proadifen has been researched along with aminopyrine in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (89.29) | 18.7374 |
| 1990's | 5 (8.93) | 18.2507 |
| 2000's | 1 (1.79) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Nucci, A; Ferrini, B; Gregotti, C; Manzo, L; Rugarli, PL; Tarozzi, A | 1 |
| Powis, G | 1 |
| Hart, FE; Hew, JT; Willson, RA | 1 |
| Moilanen, ML; Pelkonen, O | 1 |
| Saitoh, M; Sasaki, K; Takayanagi, G | 1 |
| Pelkonen, O | 1 |
| Agosin, M; Capdevila, J; Naquira, C; Paulin, J | 1 |
| Boobis, AR; Powis, G | 1 |
| Kuga, T; Moroi, K; Satoh, T; Ushiyama, S | 1 |
| Ahokas, JT; KARKI, NT; Pelkonen, O | 1 |
| Gangolli, SD; Heading, CE; Lake, BG; Lloyd, AG; Phillips, JC | 1 |
| Chen, NQ; Holtzman, JL; Srivastava, SP | 1 |
| Hoshi, K; Igarashi, T; Kitagawa, H; Satoh, T; Senda, N; Ueno, K | 1 |
| Hanzlik, RP; Traiger, GJ; Vyas, KP | 1 |
| Horváth, I; Knittel, A; Venekei, I | 1 |
| Smith, DA | 1 |
| Beyerinck, RA; Brass, EP; Garrity, MJ | 1 |
| Bartsch, H; Hietanen, E; Kobljakov, V | 1 |
| Correia, MA; Mannering, GJ | 1 |
| Kamataki, T; Kitagawa, H | 1 |
| Bickel, MH; Gigon, PL | 1 |
| Castro, JA; Gomez, MI | 1 |
| Gigon, PL; Gillette, JR; Gram, TE | 2 |
| Mitoma, C; Tagg, J | 1 |
| Gillette, JR; Sasame, HA | 1 |
| Kato, R; Onoda, K; Takayanagi, M | 1 |
| Topham, JC | 1 |
| Ackermann, E | 1 |
| Sawyer, BC; Slater, TF | 1 |
| Kupfer, D; Levin, E | 1 |
| Allen, LM; Creaven, PJ | 1 |
| Cinti, DL; Schenkman, JB; Wilson, BJ | 1 |
| Dingell, JV; Heath, EC; Klausner, HA; Miller, KW | 1 |
| Filippich, LJ; Seawright, AA; Steele, DP | 1 |
| Kamataki, T; Kitada, M; Kitagawa, H | 1 |
| Kappas, A; Poland, A | 1 |
| Kato, R; Oshima, T; Takayanagi, M | 1 |
| Fujimoto, M; Kitahara, A; Miyao, K; Ogo, T | 1 |
| Dewaide, JH; Henderson, PT | 1 |
| Cornish, HH; Morrison, AB; Nelson, JM | 1 |
| Graham, PS; Hellyer, RO; Ryan, AJ | 1 |
| Aust, SD; Pederson, TC | 1 |
| Castro, JA; Cignoli, EV | 1 |
| Calderoni, FJ; Mitoma, C; Neubauer, SE; Tagg, JS; Tanabe, M; Yasuda, D | 1 |
| Huidobro, F; Huidobro, JP; Larraín, G | 1 |
| Avnimelech, M; Jondorf, WR; Simon, DC | 1 |
| Moldowan, MJ | 1 |
| Cook, DE; Past, MR | 1 |
| Kitagawa, H; Naminohira, S; Saito, H; Sakai, T; Ueno, K | 1 |
| Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW | 2 |
| Ishikawa, K; Sato, Y; Shibanoki, S; Sugahara, M | 1 |
| Archakov, AI; Avdeenko, YL; Bulko, TV; Moskvitina, TL; Shumyantseva, VV | 1 |
| Linster, CL; Van Schaftingen, E | 1 |
| FOUTS, JR; ROGERS, LA | 1 |
56 other study(ies) available for proadifen and aminopyrine
| Article | Year |
|---|---|
Aminopyrine: metabolism and effects in the rat after administration of inhibitors of hepatic monooxygenases.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Female; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Oxyquinoline; Proadifen; Rats; Time Factors | 1979 |
Effect of a single oral dose of methanol, ethanol and propan-2-ol on the hepatic microsomal metabolism of foreign compounds in the rat.
Topics: 1-Propanol; Acetone; Administration, Oral; Aminopyrine; Aniline Compounds; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport Complex IV; Ethanol; Hydroxylation; Male; Methanol; Methylation; Microsomes, Liver; Proadifen; Rats | 1975 |
Breath analysis of 14CO2 production from aminopyrine in the normal rat.
Topics: Aminopyrine; Animals; Breath Tests; Carbon Dioxide; Disulfiram; Fasting; Male; Phenobarbital; Proadifen; Rats; Time Factors; Tissue Distribution | 1979 |
The specificity and multiplicity of human placental xenobiotic-metabolizing monooxygenase system studied by potential substrates, inhibitors and gel electrophoresis.
Topics: Aldrin; Aminopyrine; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Biotransformation; Biphenyl Compounds; Coumarins; Electrophoresis, Polyacrylamide Gel; Female; Flavonoids; Humans; Microsomes; Placenta; Pregnancy; Proadifen; Smoking | 1979 |
[Drug interaction on antitumor drugs I. Antitumor activity of cyclophosphamide in mice consecutively administered aminopyrine, chlorpromazine, or morphine (author's transl)].
Topics: Aminopyrine; Animals; Antineoplastic Agents; Chlorpromazine; Cycloheximide; Cyclophosphamide; Drug Interactions; Male; Mice; Morphine; Pentobarbital; Proadifen; Sleep | 1979 |
Differential inhibition of aryl hydrocarbon hydroxylase in human foetal liver, adrenal gland and placenta*.
Topics: Adrenal Glands; Aminopyrine; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Female; Flavonoids; Humans; Liver; Male; Maternal-Fetal Exchange; Metyrapone; Placenta; Pregnancy; Proadifen; Rats; Smoking; Testosterone | 1977 |
Cytochrome P-450 and drug metabolism in Trypanosoma cruzi: effects of phenobarbital.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Cytochrome P-450 Enzyme System; Metyrapone; Microsomes; Mixed Function Oxygenases; Oxidoreductases, O-Demethylating; Phenobarbital; Proadifen; Ribosomes; Trypanosoma cruzi | 1976 |
Effect of washing the hepatic microsomal fraction in sucrose solutions and in sucrose solution containing EDTA upon the metabolism of foreign compounds.
Topics: Acetone; Aminopyrine; Animals; Edetic Acid; Female; In Vitro Techniques; Lipid Metabolism; Manganese; Microsomes, Liver; Mixed Function Oxygenases; Potassium Chloride; Proadifen; Rats; Sucrose | 1975 |
Enzyme induction by repeated adminstration of tetrachlorvinphos in rats.
Topics: Aminopyrine; Animals; Cholinesterases; Dealkylation; Enzyme Induction; In Vitro Techniques; Inactivation, Metabolic; Insecticides; Male; Microsomes, Liver; Phenobarbital; Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester; Proadifen; Rats; Tetrachlorvinphos; Time Factors | 1976 |
Metabolism of polycyclic hydrocarbons by a highly active aryl hydrocarbon hydroxylase system in the liver of a trout species.
Topics: Aminopyrine; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Flavonoids; Kinetics; Male; Microsomes, Liver; Proadifen; Rats; Species Specificity; Trout | 1975 |
Studies on the metabolism of dimethylnitrosamine in the rat. II. The effects of phenobarbitone and 20-methylcholanthrene on the in vitro and in vivo metabolism and acute toxicity of dimethylnitrosamine in young and mature rats.
Topics: Age Factors; Aminopyrine; Aniline Hydroxylase; Animals; Carbon Dioxide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Female; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sex Factors | 1975 |
The effect of substrates and inhibitors of cytochrome P-450 on the NADPH inhibition of the ATP-dependent, hepatic, microsomal calcium pump.
Topics: Aminopyrine; Animals; Benzphetamine; Calcium; Calcium-Transporting ATPases; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Proadifen; Rats; Rats, Inbred Strains | 1990 |
Effects of co-administration of monomethylaminoantipyrine with diethylaminoethyl 2,2-diphenylvalerate (SKF 525-A) on gamma-glutamyltranspeptidase, glutathione S-transferase and hepatic drug metabolizing enzyme activities in rats.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Cytosol; Dipyrone; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Liver; Male; Mixed Function Oxygenases; Proadifen; Pyrazolones; Rats; Rats, Inbred Strains | 1986 |
Effect of inhibitors of alpha-naphthylisothiocyanate-induced hepatotoxicity on the in vitro metabolism of alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Aminopyrine; Animals; Bilirubin; Biotransformation; Chromatography, Gas; Ditiocarb; Ethionamide; Hyperbilirubinemia; Imidazoles; Kinetics; Male; Methimazole; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Thiocyanates | 1985 |
Effect of a heme-peptide derived from cytochrome-c on lipid peroxidation. II. Experiments with liver microsomes.
Topics: Adenosine Diphosphate; Aminopyrine; Animals; Cytochrome c Group; Cytochromes c; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Mice; Microsomes, Liver; Oxygen Consumption; Peptide Fragments; Proadifen | 1986 |
Aminopyrine N-demethylation in young, old and tumour bearing B6C3 F1 mice.
Topics: Aging; Aminopyrine; Animals; Carbon Dioxide; Dealkylation; Female; Kinetics; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Proadifen | 1987 |
Inhibition of prostaglandin E2 catabolism and potentiation of hepatic prostaglandin E2 action in rat hepatocytes by inhibitors of oxidative metabolism.
Topics: Aminopyrine; Animals; Benzoflavones; Dinoprostone; Glucagon; Glycogen; Liver; Male; Metyrapone; Oxidation-Reduction; Proadifen; Prostaglandins E; Rats; Rats, Inbred Strains | 1988 |
Role of different cytochrome P-450 isozymes in the demethylation of various substrates.
Topics: 1,2-Dimethylhydrazine; Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Dimethylhydrazines; Dimethylnitrosamine; In Vitro Techniques; Isoenzymes; Male; Metyrapone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Proadifen; Rats; Substrate Specificity | 1986 |
Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. II. Role of the type I drug-binding site of cytochrome P-450.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Codeine; Cyanides; Cytochrome P-450 Enzyme System; Drug Synergism; Female; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Phospholipases; Proadifen; Protein Binding; Rats | 1973 |
Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Cobalt; Codeine; Edetic Acid; In Vitro Techniques; Iron; Kinetics; Lipid Metabolism; Lipids; Male; Manganese; Microsomes, Liver; Morphinans; Peroxides; Phenanthrolines; Proadifen; Rats | 1973 |
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation | 1971 |
Studies on the irreversible binding of 14 C-CCl 4 to microsomal lipids in rats under varying experimental conditions.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Animals; Carbon Isotopes; Carbon Tetrachloride; Castration; Centrifugation, Density Gradient; Edetic Acid; Ethylamines; Gonads; Hydroxylation; Lipid Metabolism; Liver; Male; Malonates; Microsomes, Liver; Niacinamide; Phenobarbital; Phenols; Proadifen; Rats; Sleep; Sucrose | 1972 |
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases | 1968 |
Studies on the microsomal drug-metabolizing enzyme system--effect of isooctane and pyridine nucleotides.
Topics: Acetanilides; Adenosine Triphosphate; Aminopyrine; Aniline Compounds; Animals; Guanine Nucleotides; Hydrocarbons; Kinetics; Lipids; Liver; Male; Microsomes; NADP; Nitrophenols; Nucleotides; Proadifen; Proteins; Pyridines; Rabbits; Rats; RNA | 1968 |
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates | 1969 |
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry | 1969 |
Species difference in the inhibition of drug metabolism by liver microsomes by different inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cocaine; Depression, Chemical; Drug Antagonism; Ethylamines; Hexobarbital; Histamine H1 Antagonists; Kinetics; Male; Meperidine; Mice; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Pentobarbital; Pharmaceutical Preparations; Phenacetin; Phenylhydrazines; Piperazines; Proadifen; Rabbits; Rats; Species Specificity; Zoxazolamine | 1969 |
Relationship between difference spectra and metabolism. Barbiturates, drug interaction and species difference.
Topics: Acetanilides; Acetates; Amino Alcohols; Aminopyrine; Aniline Compounds; Animals; Barbiturates; Binding Sites; Chemical Phenomena; Chemistry; Chlorpromazine; Cytochromes; Drug Antagonism; Drug Synergism; Ethanolamines; Hexobarbital; Macaca; Male; Mice; Microsomes, Liver; Pentobarbital; Phenobarbital; Proadifen; Propranolol; Protein Binding; Rats; Sleep; Species Specificity; Spectrophotometry; Thiazoles; Tremorine | 1970 |
[Demethylation of aminophenazone and codeine in human liver. An investigation of microsomal electron transport].
Topics: Aminopyrine; Animals; Codeine; Cyanides; Cytochromes; Dealkylation; Electron Spin Resonance Spectroscopy; Electron Transport; Female; Glucosephosphate Dehydrogenase; Half-Life; Humans; Kinetics; Lysosomes; Male; Mathematics; Methylation; Microsomes, Liver; Middle Aged; Mitochondria, Liver; NADP; Niacinamide; Oxidoreductases; Pentosephosphates; Phosphogluconate Dehydrogenase; Proadifen; Rats; Sex Factors; Species Specificity; Spectrophotometry | 1970 |
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Interaction sites in the endoplasmic reticulum.
Topics: Aldehydes; Aminopyrine; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloromercuribenzoates; Cytochromes; Electron Transport; Endoplasmic Reticulum; In Vitro Techniques; Lipid Metabolism; Liver; Malonates; Microsomes, Liver; NADP; Niacinamide; Peroxides; Proadifen; Rats | 1971 |
Monooxygenase drug metabolizing activity in CaCl 2 -aggregated hepatic microsomes from rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Calcium Chloride; Carbon Monoxide; Chlorine; Dronabinol; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats | 1972 |
In vitro activation of isophosphamide (NSC-109724), a new oxazaphosphorine, by rat liver microsomes.
Topics: Alkylating Agents; Alkylation; Aminopyrine; Aniline Compounds; Animals; Cyclic P-Oxides; Cyclophosphamide; Dealkylation; DNA; Enzyme Activation; Ethylamines; Kinetics; Liver; Male; Microsomes, Liver; Morphinans; NADP; Oxazines; Oxidoreductases; Phenobarbital; Phosphoranes; Proadifen; Proteins; Rats; RNA | 1972 |
Dimethylaminoethyl 2,2-diphenylvalerate HCl (SKF 525-A)--in vivo and in vitro effects of metabolism by rat liver microsomes--formation of an oxygenated complex.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Body Weight; Cytochrome P-450 Enzyme System; Dealkylation; Female; Male; Microsomes, Liver; Organ Size; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Proadifen; Rats; Spectrum Analysis; Time Factors | 1972 |
The intracellular localization of 9 -tetrahydrocannabinol in liver and its effects on drug metabolism in vitro.
Topics: Aminopyrine; Animals; Benzoates; Cannabis; Carbon Isotopes; Cell Nucleus; Dealkylation; Dronabinol; Estradiol; Glucuronates; Hexobarbital; Hexosyltransferases; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Mitochondria, Liver; Nitrophenols; Oxidation-Reduction; Pharmaceutical Preparations; Proadifen; Rats; Tritium | 1973 |
The effect of carbon disulphide used in combination with carbon tetrachloride on the toxicity of the latter drug for sheep.
Topics: Aminopyrine; Animals; Biopsy; Carbon Disulfide; Carbon Radioisotopes; Carbon Tetrachloride; DDT; Diet; Drug Combinations; Fasciola hepatica; Liver; Male; Microsomes, Liver; Phenobarbital; Proadifen; Sheep | 1973 |
Substrate induced difference spectrum of microsomal P-450 in human liver.
Topics: Aminopyrine; Aniline Compounds; Hexobarbital; Humans; Microsomes, Liver; Pigments, Biological; Proadifen; Spectrophotometry | 1971 |
The metabolism of aminopyrine in chick embryo hepatic cell culture: effects of competitive substrates and carbon monoxide.
Topics: Aminopyrine; Animals; Antipyrine; Carbon Monoxide; Cells, Cultured; Chick Embryo; Dealkylation; Fatty Acids; Hexobarbital; Intestinal Mucosa; Kidney; Kinetics; Liver; Oxygen Consumption; Piperonyl Butoxide; Proadifen; Testosterone | 1971 |
Differences in the oxidative metabolism of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine | 1969 |
[Analgesic effect of 2-methylaminoethyl 2,3-dihydrobenzofuran (EPS-4032); mode of action in mice].
Topics: 5-Hydroxytryptophan; Aminopyrine; Analgesics; Animals; Benzofurans; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Drug Tolerance; Lethal Dose 50; Levallorphan; Male; Mice; Morphine; Nialamide; Pargyline; Phenobarbital; Proadifen; Reserpine; Tetrabenazine; Time Factors | 1971 |
Metabolism of drugs in isolated rat hepatocytes.
Topics: Aminopyrine; Aniline Compounds; Animals; Cell Membrane Permeability; DNA; In Vitro Techniques; Liver; Male; Microsomes, Liver; Nitrophenols; Oxygen Consumption; Proadifen; Rats; Tissue Extracts; Ultrasonics | 1969 |
Effect of fasting on the toxicity and serum concentration of aminopyrine in rats.
Topics: Administration, Oral; Aminopyrine; Animals; Fasting; Injections, Intraperitoneal; Male; Proadifen; Rats | 1970 |
The kinetics of inhibition of drug metabolism in vitro by some naturally occurring compounds.
Topics: Aminopyrine; Aniline Compounds; Animals; Dioxoles; In Vitro Techniques; Ketones; Kinetics; Liver; Proadifen; Rats | 1970 |
Aminopyrine demethylase. Kinetic evidence for multiple microsomal activities.
Topics: Aminopyrine; Animals; Carbon Monoxide; Chromatography, Thin Layer; Cytochromes; Dealkylation; Enzyme Induction; Ethionine; Goats; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Proadifen; Rats; Spectrophotometry; Stimulation, Chemical; Sulfites | 1970 |
Effect of inhibitors of drug metabolizing enzymes on carbon tetrachloride hepatotoxicity.
Topics: Aminopyrine; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Depression, Chemical; Drug Antagonism; Ethylamines; Imipramine; Isocitrate Dehydrogenase; Lipid Metabolism; Liver; Liver Diseases; Male; Malonates; Microsomes, Liver; Necrosis; Organ Size; Pentobarbital; Peroxidases; Peroxides; Proadifen; Rats; Sleep; Stimulation, Chemical | 1971 |
Effects of various chemical agents on drug metabolism and cholesterol biosynthesis.
Topics: Acetanilides; Acetates; Aminopyrine; Animals; Anticholesteremic Agents; Benzopyrenes; Carbon Isotopes; Chloramphenicol; Cholesterol; Depression, Chemical; Drug Synergism; Ethers; Ethylamines; Hexobarbital; Insecticides; Iproniazid; Liver; Male; Mevalonic Acid; Microsomes; Nitrophenols; Phenobarbital; Proadifen; Rabbits; Rats; Sleep; Time Factors | 1968 |
Tolerance to morphine in the white mice.
Topics: Aminopyrine; Animals; Behavior, Animal; Body Temperature; Body Weight; Drug Tolerance; Mice; Morphine; Phenobarbital; Proadifen; Sodium Salicylate | 1968 |
Further studies on the stimulation of L-(14C)-amino acid incorporation with cycloheximide.
Topics: Aminopyrine; Aniline Compounds; Animals; Antifungal Agents; Antipyrine; Body Weight; Carbon Isotopes; Cycloheximide; Female; Growth; Hexobarbital; In Vitro Techniques; Liver; Magnesium; Microsomes; Organ Size; Phenylalanine; Proadifen; Rats; RNA; RNA, Messenger; Sleep; Sulfonamides | 1966 |
A noninvasive method for the study of hepatic drug metabolism in rodents: aminopyrine metabolism in rats.
Topics: Aminopyrine; Animals; Half-Life; Liver; Male; Proadifen; Rats; Rats, Inbred Strains; Saliva | 1983 |
Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Liver; Male; Mitochondria, Liver; Proadifen; Rats; Rats, Inbred Strains; Substrate Specificity | 1982 |
Drug metabolism and fetal toxicity: changes in fetal toxicity of aminopyrine by variation of drug metabolizing enzyme activity in mice.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cobalt; Female; Fetal Death; Male; Methylcholanthrene; Metyrapone; Mice; Mice, Inbred ICR; Pharmaceutical Preparations; Pregnancy; Proadifen | 1981 |
Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity.
Topics: Aminopyrine; Animals; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Induction; Free Radical Scavengers; Ketoconazole; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley | 1994 |
Measurement and pharmacokinetic analysis of imipramine and its metabolite by brain microdialysis.
Topics: Aminopyrine; Animals; Brain; Chromatography, High Pressure Liquid; Desipramine; Electrochemistry; Half-Life; Imipramine; Male; Microdialysis; Proadifen; Rats; Rats, Wistar | 1994 |
Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Catalase; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Ketoconazole; Lipid Peroxidation; Male; Proadifen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 1993 |
Hydrogen peroxide-supported activities of semisynthetic flavocytochrome 2B4.
Topics: Aminopyrine; Aniline Compounds; Anisoles; Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 Enzyme System; Enzyme Activation; Glycyrrhiza; Hydrogen Peroxide; Kinetics; Luminescent Measurements; Luminol; Plants, Medicinal; Proadifen; Sodium Cyanide; Steroid Hydroxylases | 1998 |
Rapid stimulation of free glucuronate formation by non-glucuronidable xenobiotics in isolated rat hepatocytes.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Ascorbic Acid; Barbital; Buthionine Sulfoximine; Cells, Cultured; Chlorobutanol; Chromatography, High Pressure Liquid; Clotrimazole; Diamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galactosamine; Glucuronates; Glucuronic Acid; Hepatocytes; Imidazoles; Imidazolidines; Metyrapone; Models, Chemical; Preservatives, Pharmaceutical; Proadifen; Rats; Rats, Wistar; Resorcinols; Time Factors; Xenobiotics; Xylulose | 2003 |
SOME OF THE INTERACTIONS OF SKF 525-A WITH HEPATIC MICROSOMES.
Topics: Aminopyrine; Codeine; Dialysis; Fatty Acids; Hexobarbital; Iproniazid; Liver; Liver Glycogen; Metabolism; Microsomes; Microsomes, Liver; Proadifen; Rats; Renal Dialysis; Research | 1964 |