Page last updated: 2024-08-16

proadifen and morphine

proadifen has been researched along with morphine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199033 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Ho, TK; LaBella, FS; Pinsky, C1
Bridges, JW; Elcombe, CR; Illing, HP; King, LJ; Netter, KJ; Nimmo-Smith, RH; Wolf, CR1
Saitoh, M; Sasaki, K; Takayanagi, G1
Lee, RL; Spencer, PS1
Leander, JD1
Holaday, JW; Law, PY; Li, CH; Loh, HH1
Chen, CF; Chow, SY; Tsou, CT1
De Nie, LC; Kalant, H; Khanna, JM; Siemens, AJ1
Stevenson, IH; Turnbull, MJ1
Gigon, PL; Gillette, JR; Gram, TE1
Kato, R; Onoda, K; Takayanagi, M1
Burns, B; Gurtner, GH1
Sladek, NE1
Takemori, AE; Wang, JH1
Fujimoto, JM; Hakim, R1
Fujimoto, M; Kitahara, A; Miyao, K; Ogo, T1
Alvares, AP; Mannering, GJ1
Contreras, E; Quijada, L; Tamayo, L1
Castro, JA; Gillette, JR; Sasame, HA; Sussman, H1
Mannering, GJ; Stitzel, RE; Tephly, TR1
Huidobro, F; Huidobro, JP; LarraĆ­n, G1
Anders, MW2
Mannering, GJ; Sladek, NE1
Anders, MW; Mannering, GJ2
Dykstra, LA1
Burkhalter, A; Masten, LW; Peterson, GR; Way, EL1
Fujimoto, JM; Imamura, T1
MANNERING, GJ; RUBIN, A; TEPHYL, TR1
ADLER, TK; VEATCH, RM; WAY, EL1
HENDERSON, JF; MAZEL, P1

Other Studies

33 other study(ies) available for proadifen and morphine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Opiate properties of SKF 525A.
    Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:4

    Topics: Analgesia; Animals; Injections, Intraventricular; Male; Methadone; Morphine; Naloxone; Narcotics; Proadifen; Rats; Reaction Time; Receptors, Opioid

1978
Measurement of substrate-induced oxygen uptake during microsomal drug oxidation using a gold micro-electrode.
    Xenobiotica; the fate of foreign compounds in biological systems, 1975, Volume: 5, Issue:3

    Topics: Animals; Biphenyl Compounds; Cell-Free System; Gold; Hexobarbital; Kinetics; Male; Microelectrodes; Microsomes, Liver; Morphine; Morphine Derivatives; NADP; Naphthalenes; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Polarography; Proadifen; Rats

1975
[Drug interaction on antitumor drugs I. Antitumor activity of cyclophosphamide in mice consecutively administered aminopyrine, chlorpromazine, or morphine (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:6

    Topics: Aminopyrine; Animals; Antineoplastic Agents; Chlorpromazine; Cycloheximide; Cyclophosphamide; Drug Interactions; Male; Mice; Morphine; Pentobarbital; Proadifen; Sleep

1979
The effect of clomipramine and other amine-uptake inhibitors on morphine analgesia in laboratory animals.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 4

    Topics: Analgesia; Animals; Chlorpromazine; Clomipramine; Dibenzazepines; Dibenzocycloheptenes; Drug Synergism; Drug Tolerance; Male; Maprotiline; Mice; Morphine; Pentazocine; Phenyl Ethers; Proadifen; Propylamines; Quipazine; Rats

1977
An analysis of normeperidine's contribution to the rate-decreasing effects of meperidine.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:2

    Topics: Animals; Columbidae; Conditioning, Operant; Dealkylation; Male; Meperidine; Morphine; Naloxone; Pentobarbital; Proadifen; Reinforcement Schedule; Time Factors

1978
Adrenal steroids indirectly modulate morphine and beta-endorphin effects.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Analgesics; Animals; Cycloheximide; Dexamethasone; Drug Interactions; Endorphins; Male; Morphine; Proadifen; Rats; Reaction Time

1979
Interactions between ketamine and other drugs.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1975, Volume: 74, Issue:4

    Topics: Animals; Autonomic Agents; Drug Interactions; Female; Hypnotics and Sedatives; Ketamine; Male; Morphine; Phenobarbital; Proadifen; Rats; Tranquilizing Agents

1975
Effects of various psychoative drugs on the metabolism of delta-tetrahydrocannabinol by rats in vitro and in vivo.
    European journal of pharmacology, 1975, Volume: 31, Issue:1

    Topics: Animals; Barbiturates; Bile; Cannabis; Carbon Radioisotopes; Dextroamphetamine; Dronabinol; In Vitro Techniques; Kinetics; Liver; Male; Meprobamate; Mescaline; Morphine; Proadifen; Psychotropic Drugs; Rats

1975
A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs.
    British journal of pharmacology, 1974, Volume: 50, Issue:4

    Topics: Aging; Amphetamine; Animals; Anti-Anxiety Agents; Barbiturates; Body Weight; Carbon Radioisotopes; Cerebral Ventricles; Chlorpromazine; Dose-Response Relationship, Drug; Ethanol; Female; Humans; Hypnotics and Sedatives; Injections; Liver; Male; Morphine; Pentobarbital; Proadifen; Rats; Sex Factors; Sleep; Substance Withdrawal Syndrome; Time Factors

1974
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
    Biochemical and biophysical research communications, 1968, May-23, Volume: 31, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases

1968
Species difference in the inhibition of drug metabolism by liver microsomes by different inhibitors.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Cocaine; Depression, Chemical; Drug Antagonism; Ethylamines; Hexobarbital; Histamine H1 Antagonists; Kinetics; Male; Meperidine; Mice; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Pentobarbital; Pharmaceutical Preparations; Phenacetin; Phenylhydrazines; Piperazines; Proadifen; Rabbits; Rats; Species Specificity; Zoxazolamine

1969
Possible facilitated transport of oxygen across the placenta.
    Nature, 1972, Dec-22, Volume: 240, Issue:5382

    Topics: Animals; Argon; Capillary Permeability; Cytochrome P-450 Enzyme Inhibitors; Deoxycholic Acid; Female; Maternal-Fetal Exchange; Meperidine; Morphine; Oxygen; Oxygen Consumption; Placenta; Pregnancy; Proadifen; Sheep; Sodium; Umbilical Veins; Uterus

1972
Therapeutic efficacy of cyclophosphamide as a function of inhibition of its metabolism.
    Cancer research, 1972, Volume: 32, Issue:9

    Topics: Alkylation; Animals; Azaguanine; Binding, Competitive; Carcinoma 256, Walker; Cyclophosphamide; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Gonadal Steroid Hormones; Male; Meperidine; Mercaptopurine; Metyrapone; Microsomes, Liver; Morphine; Phenacetin; Proadifen; Probenecid; Quinine; Rats

1972
Studies on the transport of morphine into the cerebrospinal fluid of rabbits.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:1

    Topics: Animals; Biological Transport; Blood Proteins; Cerebral Ventricles; Chromatography, Thin Layer; Codeine; Dinitrophenols; Drug Tolerance; Glucuronates; Hydrogen-Ion Concentration; Ligation; Male; Morphinans; Morphine; Nalorphine; Naloxone; Proadifen; Protein Binding; Rabbits; Renal Veins; Tritium; Water

1972
Inhibition of renal tubular transport of morphine by -diethylaminoethyl diphenylpropylacetate in the chicken.
    Biochemical pharmacology, 1971, Volume: 20, Issue:10

    Topics: Aminohippuric Acids; Animals; Biological Transport; Carbamates; Carbon Isotopes; Chickens; Countercurrent Distribution; Depression, Chemical; Female; Inulin; Kidney Tubules; Morphine; Pentobarbital; Piperidines; Proadifen; Regional Blood Flow; Tetraethylammonium Compounds

1971
[Analgesic effect of 2-methylaminoethyl 2,3-dihydrobenzofuran (EPS-4032); mode of action in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:6

    Topics: 5-Hydroxytryptophan; Aminopyrine; Analgesics; Animals; Benzofurans; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Drug Tolerance; Lethal Dose 50; Levallorphan; Male; Mice; Morphine; Nialamide; Pargyline; Phenobarbital; Proadifen; Reserpine; Tetrabenazine; Time Factors

1971
Two-substrate kinetics of drug-metabolizing enzyme systems of hepatic microsomes.
    Molecular pharmacology, 1970, Volume: 6, Issue:3

    Topics: Alkylation; Aniline Compounds; Animals; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Stereoisomerism

1970
Influence of nalorphine upon the synergistic effect of methyldopa and ergonovine on morphine analgesia.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 16, Issue:4

    Topics: Animals; Drug Synergism; Ergonovine; Female; Male; Methyldopa; Morphine; Nalorphine; Pain; Proadifen; Rats

1967
Diverse effects of SKF 525-A and antioxidants on carbon tetrachloride-induced changes in liver microsomal P-450 content and ethylmorphine metabolism.
    Life sciences, 1968, Feb-01, Volume: 7, Issue:3

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Cytochromes; Liver; Microsomes; Morphine; Pigments, Biological; Proadifen; Rats; Vitamin E

1968
Inhibition of drug metabolism. VI. Inhibition of hexobarbital metabolism in the isolated perfused liver of the rat.
    Molecular pharmacology, 1968, Volume: 4, Issue:1

    Topics: Animals; Chlorpromazine; Codeine; Hexobarbital; In Vitro Techniques; Liver; Male; Morphine; Narcotics; Proadifen; Rats

1968
Tolerance to morphine in the white mice.
    Acta physiologica latino americana, 1968, Volume: 18, Issue:1

    Topics: Aminopyrine; Animals; Behavior, Animal; Body Temperature; Body Weight; Drug Tolerance; Mice; Morphine; Phenobarbital; Proadifen; Sodium Salicylate

1968
Acetone enhancement of microsomal aniline para-hydroxylase activity.
    Archives of biochemistry and biophysics, 1968, Volume: 126, Issue:1

    Topics: Acetone; Anilides; Aniline Compounds; Animals; Computers; Dogs; Ethers, Cyclic; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Mixed Function Oxygenases; Morphine; Nitrobenzenes; Proadifen; Rabbits; Rats

1968
Inhibition of microsomal drug metabolism by methylenedioxybenzenes.
    Biochemical pharmacology, 1968, Volume: 17, Issue:11

    Topics: Aniline Compounds; Animals; Benzene Derivatives; Depression, Chemical; Dioxoles; Drug Synergism; Enzyme Induction; Glucosephosphate Dehydrogenase; Hexobarbital; Insecticides; Isocitrate Dehydrogenase; Liver; Male; Mice; Microsomes; Morphine; Proadifen; Rats; Sleep; Time Factors

1968
Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Animals; Benzene Derivatives; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Female; Formaldehyde; Kinetics; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Valerates

1969
Inhibition of drug metabolism. I. Kinetics of the inhibition of the N-demethylation of ethylmorphine by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and related compounds.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Animals; Cell Membrane Permeability; Enzymes; Glucosephosphate Dehydrogenase; In Vitro Techniques; Isocitrate Dehydrogenase; Kinetics; Liver; Male; Microsomes; Morphine; Proadifen; Rats

1966
Inhibition of drug metabolism. IV. Induction of drug metabolism by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and 2,4-dichloro-6-phenylphenoxyethylamine HBr (Lilly 18947) and the effect of induction on the inhibitory properties of SKF 525-A
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Animals; Antimetabolites; Enzymes; Hexobarbital; Male; Microsomes; Morphine; Phenobarbital; Proadifen; Proteins; Rats

1966
Meperidine's effect under shock titration and shock discrimination procedures.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:3

    Topics: Animals; Behavior, Animal; Electroshock; Haplorhini; Male; Meperidine; Morphine; Prejudice; Proadifen; Saimiri

1980
Tolerance to methadone lethality and microsomal enzyme induction in mice tolerant to and dependent on morphine.
    Drug and alcohol dependence, 1980, Volume: 5, Issue:1

    Topics: Animals; Body Weight; Drug Tolerance; Enzyme Induction; Humans; Inactivation, Metabolic; Lethal Dose 50; Liver; Male; Methadone; Mice; Microsomes, Liver; Morphine; Morphine Dependence; Oxidoreductases, N-Demethylating; Proadifen

1980
A new mode of action of SKD 525-A on morphine disposition studied by segmented retrograde intrabiliary injection (SRII) in the isolated in situ perfused rat liver.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1

    Topics: Animals; Bile; Glucuronates; Injections; Liver; Liver Function Tests; Male; Morphine; Perfusion; Proadifen; Rats

1980
INHIBITION OF HEXOBARBITAL METABOLISM BY ETHYLMORPHINE AND CODEINE IN THE INTACT RAT.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Acetanilides; Antimetabolites; Antitussive Agents; Blood; Codeine; Ethylmorphine; Hexobarbital; Meprobamate; Morphine; Pharmacology; Proadifen; Rats; Research

1964
THE IMPORTANCE OF STERIC CONFIGUA. ION IN CERTAIN MORPHINNE-MIMETIC ACTIONS OF SYNTHETIC ANALGETICS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 145

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Apnea; Chemical Phenomena; Chemistry; Methadone; Mice; Morphine; Nalorphine; Pain; Pharmacology; Proadifen; Research; Seizures; Toxicology

1964
STUDIES OF THE INDUCTION OF MICROSOMAL S-, N- AND O-DEMETHYLASES.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Alkylation; Amino Acids; Anilides; Barbiturates; Benzopyrenes; Codeine; Enzymes; Hydantoins; Liver; Meperidine; Microsomes; Morphine; Oxidoreductases, O-Demethylating; Pharmacology; Phenobarbital; Proadifen; Purines; Rats; Research

1964