Compounds > proadifen
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proadifen and debrisoquin

proadifen has been researched along with debrisoquin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Araki, J; Masubuchi, Y; Narimatsu, S; Suzuki, T1
Canoll, PD; Klein, M; Musacchio, JM1
Strecker, M; Wolff, T1

Other Studies

4 other study(ies) available for proadifen and debrisoquin

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
    Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12

    Topics: Animals; Biotransformation; Carbon Monoxide; Cysteine; Cytochrome P-450 Enzyme System; Debrisoquin; Dose-Response Relationship, Drug; Female; Glutathione; Lidocaine; Male; Microsomes, Liver; NADP; Oxygen; Proadifen; Propranolol; Proteins; Quinidine; Rats; Rats, Inbred Strains

1992
SKF 525-A and cytochrome P-450 ligands inhibit with high affinity the binding of [3H]dextromethorphan and sigma ligands to guinea pig brain.
    Life sciences, 1991, Volume: 48, Issue:6

    Topics: Animals; Binding, Competitive; Brain; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Dextromethorphan; Guinea Pigs; Kinetics; Ligands; Lobeline; Mixed Function Oxygenases; Neurotransmitter Uptake Inhibitors; Piperazines; Proadifen; Receptors, Opioid; Receptors, sigma; Sparteine

1991
Lack of relationship between debrisoquine 4-hydroxylation and other cytochrome P-450 dependent reactions in rat and human liver.
    Biochemical pharmacology, 1985, Aug-01, Volume: 34, Issue:15

    Topics: Animals; Cytochrome P-450 Enzyme System; Debrisoquin; Enzyme Induction; Female; Humans; Hydroxylation; Isoquinolines; Kinetics; Male; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity

1985