proadifen has been researched along with warfarin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (81.82) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Moilanen, ML; Pelkonen, O | 1 |
| Anderson, J; Nievel, JG; Skrbic, TR | 1 |
| Herczeg, T; Mathur, PP; Reavey-Cantwell, NH; Smyth, RD | 1 |
| Balls, M; Clothier, RH; Fry, JR; Horner, SA | 1 |
| Ellen, JM; Farber, JL; Gerson, RJ; Gilfor, D; Serroni, A | 1 |
| Finnen, MJ; Shuster, S | 1 |
| O'Brien, PJ; Rahimtula, AD | 1 |
| Creaven, PJ; Parke, DV; Williams, RT | 1 |
| Feuer, G | 1 |
| Bell, RG; Caldwell, PT; Ren, P | 1 |
| Frommer, U; Ullrich, V; Weber, P | 1 |
| Letist, D; Reuse, J; Thonnart, N | 1 |
| DiAugustine, RP; Eling, TE | 1 |
| Devereux, TR; Fouts, JR | 1 |
| Bachmann, KA; Sullivan, TJ | 1 |
| Hines, RN; Nelson, RE; Prough, RA; Sieg, MS; Wiebkin, P | 1 |
| Bridges, JW; Chasseaud, LF; Poole, A | 1 |
| Grafstöm, R; Stohs, SJ | 1 |
| Commandeur, JN; Goeptar, AR; Groot, EJ; Scheerens, H; Vermeulen, NP | 1 |
| Fujita, S; Ishizuka, M; Min, H; Okajima, F; Sakamoto, KQ; Tanaka, KD; Tanikawa, T | 1 |
| Fu, Y; Liang, XF; Liu, QL; Ruan, H; Su, MQ; Wang, XM; Zhang, Z; Zhu, X | 1 |
22 other study(ies) available for proadifen and warfarin
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The specificity and multiplicity of human placental xenobiotic-metabolizing monooxygenase system studied by potential substrates, inhibitors and gel electrophoresis.
Topics: Aldrin; Aminopyrine; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Biotransformation; Biphenyl Compounds; Coumarins; Electrophoresis, Polyacrylamide Gel; Female; Flavonoids; Humans; Microsomes; Placenta; Pregnancy; Proadifen; Smoking | 1979 |
Studies on the relationship between induction of drug-metabolizing enzymes, liver enlargement and ascorbic acid excretion in rodents.
Topics: Animals; Ascorbic Acid; Azauridine; Butylated Hydroxytoluene; Coumarins; Dactinomycin; Enzyme Induction; Female; Glucuronates; Hepatomegaly; Liver; Orotic Acid; Phenobarbital; Proadifen; Rats; Transcription, Genetic; Uracil; Uracil Nucleotides | 1976 |
Induction of hepatic enzymes by methaqualone and effect on warfarin-induced hypoprothrombinemia.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Enzyme Induction; Hexobarbital; Hypoprothrombinemias; Liver; Male; Methaqualone; Phenobarbital; Proadifen; Prothrombin Time; Rats; Sleep; Time Factors; Warfarin | 1976 |
The detection of cytotoxicity produced by short-lived reactive intermediates: a study with bromobenzene.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Bromobenzenes; Carcinogens; Cell Survival; Cells, Cultured; Coumarins; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Oxidoreductases, O-Demethylating; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Subcellular Fractions | 1987 |
Killing of cultured hepatocytes by the mixed-function oxidation of ethoxycoumarin.
Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Coumarins; Deferoxamine; Glutathione; Glutathione Reductase; Iron; Lipid Peroxides; Liver; Oxidation-Reduction; Phenylenediamines; Proadifen; Rats; Rats, Inbred Strains | 1986 |
Phase 1 and Phase 2 drug metabolism in isolated epidermal cells from adult hairless mice and in whole human hair follicles.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Epidermis; Female; Hair; Humans; Kinetics; Male; Mice; Mice, Hairless; Proadifen; Spectrometry, Fluorescence; Umbelliferones | 1985 |
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450.
Topics: Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Coumarins; Cyanides; Cytochrome P-450 Enzyme System; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Phenobarbital; Phenols; Phenylenediamines; Proadifen; Rabbits; Rats; Sodium Dodecyl Sulfate; Species Specificity; Superoxide Dismutase; Time Factors | 1974 |
A spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes.
Topics: Animals; Anura; Birds; Carnivora; Cats; Chloromercuribenzoates; Coumarins; Fluorescence; Fluorometry; Guinea Pigs; In Vitro Techniques; Insecta; Liver; Mice; Microsomes; Mixed Function Oxygenases; NAD; NADP; Physiology, Comparative; Poultry; Proadifen; Rabbits; Rats; Subcellular Fractions | 1965 |
3-Hydroxylation of coumarin or 4-methylcoumarin by rat-liver microsomes and its induction by 4-methylcoumarin given orally.
Topics: Animals; Coumarins; Dactinomycin; Enzyme Induction; Female; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; NAD; NADP; Phospholipases; Proadifen; Proteins; Rats; Surface-Active Agents | 1970 |
Warfarin and metabolism of vitamin K1.
Topics: Animals; Carbon Radioisotopes; Epoxy Compounds; Half-Life; Liver; Male; Proadifen; Prothrombin; Rats; Tritium; Vitamin K; Vitamin K Deficiency; Warfarin | 1974 |
Characterisation of cytochrome P-450 species in rat liver microsomes, I. Differences in the O-dealkylation of 7-ethoxycoumarin after pretreatment with phenobarbital and 3-methylcholanthrene.
Topics: Animals; Coumarins; Cyclohexanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Ethyl Ethers; Female; Flavins; Hydrogen-Ion Concentration; Kinetics; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
[Influence of SKF 525A on the kinetics and action of an antivitamin K in the rat].
Topics: Administration, Oral; Animals; Anticoagulants; Benzene Derivatives; Biotransformation; Blood Coagulation; Blood Coagulation Tests; Coumarins; Drug Synergism; Female; Injections, Intraperitoneal; Kinetics; Proadifen; Rats; Thrombin; Time Factors; Vitamin K | 1974 |
A role for phospholipids in the binding and metabolism of drugs by hepatic microsomes. Use of the fluorescent hydrophobic probe 1-anilinonaphthalene-8-sulphonate.
Topics: Aniline Compounds; Animals; Benzphetamine; Ethylamines; Fluorescence; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Naphthalenes; Pharmaceutical Preparations; Phosphatidylcholines; Phospholipases; Phospholipids; Proadifen; Rats; Receptors, Drug; Spectrophotometry; Sulfonic Acids; Trypsin; Warfarin | 1971 |
Xenobiotic metabolism by alveolar type II cells isolated from rabbit lung.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Coumarins; Cytochrome P-450 CYP2A6; Cytochromes; In Vitro Techniques; Male; Mixed Function Oxygenases; NAD; NADP; Proadifen; Pulmonary Alveoli; Rabbits | 1981 |
Dispositional and pharmacodynamic characteristics of brodifacoum in warfarin-sensitive rats.
Topics: 4-Hydroxycoumarins; Animals; Dose-Response Relationship, Drug; Half-Life; Intestine, Small; Liver; Male; Phenobarbital; Proadifen; Prothrombin; Rats; Rats, Inbred Strains; Tissue Distribution; Warfarin | 1983 |
Inhibition of metabolism-mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma (line P815) cells.
Topics: Animals; Biotransformation; Cell Survival; Cells, Cultured; Coumarins; Cyclophosphamide; Hydrazines; Liver; Male; Mast-Cell Sarcoma; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Sarcoma, Experimental | 1982 |
Preparation and properties of primary maintenance cultures of adult rabbit hepatocytes.
Topics: Ampyrone; Animals; Blood Proteins; Cells, Cultured; Coumarins; Fibroblasts; Liver; Male; Mixed Function Oxygenases; Proadifen; Rabbits | 1982 |
Inhibitors of 7-ethoxyresorufin and 7-ethoxycoumarin de-ethylases in rat small intestinal microsomes and cells.
Topics: Animals; Benzoflavones; Benzopyrenes; Coumarins; Cytochrome P-450 CYP1A1; Female; Intestine, Small; Methylcholanthrene; Metyrapone; Microsomes; Oxidoreductases; Proadifen; Rats; Rats, Inbred Strains; Rotenone | 1981 |
Cytotoxicity of mitomycin C and adriamycin in freshly isolated rat hepatocytes: the role of cytochrome P450.
Topics: Animals; Coumarins; Cytochrome P-450 Enzyme System; Doxorubicin; Drug Interactions; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Maleates; Metyrapone; Mitomycin; Proadifen; Rats; Rats, Wistar; Time Factors | 1994 |
Elevated warfarin metabolism in warfarin-resistant roof rats (Rattus rattus) in Tokyo.
Topics: Animals; Anticoagulants; Cytochrome P-450 Enzyme System; Drug Resistance; Enzyme Inhibitors; Female; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Proadifen; Rats; Rodenticides; Testosterone; Tokyo; Vitamin K Epoxide Reductases; Warfarin | 2007 |
Metabolism of dl-praeruptorin A in rat liver microsomes using HPLC-electrospray ionization tandem mass spectrometry.
Topics: Animals; Cardiovascular Agents; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drugs, Chinese Herbal; Enzyme Induction; Enzyme Inhibitors; Hydroxylation; Isoenzymes; Male; Membrane Proteins; Microsomes, Liver; Molecular Structure; Proadifen; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2011 |