; Diezi, J; Peters, G; Roch-Ramel, F1
Baer, JE; Beyer, KH1
Bonet Domingo, E; García Alvarez-Coque, MC; Medina Hernández, MJ; Ramis Ramos, G1
Dyas, ML; Johanson, CE; Parandoosh, Z1
Barry, JA; Harig, JM; Ramaswamy, K; Soergel, KH1
Harnish, PP; Mukherji, M1
Harnish, PP; Samuel, K1
Boyd, CA; Gerard, EM; Hollander, D1
Hugentobler, G; Meier, PJ; Rahm, I; Valantinas, J1
Pederson, JE; Tsuboi, S1
Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K1
Planas-Bohne, F1
Levy, L; Smith, JK1
Ferry, AP; Lichtig, M1
Bleyer, WA; Bode, U; Glaubiger, DL; Magrath, IT; Poplack, DG1
Hikichi, T; Mori, F; Takahashi, J; Yoshida, A1
BAER, RB; BENEDEK, T; ROSENTHAL, IM; ZIMMERMAN, HJ1
HAZARD, R; PIGNARD, P1
HAKKINEN, I; HARTIALA, K; KASANEN, A; VANHA-PERTTULA, T1
HAEKKINEN, I; HARTIALA, K; KASANEN, A; RAUSSI, M1
KUNIN, CM1

Reviews

1 review(s) available for probenecid and acetazolamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

36 other study(ies) available for probenecid and acetazolamide

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies.
    Bioorganic & medicinal chemistry, 2014, Aug-01, Volume: 22, Issue:15

    Topics: Amides; Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Humans; Molecular Docking Simulation; Probenecid; Protein Binding; Structure-Activity Relationship; Sulfonamides

2014
New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Crystallography, X-Ray; Enzyme Assays; Humans; Molecular Docking Simulation; Probenecid; Protein Binding; Sensitivity and Specificity; Structure-Activity Relationship

2015
Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Humans; Molecular Docking Simulation; Probenecid; Structure-Activity Relationship

2015
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Renal excretion of a slauretic-uricosuric agent (MK-196) and interaction with a urate-retaining drug, pyrazinoate, in the chimpanzee.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:2

    Topics: Acetazolamide; Animals; Diuresis; Drug Interactions; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Indans; Indenes; Kidney; Male; p-Aminohippuric Acid; Pan troglodytes; Probenecid; Pyrazinamide; Pyrazines; Sodium Chloride; Time Factors; Uric Acid; Uricosuric Agents

1977
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
    Neurology, 1975, Volume: 25, Issue:1

    Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Phenobarbital; Phenylacetates; Phenytoin; Primidone; Probenecid

1975
[Pharmacologic modifications of renal tubular transport].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1976, Volume: 32, Issue:4-6

    Topics: Acetazolamide; Biological Transport; Cell Membrane Permeability; Diuretics; Furosemide; Humans; Kidney Tubules; Probenecid; Uric Acid

1976
The site and mode of action of some sulfonamide-derived diuretics.
    The Medical clinics of North America, 1975, Volume: 59, Issue:3

    Topics: Acetazolamide; Aminohippuric Acids; Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Chlorides; Chlorothiazide; Chlorthalidone; Cyclopenthiazide; Depression, Chemical; Dichlorphenamide; Diffusion; Diuretics; Hydrochlorothiazide; Kidney Cortex; Kidney Medulla; Natriuresis; Probenecid; Rabbits; Sodium; Trichlormethiazide

1975
High-performance liquid chromatographic determination of diuretics in urine by micellar liquid chromatography.
    Journal of chromatography, 1992, Nov-06, Volume: 582, Issue:1-2

    Topics: Acetazolamide; Bendroflumethiazide; Chlorothiazide; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Micelles; Probenecid; Sodium Dodecyl Sulfate

1992
Maturational differences in acetazolamide-altered pH and HCO3 of choroid plexus, cerebrospinal fluid, and brain.
    The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 2

    Topics: Acetazolamide; Acid-Base Equilibrium; Aging; Animals; Bicarbonates; Blood; Brain; Choroid Plexus; Dimethadione; Hydrogen-Ion Concentration; Mannitol; Probenecid; Rats; Rats, Inbred Strains; Tissue Distribution

1992
Transport of propionate by human ileal brush-border membrane vesicles.
    The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Adult; Biological Transport; Carboxylic Acids; Chlorides; Female; Furosemide; Harmaline; Humans; Ileum; Intestinal Mucosa; Ions; Kinetics; Male; Microvilli; Probenecid; Propionates; Valinomycin

1991
Penetration of vascular contrast media into brain tissue and cerebrospinal fluid. An experimental study in rats.
    Investigative radiology, 1989, Volume: 24, Issue:6

    Topics: Acetazolamide; Animals; Brain; Brain Chemistry; Cerebrospinal Fluid; Diatrizoate; Infusions, Intravenous; Iohexol; Male; Premedication; Probenecid; Rats; Rats, Inbred Strains

1989
Pharmacologic manipulation of the flushing action of cerebrospinal fluid. Effect on CSF diatrizoate levels.
    Investigative radiology, 1988, Volume: 23, Issue:12

    Topics: Acetazolamide; Aminophylline; Animals; Bucladesine; Carbachol; Cerebrospinal Fluid; Dexamethasone; Diatrizoate; Digoxin; Furosemide; Male; Premedication; Probenecid; Rats; Rats, Inbred Strains; Ritodrine; Salicylates; Salicylic Acid

1988
Transport of butyric acid in vascularly perfused anuran small intestine: importance of pH and anion transport.
    The American journal of physiology, 1986, Volume: 250, Issue:4 Pt 1

    Topics: 3-O-Methylglucose; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Animals; Anions; Biological Transport; Butyrates; Butyric Acid; Hydrogen-Ion Concentration; Intestine, Small; Kinetics; Methylglucosides; Perfusion; Probenecid; Rana esculenta

1986
Bicarbonate sulfate exchange in canalicular rat liver plasma membrane vesicles.
    The American journal of physiology, 1987, Volume: 253, Issue:4 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Animals; Bicarbonates; Biological Transport, Active; Cell Membrane; Furosemide; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Membrane Potentials; Probenecid; Rats; Rats, Inbred Strains; Substrate Specificity; Sulfates; Taurine

1987
Acetazolamide effect on the inward permeability of the blood-retinal barrier to carboxyfluorescein.
    Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:1

    Topics: Acetazolamide; Animals; Blood-Retinal Barrier; Capillary Permeability; Female; Fluoresceins; Macaca fascicularis; Male; Probenecid

1987
Distribution of chlorpromazine in a simplified blood influenced by various drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 278, Issue:1

    Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental

1973
[Studies on the modification of the renal excretion of D-penicillamine in the rat (author's transl)].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1974, Volume: 163, Issue:1

    Topics: Acetazolamide; Ammonium Chloride; Animals; Carbon Radioisotopes; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Kidney; Liver; Male; Penicillamine; Probenecid; Rats; Skin

1974
Retention of a sulfated polysaccharide (SPG) and attempts at modifying this retention.
    Agents and actions, 1972, Volume: 2, Issue:5

    Topics: Acetazolamide; Animals; Cortisone; Dogs; Haplorhini; Histocytochemistry; Liver; Lung; Polysaccharides; Probenecid; Protamines; Rats; Rats, Inbred Strains; Spleen; Sulfur; Sulfur Isotopes; Thorium; Time Factors; Zymosan

1972
Gouty arthritis as a complication of acetazolamide (Diamox) therapy for glaucoma.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1969, Volume: 4, Issue:2

    Topics: Acetazolamide; Colchicine; Glaucoma; Gout; Humans; Male; Middle Aged; Probenecid

1969
Active transport of methotrexate from cerebrospinal fluid in humans.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Acetazolamide; Adolescent; Biological Transport, Active; Cerebral Ventricles; Child; Half-Life; Humans; Infusions, Parenteral; Injections, Intraventricular; Kinetics; Methotrexate; Probenecid

1980
Effect of acetazolamide on outward permeability of blood-retina barrier using differential vitreous flyorophotometry.
    Current eye research, 2001, Volume: 23, Issue:3

    Topics: Acetazolamide; Animals; Biological Transport, Active; Blood-Retinal Barrier; Capillary Permeability; Carbonic Anhydrase Inhibitors; Fluorescein; Fluoresceins; Fluorophotometry; Probenecid; Rabbits; Time Factors; Vitreous Body

2001
Renal excretion of phosphorus in pseudohypoparathyroidism; observations on the effects of probenecid and acetazoleamide in two patients.
    A.M.A. archives of internal medicine, 1957, Volume: 99, Issue:1

    Topics: Acetazolamide; Disease; Humans; Parathyroid Diseases; Parathyroid Glands; Phosphorus; Phosphorus, Dietary; Probenecid; Pseudohypoparathyroidism; Renal Elimination

1957
[Sulfonamide inhibitors of tubular function, carbonic anhydrase inhibitors & hypoglycemics].
    Actualites pharmacologiques, 1957, Volume: 10

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Humans; Hypoglycemic Agents; Probenecid; Sulfanilamide; Sulfanilamides; Sulfonamides

1957
Effect of some tubular inhibiting agents on the urinary output of sulphates.
    Annales medicinae experimentalis et biologiae Fenniae, 1961, Volume: 39

    Topics: Acetazolamide; Blood Pressure; Diuretics; Humans; Organomercury Compounds; p-Aminohippuric Acid; Probenecid; Sulfates

1961
EFFECT OF SOME TUBULAR INHABITING AGENTS ON THE URINARY OUTPUT OF TOTAL GLUCURONIDES.
    Annales medicinae experimentalis et biologiae Fenniae, 1963, Volume: 41

    Topics: Acetazolamide; Diuretics; Glucuronates; Glucuronides; Kidney Function Tests; Kidney Tubules; Organomercury Compounds; p-Aminohippuric Acid; Pharmacology; Phenolphthaleins; Probenecid; Rabbits; Research; Urine

1963
INHIBITORS OF PENICILLIN BINDING TO SERUM PROTEINS.
    The Journal of laboratory and clinical medicine, 1965, Volume: 65

    Topics: Acetazolamide; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimetabolites; Aspirin; Benzoates; Biguanides; Blood Proteins; Carbon Isotopes; Chlorothiazide; Diuretics; Ethacrynic Acid; Guanidines; Oxazoles; p-Aminohippuric Acid; Penicillin G; Penicillin V; Penicillins; Pharmacology; Phenylbutazone; Probenecid; Rabbits; Research; Salicylates; Sulfinpyrazone; Sulfonamides; Tolbutamide

1965