Page last updated: 2024-08-16

proadifen and morphinans

proadifen has been researched along with morphinans in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Correia, MA; Mannering, GJ1
Illing, HP; Kunke, S; Netter, KJ1
Kamataki, T; Kitagawa, H1
Anders, MW; Gundu Rao, HR1
Bickel, MH; Gigon, PL1
Mannering, GJ; Parli, CJ1
Gigon, PL; Gillette, JR; Gram, TE1
Gillette, JR; Sasame, HA1
Conney, AH; Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; West, SB1
Allen, LM; Creaven, PJ1
Hildebrandt, AG1
Miranda, CL; Webb, RE1
McPhillips, JJ; Stevens, JT; Stitzel, RE1
Takemori, AE; Wang, JH1
Alvares, AP; Mannering, GJ1
Mannering, GJ; Sladek, NE1
Tsai, TH; Wu, JW1

Reviews

1 review(s) available for proadifen and morphinans

ArticleYear
The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions.
    Biochemical Society symposium, 1972, Volume: 34

    Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Ethylamines; Hydrogen-Ion Concentration; In Vitro Techniques; Isocitrate Dehydrogenase; Methylation; Metyrapone; Microsomes, Liver; Morphinans; Oxidation-Reduction; Phenobarbital; Proadifen; Pseudomonas; Rats; Spectrum Analysis

1972

Other Studies

16 other study(ies) available for proadifen and morphinans

ArticleYear
Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. II. Role of the type I drug-binding site of cytochrome P-450.
    Molecular pharmacology, 1973, Volume: 9, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Codeine; Cyanides; Cytochrome P-450 Enzyme System; Drug Synergism; Female; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Phospholipases; Proadifen; Protein Binding; Rats

1973
On the spectral intermediate at 440 nm formed during mixed function substrate oxidation.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Acetanilides; Aniline Compounds; Animals; Barbiturates; Cytochrome P-450 Enzyme System; Desipramine; Imipramine; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Proadifen; Protein Binding; Rats; Spectrophotometry, Ultraviolet

1974
Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats.
    Biochemical pharmacology, 1973, Dec-15, Volume: 22, Issue:24

    Topics: Aminopyrine; Aniline Compounds; Animals; Cobalt; Codeine; Edetic Acid; In Vitro Techniques; Iron; Kinetics; Lipid Metabolism; Lipids; Male; Manganese; Microsomes, Liver; Morphinans; Peroxides; Phenanthrolines; Proadifen; Rats

1973
Inhibition of microsomal drug metabolism by anticholinesterase insecticides.
    Bulletin of environmental contamination and toxicology, 1973, Volume: 9, Issue:1

    Topics: Aniline Compounds; Animals; Anisoles; Carbaryl; Cholinesterase Inhibitors; Hexobarbital; In Vitro Techniques; Insecticides; Kinetics; Malathion; Male; Microsomes, Liver; Morphinans; Oxidoreductases, N-Demethylating; Paraoxon; Parathion; Pharmaceutical Preparations; Proadifen; Rats; Sleep; Spectrophotometry; Time Factors; Zoxazolamine

1973
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Feb-08, Volume: 10, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation

1971
Inhibition of microsomal mixed-function oxidase activity with nicotinamide.
    Biochemical pharmacology, 1971, Volume: 20, Issue:8

    Topics: Animals; Azo Compounds; Biotransformation; Dealkylation; Depression, Chemical; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphinans; Niacinamide; Oxidoreductases; Proadifen; Rats

1971
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates

1969
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry

1969
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VI. Different substrate specificities of the cytochrome P450 fractions from control and phenobarbital-treated rats.
    The Journal of biological chemistry, 1973, Jan-25, Volume: 248, Issue:2

    Topics: Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Dealkylation; Dose-Response Relationship, Drug; Flavonoids; Hemeproteins; Hydroxylation; Lipids; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; Oxidoreductases, N-Demethylating; Pentobarbital; Phenobarbital; Piperazines; Proadifen; Rats; Structure-Activity Relationship; Testosterone

1973
In vitro activation of isophosphamide (NSC-109724), a new oxazaphosphorine, by rat liver microsomes.
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:5

    Topics: Alkylating Agents; Alkylation; Aminopyrine; Aniline Compounds; Animals; Cyclic P-Oxides; Cyclophosphamide; Dealkylation; DNA; Enzyme Activation; Ethylamines; Kinetics; Liver; Male; Microsomes, Liver; Morphinans; NADP; Oxazines; Oxidoreductases; Phenobarbital; Phosphoranes; Proadifen; Proteins; Rats; RNA

1972
Effects of dietary protein quality on drug metabolism in the rat.
    The Journal of nutrition, 1973, Volume: 103, Issue:10

    Topics: Anesthesia; Aniline Compounds; Animals; Body Weight; Caseins; Cytochrome P-450 Enzyme System; Dealkylation; Dietary Proteins; Drug Synergism; Glutens; Hexobarbital; Hydroxylation; Liver; Male; Microsomes, Liver; Morphinans; Organ Size; Phenobarbital; Proadifen; Proteins; Rats; Time Factors

1973
In vitro enhancement of aniline metabolism by paraoxon.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:2

    Topics: Acetone; Aniline Compounds; Animals; Dogs; Hexobarbital; Humans; Insecticides; Kinetics; Mice; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Nitrophenols; Paraoxon; Proadifen; Rabbits; Rats; Species Specificity; Stimulation, Chemical

1972
Studies on the transport of morphine into the cerebrospinal fluid of rabbits.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:1

    Topics: Animals; Biological Transport; Blood Proteins; Cerebral Ventricles; Chromatography, Thin Layer; Codeine; Dinitrophenols; Drug Tolerance; Glucuronates; Hydrogen-Ion Concentration; Ligation; Male; Morphinans; Morphine; Nalorphine; Naloxone; Proadifen; Protein Binding; Rabbits; Renal Veins; Tritium; Water

1972
Two-substrate kinetics of drug-metabolizing enzyme systems of hepatic microsomes.
    Molecular pharmacology, 1970, Volume: 6, Issue:3

    Topics: Alkylation; Aniline Compounds; Animals; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Stereoisomerism

1970
Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Animals; Benzene Derivatives; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Female; Formaldehyde; Kinetics; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Valerates

1969
Regulation of hepatobiliary excretion of sinomenine by P-glycoprotein in Sprague-Dawley rats.
    Life sciences, 2003, Apr-11, Volume: 72, Issue:21

    Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Microdialysis; Morphinans; Proadifen; Rats; Rats, Sprague-Dawley; Sinomenium; Specific Pathogen-Free Organisms

2003