proadifen has been researched along with alpha-naphthoflavone in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (61.29) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirobe, M; Ohi, H; Ohta, S; Takahara, E | 1 |
| Daniels, JM; Massey, TE | 1 |
| Giri, SN; Siegel, DM | 1 |
| Bender, PE; Eckardt, RD; Leonard, TB; Newton, JF; Romano, MC; Straub, KM | 1 |
| Hayashi, S; Ishikawa, T; Murakami, K; Noshiro, M; Okuda, K; Shimosato, T | 1 |
| Beyerinck, RA; Brass, EP; Garrity, MJ | 1 |
| Numazawa, M; Satoh, S | 1 |
| Flory, W; Henk, WG; Turk, MA | 1 |
| Buhler, DR; Carpenter, HM; Williams, DE | 1 |
| Kuwahara, S; Mannering, GJ | 1 |
| Ahokas, JT; Pelkonen, O; Sotaniemi, EA | 1 |
| Finnen, MJ; Shuster, S | 1 |
| Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
| Nagata, K; Yoshihara, S; Yoshimura, H | 1 |
| Hall, ST; Houston, JB; Rhodes, JC | 1 |
| Cazer, FD; Hart, RW; Sheikh, YM; Witiak, DT | 1 |
| Della Porta, G; Dragani, TA; Sozzi, G | 1 |
| DePierre, JW; Meijer, J | 1 |
| Ishidate, M; Miyata, R; Nohmi, T; Yoshikawa, K | 1 |
| Grafstöm, R; Stohs, SJ | 1 |
| Ahokas, JT; Kärki, NT; Pelkonen, O; Saarni, H; Sotaniemi, EA | 1 |
| Benford, DJ; Bridges, JW | 1 |
| Huang, H; Jurima-Romet, M; Paul, CJ; Solomonraj, G; Thomas, BH | 1 |
| Black, KA; Novicki, DL; Smith, GJ; Vincent, JL | 1 |
| Melancon, MJ; Renauld, AE; Sordillo, LM | 1 |
| Burnstein, KL; Hayakawa, K; Kizu, R; Klinge, CM; Mizokami, A; Okamura, K; Toriba, A | 1 |
| Akao, T; Hattori, M; Nakamura, N; Sasahara, M; Takagawa, K; Tang, J; Wang, ZT | 1 |
| Greenhaw, J; Salminen, WF; Shi, Q; Yang, X | 1 |
| Beltrán-Ramírez, O; Pérez, RM; Sierra-Santoyo, A; Villa-Treviño, S | 1 |
| Kubickova, B; Martinkova, M; Stiborova, M | 1 |
| Greenhaw, J; Salminen, WF; Shi, Q | 1 |
31 other study(ies) available for proadifen and alpha-naphthoflavone
| Article | Year |
|---|---|
Effects of oxygen concentration on the metabolism of anisole homologues by rat liver microsomes.
Topics: Animals; Anisoles; Benzoflavones; In Vitro Techniques; Male; Microsomes, Liver; Oxygen; Phenobarbital; Phenyl Ethers; Proadifen; Rats; Rats, Wistar | 1992 |
Modulation of aflatoxin B1 biotransformation in rabbit pulmonary and hepatic microsomes.
Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; Isoenzymes; Kinetics; Lung; Male; Microsomes; Microsomes, Liver; NADP; Oxidoreductases; Proadifen; Rabbits | 1992 |
Characterization of covalent binding of [14C]-2-chloro-4-acetotoluidide to microsomes of starling liver and kidney.
Topics: Animals; Benzoflavones; Birds; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Glutathione; In Vitro Techniques; Kidney; Kinetics; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Protein Binding; Sulfhydryl Compounds; Toluidines | 1991 |
Biochemical characterization of hepatic microsomal leukotriene B4 hydroxylases.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Kinetics; Leukotriene B4; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Pyrimidines; Rats; Rats, Inbred F344; Temperature | 1987 |
Aryl hydrocarbon hydroxylase activity in rat submandibular glands.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Metyrapone; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Submandibular Gland; Time Factors | 1986 |
Inhibition of prostaglandin E2 catabolism and potentiation of hepatic prostaglandin E2 action in rat hepatocytes by inhibitors of oxidative metabolism.
Topics: Aminopyrine; Animals; Benzoflavones; Dinoprostone; Glucagon; Glycogen; Liver; Male; Metyrapone; Oxidation-Reduction; Proadifen; Prostaglandins E; Rats; Rats, Inbred Strains | 1988 |
Kinetic studies of inhibition of estradiol 2- and 16 alpha-hydroxylases in rat liver microsomes with various cytochrome P-450 inhibitors.
Topics: Aminoglutethimide; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 2; Hydroxylation; Kinetics; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1988 |
Chemical modulation of 3-methylindole toxicosis in mice: effect on bronchiolar and olfactory mucosal injury.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bronchi; Epithelium; Female; Flavonoids; Glutathione; Indoles; Male; Maleates; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Nasal Mucosa; Phenobarbital; Piperonyl Butoxide; Proadifen; Sex Factors; Skatole | 1986 |
Hexachlorobenzene-induced porphyria in Japanese quail: an in vitro study of changes in cytochrome P-450 and monooxygenases.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Chlorobenzenes; Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxygenases; Porphyrias; Proadifen | 1985 |
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats | 1985 |
Coumarin 7-hydroxylase activity in human liver microsomes. Properties of the enzyme and interspecies comparisons.
Topics: Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Humans; Kinetics; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Phase 1 and Phase 2 drug metabolism in isolated epidermal cells from adult hairless mice and in whole human hair follicles.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Epidermis; Female; Hair; Humans; Kinetics; Male; Mice; Mice, Hairless; Proadifen; Spectrometry, Fluorescence; Umbelliferones | 1985 |
Nature of N-nitrosodimethylamine demethylase in hepatic microsomes of rats.
Topics: Aminoacetonitrile; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzoflavones; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Imidazoles; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Monoamine Oxidase; Niacinamide; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Pyrazoles; Rats; Rats, Inbred Strains; Tranylcypromine | 1984 |
Different responsiveness of hepatic and pulmonary microsomal mixed function oxidases to phenobarbital-type and 3-methylcholanthrene-type polychlorinated biphenyls in rats.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Inhibition of antipyrine metabolite formation in rats in vivo.
Topics: Animals; Antipyrine; Benzoflavones; Cimetidine; Cytochrome P-450 Enzyme System; Male; Metyrapone; Proadifen; Rats; Rats, Inbred Strains | 1984 |
Biotransformation of 7, 12-dimethylbenz(a)anthracene(DMBA): on the genesis of DMBA-trans-dihydrodiols and DMBA-7- and 12-methylhydroxylated metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Carbon Disulfide; Flavonoids; Liver; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship | 1980 |
Effect of enzymatic induction and inhibition on cyclophosphamide-induced sister chromatid exchange in vivo.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bromodeoxyuridine; Crossing Over, Genetic; Cyclophosphamide; Enzyme Induction; Male; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Pentobarbital; Proadifen; Sister Chromatid Exchange; Zoxazolamine | 1983 |
Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system.
Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Stilbenes; Testosterone | 1983 |
Effects of 7, 8-benzoflavone and SKF 525-A on the enzyme-mediated mutagenicity of phenylenediamines.
Topics: Animals; Benzoflavones; Flavonoids; Male; Microsomes; Mixed Function Oxygenases; Mutagens; Phenylenediamines; Proadifen; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1982 |
Inhibitors of 7-ethoxyresorufin and 7-ethoxycoumarin de-ethylases in rat small intestinal microsomes and cells.
Topics: Animals; Benzoflavones; Benzopyrenes; Coumarins; Cytochrome P-450 CYP1A1; Female; Intestine, Small; Methylcholanthrene; Metyrapone; Microsomes; Oxidoreductases; Proadifen; Rats; Rats, Inbred Strains; Rotenone | 1981 |
Dose-dependent effects of medrozyprogesterone acetate on the hepatic drug-metabolizing enzyme system in rats.
Topics: Animals; Benzoflavones; Benzopyrene Hydroxylase; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; In Vitro Techniques; Male; Medroxyprogesterone; Microsomes, Liver; Mixed Function Oxygenases; Proadifen; Rats; Sex Factors | 1980 |
Characterization of the activation of hepatic microsomal hydroxylation by betamethasone and alpha naphthoflavone.
Topics: Animals; Benzoflavones; Betamethasone; Enzyme Activation; Flavonoids; Hydroxylation; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats | 1980 |
Metabolism of phenazopyridine by isolated rat hepatocytes.
Topics: Animals; Benzoflavones; Detergents; Enzyme Induction; In Vitro Techniques; Indomethacin; Liver; Male; Metyrapone; Octoxynol; Phenazopyridine; Polyethylene Glycols; Proadifen; Rats; Rats, Wistar | 1993 |
Flow cytometric analysis of xenobiotic metabolism activity in isolated rat hepatocytes.
Topics: Animals; Benzoflavones; Flow Cytometry; Fluoresceins; Light; Liver; Male; Metyrapone; Mixed Function Oxygenases; Proadifen; Rats; Xenobiotics | 1993 |
Identification of in vitro cytochrome P450 modulators to detect induction by prototype inducers in the mallard duckling (Anas platyrhynchos).
Topics: Animals; Benzimidazoles; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Ducks; Enzyme Induction; Microsomes, Liver; Oxazines; Oxidoreductases; Phenobarbital; Polychlorinated Biphenyls; Proadifen | 1999 |
Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells.
Topics: Adenocarcinoma; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Benzoflavones; beta-Galactosidase; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Luciferases; Male; Nitriles; Polycyclic Aromatic Hydrocarbons; Proadifen; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Receptors, Aryl Hydrocarbon; Saccharomyces cerevisiae; Tosyl Compounds; Vehicle Emissions | 2003 |
In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors.
Topics: Alanine Transaminase; Animals; Antitussive Agents; Aspartate Aminotransferases; Asteraceae; Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Drugs, Chinese Herbal; Esterases; Expectorants; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Monocrotaline; Phenylmethylsulfonyl Fluoride; Proadifen; Pyrrolizidine Alkaloids; Rats; Rats, Sprague-Dawley; Tritolyl Phosphates | 2007 |
Hepatic cytochrome P450s attenuate the cytotoxicity induced by leflunomide and its active metabolite A77 1726 in primary cultured rat hepatocytes.
Topics: Aniline Compounds; Animals; Benzoflavones; Biomarkers; Cell Survival; Cells, Cultured; Crotonates; Cytochrome P-450 Enzyme System; Hepatocytes; Hydroxybutyrates; Inactivation, Metabolic; Isoxazoles; Ketoconazole; Leflunomide; Liver; Male; Nitriles; Primary Cell Culture; Proadifen; Rats; Rats, Sprague-Dawley; Ticlopidine; Toluidines; Triazoles | 2011 |
Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Caffeic Acids; Carcinogenicity Tests; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochromes; Diethylnitrosamine; Disease Models, Animal; Liver Neoplasms, Experimental; Male; Phenylethyl Alcohol; Proadifen; Rats; Rats, Inbred F344; Steroid Hydroxylases | 2012 |
Effects of cytochrome P450 inhibitors on peroxidase activity.
Topics: Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ellipticines; Enzyme Activation; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Ketoconazole; Metyrapone; Piperonyl Butoxide; Proadifen; Quinidine; Structure-Activity Relationship; Substrate Specificity; Sulfaphenazole; Triazoles; Troleandomycin | 2012 |
Inhibition of cytochrome P450s enhances (+)-usnic acid cytotoxicity in primary cultured rat hepatocytes.
Topics: Animals; Benzoflavones; Benzofurans; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dietary Supplements; Enzyme Inhibitors; Hepatocytes; Ketoconazole; Liver; Male; Mitochondria; Proadifen; Rats; Rats, Sprague-Dawley; Ticlopidine | 2014 |