proadifen has been researched along with cimetidine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (60.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dalvie, D; Hu, Q; Jones, P; Obach, RS; Pryde, DC; Tran, TD | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Nishimura, H; Yamaguchi, K | 1 |
| Abernathy, CO; Bassan, H; Gillespie, J; Jacob, L; Lukacs, L; Zimmerman, HJ | 1 |
| Crouch, RK; el-Hage, A; Ferrans, VJ; Herman, EH; Yang, GC | 1 |
| DeMarco, GJ; Howard, PC; McCoy, GD | 1 |
| Duddy, SK; Hsia, MT | 1 |
| Amezcua, JL; Girón, E; Martinez-Tabche, L; Mourelle, M | 1 |
| Kuroiwa, Y; Misawa, S; Tanaka, E | 1 |
| Hall, ST; Houston, JB; Rhodes, JC | 1 |
| Cummings, AJ; Kaelin, AC | 1 |
| Christensen, JM; Parrott, KA | 1 |
| Margolis, S; Schwartz, MA | 1 |
| Bland, TJ; Robertson, IG | 1 |
| Berger, BJ; Cerami, A; Dai, WW; Paciorkowski, A | 1 |
| Doi, H; Horie, T; Iwasaki, H; Masubuchi, Y; Nishigaki, R | 1 |
| Taira, Z; Ueda, Y; Yamase, D | 1 |
| Choi, YH; Lee, JH; Lee, MG; Lee, U; Yang, KH | 1 |
| Ishihara, Y; Ishii, S; Onishi, Y; Sakai, Y; Shimamoto, N; Yamamura, N | 1 |
20 other study(ies) available for proadifen and cimetidine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Aldehyde oxidase: an enzyme of emerging importance in drug discovery.
Topics: Aldehyde Oxidase; Animals; Drug Discovery; Humans; Models, Molecular; Organ Specificity; Oxidation-Reduction; Pharmaceutical Preparations; Pharmacokinetics; Species Specificity; Substrate Specificity | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Angiotensin II-induced relaxation of fowl aorta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Aorta, Abdominal; Chickens; Cimetidine; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Indomethacin; Methysergide; Microscopy, Electron; Muscle, Smooth, Vascular; Ouabain; Proadifen; Propranolol; Pyrilamine; Vasodilation | 1988 |
Effects of H2-blocking agents on hepatocytes in vitro: correlation with potential for causing hepatic disease in patients.
Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cimetidine; Histamine H2 Antagonists; Humans; Imidazoles; Liver; Male; Proadifen; Ranitidine; Rats; Rats, Inbred Strains | 1986 |
Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice.
Topics: Alloxan; Animals; Blood Glucose; Chelating Agents; Cimetidine; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Hexobarbital; Hyperglycemia; Male; Mice; Mice, Inbred ICR; Piperazines; Proadifen; Razoxane; Sleep; Stereoisomerism; Superoxide Dismutase | 1986 |
Characterization of hamster liver nicotine metabolism. I. Relative rates of microsomal C and N oxidation.
Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Cotinine; Cricetinae; Cyanides; Cysteamine; Male; Mesocricetus; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nicotine; Oxidation-Reduction; Papain; Peptide Hydrolases; Proadifen | 1986 |
Cytoprotective effects of modulators of oxidative xenobiotic metabolism in precocene II-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzopyrans; Cell Survival; Chemical and Drug Induced Liver Injury; Cimetidine; Dose-Response Relationship, Drug; Insecticides; Male; Methylcholanthrene; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Plants; Proadifen; Rats; Rats, Inbred Strains | 1987 |
Cimetidine enhances and phenobarbital decreases parathion toxicity.
Topics: Animals; Cimetidine; Drug Synergism; Liver; Male; Parathion; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1986 |
Effects of cimetidine and diethylaminoethyl 2,2-diphenylvalerate HCL (SKF 525-A) on trimethadione metabolism in the rat.
Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme System; Dimethadione; Kinetics; Liver; Male; Oxazoles; Proadifen; Rats; Rats, Inbred Strains; Trimethadione | 1985 |
Inhibition of antipyrine metabolite formation in rats in vivo.
Topics: Animals; Antipyrine; Benzoflavones; Cimetidine; Cytochrome P-450 Enzyme System; Male; Metyrapone; Proadifen; Rats; Rats, Inbred Strains | 1984 |
A study of monooxygenase activity in human placental homogenates: in vitro behaviour towards a number of substrates and inhibitors.
Topics: 7-Alkoxycoumarin O-Dealkylase; Cimetidine; Female; Humans; Mixed Function Oxygenases; Oxazoles; Oxygenases; Placenta; Pregnancy; Proadifen | 1983 |
Influence of cimetidine on the disposition of ibuprofen in the rat.
Topics: Animals; Cimetidine; Drug Interactions; Gastric Mucosa; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Male; Models, Biological; Proadifen; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Effects of drugs and sterols on cholesterol 7 alpha-hydroxylase activity in rat liver microsomes.
Topics: Aminoglutethimide; Animals; Ascorbic Acid; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Cimetidine; Kinetics; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rats, Inbred Strains; Steroid Hydroxylases; Sterols | 1983 |
Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide.
Topics: Acridines; Acridones; Aldehyde Oxidase; Aldehyde Oxidoreductases; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cimetidine; Cytosol; Kinetics; Liver; Male; Methimazole; Metyrapone; Microsomes, Liver; NAD; Proadifen; Rats; Rats, Wistar | 1993 |
Synergism of cimetidine with anti-malarial agents.
Topics: Animals; Antimalarials; Chloroquine; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Heme; Histamine H2 Antagonists; Plasmodium falciparum; Polymers; Proadifen; Pyrimethamine | 1997 |
Chemiluminescence associated with the oxidative metabolism of salicylic acid in rat liver microsomes.
Topics: Animals; Biotransformation; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Kinetics; Luminescent Measurements; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Proadifen; Rats; Rats, Wistar; Salicylic Acid; Thiobarbituric Acid Reactive Substances | 2002 |
A new technique for assaying cytochrome P450 enzyme activity in a single cell.
Topics: Animals; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Hepatocytes; In Vitro Techniques; Male; Microscopy, Fluorescence; Oxazines; Proadifen; Rats; Rats, Wistar; Spectrometry, Fluorescence | 2007 |
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.
Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 Enzyme System; Diuretics; Drug Interactions; Enzyme Activators; Enzyme Inhibitors; Furosemide; Half-Life; Infusions, Intravenous; Injections, Intravenous; Isoniazid; Male; Methylcholanthrene; Orphenadrine; Proadifen; Quinine; Rats; Rats, Sprague-Dawley; Troleandomycin; Weight Gain | 2009 |
Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutathione; Ketoconazole; Lipid Peroxidation; Liver; Male; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Proadifen; Rats; Rats, Wistar; Substrate Cycling | 2011 |