Page last updated: 2024-08-16

proadifen and 8,11,14-eicosatrienoic acid

proadifen has been researched along with 8,11,14-eicosatrienoic acid in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's7 (70.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bend, JR; Knickle, LC1
Conners, MS; Dunn, MW; Schwartzman, ML; Stoltz, RA1
Alfonso, A; Gill, DL; Graber, MN1
Dai, J; Graham, L; Liao, JK; Node, K; Ruan, XL; Yang, SX; Zeldin, DC1
Chiribiri, A; Gattullo, D; Pagliaro, P; Paolocci, N; Penna, C; Rastaldo, R1
Bradbury, JA; Conte, MS; Liao, JK; Sui, X; Sun, J; Zeldin, DC1
Earley, S; Pastuszyn, A; Walker, BR1
Aronoff, DM; Boutaud, O; Kozak, A; Kozak, W1
Metea, MR; Newman, EA1
Kodama, Y; Lv, X; Nakahata, N; Ohizumi, Y; Toriniwa, Y; Yoshida, M1

Other Studies

10 other study(ies) available for proadifen and 8,11,14-eicosatrienoic acid

ArticleYear
Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids.
    Molecular pharmacology, 1994, Volume: 45, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Guinea Pigs; Lung; Male; Metyrapone; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Triazoles

1994
Effect of metabolic inhibitors on arachidonic acid metabolism in the corneal epithelium: evidence for cytochrome P450-mediated reactions.
    Journal of ocular pharmacology, 1994,Spring, Volume: 10, Issue:1

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cattle; Chromatography, High Pressure Liquid; Clotrimazole; Cornea; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Epithelium; Hydroxyeicosatetraenoic Acids; Lipoxygenase Inhibitors; Microsomes; Proadifen; Rabbits

1994
Recovery of Ca2+ pools and growth in Ca2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid.
    The Journal of biological chemistry, 1997, Nov-21, Volume: 272, Issue:47

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Cycle; Cell Division; Cells, Cultured; Cricetinae; Enzyme Inhibitors; Indoles; Masoprocol; Metyrapone; Muscle, Smooth; Proadifen; Signal Transduction; Thapsigargin

1997
Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids.
    The Journal of biological chemistry, 2001, May-11, Volume: 276, Issue:19

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Aorta; Atropine Derivatives; Cattle; Cells, Cultured; Cyclic AMP; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Oxygenases; Polymerase Chain Reaction; Proadifen; Promoter Regions, Genetic; Saphenous Vein; Tissue Plasminogen Activator; Transcription, Genetic; Transfection

2001
Cytochrome P-450 metabolite of arachidonic acid mediates bradykinin-induced negative inotropic effect.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Blood Pressure; Bradykinin; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Indomethacin; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Octoxynol; Proadifen; Rats; Rats, Wistar; Tachyphylaxis; Triazoles; Ventricular Function, Left

2001
Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids.
    Circulation research, 2002, May-17, Volume: 90, Issue:9

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Becaplermin; Cell Division; Cell Line; Cell Movement; Cells, Cultured; Clotrimazole; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; Humans; Male; Muscle, Smooth, Vascular; Oxygenases; Platelet-Derived Growth Factor; Proadifen; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar

2002
Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Calcium Channel Blockers; Cell Membrane; Chronic Disease; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hypoxia; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Oxygenases; Potassium Channels, Calcium-Activated; Proadifen; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Vasoconstriction

2003
11,12-epoxyeicosatrienoic acid attenuates synthesis of prostaglandin E2 in rat monocytes stimulated with lipopolysaccharide.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:7

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Lipopolysaccharides; Male; Monocytes; Proadifen; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Time Factors

2003
Glial cells dilate and constrict blood vessels: a mechanism of neurovascular coupling.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-15, Volume: 26, Issue:11

    Topics: 8,11,14-Eicosatrienoic Acid; Adenosine Triphosphate; Amidines; Animals; Arterioles; Calcium Signaling; Caproates; Cyclic N-Oxides; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Eye Proteins; Hydrazines; Hydroxyeicosatetraenoic Acids; Imidazoles; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Miconazole; Neuroglia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Photolysis; Proadifen; Purinergic Antagonists; Rats; Rats, Long-Evans; Retinal Vessels; Signal Transduction; Vasoconstriction; Vasodilation; Vasomotor System

2006
Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dinoprostone; Enzyme Activation; Oleanolic Acid; Oxygenases; Proadifen; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger

2006