proadifen has been researched along with chlorine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (78.95) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, RL; Hettrick, JM; Nigro, ND; Suppnick, JD | 1 |
| Bloch, RJ | 1 |
| Osswald, W; Viana, AP | 1 |
| Nakazawa, K | 1 |
| Kersting, D; Kersting, U; Spring, KR | 1 |
| Ross, SB | 1 |
| Martin, W; McIntosh, L; Nelli, S | 1 |
| Daveloose, D; Favier, A; Gonthier, B; Gürbay, A; Hincal, F | 1 |
| King, LJ; Parke, DV; Wolf, CR | 1 |
| Ahmad, S; Knowles, CO | 1 |
| Cucinell, SA; Dayton, PG; Perel, JM; Weiss, M | 1 |
| Bushing, JA; Sanders-Bush, E; Sulser, F | 1 |
| Carlson, GP; Fuller, GC | 1 |
| Hanson, HM; Porter, CC; Scriabine, A; Stone, CA; Torchiana, ML; Watson, LS | 1 |
| Mazel, P; Shargel, L | 1 |
| Kupfer, D; Levin, E | 1 |
| Fuller, RW; Molloy, BB; Roush, BW; Snoddy, HD | 1 |
| Fiserova-Bergerova, V | 1 |
| Berman, ML; Bochantin, J; Hagler, K; Lowe, HJ | 1 |
19 other study(ies) available for proadifen and chlorine
| Article | Year |
|---|---|
Rat liver microsome-mediated N-demethylation and mutagenicity of azoxymethane.
Topics: Animals; Azo Compounds; Azoxymethane; Benzoflavones; Biotransformation; Chlorides; Cobalt; Diet; Disulfiram; Formaldehyde; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats | 1978 |
Loss of acetylcholine receptor clusters induced by treatment of cultured rat myotubes with carbachol.
Topics: Animals; Calcium; Carbachol; Chlorides; Dose-Response Relationship, Drug; Fluphenazine; Lidocaine; Muscles; Potassium; Proadifen; Protease Inhibitors; Protein Conformation; Rats; Receptors, Cholinergic; Sodium | 1986 |
Antiarrhythmic effects of proadifen hydrochloride (SKF 525-A).
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Barbiturates; Barium; Blood Pressure; Bradycardia; Chlorides; Conjunctiva; Cornea; Depression, Chemical; Digitoxin; Dogs; Electrocardiography; Epinephrine; Heart Rate; Hydrochloric Acid; Hypotension; Imipramine; Irritants; Ouabain; Petroleum; Proadifen; Rabbits; Reflex | 1970 |
Studies on the demethylation, hydroxylation and N-oxidation of imipramine in rat liver.
Topics: Amino Alcohols; Animals; Carbon Isotopes; Chlorides; Chromatography, Paper; Dealkylation; Desipramine; Ethylamines; Imipramine; Liver; Magnesium; Male; Metabolism; Methylation; Oxidation-Reduction; Oxides; Phenobarbital; Proadifen; Rats; Valerates | 1970 |
Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells.
Topics: Absorption; Cell Line; Cell Membrane; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Hydrogen-Ion Concentration; Indomethacin; Ion Channels; Ketoconazole; Masoprocol; Membrane Potentials; Membrane Proteins; Proadifen; Thionucleotides; Transfection | 1993 |
Comparison of high affinity binding of 3H-proadifen and 3H-(-)-cocaine to rat liver membranes.
Topics: Alanine; Animals; Binding, Competitive; Cadmium; Cadmium Chloride; Chlorides; Cocaine; Liver; Male; Microsomes, Liver; Proadifen; Rats; Rats, Sprague-Dawley; Subcellular Fractions | 1995 |
Role of copper ions and cytochrome P450 in the vasodilator actions of the nitroxyl anion generator, Angeli's salt, on rat aorta.
Topics: Animals; Aorta; Chelating Agents; Chlorides; Copper Sulfate; Cuprizone; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Edetic Acid; Estradiol; Free Radical Scavengers; In Vitro Techniques; Male; Manganese Compounds; Nitric Oxide Donors; Nitrites; Oxidation-Reduction; Penicillamine; Phenanthrolines; Proadifen; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Azide; Superoxide Dismutase; Vasodilation | 2001 |
Microsomal metabolism of ciprofloxacin generates free radicals.
Topics: Animals; Antioxidants; Chlorides; Chromans; Ciprofloxacin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Free Radicals; Male; Microsomes, Liver; Oxidation-Reduction; Proadifen; Rats; Rats, Wistar; Zinc Compounds | 2001 |
Anaerobic dechlorination of trichlorofluoromethane by liver microsomal preparations in vitro.
Topics: Anaerobiosis; Animals; Carbon Tetrachloride; Chlorine; Cytochrome P-450 Enzyme System; Hydrocarbons, Fluorinated; Kinetics; Metyrapone; Microsomes, Liver; Oxygen; Partial Pressure; Proadifen; Rats; Time Factors | 1975 |
Metabolism of N'-(4-chloro-o-tolyl)-N,N-dimethylformamidine (chlorphenamidine) and 4'-chloro-o-formotoluidide by rat hepatic microsomal and soluble enzymes.
Topics: Amidines; Animals; Autoradiography; Carbon Isotopes; Chlorine; Formaldehyde; Hydrogen-Ion Concentration; In Vitro Techniques; Insecticides; Isoflurophate; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Proadifen; Rats; Time Factors; Toluene; Toluidines | 1971 |
Dose-dependence of drug plasma level decline in dogs.
Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K | 1967 |
p-Chloroamphetamine--inhibition of cerebral tryptophan hydroxylase.
Topics: Amphetamine; Animals; Brain Stem; Carbon Isotopes; Carboxy-Lyases; Chlorine; Chromatography, Ion Exchange; Dialysis; Enzyme Activation; Fenclonine; In Vitro Techniques; Kidney; Kinetics; Male; Methamphetamine; Mixed Function Oxygenases; Proadifen; Pteridines; Rats; Rats, Inbred Strains; Serotonin; Spectrometry, Fluorescence; Tryptophan | 1972 |
Interaction of modifiers of hepatic microsomal drug metabolism and the inhalation toxicity of 1,1-dichloroethylene.
Topics: Aerosols; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chlorine; Chromatography, Gas; Drug Interactions; Ethylamines; Glucose-6-Phosphatase; Hydrocarbons, Halogenated; Lung; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Phenobarbital; Proadifen; Rats; Time Factors | 1972 |
Some biochemical and pharmacological actions of (-) erythro-meta-(meta-chlorobenzyloxy)-2-(1-aminoethyl)-benzyl alcohol. A derivative of metaraminol.
Topics: Animals; Antihypertensive Agents; Avoidance Learning; Behavior, Animal; Benzyl Compounds; Blood Pressure; Chlorine; Dogs; Electric Stimulation; Ethers; Female; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Kinetics; Male; Metaraminol; Methyltyrosines; Mice; Myocardium; Norepinephrine; Phenyl Ethers; Proadifen; Rats; Synaptic Transmission; Time Factors; Tyramine | 1971 |
Influence of 2,4-dichloro-6-phenoxyethyl-amine (DPEA) and -diethylaminoethyl diphenylpropylacetate (SKF-525A) on hepatic microsomal azoreductase activity from phenobarbital or 3-methylcholanthrene induced rats.
Topics: Animals; Azo Compounds; Carbon Monoxide; Chlorine; Cytochromes; Enzyme Activation; Enzyme Induction; Ethylamines; Flavin Mononucleotide; Male; Methylcholanthrene; Microsomes, Liver; NADP; Naphthalenes; Nitrogen; Oxidoreductases; Phenobarbital; Phenols; Proadifen; Rats; Rats, Inbred Strains; Sulfonamides; Sulfonic Acids | 1972 |
Monooxygenase drug metabolizing activity in CaCl 2 -aggregated hepatic microsomes from rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Calcium Chloride; Carbon Monoxide; Chlorine; Dronabinol; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats | 1972 |
Further structure-activity studies on the lowering of brain 5-hydroxyindoles by 4-chloramphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Brain Chemistry; Carbon Isotopes; Chlorine; Dose-Response Relationship, Drug; Fluorometry; Hydroxyindoleacetic Acid; Indoles; Male; Mitochondria; Monoamine Oxidase Inhibitors; Phenethylamines; Proadifen; Rats; Serotonin; Structure-Activity Relationship | 1973 |
Changes of fluoride content in bone: an index of drug defluorination in vivo.
Topics: Anesthetics; Animals; Biotransformation; Body Weight; Bone and Bones; Chlorine; Drug Interactions; Ethanol; Ethers; Female; Fluoridation; Fluorides; Fluorine; Furans; Halothane; Hydrocarbons, Halogenated; Lethal Dose 50; Male; Methoxyflurane; Methyl Ethers; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Pregnancy; Proadifen; Rats; Time Factors | 1973 |
Uptake and elimination of methoxyflurane as influenced by enzyme induction in the rat.
Topics: Anesthesia, Inhalation; Animals; Chlorine; Drug Interactions; Enzyme Induction; Fluorides; Kidney; Liver; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Proadifen; Radioisotopes; Rats; Time Factors | 1973 |