proadifen has been researched along with carbon monoxide in 100 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 92 (92.00) | 18.7374 |
| 1990's | 7 (7.00) | 18.2507 |
| 2000's | 1 (1.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bachur, NR; Gee, M | 1 |
| Jonsson, J | 1 |
| Gillette, JR; Krishna, G; Sipes, IG | 1 |
| Dvorchik, BH; Hartman, RD; Marietta, MP; Vesell, ES; Weisz, J | 1 |
| Kraus, P | 1 |
| Dave, CV; Gurtoo, HL | 1 |
| Kawalek, JC; Lu, AY | 1 |
| Beckett, AH; Dajani, RM; Gorrod, JW | 1 |
| Dalezios, JI; Hsieh, DP; Krieger, RI; Salhab, AS | 1 |
| Roach, MK | 1 |
| Grudin, R; Moldèus, P; Orrenius, S; Vadi, H | 1 |
| Kappus, H; Remmer, H | 1 |
| Abreu-Greenberg, M; Busbee, DL; Cantrell, ET; Guyden, J | 1 |
| Ahokas, JT; Kärki, NT; Pelkonen, O | 1 |
| Ichihara, S; Sawahata, T; Watabe, T | 1 |
| McGowan, C; Sylvester, JT | 1 |
| Agosin, M; Capdevila, J; Naquira, C; Paulin, J | 1 |
| Berg, A; Carlstrom, K; Gustafsson, JA; Ingelman-Sundberg, M | 1 |
| Ackermann, E; Richter, K | 1 |
| McKillop, D; Powis, G | 2 |
| Agosin, M | 1 |
| Cooper, DY; Rosenthal, O; Schleyer, H; Thomas, JH; Vars, HM | 1 |
| Hammock, BD | 1 |
| Neal, RA; Norman, BJ | 1 |
| Helia, O; Pauliková, I | 1 |
| Araki, J; Masubuchi, Y; Narimatsu, S; Suzuki, T | 1 |
| Narimatsu, S; Watanabe, K; Yamamoto, I; Yoshimura, H | 1 |
| Adams, SP; Notides, AC | 1 |
| Cederbaum, AI; Krikun, G | 1 |
| Hayashi, S; Ishikawa, T; Murakami, K; Noshiro, M; Okuda, K; Shimosato, T | 1 |
| Freeman, JJ; Hayes, EP | 1 |
| Forkert, PG; Hofley, M; Racz, WJ | 1 |
| Smith, AG; Stewart, FP | 1 |
| Gram, TE; Okine, LK | 1 |
| Abraham, NG; Dunn, MW; Masferrer, J; McGiff, JC; Schwartzman, ML | 1 |
| Kuwahara, S; Mannering, GJ | 1 |
| Braun, AG; Harding, FA; Weinreb, SL | 1 |
| Wickramasinghe, SN | 1 |
| Inoue, T; Kishi, T; Niwaguchi, T; Suzuki, S; Yasuda, T | 1 |
| Freedman, RB; Nash, JA; Salmon, AG; Walklin, CM | 1 |
| Finnen, MJ; Shuster, S | 1 |
| Koransky, W; Vohland, HW | 1 |
| Delaissé, JM; Nyns, EJ | 1 |
| Bolt, HM; Kappus, H; Remmer, H | 2 |
| Coscia, CJ; Meehan, TD | 1 |
| Hellmer, KH; Tabarelli-Poplawski, S; Uehleke, H | 1 |
| Rane, A | 1 |
| Stawarz, RJ; Stitzel, RE | 1 |
| Douch, PG | 1 |
| Boulton, CA; Crabbe, MJ; Large, PJ | 1 |
| Inano, H; Tamaoki, BI | 1 |
| Siiteri, PK; Thompson, EA | 1 |
| Illing, HP; Netter, KJ | 1 |
| Gerhards, E | 1 |
| Akov, S; Borkovec, AB; Oliver, JE | 1 |
| Gigon, PL; Gillette, JR; Gram, TE | 1 |
| Gillette, JR; Sasame, HA | 1 |
| Ichiha, K; Kushunose, E; Kusunose, M | 1 |
| Ichihara, K; Kusunose, E; Kusunose, M | 1 |
| Creaven, PJ; Reese, WN; Roach, MK | 1 |
| Prough, RA; Reed, DJ; Wittkop, JA | 2 |
| Folsom, MD; Hodgson, E | 2 |
| Schechter, MS; Williamson, RL | 1 |
| Sawyer, BC; Slater, TF | 1 |
| Garner, JV; Garner, RC; Hanson, RS; Miller, EC; Miller, JA | 1 |
| Mattocks, AR; White, IN | 1 |
| Bickel, MH | 1 |
| Mazel, P; Shargel, L | 1 |
| Kupfer, D; Levin, E | 1 |
| Kaltiala, EH; Kärki, NT; Larmi, TK; Pelkonen, O | 1 |
| Hildebrandt, AG | 1 |
| Furukawa, T; Shigematsu, A; Takahashi, S | 1 |
| Dybing, E | 1 |
| Agosin, M; Capdevila, J; Morello, A; Perry, AS | 1 |
| Gustafsson, JA; Ingelman-Sundberg, M | 1 |
| Nichol, AW | 1 |
| Horie, T; Kitada, M; Kitagawa, H | 1 |
| Beije, B; Hultin, T | 1 |
| Casida, JE; Engel, JL; Matthews, HB; Skrinjarić-Spoljar, M | 1 |
| Kappas, A; Poland, A | 1 |
| Aust, SD; Pederson, TC | 1 |
| Mannering, GJ; Sladek, NE | 1 |
| Kimura, T; Kodama, M; Nagata, C; Nakayama, T | 1 |
| Johansen, T; Jørgensen, L | 1 |
| Gooderham, NJ; Gorrod, JW | 1 |
| Inoue, T; Murata, T; Niwaguchi, T | 1 |
| Porter, WR; Trager, WF; Wheeler, C | 1 |
| Latif, SA; McDermott, MJ; Morris, DJ | 1 |
| Hollenberg, PF; Koop, DR | 1 |
| Barber, PJ; Wilson, BJ | 1 |
| Anders, MW; Ratnayake, JH; Stevens, JL | 1 |
| Berger, BJ; Fairlamb, AH | 1 |
| Bennett, BM; McDonald, BJ | 1 |
| Brien, JF; Liu, Z; Marks, GS; McLaughlin, BE; Nakatsu, K | 1 |
| Cox, HH; Doddema, HJ; Faber, BW; Harder, W; Radhoe, H; Van Heiningen, WN | 1 |
| Archakov, AI; Karuzina, II; Lisitsa, AV; Petushkova, NA; Zgoda, VG | 1 |
2 review(s) available for proadifen and carbon monoxide
| Article | Year |
|---|---|
The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Ethylamines; Hydrogen-Ion Concentration; In Vitro Techniques; Isocitrate Dehydrogenase; Methylation; Metyrapone; Microsomes, Liver; Morphinans; Oxidation-Reduction; Phenobarbital; Proadifen; Pseudomonas; Rats; Spectrum Analysis | 1972 |
[Role of cytochrome P-450 in mixed function oxidation and metabolism of anesthetics].
Topics: Anesthetics; Animals; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Transport; Enzyme Induction; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Proadifen | 1974 |
98 other study(ies) available for proadifen and carbon monoxide
| Article | Year |
|---|---|
Microsomal reductive glycosidase.
Topics: Animals; Anti-Bacterial Agents; Carbon Monoxide; Daunorubicin; Glycoside Hydrolases; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; Oxygen; Proadifen; Rats; Sulfhydryl Reagents | 1976 |
On the aromatic hydroxylation of amphetamine in rat liver microsomes and perfused liver preparations: effects of long-term administration.
Topics: Administration, Oral; Amphetamines; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Desipramine; Fenfluramine; Hydroxylation; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Perfusion; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Time Factors | 1977 |
Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: role of cytochrome P-450.
Topics: Allylisopropylacetamide; Animals; Bromotrichloromethane; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Glutathione; Immune Sera; In Vitro Techniques; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Nitrogen; Proadifen; Protein Binding; Rats | 1977 |
Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: comparison with hepatic aminopyrine N-demethylation.
Topics: Aminopyrine N-Demethylase; Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Brain; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Male; Meperidine; Microsomes; Microsomes, Liver; NAD; NADP; Proadifen; Proteins; Rats | 1979 |
Biodegradation of alpha-hexachlorocyclohexane. VI. The cechlorination of alpha-hexachlorocyclohexane by microsomes and cytosol of rat liver.
Topics: Acetone; Animals; Biodegradation, Environmental; Carbon Monoxide; Cytosol; Female; Glutathione; Hexachlorocyclohexane; Liver; Microsomes, Liver; NADP; Proadifen; Rats; Sulfobromophthalein | 1975 |
In vitro metabolic conversion of aflatoxins and benzo(alpha)pyrene to nucleic acid-binding metabolites.
Topics: Aflatoxins; Animals; Benzopyrenes; Carbon Monoxide; Cell Fractionation; DNA; Liver; Methylcholanthrene; Micrococcus; Microsomes, Liver; NADP; Nitrogen; Nucleic Acid Denaturation; Phenobarbital; Proadifen; Rats; RNA; RNA, Transfer; Spectrum Analysis; Thymus Gland; Tritium | 1975 |
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VIII. Different catalytic activities of rabbit and rat cytochromes P-448.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochrome Reductases; Cytochromes; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Pharmaceutical Preparations; Proadifen; Rabbits; Rats | 1975 |
In vitro hepatic and extra-hepatic reduction of (minus)-nicotine-1'-N-oxide in rats.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Chromatography, Gas; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Digestive System; Duodenum; Edetic Acid; Flavins; Gastric Mucosa; Ileum; In Vitro Techniques; Intestines; Kidney; Kinetics; Liver; Lung; Male; Microsomes; Microsomes, Liver; Mitochondria, Liver; Myocardium; NADH, NADPH Oxidoreductases; NADP; Nicotine; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Proadifen; Proteins; Rats | 1975 |
Aflaxation B1 hydroxylation by hepatic microsomal preparations from the rhesus monkey.
Topics: Aflatoxins; Animals; Biotransformation; Carbon Monoxide; Hydrogen-Ion Concentration; Hydroxylation; In Vitro Techniques; Macaca mulatta; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Proadifen; Time Factors | 1975 |
Microsomal ethanol oxidation: activity in vitro and in vivo.
Topics: Animals; Azides; Carbon Monoxide; Catalase; Cyanides; Ethanol; Hydrogen Peroxide; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Pyrazoles; Rats | 1975 |
Drug metabolism in isolated rat liver cells.
Topics: Alprenolol; Animals; Biotransformation; Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fasting; Glucose; Glucuronates; Imipramine; Lactates; Liver; Methods; Metyrapone; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Protein Binding; Rats; Rotenone; Spectrum Analysis; Temperature; Tritium | 1975 |
Irreversible protein binding of [14-C]imipramine with rat and human liver microsomes.
Topics: Animals; Carbon Monoxide; Cattle; Cytochrome P-450 Enzyme Inhibitors; Epoxide Hydrolases; Humans; Imipramine; In Vitro Techniques; Male; Microsomes, Liver; NADP; Proadifen; Protein Binding; Rats; Rifampin; Serum Albumin, Bovine; Sulfhydryl Compounds; Time Factors | 1975 |
Metabolism of diphenyloxazole (PPO) by mouse liver microsomes.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carbon Monoxide; Depression, Chemical; Enzyme Induction; Flavonoids; Kinetics; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxazoles; Proadifen | 1975 |
Characterization of benzo(a)pyrene hydroxylase of trout liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Proadifen; Rats; Salmonidae; Trout | 1977 |
Hepatic microsomal biotransformation of 1,3,5(10),16-estratetraen-3-o1 to 16,17-epiestriol and estriol via 16 alpha,17 alpha- and 16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ols.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Epoxy Compounds; Estrenes; Estriol; Female; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metyrapone; Microsomes, Liver; Proadifen; Rats; Stereoisomerism | 1979 |
The effects of agents that bind to cytochrome P-450 on hypoxic pulmonary vasoconstriction.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Extracorporeal Circulation; Hypoxia; Lung; Metyrapone; Muscle, Smooth; Proadifen; Prostaglandins F; Swine; Vasoconstriction | 1978 |
Cytochrome P-450 and drug metabolism in Trypanosoma cruzi: effects of phenobarbital.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Cytochrome P-450 Enzyme System; Metyrapone; Microsomes; Mixed Function Oxygenases; Oxidoreductases, O-Demethylating; Phenobarbital; Proadifen; Ribosomes; Trypanosoma cruzi | 1976 |
Demonstration of a cytochrome P-450-dependent steroid 15beta-hydroxylase in Bacillus megaterium.
Topics: Bacillus megaterium; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Imidazoles; Kinetics; Metyrapone; Multienzyme Complexes; Proadifen; Progesterone; Protein Binding; Steroid Hydroxylases | 1975 |
Dizepam metabolism in human foetal and adult liver.
Topics: Aging; Carbon Monoxide; Dealkylation; Depression, Chemical; Diazepam; Female; Fetus; Gestational Age; Humans; Hydroxylation; In Vitro Techniques; Liver; Microsomes, Liver; Pregnancy; Proadifen; Spectrophotometry; Time Factors | 1977 |
The metabolism and binding of catecholamines by the hepatic microsomal mixed-function oxidase of the rat.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Epinephrine; Hydroxybenzoates; Kinetics; Microsomes, Liver; Monoamine Oxidase Inhibitors; NADH, NADPH Oxidoreductases; Norepinephrine; Oxygen Consumption; Proadifen; Rats; Triazoles | 1976 |
Insect cytochrome P-450.
Topics: Animals; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Houseflies; Membranes; Microsomes; Naphthalenes; Phenobarbital; Proadifen; Protein Binding; Spectrophotometry; Subcellular Fractions | 1976 |
The metabolism and binding of catecholamines by the hepatic microsomal fraction of the rat.
Topics: Aerobiosis; Anaerobiosis; Animals; Binding Sites; Carbon Monoxide; Epinephrine; Microsomes, Liver; Norepinephrine; Pargyline; Proadifen; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet | 1976 |
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Photochemistry; Polycyclic Compounds; Proadifen; Rats; Spectrum Analysis; Time Factors | 1975 |
NADPH dependent epoxidation of methyl farnesoate to juvenile hormone in the cockroach Blaberus giganteus L.
Topics: Animals; Carbon Monoxide; Cockroaches; Depression, Chemical; Endocrine Glands; Epoxy Compounds; Fatty Acids, Unsaturated; Female; Juvenile Hormones; Methylene Blue; Microsomes; NADH, NADPH Oxidoreductases; Neurosecretory Systems; Piperonyl Butoxide; Proadifen; Sesquiterpenes; Solubility | 1975 |
Examination of the metabolism in vitro of parathion (diethyl p-nitrophenyl phosphorothionate) by rat lung and brain.
Topics: Aerobiosis; Anaerobiosis; Animals; Brain; Carbon Monoxide; In Vitro Techniques; Kinetics; Lung; Male; Paraoxon; Parathion; Proadifen; Rats; Subcellular Fractions | 1976 |
Rat hepatic microsomal metabolism of oxyprothepine: the role of inhibitors on S-oxygenation.
Topics: Animals; Antimetabolites; Carbon Monoxide; Dibenzothiepins; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Proadifen; Rats; Rats, Inbred Strains | 1992 |
Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
Topics: Animals; Biotransformation; Carbon Monoxide; Cysteine; Cytochrome P-450 Enzyme System; Debrisoquin; Dose-Response Relationship, Drug; Female; Glutathione; Lidocaine; Male; Microsomes, Liver; NADP; Oxygen; Proadifen; Propranolol; Proteins; Quinidine; Rats; Rats, Inbred Strains | 1992 |
Hepatic microsomal oxygenation of aldehydes to carboxylic acids.
Topics: Aldehydes; Animals; Carbon Monoxide; Carboxylic Acids; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Oxidation-Reduction; Proadifen | 1990 |
Reduction of irreversible binding of diethylstilbestrol in hamster renal cortex by inhibitors of cytochrome P-450.
Topics: Animals; Butylated Hydroxytoluene; Carbon Monoxide; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System; Dicumarol; Dienestrol; Diethylstilbestrol; Isoenzymes; Kidney Cortex; Male; Metyrapone; Microsomes, Liver; Proadifen; Time Factors | 1987 |
Evaluation of microsomal pathways of oxidation of alcohols and hydroxyl radical scavenging agents with carbon monoxide and cobalt protoporphyrin IX.
Topics: Alcohols; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Porphyrins; Proadifen; Protoporphyrins; Rats; Rats, Inbred Strains; Superoxides | 1985 |
Aryl hydrocarbon hydroxylase activity in rat submandibular glands.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Metyrapone; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Submandibular Gland; Time Factors | 1986 |
Microsomal metabolism of acetonitrile to cyanide. Effects of acetone and other compounds.
Topics: Acetone; Acetonitriles; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Ethanol; Female; Metyrapone; Microsomes, Liver; NAD; Proadifen; Proteins; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes.
Topics: Animals; Biotransformation; Carbon Monoxide; Dichloroethylenes; Hydrocarbons, Chlorinated; Lung; Male; Mice; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Piperonyl Butoxide; Proadifen | 1987 |
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole | 1986 |
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions | 1986 |
Cytochrome P450 dependent metabolism of arachidonic acid in bovine corneal epithelium.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cattle; Chromatography, Thin Layer; Cornea; Cytochrome P-450 Enzyme System; Epithelium; Microsomes; NADP; Proadifen | 1985 |
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats | 1985 |
Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450.
Topics: Amines; Animals; Biotransformation; Carbon Monoxide; Catalase; Cytochrome P-450 Enzyme System; Dogs; In Vitro Techniques; Isoenzymes; Microsomes, Liver; NADP; Proadifen; Spectrophotometry; Superoxide Dismutase; Thalidomide | 1986 |
Observations on the biochemical basis of ethanol metabolism by human macrophages.
Topics: Amitrole; Carbon Monoxide; Catalase; Cell Survival; Cells, Cultured; Ethanol; Humans; Macrophages; Metyrapone; NADP; Proadifen; Pyrazoles | 1986 |
The metabolism of 1-phenyl-2-(N-methyl-N-furfurylamino)propane (furfenorex) in the rat in vivo and in vitro.
Topics: Animals; Appetite Depressants; Biotransformation; Carbon Monoxide; Chromatography, Gas; Chromatography, Thin Layer; Furans; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Spectrophotometry | 1986 |
Dechlorination of halocarbons by microsomes and vesicular reconstituted cytochrome P-450 systems under reductive conditions.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ethane; Hydrocarbons, Chlorinated; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Oxidation-Reduction; Proadifen; Rabbits; Rats | 1985 |
Phase 1 and Phase 2 drug metabolism in isolated epidermal cells from adult hairless mice and in whole human hair follicles.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Epidermis; Female; Hair; Humans; Kinetics; Male; Mice; Mice, Hairless; Proadifen; Spectrometry, Fluorescence; Umbelliferones | 1985 |
Effect of -hexachlorocyclohexane on metabolism and excretion of pentetrazol (cardiazol) in the rat.
Topics: Animals; Anticonvulsants; Brain; Carbon Monoxide; Female; Half-Life; Haplorhini; Hexachlorocyclohexane; Microsomes, Liver; NADP; Oxidoreductases; Oxygen; Pentylenetetrazole; Proadifen | 1972 |
Detection of cytochrome P-450 in subcellular fractions of Endomycopsislipolytica grown on n-hexadecane.
Topics: Alkanes; Ascomycota; Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucose; Metyrapone; Mixed Function Oxygenases; Oxidation-Reduction; Proadifen; Spectrophotometry; Subcellular Fractions; Ultracentrifugation | 1974 |
Irreversible protein binding of metabolites of ethynylestradiol in vivo and in vitro.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Charcoal; Chromatography, Gel; Chromatography, Ion Exchange; Endoplasmic Reticulum; Estradiol; Ethinyl Estradiol; Female; Hydroxylation; Male; Microsomes, Liver; NADP; Peptide Fragments; Phenobarbital; Proadifen; Protein Binding; Proteins; Rats; Serum Albumin, Bovine; Time Factors; Tritium; Trypsin | 1973 |
Hydroxylation of geraniol and nerol by a monooxygenase from Vinca rosea.
Topics: Alcohols; Azides; Carbon Monoxide; Chromatography, Thin Layer; Cyanides; Hydroxylation; Microsomes; NADP; Oxidoreductases; Plant Cells; Plants; Proadifen; Terpenes; Tritium | 1973 |
Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Glutathione; Halothane; In Vitro Techniques; Kidney; Lung; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Proadifen; Protein Binding; Rabbits; Spectrophotometry; Sulfites | 1973 |
N-oxidation of a tertiary amine (N,N-dimethylaniline) by human fetal liver microsomes.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Chromatography, Paper; Dimethylamines; Female; Fetus; Gestational Age; Humans; Kinetics; Liver; Male; Microsomes, Liver; Middle Aged; NADP; Nitrogen Oxides; Oxidation-Reduction; Proadifen; Rats | 1974 |
Studies on the metabolism of ethynylestradiol in vitro and in vivo: the significance of 2-hydroxylation and the formation of polar products.
Topics: Animals; Carbon Monoxide; Chromatography; Chromatography, Thin Layer; Estradiol; Estrone; Ethinyl Estradiol; Glutathione; Hydroxylation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Rats; Silicon Dioxide; Spectrophotometry, Ultraviolet; Tritium | 1973 |
Factors influencing the microsomal metabolism of 3H-reserpine.
Topics: Animals; Benzoates; Biotransformation; Carbon Monoxide; Cats; Chromatography, Thin Layer; Depression, Chemical; Dogs; Enzyme Induction; Female; Formaldehyde; Guinea Pigs; Hydrogen-Ion Concentration; Hydrolysis; Liver; Male; Methylcholanthrene; Microsomes, Liver; NAD; NADH, NADPH Oxidoreductases; NADP; Phenobarbital; Proadifen; Rats; Reserpine; Stimulation, Chemical; Temperature | 1974 |
The metabolism of some thioureidobenzene fungicides in mice and sheep.
Topics: Animals; Benzene Derivatives; Benzimidazoles; Brain; Carbamates; Carbon Monoxide; Chromatography; Chromatography, Thin Layer; Crystallization; Feces; Fungicides, Industrial; Glucuronates; Glucuronidase; Intestinal Mucosa; Kidney; Liver; Male; Mice; NADP; Organ Specificity; Oxidation-Reduction; Phenylthiourea; Proadifen; Sheep; Silicon Dioxide; Species Specificity; Structure-Activity Relationship; Sulfatases; Sulfuric Acids; Thiourea | 1974 |
Microbial oxidation of amines. Partial purification of a trimethylamine mono-oxygenase from Pseudomonas aminovorans and its role in growth on trimethylamine.
Topics: Amines; Carbon Monoxide; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyanides; Hydrogen-Ion Concentration; Methylamines; NADP; Onium Compounds; Oxygenases; Potassium; Proadifen; Pseudomonas; Quaternary Ammonium Compounds; Spectrophotometry; Sulfides; Sulfonium Compounds; Ultrasonics | 1974 |
Steroid 7 alpha-hydroxylase of rat testes.
Topics: Androstanes; Aniline Compounds; Animals; Carbon Monoxide; Cell Fractionation; Chloromercuribenzoates; Cytochromes; Dehydroepiandrosterone; Edetic Acid; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Indenes; Male; Microsomes; Mixed Function Oxygenases; Naphthalenes; Proadifen; Pyridines; Radiation Effects; Rats; Temperature; Testis; Testosterone; Time | 1971 |
The involvement of human placental microsomal cytochrome P-450 in aromatization.
Topics: Aminoglutethimide; Androstenedione; Animals; Binding Sites; Binding, Competitive; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Humans; Kinetics; Metyrapone; Microsomes; Microsomes, Liver; Nandrolone; Placenta; Pregnancy; Proadifen; Protein Binding; Rabbits; Receptors, Cell Surface; Spectrophotometry; Spectrophotometry, Ultraviolet; Steroids; Swine; Tritium | 1974 |
Kinetic experiments on the synergistic effect of NADH on microsomal drug oxidation.
Topics: Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Chloromercuribenzoates; Drug Synergism; Hexobarbital; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NAD; Nitro Compounds; Oxidation-Reduction; Oxygen Consumption; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenols; Proadifen; Pyridines; Rats; Spectrophotometry | 1974 |
[On 2-benzolsulfonylamino-5 (beta-methoxyethoxy) pyrimidine (Glycodiazin). VII. On the mechanism of demethylation of Glycodiazin].
Topics: Animals; Buffers; Carbon Monoxide; Cyanides; Cytoplasm; Edetic Acid; Hydrogen-Ion Concentration; Hypoglycemic Agents; Kidney; Liver; Male; Metals; Microsomes; NADP; Oxygen; Phenanthrolines; Potassium; Proadifen; Rats; Sulfonamides | 1968 |
N-demethylation of the chemosterilant HEMPA by ouse fly microscomes.
Topics: Animals; Carbon Monoxide; Chemosterilants; Houseflies; In Vitro Techniques; Insect Control; Microsomes; NADP; Oxygen; Phosphoric Acids; Proadifen; Rats; Serum Albumin, Bovine | 1968 |
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates | 1969 |
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry | 1969 |
Some properties and distribution of the omega-hydroxylation system of medium-chain fatty acids.
Topics: Animals; Anura; Carbon Isotopes; Carbon Monoxide; Cattle; Chromatography, Gas; Chromatography, Thin Layer; Columbidae; Cyanides; Cyprinidae; Cytochromes; Dogs; Fatty Acids; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lung; Male; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Proadifen; Rabbits; Rats; Salts; Species Specificity; Swine | 1969 |
Microsomal hydroxylation of decane.
Topics: Alcohols; Alkanes; Aniline Compounds; Animals; Carbon Isotopes; Carbon Monoxide; Cattle; Chick Embryo; Columbidae; Cyanides; Fatty Acids; Glycols; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lung; Male; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Phenobarbital; Proadifen; Rabbits; Rats | 1969 |
Ethanol oxidation in the microsomal fraction of rat liver.
Topics: Acetaldehyde; Animals; Azides; Biphenyl Compounds; Carbon Monoxide; Catalase; Cattle; Cyanides; Cytochromes; Depression, Chemical; Ethanol; Glucose; Glucose Oxidase; Liver; Male; Microsomes; NADP; Peroxides; Proadifen; Rats; Stimulation, Chemical; Triazoles | 1969 |
Oxidative demethylation of N-methylhydrazines by rat liver microsomes.
Topics: Animals; Azo Compounds; Bile Acids and Salts; Carbon Monoxide; Cytochromes; Formaldehyde; Hot Temperature; Hydrazines; In Vitro Techniques; Lipase; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen Consumption; Pancreatic Juice; Phenobarbital; Proadifen; Rats | 1969 |
Biochemical characteristics of insect microsomes: NADPH oxidation by intact microsomes from the housefly, Musca domestica.
Topics: Animals; Carbon Monoxide; Chloromercuribenzoates; Copper; Cyanides; Cytochromes; Depression, Chemical; Ethylmaleimide; Female; Houseflies; Iodoacetates; Kinetics; Male; Microsomes; NAD; NADP; Oxidoreductases; Proadifen; Pyridines; Pyrroles; Stimulation, Chemical; Sulfhydryl Compounds; Zinc | 1970 |
Microsomal epoxidation of aldrin in lepidopterous larvae.
Topics: Aerobiosis; Animals; Ascorbic Acid; Carbon Monoxide; Cattle; Chromatography, Gas; Cyanides; Cytochromes; Dieldrin; Edetic Acid; Ethers, Cyclic; Hydrocarbons, Halogenated; Insecta; Insecticides; Kinetics; Larva; Microsomes; NADP; Naphthalenes; Niacinamide; Oxidation-Reduction; Potassium; Proadifen; Serum Albumin, Bovine; Species Specificity; Spectrophotometry; Ultracentrifugation; Urea; Valerates | 1970 |
Oxygen uptake by microsomal preparations from the housefly, Musca domestica.
Topics: Animals; Anisoles; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Dioxoles; Houseflies; Hydrogen-Ion Concentration; Kinetics; Mercury; Microsomes; NAD; NADP; Nitro Compounds; Organometallic Compounds; Oxygen Consumption; Polarography; Potassium; Proadifen; Sulfhydryl Reagents; Sulfonic Acids; Sulfoxides | 1971 |
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Interaction sites in the endoplasmic reticulum.
Topics: Aldehydes; Aminopyrine; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloromercuribenzoates; Cytochromes; Electron Transport; Endoplasmic Reticulum; In Vitro Techniques; Lipid Metabolism; Liver; Malonates; Microsomes, Liver; NADP; Niacinamide; Peroxides; Proadifen; Rats | 1971 |
Formation of a factor lethal for S. typhimurium TA1530 and TA1531 on incubation of aflatoxin B 1 with rat liver microsomes.
Topics: Aflatoxins; Aniline Compounds; Animals; Carbon Monoxide; Caseins; Chromatography, Thin Layer; Depression, Chemical; Diet; Male; Microsomes, Liver; NADP; Nitrogen; Oxygen Consumption; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1971 |
The conversion of pyrrolizidine alkaloids to N-oxides and to dihydropyrrolizine derivatives by rat-liver microsomes in vitro.
Topics: Alkaloids; Animals; Calcium; Carbon Monoxide; DDT; Diet; Kinetics; Lung; Magnesium; Manganese; Microsomes; Microsomes, Liver; Models, Biological; NADP; Niacinamide; Oxides; Oxygen; Phenobarbital; Proadifen; Proteins; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1971 |
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. I. Tricyclic tertiary amine drugs.
Topics: Amitriptyline; Animals; Carbon Isotopes; Carbon Monoxide; Chlorpromazine; Cyclic N-Oxides; Cytochromes; Dealkylation; Desipramine; Horses; Imipramine; Kinetics; Liver; Male; NADP; Organ Specificity; Oxidation-Reduction; Proadifen; Rats; Species Specificity; Subcellular Fractions; Swine; Tetrazolium Salts | 1972 |
Influence of 2,4-dichloro-6-phenoxyethyl-amine (DPEA) and -diethylaminoethyl diphenylpropylacetate (SKF-525A) on hepatic microsomal azoreductase activity from phenobarbital or 3-methylcholanthrene induced rats.
Topics: Animals; Azo Compounds; Carbon Monoxide; Chlorine; Cytochromes; Enzyme Activation; Enzyme Induction; Ethylamines; Flavin Mononucleotide; Male; Methylcholanthrene; Microsomes, Liver; NADP; Naphthalenes; Nitrogen; Oxidoreductases; Phenobarbital; Phenols; Proadifen; Rats; Rats, Inbred Strains; Sulfonamides; Sulfonic Acids | 1972 |
Monooxygenase drug metabolizing activity in CaCl 2 -aggregated hepatic microsomes from rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Calcium Chloride; Carbon Monoxide; Chlorine; Dronabinol; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats | 1972 |
Cytochrome P-450-linked monooxygenase system and drug-induced spectral interactions in human liver microsomes.
Topics: Amines; Aniline Compounds; Animals; Antimetabolites; Benzene Derivatives; Butanols; Carbon Monoxide; Cholelithiasis; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Guinea Pigs; Hexobarbital; Humans; Liver; Microsomes, Liver; Oxygenases; Phenacetin; Proadifen; Rabbits; Rats; Smoking; Species Specificity; Spectrophotometry | 1974 |
Microsomal drug oxidation. Function, induction, and inhibition of the cytochrome P450-system.
Topics: Animals; Benzopyrenes; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Depression, Chemical; Enzyme Induction; Humans; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Proadifen; Rabbits; Rats; Spectrophotometry | 1973 |
Some spectral properties of cytochrome P-450 from microsomes isolated from control, phenobarbital- and naphthalene-treated houseflies.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Houseflies; Ligands; Microsomes; Naphthalenes; Nucleic Acid Conformation; Phenobarbital; Proadifen; Protein Conformation; Spectrophotometry; Spectrophotometry, Ultraviolet | 1973 |
Regulation and properties of a sex-specific hydroxylase system in female rat liver microsomes active on steroid sulfates. I. General characteristics.
Topics: Age Factors; Androstanes; Animals; Carbon Monoxide; Carbon Radioisotopes; Castration; Estradiol; Female; Hydroxysteroids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rats; Sex Factors; Steroid Hydroxylases; Sulfuric Acids; Testosterone | 1974 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
Studies on drug metabolism. 13. Possible role of liver microsomal cytochrome P-450 in the oxidative N-demethylation of p-substituted dimethylaniline, N-methyl-N-alkylaniline and N-methyl-N-acylaniline derivatives.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Male; Methylation; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1972 |
Oxidation and protein binding of aromatic amines by rat liver microsomes.
Topics: Amines; Aniline Compounds; Animals; Bile Acids and Salts; Carbon Isotopes; Carbon Monoxide; Cytochromes; Fluorenes; Male; Microsomes, Liver; Oxidation-Reduction; Proadifen; Protein Binding; Rats; Rats, Inbred Strains; Sulfhydryl Reagents; Trypsin | 1971 |
Response of hepatic microsomal mixed-function oxidases to various types of insecticide chemical synergists administered to mice.
Topics: Alkynes; Aniline Compounds; Animals; Anisoles; Benzopyrans; Carbamates; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dimethyl Sulfoxide; Dioxoles; Drug Synergism; Enzyme Induction; Ethers; Hexobarbital; Hydrocarbons, Halogenated; Hydroxylation; In Vitro Techniques; Indoles; Insecticides; Male; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidoreductases; Pesticide Synergists; Pesticides; Piperonyl Butoxide; Proadifen; Pyrazoles; Rotenone; Sleep; Spectrophotometry; Sulfites; Thiadiazoles; Time Factors | 1971 |
The metabolism of aminopyrine in chick embryo hepatic cell culture: effects of competitive substrates and carbon monoxide.
Topics: Aminopyrine; Animals; Antipyrine; Carbon Monoxide; Cells, Cultured; Chick Embryo; Dealkylation; Fatty Acids; Hexobarbital; Intestinal Mucosa; Kidney; Kinetics; Liver; Oxygen Consumption; Piperonyl Butoxide; Proadifen; Testosterone | 1971 |
Further evidene on the nature of microsomal metabolism of procarbazine and related alkyhydrazines.
Topics: Animals; Benzoates; Carbon Monoxide; Cytochromes; Enzyme Induction; Hydrazines; Male; Methylcholanthrene; Microsomes, Liver; Nitrogen; Oxidoreductases; Oxygen; Phenobarbital; Proadifen; Rats; Sheep; Swine; Trypsin | 1970 |
Aminopyrine demethylase. Kinetic evidence for multiple microsomal activities.
Topics: Aminopyrine; Animals; Carbon Monoxide; Chromatography, Thin Layer; Cytochromes; Dealkylation; Enzyme Induction; Ethionine; Goats; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Proadifen; Rats; Spectrophotometry; Stimulation, Chemical; Sulfites | 1970 |
Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.
Topics: Animals; Benzene Derivatives; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Female; Formaldehyde; Kinetics; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Valerates | 1969 |
Electron spin resonance study on the metabolism of 2-naphthylamine and 1-naphthylamine in rat liver microsomes.
Topics: 1-Naphthylamine; 2-Naphthylamine; Animals; Biotransformation; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Free Radicals; Male; Microsomes, Liver; Naphthalenes; Proadifen; Rats; Rats, Inbred Strains | 1982 |
Affinity of drugs for cytochrome P-450 determined by inhibition of p-nitrophenetole O-deethylation by rat liver microsomes.
Topics: Animals; Biotransformation; Carbon Monoxide; Chloramphenicol; Cytochrome P-450 Enzyme System; Disulfiram; Drug Interactions; Isoniazid; Kinetics; Male; Microsomes, Liver; Nitrobenzenes; Nitrophenols; Oxidation-Reduction; Phenytoin; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Routes to the formation of N-methyl-4-aminophenol, a metabolite of N,N-dimethylaniline.
Topics: Amines; Aminophenols; Aniline Compounds; Animals; Biotransformation; Carbon Monoxide; Guinea Pigs; Kinetics; Male; Methimazole; Microsomes, Liver; Polychlorinated Biphenyls; Proadifen; Structure-Activity Relationship; Superoxide Dismutase | 1981 |
Effects of inducers and/or inhibitors on metabolism of lysergic acid diethylamide in rat liver microsomes.
Topics: Animals; Biotransformation; Carbon Monoxide; Enzyme Induction; Enzyme Inhibitors; In Vitro Techniques; Lysergic Acid Diethylamide; Methylcholanthrene; Microsomes, Liver; NAD; Oxygen Consumption; Phenobarbital; Proadifen; Rats | 1980 |
Stereochemical aspects of the metabolism of phenprocoumon in rat liver microsomes.
Topics: 4-Hydroxycoumarins; Animals; Biotransformation; Carbon Monoxide; Chemical Phenomena; Chemistry; Hydroxylation; In Vitro Techniques; Metyrapone; Microsomes, Liver; NAD; Phenprocoumon; Proadifen; Rats; Stereoisomerism | 1981 |
The role of cytochrome P-450 in the synthesis of polar metabolites of aldosterone by microsomes of male rat liver.
Topics: Aldosterone; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1981 |
Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences.
Topics: Animals; Benzoflavones; Carbazoles; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Species Specificity | 1980 |
Microsomal conversion of SKF 525-A and SKF 8742-A.
Topics: Animals; Biotransformation; Carbon Monoxide; Dithiothreitol; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Proadifen; Rats | 1980 |
Metabolism of dihalomethanes to carbon monoxide. IV. Studies in isolated rat hepatocytes.
Topics: Animals; Carbon Monoxide; Hydrocarbons, Halogenated; In Vitro Techniques; Kinetics; Liver; Male; Methane; Methylcholanthrene; Phenobarbital; Proadifen; Rats | 1980 |
Cytochrome P450 in trypanosomatids.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Metyrapone; Microsomes, Liver; Pentamidine; Proadifen; Rats; Subcellular Fractions; Trypanosomatina | 1993 |
Biotransformation of glyceryl trinitrate by rat aortic cytochrome P450.
Topics: Animals; Aorta; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Kinetics; Microsomes; Microsomes, Liver; Nitroglycerin; Oxygen; Phenobarbital; Proadifen; Rats | 1993 |
Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta.
Topics: Animals; Aorta; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hemeproteins; Hypoxia; In Vitro Techniques; Male; Metyrapone; Nitric Oxide; Nitroglycerin; Proadifen; Rabbits; Vasodilation | 1993 |
Styrene metabolism in Exophiala jeanselmei and involvement of a cytochrome P-450-dependent styrene monooxygenase.
Topics: Air Pollutants; Biodegradation, Environmental; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Exophiala; Metyrapone; Oxygenases; Proadifen; Spectrophotometry; Styrene; Styrenes | 1996 |
Production of carbon monoxide by cytochrome P450 during iron-dependent lipid peroxidation.
Topics: alpha-Tocopherol; Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); In Vitro Techniques; Iron; Lipid Peroxidation; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Protoporphyrins; Rabbits; Steroid Hydroxylases | 2002 |