proadifen has been researched along with methimazole in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Ruse, MJ; Waring, RH | 2 |
| Hanzlik, RP; Traiger, GJ; Vyas, KP | 1 |
| Kuroiwa, Y; Yamada, Y; Yamamoto, T; Yoshida, T | 1 |
| Kammerer, RC; Lampe, MA | 1 |
| Gooderham, NJ; Gorrod, JW | 1 |
| Paxton, JW; Robertson, IG; Schlemper, B; Siegers, DJ | 1 |
| Bland, TJ; Robertson, IG | 1 |
| Cha, YN; Chung, WG | 1 |
| Cha, YN; Chung, WG; Lee, WK; Park, CS; Roh, HK | 1 |
| Ha, H; Han, MY; Han, SS; Jeong, TC; Kim, EJ; Koh, WS; Lee, JW; Lee, M; Shin, KD | 1 |
| Damani, LA; Nnane, IP | 1 |
| Igarashi, K; Kasuya, F; Katagi, M; Nishikawa, M; Tsuchihashi, H; Tsutsumi, H | 1 |
14 other study(ies) available for proadifen and methimazole
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The S-oxidation of thioamides by rat liver microsomes.
Topics: Amines; Animals; Ethionamide; Kinetics; Male; Methimazole; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Rats, Inbred Strains | 1991 |
The effect of methimazole on thioamide bioactivation and toxicity.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Ethionamide; Liver; Male; Methimazole; Microsomes, Liver; Niacinamide; Organ Size; Proadifen; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Effect of inhibitors of alpha-naphthylisothiocyanate-induced hepatotoxicity on the in vitro metabolism of alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Aminopyrine; Animals; Bilirubin; Biotransformation; Chromatography, Gas; Ditiocarb; Ethionamide; Hyperbilirubinemia; Imidazoles; Kinetics; Male; Methimazole; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Thiocyanates | 1985 |
Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: relationship of metabolism to MAO-B inhibitory potency.
Topics: Amphetamine; Animals; Chromatography, Gas; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxylation; In Vitro Techniques; Male; Methamphetamine; Methimazole; Methylcholanthrene; Microsomes, Liver; Monoamine Oxidase Inhibitors; Phenethylamines; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Selegiline | 1986 |
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole | 1987 |
Routes to the formation of N-methyl-4-aminophenol, a metabolite of N,N-dimethylaniline.
Topics: Amines; Aminophenols; Aniline Compounds; Animals; Biotransformation; Carbon Monoxide; Guinea Pigs; Kinetics; Male; Methimazole; Microsomes, Liver; Polychlorinated Biphenyls; Proadifen; Structure-Activity Relationship; Superoxide Dismutase | 1981 |
Rat hepatocyte-mediated metabolism of the experimental anti-tumour agent N-[2'-(dimethylamino)ethyl]acridine-4-carboxamide.
Topics: Acridines; Aminoacridines; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Glucuronates; In Vitro Techniques; Liver; Male; Methimazole; Proadifen; Rats; Rats, Wistar | 1993 |
Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide.
Topics: Acridines; Acridones; Aldehyde Oxidase; Aldehyde Oxidoreductases; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cimetidine; Cytosol; Kinetics; Liver; Male; Methimazole; Metyrapone; Microsomes, Liver; NAD; Proadifen; Rats; Rats, Wistar | 1993 |
Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes.
Topics: Animals; Biotransformation; Caffeine; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Methimazole; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Proadifen; Rats; Rats, Sprague-Dawley; Species Specificity; Theobromine; Theophylline | 1997 |
Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.
Topics: Animals; Antithyroid Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Histamine H2 Antagonists; Humans; In Vitro Techniques; Isoenzymes; Male; Methimazole; Microsomes, Liver; Oxygenases; Proadifen; Ranitidine; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2000 |
Role of metabolism by flavin-containing monooxygenase in thioacetamide-induced immunosuppression.
Topics: Animals; Cell Division; Enzyme Inhibitors; Erythrocytes; Female; Immunoglobulin M; Immunosuppressive Agents; Interleukin-2; Lymphocytes; Methimazole; Mice; Mice, Inbred BALB C; Microsomes, Liver; Monoamine Oxidase; Proadifen; Sheep; Spleen; Thioacetamide | 2003 |
Involvement of cytochrome P450 and the flavin-containing monooxygenase(s) in the sulphoxidation of simple sulphides in human liver microsomes.
Topics: Chlorobenzenes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Humans; In Vitro Techniques; Methimazole; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Phenotype; Proadifen; Sulfides | 2003 |
In vitro confirmation of selegiline N-oxidation by flavin-containing monooxygenase in rat microsome using LC-ESI MS.
Topics: Amines; Animals; Antiparkinson Agents; Chromatography, Liquid; Enzyme Inhibitors; Heating; Hydrogen-Ion Concentration; In Vitro Techniques; Methimazole; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygenases; Proadifen; Rats; Selegiline; Spectrometry, Mass, Electrospray Ionization | 2004 |