Compounds > proadifen
Page last updated: 2024-08-16

proadifen and diclofenac

proadifen has been researched along with diclofenac in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Iley, J; Mendes, E; Moreira, R; Souza, S1
Iwasaki, K; Kawashita, H; Masuda, N; Nagae, Y; Nakashima, A; Niina, M; Saxer, C1
Franklin, MR; Hathaway, LB1
Chen, M; Li, Y; Luan, Y; Qi, XM; Ren, J; Wu, XF; Wu, YF; Xing, GZ; Xue, X1

Other Studies

5 other study(ies) available for proadifen and diclofenac

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 9, Issue:2

    Topics: Amides; Animals; Benzoic Acid; Carboxylic Acids; Clofibric Acid; Diclofenac; Drug Interactions; Esters; Hydrolases; Hydrolysis; Ibuprofen; In Vitro Techniques; Liver; Male; Naproxen; Physostigmine; Proadifen; Probenecid; Prodrugs; Rats; Rats, Sprague-Dawley; Refractometry; Solubility; Structure-Activity Relationship; Time Factors; Valproic Acid

1999
Identification of cytochrome P450 forms involved in the 4-hydroxylation of valsartan, a potent and specific angiotensin II receptor antagonist, in human liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; Kinetics; Microsomes, Liver; Proadifen; Recombinant Proteins; Tetrazoles; Valine; Valsartan

2005
2-Diethylaminoethyl-2,2-diphenylvalerate-HCl (SKF525A) revisited: comparative cytochrome P450 inhibition in human liver microsomes by SKF525A, its metabolites, and SKF-acid and SKF-alcohol.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:12

    Topics: Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Microsomes, Liver; NADP; Proadifen; Valerates

2008
The relationship between diphenylamine structure and NSAIDs-induced hepatocytes injury.
    Toxicology letters, 2009, Apr-25, Volume: 186, Issue:2

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Diclofenac; Diphenylamine; Enzyme Inhibitors; Hepatocytes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; ortho-Aminobenzoates; Proadifen; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2009