proadifen has been researched along with methadone in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dalvie, D; Hu, Q; Jones, P; Obach, RS; Pryde, DC; Tran, TD | 1 |
| Kraus, JL; Yaouanc, JJ | 1 |
| Ho, TK; LaBella, FS; Pinsky, C | 1 |
| Franklin, MR; Roberts, SM | 1 |
| Bellward, GD; Gontovnick, LS; Ng, S | 1 |
| Covault, HP; Hostetler, RM; Peterson, GR | 1 |
| Bauer, J; Gerber, N; Gordon, P; Leger, RM; Lynn, RK; Smith, RG | 1 |
| Bertolatus, JA; Donald, AG; Hixson, B; Shah, NS | 1 |
| Bowman, ER; Brase, DA; Dewey, WL; Kachur, JF; Martin, BR; Rosemond, R; Welch, S | 1 |
| Harbison, RD; James, RC | 1 |
| Burkhalter, A; Masten, LW; Peterson, GR; Way, EL | 1 |
| Gamage, RS; Robertson, IG | 1 |
| ADLER, TK; VEATCH, RM; WAY, EL | 1 |
13 other study(ies) available for proadifen and methadone
| Article | Year |
|---|---|
Aldehyde oxidase: an enzyme of emerging importance in drug discovery.
Topics: Aldehyde Oxidase; Animals; Drug Discovery; Humans; Models, Molecular; Organ Specificity; Oxidation-Reduction; Pharmaceutical Preparations; Pharmacokinetics; Species Specificity; Substrate Specificity | 2010 |
Inhibition of the cytochrome P-450 multifunctional oxidase by N-propargyl analogs of SKF-525 A and acetylmethadol.
Topics: Aminopyrine N-Demethylase; Animals; Cytochrome P-450 Enzyme Inhibitors; Female; Flavins; Flavoproteins; Fluorometry; Kinetics; Male; Methadone; Methadyl Acetate; Mixed Function Oxygenases; Oxidoreductases; Proadifen; Rabbits; Rats; Time Factors | 1979 |
Opiate properties of SKF 525A.
Topics: Analgesia; Animals; Injections, Intraventricular; Male; Methadone; Morphine; Naloxone; Narcotics; Proadifen; Rats; Reaction Time; Receptors, Opioid | 1978 |
Modification of hepatic microsomal oxidative drug metabolism in rats by the opiate maintenance drugs acetylmethadol, propoxyphene, and methadone.
Topics: Animals; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Male; Methadone; Methadyl Acetate; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship | 1979 |
The irreversible binding of benzo[a]pyrene to rat liver macromolecules in vivo and in vitro: effects of agents that influence benzo[a]pyrene metabolism.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Cysteine; Enzyme Induction; Enzyme Inhibitors; Epoxide Hydrolases; Glutathione; In Vitro Techniques; Liver; Male; Methadone; Methylcholanthrene; Nucleic Acids; Proadifen; Protein Binding; Rats; Time Factors | 1979 |
Acute inhibition of microsomal drug metabolism by propoxyphene in narcotic tolerant/dependent mice.
Topics: Animals; Dextropropoxyphene; Drug Tolerance; Humans; Male; Methadone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Morphine Dependence; Oxidoreductases; Pentobarbital; Proadifen; Substance-Related Disorders | 1978 |
The metabolism of d-, l- and dl-methadone in the isolated perfused rat liver.
Topics: Animals; Biotransformation; Half-Life; Isomerism; Liver; Methadone; Perfusion; Phenobarbital; Proadifen; Rats | 1977 |
Tissue distribution of levo-methadone in nonpregnant and pregnant female and male mice: effect of SKF 525-A 1,2.
Topics: Animals; Dealkylation; Female; Fetus; Male; Methadone; Mice; Organ Specificity; Pregnancy; Proadifen; Stereoisomerism; Stimulation, Chemical; Time Factors | 1976 |
Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits.
Topics: Animals; Biological Assay; Dextrorphan; Diazepam; Dose-Response Relationship, Drug; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Levorphanol; Male; Meperidine; Methadone; Nociceptors; Pentazocine; Pentobarbital; Proadifen; Rabbits; Time Factors | 1985 |
Hepatic glutathione and hepatotoxicity: effects of cytochrome P-450 complexing compounds SKF 525-A, L-alpha acetylmethadol (LAAM), norLAAM, and piperonyl butoxide.
Topics: Alanine Transaminase; Animals; Cricetinae; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Mesocricetus; Methadone; Methadyl Acetate; Mice; Mixed Function Oxygenases; Piperonyl Butoxide; Proadifen; Rats; Rats, Inbred Strains | 1982 |
Tolerance to methadone lethality and microsomal enzyme induction in mice tolerant to and dependent on morphine.
Topics: Animals; Body Weight; Drug Tolerance; Enzyme Induction; Humans; Inactivation, Metabolic; Lethal Dose 50; Liver; Male; Methadone; Mice; Microsomes, Liver; Morphine; Morphine Dependence; Oxidoreductases, N-Demethylating; Proadifen | 1980 |
Methadone: a potent inhibitor of rat liver aldehyde oxidase.
Topics: Acridines; Acridones; Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Dextropropoxyphene; Liver; Methadone; Proadifen; Rats | 1994 |
THE IMPORTANCE OF STERIC CONFIGUA. ION IN CERTAIN MORPHINNE-MIMETIC ACTIONS OF SYNTHETIC ANALGETICS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Apnea; Chemical Phenomena; Chemistry; Methadone; Mice; Morphine; Nalorphine; Pain; Pharmacology; Proadifen; Research; Seizures; Toxicology | 1964 |